SG11201805828YA - Method of treating c3 glomerulopathy - Google Patents
Method of treating c3 glomerulopathyInfo
- Publication number
- SG11201805828YA SG11201805828YA SG11201805828YA SG11201805828YA SG11201805828YA SG 11201805828Y A SG11201805828Y A SG 11201805828YA SG 11201805828Y A SG11201805828Y A SG 11201805828YA SG 11201805828Y A SG11201805828Y A SG 11201805828YA SG 11201805828Y A SG11201805828Y A SG 11201805828YA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- january
- pct
- months
- glomerulopathy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662278788P | 2016-01-14 | 2016-01-14 | |
| US201662280346P | 2016-01-19 | 2016-01-19 | |
| US201662347450P | 2016-06-08 | 2016-06-08 | |
| US201662397527P | 2016-09-21 | 2016-09-21 | |
| PCT/US2017/013132 WO2017123716A1 (en) | 2016-01-14 | 2017-01-12 | Method of treating c3 glomerulopathy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201805828YA true SG11201805828YA (en) | 2018-08-30 |
Family
ID=59312069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201805828YA SG11201805828YA (en) | 2016-01-14 | 2017-01-12 | Method of treating c3 glomerulopathy |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US20170202821A1 (es) |
| EP (1) | EP3402486A4 (es) |
| JP (3) | JP7339733B2 (es) |
| KR (1) | KR20180102642A (es) |
| CN (1) | CN108601790A (es) |
| AU (1) | AU2017207359C1 (es) |
| BR (2) | BR122024002810A2 (es) |
| CA (1) | CA3010735C (es) |
| IL (1) | IL260539B (es) |
| MA (1) | MA43872A (es) |
| MX (2) | MX2018008624A (es) |
| NZ (1) | NZ744083A (es) |
| RU (1) | RU2742888C2 (es) |
| SG (1) | SG11201805828YA (es) |
| TW (1) | TWI791423B (es) |
| WO (1) | WO2017123716A1 (es) |
| ZA (1) | ZA201804513B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010075257A1 (en) | 2008-12-22 | 2010-07-01 | Chemocentryx, Inc. | C5ar antagonists |
| PL2585064T3 (pl) | 2010-06-24 | 2017-09-29 | Chemocentryx, Inc. | Antagoniści C5AR |
| ES2926828T3 (es) | 2014-09-29 | 2022-10-28 | Chemocentryx Inc | Procesos e intermedios en la preparación de antagonistas de C5aR |
| WO2017035401A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amide compounds for treatment of immune and inflammatory disorders |
| WO2017035405A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amino compounds for treatment of immune and inflammatory disorders |
| TWI791423B (zh) | 2016-01-14 | 2023-02-11 | 美商卡默森屈有限公司 | C3腎絲球病變之治療方法 |
| AU2018227849B2 (en) | 2017-03-01 | 2022-04-28 | Achillion Pharmaceuticals, Inc. | Aryl, heteroary, and heterocyclic pharmaceutical compounds for treatment of medical disorders |
| WO2018160891A1 (en) | 2017-03-01 | 2018-09-07 | Achillion Pharmaceutical, Inc. | Pharmaceutical compounds for treatment of medical disorders |
| EP3658657A1 (en) * | 2017-07-27 | 2020-06-03 | Procter & Gamble International Operations SA. | Phase-stable, sprayable freshening compositions comprising suspended particles |
| WO2019227102A1 (en) * | 2018-05-25 | 2019-11-28 | Achillion Pharmaceuticals, Inc. | Complement alternative pathway-associated nephropathy biomarkers |
| US11814363B2 (en) | 2018-09-06 | 2023-11-14 | Achillion Pharmaceuticals, Inc. | Morphic forms of danicopan |
| JP7443375B2 (ja) | 2018-09-06 | 2024-03-05 | アキリオン ファーマシューティカルズ， インコーポレーテッド | 医学的障害の治療のための大環状化合物 |
| US11807627B2 (en) | 2018-09-25 | 2023-11-07 | Achillon Pharmaceuticals, Inc. | Morphic forms of complement factor D inhibitors |
| MD3886820T2 (ro) | 2018-11-30 | 2023-07-31 | Chemocentryx Inc | Formulări de capsule |
| MX2023001504A (es) * | 2020-08-07 | 2023-04-27 | Kira Pharmaceuticals Suzhou Ltd | Compuestos como inhibidores del receptor del componente complemento 5a (c5ar). |
| MX2023007420A (es) * | 2020-12-21 | 2023-06-29 | Chemocentryx Inc | Tratamiento de glomerulopatia c3 usando un inhibidor de c5a. |
| CN115192563B (zh) * | 2022-05-09 | 2023-10-13 | 北京大学第一医院 | C3a/C3aR通路拮抗剂治疗原发性膜性肾病的用途 |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1268002A (en) | 1917-09-12 | 1918-05-28 | William M Goodwin | Measuring instrument. |
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US4686100A (en) | 1985-04-02 | 1987-08-11 | The Board Of Trustees Of The Leland Stanford Junior University | Method for the treatment of adult respiratory distress syndrome |
| CN1261098C (zh) | 1998-08-28 | 2006-06-28 | 西奥斯股份有限公司 | p38－α激酶的抑制剂 |
| RU2197288C2 (ru) * | 1999-08-03 | 2003-01-27 | Тверская медицинская академия | Способ лечения больных хроническим гломерулонефритом |
| JP2003532726A (ja) | 2000-05-05 | 2003-11-05 | スミスクライン・ビーチャム・コーポレイション | 新規抗感染症薬 |
| ATE485266T1 (de) | 2000-08-10 | 2010-11-15 | Mitsubishi Tanabe Pharma Corp | 3-substituierte harnstoffderivate und deren medizinische verwendung |
| EP1318140B9 (en) | 2000-09-14 | 2014-05-21 | Mitsubishi Tanabe Pharma Corporation | Novel amide derivatives and medicinal use thereof |
| JP5260818B2 (ja) | 2000-09-29 | 2013-08-14 | ノバルティス・インターナショナル・ファーマシューティカル・リミテッド | 高親和性低分子Ｃ５ａ受容体調節物質 |
| MX342385B (es) | 2001-08-17 | 2016-09-27 | Genentech Inc | Inhibidores de la ruta del complemento que se unen a c5 y c5a sin evitar la formación de c5b. |
| US7427615B2 (en) | 2001-09-21 | 2008-09-23 | Mitsubishi Pharma Corporation | 3-substituted-4-pyrimidone derivatives |
| ITMI20012025A1 (it) | 2001-09-28 | 2003-03-28 | Dompe Spa | Sali di ammonio quaternari di omega-amminoalchilammidi di acidi r 2-aril-propionici e composizioni farmaceutiche che li contengono |
| US20030195192A1 (en) | 2002-04-05 | 2003-10-16 | Fortuna Haviv | Nicotinamides having antiangiogenic activity |
| EP1487796A4 (en) | 2002-03-28 | 2005-11-16 | Neurogen Corp | SUBSTITUTED BIARYLAMIDES AS MODULATORS OF THE C5A RECEPTOR |
| EP1487798A4 (en) | 2002-03-28 | 2005-07-13 | Neurogen Corp | Substituted tetrahydroisoquinolines as C5A receptor modulators |
| WO2003084524A1 (en) | 2002-03-29 | 2003-10-16 | Neurogen Corporation | Combination therapy for the treatment of conditions with pathogenic inflammatory components |
| US20040014744A1 (en) | 2002-04-05 | 2004-01-22 | Fortuna Haviv | Substituted pyridines having antiangiogenic activity |
| US7138420B2 (en) | 2002-08-08 | 2006-11-21 | Boehringer Ingelheim Pharmaceuticals Inc. | Substituted benzimidazole compounds |
| AU2003265625A1 (en) | 2002-08-21 | 2004-03-11 | Neurogen Corporation | Amino methyl imidazoles as c5a receptor modulators |
| WO2004043223A2 (en) | 2002-11-05 | 2004-05-27 | The Regents Of The University Of Michigan | Compositions and methods for the diagnosis and treatment of sepsis |
| FR2846654A1 (fr) | 2002-11-05 | 2004-05-07 | Servier Lab | Nouveaux derives de la 2,3-dihydro-4(1h)-pyridinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2504941C (en) | 2002-11-08 | 2012-06-26 | Neurogen Corporation | 3-substituted-6-aryl pyridines |
| AU2003902354A0 (en) | 2003-05-15 | 2003-05-29 | Harkin, Denis W. | Treatment of haemorrhagic shock |
| WO2004110996A1 (en) | 2003-06-19 | 2004-12-23 | Pfizer Products Inc. | Nk1 antagonist |
| US20060154917A1 (en) | 2003-07-03 | 2006-07-13 | Neurogen Corporation | Substituted (heterocycloalkyl)methyl azole derivatives as c5a receptor modulators |
| GB0325956D0 (en) | 2003-11-06 | 2003-12-10 | Addex Pharmaceuticals Sa | Novel compounds |
| EP1758580A4 (en) | 2004-06-24 | 2008-01-16 | Incyte Corp | N-SUBSTITUTED PIPERIDINE AND ITS USE AS A MEDICAMENT |
| US7635698B2 (en) | 2004-12-29 | 2009-12-22 | Millennium Pharmaceuticals, Inc. | Compounds useful as chemokine receptor antagonists |
| CN101163693B (zh) | 2005-02-18 | 2013-03-06 | 阿斯利康(瑞典)有限公司 | 抗菌哌啶衍生物 |
| WO2007035428A1 (en) | 2005-09-15 | 2007-03-29 | Bristol-Myers Squibb Company | Met kinase inhibitors |
| US20070112015A1 (en) | 2005-10-28 | 2007-05-17 | Chemocentryx, Inc. | Substituted dihydropyridines and methods of use |
| RS55192B1 (sr) | 2005-11-24 | 2017-01-31 | Dompé Farm S P A | Derivati (r)-arilkilamina i farmaceutske kompozicije koje ih sadrže |
| DK2359834T5 (en) * | 2006-03-15 | 2017-02-06 | Alexion Pharma Inc | Treatment of paroxysmal nocturnal hemoglobinuria patients with a complement inhibitor |
| WO2008022060A2 (en) | 2006-08-14 | 2008-02-21 | Novartis Ag | Imidazo-pyridine derivatives for modulating protein kinase activity |
| EP2077842A2 (en) * | 2006-10-31 | 2009-07-15 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of an egfr antagonist for the treatment of glomerolonephritis |
| MX2009013775A (es) | 2007-06-29 | 2010-04-12 | Torrent Pharmaceuticals Ltd | Sustituto novedoso de piperidones sustituidas como inductor de hsp. |
| US9284297B2 (en) | 2008-08-11 | 2016-03-15 | President And Fellows Of Harvard College | Halofuginone analogs for inhibition of tRNA synthetases and uses thereof |
| AU2009290137A1 (en) | 2008-09-03 | 2010-03-11 | Xenome Ltd | Libraries of peptide conjugates and methods for making them |
| US20100074863A1 (en) | 2008-09-17 | 2010-03-25 | Yat Sun Or | Anti-infective pyrrolidine derivatives and analogs |
| SI2894165T1 (sl) | 2008-11-10 | 2023-04-28 | Alexion Pharmaceuticals, Inc. | Postopki in sestavki za zdravljenje motenj povezanih s komplementom |
| US20110275639A1 (en) | 2008-12-22 | 2011-11-10 | Chemocentryx, Inc. | C5aR ANTAGONISTS |
| WO2010075257A1 (en) | 2008-12-22 | 2010-07-01 | Chemocentryx, Inc. | C5ar antagonists |
| WO2011035143A2 (en) | 2009-09-17 | 2011-03-24 | The Regents Of The University Of Michigan | Methods and compositions for inhibiting rho-mediated diseases and conditions |
| PL2585064T3 (pl) | 2010-06-24 | 2017-09-29 | Chemocentryx, Inc. | Antagoniści C5AR |
| US8147400B1 (en) * | 2011-01-17 | 2012-04-03 | Coloplast A/S | Penile implant with dilatant liquid |
| EA201590053A1 (ru) * | 2012-06-20 | 2015-08-31 | Новартис Аг | Модуляторы пути системы комплемента и их применение |
| DK2994488T3 (da) | 2013-05-08 | 2022-10-03 | Novo Nordisk As | Anvendelse af c5ar-antagonister |
| ES2926828T3 (es) | 2014-09-29 | 2022-10-28 | Chemocentryx Inc | Procesos e intermedios en la preparación de antagonistas de C5aR |
| TWI791423B (zh) | 2016-01-14 | 2023-02-11 | 美商卡默森屈有限公司 | C3腎絲球病變之治療方法 |
| CN109310686B (zh) | 2016-04-04 | 2022-06-21 | 凯莫森特里克斯股份有限公司 | 可溶性C5aR拮抗剂 |
| MX2023007420A (es) | 2020-12-21 | 2023-06-29 | Chemocentryx Inc | Tratamiento de glomerulopatia c3 usando un inhibidor de c5a. |
-
2017
- 2017-01-12 TW TW106100938A patent/TWI791423B/zh active
- 2017-01-12 MX MX2018008624A patent/MX2018008624A/es unknown
- 2017-01-12 US US15/404,610 patent/US20170202821A1/en not_active Abandoned
- 2017-01-12 CA CA3010735A patent/CA3010735C/en active Active
- 2017-01-12 RU RU2018129378A patent/RU2742888C2/ru active
- 2017-01-12 SG SG11201805828YA patent/SG11201805828YA/en unknown
- 2017-01-12 MA MA043872A patent/MA43872A/fr unknown
- 2017-01-12 BR BR122024002810-7A patent/BR122024002810A2/pt unknown
- 2017-01-12 EP EP17738902.0A patent/EP3402486A4/en active Pending
- 2017-01-12 MX MX2022006069A patent/MX2022006069A/es unknown
- 2017-01-12 AU AU2017207359A patent/AU2017207359C1/en active Active
- 2017-01-12 WO PCT/US2017/013132 patent/WO2017123716A1/en active Application Filing
- 2017-01-12 CN CN201780006962.XA patent/CN108601790A/zh active Pending
- 2017-01-12 NZ NZ744083A patent/NZ744083A/en unknown
- 2017-01-12 KR KR1020187023360A patent/KR20180102642A/ko active Search and Examination
- 2017-01-12 JP JP2018536408A patent/JP7339733B2/ja active Active
- 2017-01-12 BR BR112018014222-0A patent/BR112018014222A2/pt active Search and Examination
-
2018
- 2018-07-06 ZA ZA2018/04513A patent/ZA201804513B/en unknown
- 2018-07-11 IL IL260539A patent/IL260539B/en active IP Right Grant
- 2018-11-08 US US16/184,535 patent/US11285138B2/en active Active
-
2021
- 2021-08-06 JP JP2021129774A patent/JP2021183625A/ja active Pending
-
2022
- 2022-02-14 US US17/670,604 patent/US11779576B2/en active Active
-
2023
- 2023-06-20 JP JP2023100664A patent/JP2023126235A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR122024002810A2 (pt) | 2024-03-12 |
| CA3010735C (en) | 2023-06-13 |
| MA43872A (fr) | 2021-05-19 |
| ZA201804513B (en) | 2024-01-31 |
| TWI791423B (zh) | 2023-02-11 |
| AU2017207359C1 (en) | 2022-09-01 |
| JP2023126235A (ja) | 2023-09-07 |
| BR112018014222A2 (pt) | 2018-12-11 |
| JP2019501935A (ja) | 2019-01-24 |
| US20220354837A1 (en) | 2022-11-10 |
| RU2742888C2 (ru) | 2021-02-11 |
| MX2018008624A (es) | 2018-12-10 |
| NZ744083A (en) | 2022-07-01 |
| CN108601790A (zh) | 2018-09-28 |
| JP2021183625A (ja) | 2021-12-02 |
| RU2018129378A3 (es) | 2020-05-20 |
| MX2022006069A (es) | 2023-01-12 |
| WO2017123716A1 (en) | 2017-07-20 |
| RU2018129378A (ru) | 2020-02-14 |
| US20190201388A1 (en) | 2019-07-04 |
| US11285138B2 (en) | 2022-03-29 |
| EP3402486A4 (en) | 2019-08-28 |
| AU2017207359B2 (en) | 2022-04-14 |
| TW201726134A (zh) | 2017-08-01 |
| US20170202821A1 (en) | 2017-07-20 |
| AU2017207359A1 (en) | 2018-07-26 |
| EP3402486A1 (en) | 2018-11-21 |
| US11779576B2 (en) | 2023-10-10 |
| CA3010735A1 (en) | 2017-07-20 |
| IL260539B (en) | 2021-05-31 |
| JP7339733B2 (ja) | 2023-09-06 |
| KR20180102642A (ko) | 2018-09-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG11201805828YA (en) | Method of treating c3 glomerulopathy | |
| SG11201906431UA (en) | Method for the treatment of thromboembolism | |
| SG11201806322QA (en) | Maytansinoid derivatives, conjugates thereof, and methods of use | |
| SG11201909963YA (en) | Methods for treating dravet syndrome | |
| SG11201804901WA (en) | Compounds for the treatment of cancer and inflammatory disease | |
| SG11201903697WA (en) | Liver organoid compositions and methods of making and using same | |
| SG11201908971RA (en) | Erbb-2 and erbb3 binding bispecific antibodies for use in the treatment f cells that have an nrg1 fusion gene | |
| SG11201906885TA (en) | Methods for the administration of certain vmat2 inhibitors | |
| SG11201804647TA (en) | Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde | |
| SG11201805072PA (en) | Nicotine powder delivery system | |
| SG11201808125RA (en) | Methods for solid tumor treatment | |
| SG11201810951RA (en) | Receptor selective retinoid and rexinoid compounds and immune modulators for cancer immunotherapy | |
| SG11201808222RA (en) | Methods of treatment of cholestatic diseases | |
| SG11201807784SA (en) | 3-desoxy derivative and pharmaceutical compositions thereof | |
| SG11201805311XA (en) | Method of treating a mammal, including human, against cancer using methionine and asparagine depletion | |
| SG11201901996UA (en) | Formulations of ( r)-2-amino-3-phenylpropyl carbamate | |
| SG11201808525UA (en) | Anti-complement factor bb antibodies and uses thereof | |
| SG11201807041PA (en) | Improved preparations of adult liver progenitor cells | |
| SG11201805579SA (en) | Recombinant igg fc multimers | |
| SG11201810927QA (en) | Pd-l1-specific antibodies and methods of using the same | |
| SG11201804263PA (en) | Cancer treatment using 2-deoxy-2-fluoro-l-fucose in combination with a checkpoint inhibitor | |
| SG11201807593TA (en) | Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers | |
| SG11201807255YA (en) | Treatment of autoimmune diseases with combinations of rxr agonists and thyroid hormones | |
| SG11201809527UA (en) | Methods of treating circadian rhythm sleep disorders | |
| SG11201901063SA (en) | Therapeutic agents for neurodegenerative diseases |