SG11201705312PA - Composition containing nucleic acid molecule stably - Google Patents
Composition containing nucleic acid molecule stablyInfo
- Publication number
- SG11201705312PA SG11201705312PA SG11201705312PA SG11201705312PA SG11201705312PA SG 11201705312P A SG11201705312P A SG 11201705312PA SG 11201705312P A SG11201705312P A SG 11201705312PA SG 11201705312P A SG11201705312P A SG 11201705312PA SG 11201705312P A SG11201705312P A SG 11201705312PA
- Authority
- SG
- Singapore
- Prior art keywords
- nucleic acid
- acid molecule
- composition containing
- containing nucleic
- molecule stably
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C12N2310/3519—Fusion with another nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
- C12N2310/531—Stem-loop; Hairpin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/50—Methods for regulating/modulating their activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014267087 | 2014-12-29 | ||
| JP2015081298 | 2015-04-10 | ||
| PCT/JP2015/080849 WO2016108264A1 (ja) | 2014-12-29 | 2015-10-30 | 核酸分子を安定に含有する組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201705312PA true SG11201705312PA (en) | 2017-07-28 |
Family
ID=56284418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201705312PA SG11201705312PA (en) | 2014-12-29 | 2015-10-30 | Composition containing nucleic acid molecule stably |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20180036409A1 (he) |
| EP (1) | EP3241903A4 (he) |
| JP (2) | JP6462723B2 (he) |
| KR (2) | KR102585112B1 (he) |
| CN (1) | CN107208094A (he) |
| AU (2) | AU2015373071B2 (he) |
| BR (1) | BR112017014090A2 (he) |
| CA (1) | CA2971830A1 (he) |
| HK (1) | HK1244030A1 (he) |
| IL (1) | IL252905B (he) |
| MX (1) | MX2017008730A (he) |
| RU (1) | RU2723032C2 (he) |
| SG (1) | SG11201705312PA (he) |
| WO (1) | WO2016108264A1 (he) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2018005146A (es) | 2015-10-30 | 2018-08-23 | Bonac Corp | Composicion que contiene de manera estable molecula de acido nucleico de un solo filamento que suprime la expresion de gen tgf-b1. |
| FR3058061A1 (fr) * | 2016-10-27 | 2018-05-04 | Selexel | Nouvelle utilisation d'oligonucleotides double brin |
| EP3532086A1 (fr) * | 2016-10-27 | 2019-09-04 | Selexel | Nouvel oligonucleotide double brin bisquecifiques pour le traitement des cancers |
| CN106857502A (zh) * | 2017-03-03 | 2017-06-20 | 湖北新纵科病毒疾病工程技术有限公司 | 一种防止rna降解的样品保存液以及保存方法 |
| SG11201913541QA (en) | 2017-07-28 | 2020-02-27 | Kyorin Pharmaceutical Co Ltd | Therapeutic agent for fibrosis |
| WO2019074110A1 (ja) | 2017-10-13 | 2019-04-18 | 株式会社ボナック | 一本鎖核酸分子およびその製造方法 |
| MX2020009532A (es) * | 2018-03-13 | 2020-10-05 | Janssen Pharmaceutica Nv | Oligonucleotidos modificados para uso en el tratamiento de tauopatias. |
| CN109402127B (zh) * | 2018-09-29 | 2021-12-10 | 复旦大学附属眼耳鼻喉科医院 | 一组与结缔组织生长因子特异性结合的高亲和力核酸适配体及其应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58102724A (ja) | 1981-12-15 | 1983-06-18 | Mitsubishi Chem Ind Ltd | 防滑性ポリプロピレン成形品 |
| BR9106751A (pt) | 1990-08-16 | 1993-08-17 | Isis Pharmaceuticals Ind | Oligonucleotideo ou analogo de nucleotideo e processo para modulacao da atividade de uma infeccao por citomegalovirus |
| DE69732029T2 (de) * | 1996-04-26 | 2006-02-23 | Merck & Co., Inc. | Dna enthaltende impfstoffen |
| CA2269072C (en) | 1996-10-25 | 2006-02-14 | Nexstar Pharmaceuticals, Inc. | Vascular endothelial growth factor (vegf) nucleic acid ligand complexes |
| ZA99493B (en) * | 1998-01-30 | 1999-07-22 | Akzo Nobel Nv | Method for the isolation of nucleic acid. |
| WO1999045966A1 (en) * | 1998-03-13 | 1999-09-16 | American Home Products Corporation | Polynucleotide composition, method of preparation, and use thereof |
| DE19836559A1 (de) * | 1998-08-12 | 2000-03-23 | Antigen Gmbh | Gefäß zur Entnahme von Blut |
| JP3967516B2 (ja) * | 2000-02-29 | 2007-08-29 | ハイモ株式会社 | Ｄｎａの電気泳動法 |
| WO2001040789A1 (fr) * | 1999-12-02 | 2001-06-07 | Hymo Corporation | Gels de polyacrylamide premoules pour l'electrophorese, procede de production de ces derniers et procede d'electrophorese dans lequel on utilise ces gels |
| DE10006662A1 (de) * | 2000-02-15 | 2001-08-23 | Antigen Produktions Gmbh | Gefäß zur Nukleinsäureanalytik |
| US20040058886A1 (en) * | 2002-08-08 | 2004-03-25 | Dharmacon, Inc. | Short interfering RNAs having a hairpin structure containing a non-nucleotide loop |
| US7511131B2 (en) | 2002-11-13 | 2009-03-31 | Genzyme Corporation | Antisense modulation of apolipoprotein B expression |
| AU2004246905B2 (en) * | 2003-06-18 | 2010-01-21 | Biolab Ltd. | Sphingoid polyalkylamine conjugates for vaccination |
| AU2004272748C1 (en) * | 2003-09-17 | 2010-07-08 | Centelion | Method of preparation of pharmaceutically grade plasmid DNA |
| KR20070058621A (ko) * | 2004-09-17 | 2007-06-08 | 센텔리옹 에스아에스 | 플라스미드 ｄｎａ의 안정한 액체 제제 |
| DE102005023170A1 (de) * | 2005-05-19 | 2006-11-23 | Curevac Gmbh | Optimierte Formulierung für mRNA |
| TW200808360A (en) * | 2006-04-13 | 2008-02-16 | Alcon Mfg Ltd | RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions |
| WO2009086558A1 (en) * | 2008-01-02 | 2009-07-09 | Tekmira Pharmaceuticals Corporation | Improved compositions and methods for the delivery of nucleic acids |
| JP5608998B2 (ja) * | 2009-03-31 | 2014-10-22 | 東洋紡株式会社 | 保存安定性に優れた核酸増幅検出試薬キット |
| US8691782B2 (en) * | 2010-08-03 | 2014-04-08 | Bonac Corporation | Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton |
| EP3202760B1 (en) * | 2011-01-11 | 2019-08-21 | Alnylam Pharmaceuticals, Inc. | Pegylated lipids and their use for drug delivery |
| CN103906503B (zh) * | 2011-11-04 | 2016-12-14 | 日东电工株式会社 | 用于无菌制备脂质-核酸颗粒的单次使用系统 |
| ME03429B (me) * | 2012-03-15 | 2020-01-20 | Acraf | Kationski polimeri na bazi glikogena |
| EP2846839B1 (en) * | 2012-05-10 | 2019-02-20 | Adynxx, Inc. | Formulations for the delivery of active ingredients |
| AU2013380825B2 (en) * | 2012-10-16 | 2017-07-20 | Biomics Biotechnologies Co., Ltd. | Lipidosome preparation, preparation method and application thereof |
-
2015
- 2015-10-30 WO PCT/JP2015/080849 patent/WO2016108264A1/ja active Application Filing
- 2015-10-30 MX MX2017008730A patent/MX2017008730A/es unknown
- 2015-10-30 SG SG11201705312PA patent/SG11201705312PA/en unknown
- 2015-10-30 KR KR1020177020431A patent/KR102585112B1/ko active IP Right Grant
- 2015-10-30 US US15/538,550 patent/US20180036409A1/en not_active Abandoned
- 2015-10-30 CN CN201580071781.6A patent/CN107208094A/zh active Pending
- 2015-10-30 AU AU2015373071A patent/AU2015373071B2/en active Active
- 2015-10-30 KR KR1020227003919A patent/KR20220035404A/ko not_active IP Right Cessation
- 2015-10-30 BR BR112017014090-0A patent/BR112017014090A2/pt not_active Application Discontinuation
- 2015-10-30 CA CA2971830A patent/CA2971830A1/en active Pending
- 2015-10-30 JP JP2016567299A patent/JP6462723B2/ja active Active
- 2015-10-30 RU RU2017126568A patent/RU2723032C2/ru active
- 2015-10-30 EP EP15875390.5A patent/EP3241903A4/en active Pending
-
2017
- 2017-06-14 IL IL252905A patent/IL252905B/he active IP Right Grant
-
2018
- 2018-03-14 HK HK18103545.4A patent/HK1244030A1/zh unknown
- 2018-12-27 JP JP2018244851A patent/JP6808710B2/ja not_active Expired - Fee Related
-
2022
- 2022-06-22 AU AU2022204391A patent/AU2022204391A1/en active Pending
-
2023
- 2023-08-30 US US18/458,317 patent/US20240016937A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015373071B2 (en) | 2022-03-31 |
| KR20220035404A (ko) | 2022-03-22 |
| AU2015373071A1 (en) | 2017-07-13 |
| KR20170094797A (ko) | 2017-08-21 |
| JP2019077696A (ja) | 2019-05-23 |
| BR112017014090A2 (pt) | 2018-03-06 |
| JP6808710B2 (ja) | 2021-01-06 |
| CA2971830A1 (en) | 2016-07-07 |
| RU2723032C2 (ru) | 2020-06-08 |
| JP6462723B2 (ja) | 2019-01-30 |
| US20240016937A1 (en) | 2024-01-18 |
| IL252905B (he) | 2020-09-30 |
| EP3241903A4 (en) | 2018-07-04 |
| RU2017126568A3 (he) | 2019-05-20 |
| MX2017008730A (es) | 2017-11-17 |
| HK1244030A1 (zh) | 2018-07-27 |
| KR102585112B1 (ko) | 2023-10-10 |
| CN107208094A (zh) | 2017-09-26 |
| AU2022204391A1 (en) | 2022-07-14 |
| RU2017126568A (ru) | 2019-01-31 |
| JPWO2016108264A1 (ja) | 2017-08-31 |
| IL252905A0 (he) | 2017-08-31 |
| WO2016108264A1 (ja) | 2016-07-07 |
| EP3241903A1 (en) | 2017-11-08 |
| US20180036409A1 (en) | 2018-02-08 |
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