SG11201807069XA - Nucleic acid sequencing method and system employing enhanced detection of nucleotide-specific ternary complex formation - Google Patents
Nucleic acid sequencing method and system employing enhanced detection of nucleotide-specific ternary complex formationInfo
- Publication number
- SG11201807069XA SG11201807069XA SG11201807069XA SG11201807069XA SG11201807069XA SG 11201807069X A SG11201807069X A SG 11201807069XA SG 11201807069X A SG11201807069X A SG 11201807069XA SG 11201807069X A SG11201807069X A SG 11201807069XA SG 11201807069X A SG11201807069X A SG 11201807069XA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- nucleotide
- nucleic acid
- rule
- applicant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/10—Nucleotidyl transfering
- C12Q2521/101—DNA polymerase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/113—Time
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/137—Concentration of a component of medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2533/00—Reactions characterised by the enzymatic reaction principle used
- C12Q2533/10—Reactions characterised by the enzymatic reaction principle used the purpose being to increase the length of an oligonucleotide strand
- C12Q2533/101—Primer extension
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662326356P | 2016-04-22 | 2016-04-22 | |
| PCT/US2017/028878 WO2017184996A1 (en) | 2016-04-22 | 2017-04-21 | Nucleic acid sequencing method and system employing enhanced detection of nucleotide-specific ternary complex formation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201807069XA true SG11201807069XA (en) | 2018-09-27 |
Family
ID=58664858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201807069XA SG11201807069XA (en) | 2016-04-22 | 2017-04-21 | Nucleic acid sequencing method and system employing enhanced detection of nucleotide-specific ternary complex formation |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10982264B2 (ko) |
| EP (1) | EP3445870B1 (ko) |
| JP (1) | JP2019512209A (ko) |
| KR (2) | KR20180099903A (ko) |
| CN (1) | CN109072297B (ko) |
| AU (1) | AU2017254688B2 (ko) |
| CA (1) | CA3011635C (ko) |
| SG (1) | SG11201807069XA (ko) |
| WO (1) | WO2017184996A1 (ko) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019512209A (ja) | 2016-04-22 | 2019-05-16 | オムニオム インコーポレイテッドＯｍｎｉｏｍｅ， Ｉｎｃ． | ヌクレオチド特異的三元複合体形成の増強された検出を利用した核酸配列決定方法及びシステム |
| EP3449012B1 (en) | 2016-04-29 | 2020-12-23 | Omniome, Inc. | Sequencing method employing ternary complex destabilization to identify cognate nucleotides |
| WO2018034780A1 (en) | 2016-08-15 | 2018-02-22 | Omniome, Inc. | Sequencing method for rapid identification and processing of cognate nucleotide pairs |
| AU2017313718B2 (en) * | 2016-08-15 | 2023-09-14 | Pacific Biosciences Of California, Inc. | Method and system for sequencing nucleic acids |
| US11248254B2 (en) | 2016-12-30 | 2022-02-15 | Omniome, Inc. | Method and system employing distinguishable polymerases for detecting ternary complexes and identifying cognate nucleotides |
| US10161003B2 (en) | 2017-04-25 | 2018-12-25 | Omniome, Inc. | Methods and apparatus that increase sequencing-by-binding efficiency |
| EP3749777A4 (en) * | 2018-02-06 | 2021-11-24 | Omniome, Inc. | COMPOSITIONS AND TECHNIQUES FOR NUCLEIC ACID PRIMER EXTENSION |
| KR102430323B1 (ko) | 2018-02-16 | 2022-08-08 | 일루미나, 인코포레이티드 | 전하-태그 뉴클레오타이드 및 이의 사용 방법 |
| WO2019161253A1 (en) | 2018-02-16 | 2019-08-22 | Ultima Genomics, Inc. | Methods for sequencing with single frequency detection |
| CA3098296A1 (en) | 2018-04-26 | 2019-10-31 | Omniome, Inc. | Methods and compositions for stabilizing nucleic acid-nucleotide-polymerase complexes |
| US11180794B2 (en) | 2018-05-31 | 2021-11-23 | Omniome, Inc. | Methods and compositions for capping nucleic acids |
| EP3802874A1 (en) | 2018-05-31 | 2021-04-14 | Omniome, Inc. | Increased signal to noise in nucleic acid sequencing |
| AU2019312152A1 (en) | 2018-07-24 | 2021-02-18 | Pacific Biosciences Of California, Inc. | Serial formation of ternary complex species |
| US10704094B1 (en) | 2018-11-14 | 2020-07-07 | Element Biosciences, Inc. | Multipart reagents having increased avidity for polymerase binding |
| US10768173B1 (en) | 2019-09-06 | 2020-09-08 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| US10876148B2 (en) | 2018-11-14 | 2020-12-29 | Element Biosciences, Inc. | De novo surface preparation and uses thereof |
| CN109610011A (zh) * | 2018-12-28 | 2019-04-12 | 厦门胜芨科技有限公司 | 一种NanoDNA超长伴随建库试剂盒及其使用方法 |
| EP3924513B1 (en) * | 2019-02-14 | 2023-04-12 | Pacific Biosciences of California, Inc. | Mitigating adverse impacts of detection systems on nucleic acids and other biological analytes |
| EP3696170A1 (en) | 2019-02-15 | 2020-08-19 | Centre National De La Recherche Scientifique | 3,6-disubstituted-2-pyridinaldoxime scaffolds |
| US20220213542A1 (en) * | 2019-04-02 | 2022-07-07 | The Trustees Of Columbia University In The City Of New York | Sequencing by synthesis with energy transfer dye pairs |
| US11287422B2 (en) | 2019-09-23 | 2022-03-29 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| WO2021158750A1 (en) * | 2020-02-06 | 2021-08-12 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Automated lipid exchange-mass spectrometry systems and methods |
| KR20230037503A (ko) * | 2020-06-30 | 2023-03-16 | 일루미나, 인코포레이티드 | 무흔적 dna를 생성하기 위한 촉매적으로 제어된 합성에 의한 서열분석 |
| US11578320B2 (en) | 2021-04-27 | 2023-02-14 | Singular Genomics Systems, Inc. | High density sequencing and multiplexed priming |
| WO2023172665A2 (en) | 2022-03-10 | 2023-09-14 | Singular Genomics Systems, Inc. | Nucleic acid delivery scaffolds |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2044616A1 (en) | 1989-10-26 | 1991-04-27 | Roger Y. Tsien | Dna sequencing |
| EP1368460B1 (en) | 2000-07-07 | 2007-10-31 | Visigen Biotechnologies, Inc. | Real-time sequence determination |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| US7414116B2 (en) | 2002-08-23 | 2008-08-19 | Illumina Cambridge Limited | Labelled nucleotides |
| US8071755B2 (en) | 2004-05-25 | 2011-12-06 | Helicos Biosciences Corporation | Nucleotide analogs |
| US7264934B2 (en) * | 2004-06-10 | 2007-09-04 | Ge Healthcare Bio-Sciences Corp. | Rapid parallel nucleic acid analysis |
| CN101120098A (zh) | 2004-06-10 | 2008-02-06 | 通用电气医疗集团生物科学公司 | 核酸分析方法 |
| US7482120B2 (en) | 2005-01-28 | 2009-01-27 | Helicos Biosciences Corporation | Methods and compositions for improving fidelity in a nucleic acid synthesis reaction |
| US7544794B1 (en) | 2005-03-11 | 2009-06-09 | Steven Albert Benner | Method for sequencing DNA and RNA by synthesis |
| WO2007075967A2 (en) | 2005-12-21 | 2007-07-05 | Roche Diagnostics Gmbh | Sequencing and genotyping using reversibly 2'-modified nucleotides |
| SG170802A1 (en) | 2006-03-31 | 2011-05-30 | Solexa Inc | Systems and devices for sequence by synthesis analysis |
| US7678894B2 (en) | 2007-05-18 | 2010-03-16 | Helicos Biosciences Corporation | Nucleotide analogs |
| US8470164B2 (en) * | 2008-06-25 | 2013-06-25 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| WO2010075188A2 (en) | 2008-12-23 | 2010-07-01 | Illumina Inc. | Multibase delivery for long reads in sequencing by synthesis protocols |
| US8034923B1 (en) | 2009-03-27 | 2011-10-11 | Steven Albert Benner | Reagents for reversibly terminating primer extension |
| EP2425023B1 (en) * | 2009-04-27 | 2015-12-23 | Pacific Biosciences of California, Inc. | Real-time sequencing methods and systems |
| WO2010141391A2 (en) * | 2009-06-05 | 2010-12-09 | Life Technologies Corporation | Mutant dna polymerases |
| US8785132B2 (en) | 2010-04-23 | 2014-07-22 | Postech Academy-Industry Foundation | Aptamer sandwich assays |
| KR102048274B1 (ko) | 2011-09-13 | 2019-11-25 | 애질런트 테크놀로지스, 인크. | 핵산 시퀀싱을 위하여 5-메톡시, 3'-oh 차단안된, 신속하게 광절단가능한 종료 뉴클레오티드 및 핵산 시퀀싱 방법 |
| US8808989B1 (en) | 2013-04-02 | 2014-08-19 | Molecular Assemblies, Inc. | Methods and apparatus for synthesizing nucleic acids |
| CN107849605B (zh) | 2015-07-21 | 2021-08-20 | 欧姆尼欧美公司 | 核酸测序方法和系统 |
| US10077470B2 (en) | 2015-07-21 | 2018-09-18 | Omniome, Inc. | Nucleic acid sequencing methods and systems |
| JP2019512209A (ja) | 2016-04-22 | 2019-05-16 | オムニオム インコーポレイテッドＯｍｎｉｏｍｅ， Ｉｎｃ． | ヌクレオチド特異的三元複合体形成の増強された検出を利用した核酸配列決定方法及びシステム |
| AU2017313718B2 (en) * | 2016-08-15 | 2023-09-14 | Pacific Biosciences Of California, Inc. | Method and system for sequencing nucleic acids |
| US9951385B1 (en) * | 2017-04-25 | 2018-04-24 | Omniome, Inc. | Methods and apparatus that increase sequencing-by-binding efficiency |
-
2017
- 2017-04-21 JP JP2018538766A patent/JP2019512209A/ja active Pending
- 2017-04-21 WO PCT/US2017/028878 patent/WO2017184996A1/en active Application Filing
- 2017-04-21 KR KR1020187024354A patent/KR20180099903A/ko not_active IP Right Cessation
- 2017-04-21 CN CN201780014376.XA patent/CN109072297B/zh active Active
- 2017-04-21 US US16/078,261 patent/US10982264B2/en active Active
- 2017-04-21 SG SG11201807069XA patent/SG11201807069XA/en unknown
- 2017-04-21 CA CA3011635A patent/CA3011635C/en active Active
- 2017-04-21 EP EP17720996.2A patent/EP3445870B1/en active Active
- 2017-04-21 KR KR1020207019335A patent/KR102254451B1/ko active IP Right Grant
- 2017-04-21 AU AU2017254688A patent/AU2017254688B2/en active Active
-
2021
- 2021-03-11 US US17/199,061 patent/US20210340600A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US10982264B2 (en) | 2021-04-20 |
| EP3445870B1 (en) | 2022-09-07 |
| KR20180099903A (ko) | 2018-09-05 |
| CN109072297B (zh) | 2022-09-13 |
| CA3011635A1 (en) | 2017-10-26 |
| KR20200084922A (ko) | 2020-07-13 |
| AU2017254688B2 (en) | 2020-05-14 |
| US20190048404A1 (en) | 2019-02-14 |
| EP3445870A1 (en) | 2019-02-27 |
| CA3011635C (en) | 2021-10-26 |
| US20210340600A1 (en) | 2021-11-04 |
| KR102254451B1 (ko) | 2021-05-20 |
| WO2017184996A1 (en) | 2017-10-26 |
| CN109072297A (zh) | 2018-12-21 |
| JP2019512209A (ja) | 2019-05-16 |
| AU2017254688A1 (en) | 2018-08-02 |
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