DK2994488T3 - Anvendelse af c5ar-antagonister - Google Patents
Anvendelse af c5ar-antagonister Download PDFInfo
- Publication number
- DK2994488T3 DK2994488T3 DK14724691.2T DK14724691T DK2994488T3 DK 2994488 T3 DK2994488 T3 DK 2994488T3 DK 14724691 T DK14724691 T DK 14724691T DK 2994488 T3 DK2994488 T3 DK 2994488T3
- Authority
- DK
- Denmark
- Prior art keywords
- c5ar antagonists
- c5ar
- antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13166973 | 2013-05-08 | ||
US201361821336P | 2013-05-09 | 2013-05-09 | |
EP14151982 | 2014-01-21 | ||
PCT/EP2014/059477 WO2014180961A1 (en) | 2013-05-08 | 2014-05-08 | Use of c5ar antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2994488T3 true DK2994488T3 (da) | 2022-10-03 |
Family
ID=51866834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14724691.2T DK2994488T3 (da) | 2013-05-08 | 2014-05-08 | Anvendelse af c5ar-antagonister |
Country Status (6)
Country | Link |
---|---|
US (2) | US20160060351A1 (da) |
EP (1) | EP2994488B1 (da) |
JP (1) | JP2016523829A (da) |
CN (1) | CN105392803B (da) |
DK (1) | DK2994488T3 (da) |
WO (1) | WO2014180961A1 (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK3798230T3 (en) | 2011-06-06 | 2022-10-31 | Novo Nordisk As | Terapeutiske antistoffer |
CN113121415A (zh) | 2014-09-29 | 2021-07-16 | 凯莫森特里克斯股份有限公司 | 制备C5aR拮抗剂的方法和中间体 |
US20180243370A1 (en) | 2015-09-14 | 2018-08-30 | Children's Hospital Medical Center | Methods and compositions for treatment of gaucher disease via modulation of c5a receptor |
CN106957366B (zh) * | 2016-01-12 | 2022-02-01 | 上海昀怡健康科技发展有限公司 | 一种C5aR抗体及其制备方法和应用 |
BR112018014222A2 (pt) | 2016-01-14 | 2018-12-11 | Chemocentryx, Inc. | método de tratamento da glomerulopatia c3 |
US10376595B2 (en) | 2017-04-03 | 2019-08-13 | Inflarx Gmbh | Treatment of inflammatory diseases with inhibitors of C5a activity |
CA3066689C (en) * | 2017-06-23 | 2024-01-16 | Inflarx Gmbh | Treatment of inflammatory diseases with inhibitors of c5a activity |
SG11202108761YA (en) * | 2019-03-14 | 2021-09-29 | Morphosys Ag | Antibodies targeting c5ar |
TW202140553A (zh) | 2020-01-13 | 2021-11-01 | 美商威特拉公司 | C5ar1抗體分子及其用途 |
AU2021324314A1 (en) | 2020-08-12 | 2023-05-25 | Innate Pharma | Subcutaneous anti-c5ar antagonist treatment regimen with avdoralimab |
CN116635075A (zh) * | 2020-12-21 | 2023-08-22 | 坎莫森特里克斯公司 | 使用c5a抑制剂治疗c3肾小球病 |
EP4277931A1 (en) | 2021-01-13 | 2023-11-22 | Visterra, Inc. | Humanized complement 5a receptor 1 antibodies and methods of use thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4958387B2 (ja) * | 2001-08-17 | 2012-06-20 | ジェネンテック, インコーポレイテッド | C5bの形成を妨害することなくc5及びc5aに結合する補体経路阻害剤 |
NZ534399A (en) * | 2002-01-25 | 2008-08-29 | G2 Therapies Ltd | Monoclonal antibodies against extracellular loops of C5aR |
AU2002952086A0 (en) * | 2002-10-16 | 2002-11-07 | The University Of Queensland | Treatment of osteoarthritis |
US7807389B2 (en) * | 2003-03-14 | 2010-10-05 | University Of Rochester | Methods and compositions related to joint inflammation diseases |
WO2007055374A1 (ja) * | 2005-11-14 | 2007-05-18 | Mitsubishi Tanabe Pharma Corporation | 骨粗鬆症治療剤 |
US8268972B2 (en) * | 2008-02-20 | 2012-09-18 | G2 Inflammation Pty Ltd | Humanized anti-C5aR antibodies |
WO2009149081A1 (en) * | 2008-06-02 | 2009-12-10 | Novelmed Therapeutics, Inc. | Method for treating inflammatory conditions |
WO2009151634A1 (en) * | 2008-06-12 | 2009-12-17 | The Board Of Trustees Of The Leland Stanford Junior University | Complement inhibitory agents as therapeutics in posttraumatic and degenerative arthritis |
-
2014
- 2014-05-08 CN CN201480025887.8A patent/CN105392803B/zh active Active
- 2014-05-08 DK DK14724691.2T patent/DK2994488T3/da active
- 2014-05-08 WO PCT/EP2014/059477 patent/WO2014180961A1/en active Application Filing
- 2014-05-08 JP JP2016512383A patent/JP2016523829A/ja active Pending
- 2014-05-08 EP EP14724691.2A patent/EP2994488B1/en active Active
- 2014-05-08 US US14/888,141 patent/US20160060351A1/en not_active Abandoned
-
2019
- 2019-03-26 US US16/365,496 patent/US20200017598A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20200017598A1 (en) | 2020-01-16 |
EP2994488A1 (en) | 2016-03-16 |
WO2014180961A1 (en) | 2014-11-13 |
CN105392803A (zh) | 2016-03-09 |
CN105392803B (zh) | 2019-12-06 |
EP2994488B1 (en) | 2022-07-13 |
US20160060351A1 (en) | 2016-03-03 |
JP2016523829A (ja) | 2016-08-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK2970954T3 (da) | Modifikation af polypeptider | |
DK3587448T3 (da) | Heterodimere proteiner | |
DK3080100T3 (da) | Hæmmere af lysinspecifik demethylase-1 | |
DK2881868T3 (da) | Søgegrænseflade | |
DK2994488T3 (da) | Anvendelse af c5ar-antagonister | |
DK3010503T3 (da) | Hidtil ukendte bicykliske bromodomæne-inhibitorer | |
DK3342773T3 (da) | Syk-hæmmere | |
DK3027618T3 (da) | Polymorf af syk-hæmmere | |
DK3613453T3 (da) | Fordamper | |
DK2968208T3 (da) | Behandling af kataplexi | |
DK2961388T3 (da) | Kombinationer af lægemidler | |
DK2981255T3 (da) | Terapeutiske anvendelser af empagliflozin | |
DK3038654T3 (da) | Ny anvendelse | |
DK3077047T3 (da) | Aramcholsalte | |
DK3060460T3 (da) | Saddel | |
DK3027598T3 (da) | Oxoquinazolinyl-butanamidderivater | |
DK2956698T5 (da) | Bindestrimler | |
DK2965026T3 (da) | Generering af slushice | |
DK3052081T3 (da) | Pastil | |
DK2946640T3 (da) | Langmuir-probe | |
CL2014001444S1 (es) | Clip | |
DK3044389T3 (da) | Vinduespost-tværstykke-konstruktion | |
DK3071227T3 (da) | Fiskevaccine | |
DK2822301T3 (da) | Bestemmelse af individuelle HRTF | |
DE102013106534B8 (de) | Chromatographiepipettenspitze |