SG11201807069XA - Nucleic acid sequencing method and system employing enhanced detection of nucleotide-specific ternary complex formation - Google Patents
Nucleic acid sequencing method and system employing enhanced detection of nucleotide-specific ternary complex formationInfo
- Publication number
- SG11201807069XA SG11201807069XA SG11201807069XA SG11201807069XA SG11201807069XA SG 11201807069X A SG11201807069X A SG 11201807069XA SG 11201807069X A SG11201807069X A SG 11201807069XA SG 11201807069X A SG11201807069X A SG 11201807069XA SG 11201807069X A SG11201807069X A SG 11201807069XA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- nucleotide
- nucleic acid
- rule
- applicant
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/10—Nucleotidyl transfering
- C12Q2521/101—DNA polymerase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/113—Time
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/137—Concentration of a component of medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2533/00—Reactions characterised by the enzymatic reaction principle used
- C12Q2533/10—Reactions characterised by the enzymatic reaction principle used the purpose being to increase the length of an oligonucleotide strand
- C12Q2533/101—Primer extension
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662326356P | 2016-04-22 | 2016-04-22 | |
| PCT/US2017/028878 WO2017184996A1 (en) | 2016-04-22 | 2017-04-21 | Nucleic acid sequencing method and system employing enhanced detection of nucleotide-specific ternary complex formation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201807069XA true SG11201807069XA (en) | 2018-09-27 |
Family
ID=58664858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201807069XA SG11201807069XA (en) | 2016-04-22 | 2017-04-21 | Nucleic acid sequencing method and system employing enhanced detection of nucleotide-specific ternary complex formation |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10982264B2 (ko) |
| EP (1) | EP3445870B1 (ko) |
| JP (1) | JP2019512209A (ko) |
| KR (2) | KR102254451B1 (ko) |
| CN (1) | CN109072297B (ko) |
| AU (1) | AU2017254688B2 (ko) |
| CA (1) | CA3011635C (ko) |
| SG (1) | SG11201807069XA (ko) |
| WO (1) | WO2017184996A1 (ko) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201807069XA (en) | 2016-04-22 | 2018-09-27 | Omniome Inc | Nucleic acid sequencing method and system employing enhanced detection of nucleotide-specific ternary complex formation |
| AU2017258619B2 (en) | 2016-04-29 | 2020-05-14 | Pacific Biosciences Of California, Inc. | Sequencing method employing ternary complex destabilization to identify cognate nucleotides |
| JP6828140B2 (ja) * | 2016-08-15 | 2021-02-10 | オムニオム インコーポレイテッドＯｍｎｉｏｍｅ， Ｉｎｃ． | 核酸をシーケンシングするための方法及びシステム |
| WO2018034780A1 (en) | 2016-08-15 | 2018-02-22 | Omniome, Inc. | Sequencing method for rapid identification and processing of cognate nucleotide pairs |
| AU2017386515B2 (en) * | 2016-12-30 | 2021-08-19 | Pacific Biosciences Of California, Inc. | Method and system employing distinguishable polymerases for detecting ternary complexes and identifying cognate nucleotides |
| US10161003B2 (en) | 2017-04-25 | 2018-12-25 | Omniome, Inc. | Methods and apparatus that increase sequencing-by-binding efficiency |
| AU2019217824A1 (en) | 2018-02-06 | 2020-07-30 | Omniome, Inc. | Compositions and techniques for nucleic acid primer extension |
| US10851131B2 (en) | 2018-02-16 | 2020-12-01 | Illumina, Inc. | Charge-tagged nucleotides and methods of use thereof |
| WO2019161253A1 (en) | 2018-02-16 | 2019-08-22 | Ultima Genomics, Inc. | Methods for sequencing with single frequency detection |
| US10400272B1 (en) | 2018-04-26 | 2019-09-03 | Omniome, Inc. | Methods and compositions for stabilizing nucleic acid-nucleotide-polymerase complexes |
| US11180794B2 (en) | 2018-05-31 | 2021-11-23 | Omniome, Inc. | Methods and compositions for capping nucleic acids |
| EP3802874A1 (en) | 2018-05-31 | 2021-04-14 | Omniome, Inc. | Increased signal to noise in nucleic acid sequencing |
| EP3827097A1 (en) * | 2018-07-24 | 2021-06-02 | Omniome, Inc. | Serial formation of ternary complex species |
| US10704094B1 (en) | 2018-11-14 | 2020-07-07 | Element Biosciences, Inc. | Multipart reagents having increased avidity for polymerase binding |
| US10876148B2 (en) | 2018-11-14 | 2020-12-29 | Element Biosciences, Inc. | De novo surface preparation and uses thereof |
| US10768173B1 (en) | 2019-09-06 | 2020-09-08 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| CN109610011A (zh) * | 2018-12-28 | 2019-04-12 | 厦门胜芨科技有限公司 | 一种NanoDNA超长伴随建库试剂盒及其使用方法 |
| US11499189B2 (en) | 2019-02-14 | 2022-11-15 | Pacific Biosciences Of California, Inc. | Mitigating adverse impacts of detection systems on nucleic acids and other biological analytes |
| EP3696170A1 (en) | 2019-02-15 | 2020-08-19 | Centre National De La Recherche Scientifique | 3,6-disubstituted-2-pyridinaldoxime scaffolds |
| EP3947659A4 (en) * | 2019-04-02 | 2022-12-28 | The Trustees of Columbia University in the City of New York | SEQUENCING BY ENERGY TRANSFER DYE PAIR SYNTHESIS |
| US11287422B2 (en) | 2019-09-23 | 2022-03-29 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| WO2021158750A1 (en) * | 2020-02-06 | 2021-08-12 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Automated lipid exchange-mass spectrometry systems and methods |
| WO2022006081A1 (en) * | 2020-06-30 | 2022-01-06 | Illumina, Inc. | Catalytically controlled sequencing by synthesis to produce scarless dna |
| WO2022232308A1 (en) | 2021-04-27 | 2022-11-03 | Singular Genomics Systems, Inc. | High density sequencing and multiplexed priming |
| WO2023172665A2 (en) | 2022-03-10 | 2023-09-14 | Singular Genomics Systems, Inc. | Nucleic acid delivery scaffolds |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2044616A1 (en) | 1989-10-26 | 1991-04-27 | Roger Y. Tsien | Dna sequencing |
| CA2415897A1 (en) | 2000-07-07 | 2002-01-17 | Susan H. Hardin | Real-time sequence determination |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| US7414116B2 (en) | 2002-08-23 | 2008-08-19 | Illumina Cambridge Limited | Labelled nucleotides |
| US8071755B2 (en) | 2004-05-25 | 2011-12-06 | Helicos Biosciences Corporation | Nucleotide analogs |
| US7264934B2 (en) * | 2004-06-10 | 2007-09-04 | Ge Healthcare Bio-Sciences Corp. | Rapid parallel nucleic acid analysis |
| DE602005020011D1 (de) | 2004-06-10 | 2010-04-29 | Ge Healthcare Bio Sciences | Verfahren zur nukleinsäureanalyse |
| US7482120B2 (en) | 2005-01-28 | 2009-01-27 | Helicos Biosciences Corporation | Methods and compositions for improving fidelity in a nucleic acid synthesis reaction |
| US7544794B1 (en) | 2005-03-11 | 2009-06-09 | Steven Albert Benner | Method for sequencing DNA and RNA by synthesis |
| WO2007075967A2 (en) | 2005-12-21 | 2007-07-05 | Roche Diagnostics Gmbh | Sequencing and genotyping using reversibly 2'-modified nucleotides |
| US8241573B2 (en) | 2006-03-31 | 2012-08-14 | Illumina, Inc. | Systems and devices for sequence by synthesis analysis |
| US7678894B2 (en) | 2007-05-18 | 2010-03-16 | Helicos Biosciences Corporation | Nucleotide analogs |
| JP5667049B2 (ja) | 2008-06-25 | 2015-02-12 | ライフ テクノロジーズ コーポレーション | 大規模なｆｅｔアレイを用いて分析物を測定するための方法および装置 |
| WO2010075188A2 (en) | 2008-12-23 | 2010-07-01 | Illumina Inc. | Multibase delivery for long reads in sequencing by synthesis protocols |
| US8034923B1 (en) | 2009-03-27 | 2011-10-11 | Steven Albert Benner | Reagents for reversibly terminating primer extension |
| AU2010245304B2 (en) * | 2009-04-27 | 2015-06-04 | Pacific Biosciences Of California, Inc. | Real-time sequencing methods and systems |
| WO2010141390A2 (en) * | 2009-06-05 | 2010-12-09 | Life Technologies Corporation | Nucleotide transient binding for sequencing methods |
| US8785132B2 (en) * | 2010-04-23 | 2014-07-22 | Postech Academy-Industry Foundation | Aptamer sandwich assays |
| AU2012308518B2 (en) | 2011-09-13 | 2017-08-17 | Agilent Technologies, Inc. | 5-methoxy, 3'-oh unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing |
| US8808989B1 (en) | 2013-04-02 | 2014-08-19 | Molecular Assemblies, Inc. | Methods and apparatus for synthesizing nucleic acids |
| CN107849605B (zh) | 2015-07-21 | 2021-08-20 | 欧姆尼欧美公司 | 核酸测序方法和系统 |
| US10077470B2 (en) | 2015-07-21 | 2018-09-18 | Omniome, Inc. | Nucleic acid sequencing methods and systems |
| SG11201807069XA (en) | 2016-04-22 | 2018-09-27 | Omniome Inc | Nucleic acid sequencing method and system employing enhanced detection of nucleotide-specific ternary complex formation |
| JP6828140B2 (ja) * | 2016-08-15 | 2021-02-10 | オムニオム インコーポレイテッドＯｍｎｉｏｍｅ， Ｉｎｃ． | 核酸をシーケンシングするための方法及びシステム |
| US9951385B1 (en) * | 2017-04-25 | 2018-04-24 | Omniome, Inc. | Methods and apparatus that increase sequencing-by-binding efficiency |
-
2017
- 2017-04-21 SG SG11201807069XA patent/SG11201807069XA/en unknown
- 2017-04-21 CA CA3011635A patent/CA3011635C/en active Active
- 2017-04-21 CN CN201780014376.XA patent/CN109072297B/zh active Active
- 2017-04-21 US US16/078,261 patent/US10982264B2/en active Active
- 2017-04-21 KR KR1020207019335A patent/KR102254451B1/ko active IP Right Grant
- 2017-04-21 EP EP17720996.2A patent/EP3445870B1/en active Active
- 2017-04-21 KR KR1020187024354A patent/KR20180099903A/ko not_active IP Right Cessation
- 2017-04-21 AU AU2017254688A patent/AU2017254688B2/en active Active
- 2017-04-21 WO PCT/US2017/028878 patent/WO2017184996A1/en active Application Filing
- 2017-04-21 JP JP2018538766A patent/JP2019512209A/ja active Pending
-
2021
- 2021-03-11 US US17/199,061 patent/US20210340600A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA3011635A1 (en) | 2017-10-26 |
| KR20180099903A (ko) | 2018-09-05 |
| CA3011635C (en) | 2021-10-26 |
| EP3445870A1 (en) | 2019-02-27 |
| WO2017184996A1 (en) | 2017-10-26 |
| JP2019512209A (ja) | 2019-05-16 |
| CN109072297B (zh) | 2022-09-13 |
| KR20200084922A (ko) | 2020-07-13 |
| KR102254451B1 (ko) | 2021-05-20 |
| CN109072297A (zh) | 2018-12-21 |
| US10982264B2 (en) | 2021-04-20 |
| US20210340600A1 (en) | 2021-11-04 |
| AU2017254688B2 (en) | 2020-05-14 |
| EP3445870B1 (en) | 2022-09-07 |
| US20190048404A1 (en) | 2019-02-14 |
| AU2017254688A1 (en) | 2018-08-02 |
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