SG11201703748PA - Nucleic acid compounds for binding growth differentiation factor 11 - Google Patents

Nucleic acid compounds for binding growth differentiation factor 11

Info

Publication number
SG11201703748PA
SG11201703748PA SG11201703748PA SG11201703748PA SG11201703748PA SG 11201703748P A SG11201703748P A SG 11201703748PA SG 11201703748P A SG11201703748P A SG 11201703748PA SG 11201703748P A SG11201703748P A SG 11201703748PA SG 11201703748P A SG11201703748P A SG 11201703748PA
Authority
SG
Singapore
Prior art keywords
nucleic acid
acid compounds
differentiation factor
growth differentiation
binding growth
Prior art date
Application number
SG11201703748PA
Other languages
English (en)
Inventor
Urs Ochsner
Louis Green
Dom Zichi
Nebojsa Janjic
Original Assignee
Somalogic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somalogic Inc filed Critical Somalogic Inc
Publication of SG11201703748PA publication Critical patent/SG11201703748PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/16Aptamers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/495Transforming growth factor [TGF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201703748PA 2014-11-24 2015-11-23 Nucleic acid compounds for binding growth differentiation factor 11 SG11201703748PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462083592P 2014-11-24 2014-11-24
US201562113864P 2015-02-09 2015-02-09
PCT/US2015/062155 WO2016085860A1 (en) 2014-11-24 2015-11-23 Nucleic acid compounds for binding growth differentiation factor 11

Publications (1)

Publication Number Publication Date
SG11201703748PA true SG11201703748PA (en) 2017-06-29

Family

ID=55069068

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201703748PA SG11201703748PA (en) 2014-11-24 2015-11-23 Nucleic acid compounds for binding growth differentiation factor 11

Country Status (14)

Country Link
US (3) US10808251B2 (ru)
EP (1) EP3224361B1 (ru)
JP (2) JP6768651B2 (ru)
KR (1) KR102558890B1 (ru)
CN (1) CN107075518B (ru)
AU (1) AU2015353767B2 (ru)
BR (1) BR112017008476B1 (ru)
CA (1) CA2966925C (ru)
IL (1) IL251934B (ru)
MX (1) MX2017006521A (ru)
RU (1) RU2708170C2 (ru)
SG (1) SG11201703748PA (ru)
TW (1) TWI695068B (ru)
WO (1) WO2016085860A1 (ru)

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660985A (en) 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
KR970002255B1 (ko) 1990-06-11 1997-02-26 넥스스타 파아마슈티컬드, 인크. 핵산 리간드
US6001577A (en) 1998-06-08 1999-12-14 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
US5763177A (en) 1990-06-11 1998-06-09 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
US5705337A (en) 1990-06-11 1998-01-06 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chemi-SELEX
US5580737A (en) 1990-06-11 1996-12-03 Nexstar Pharmaceuticals, Inc. High-affinity nucleic acid ligands that discriminate between theophylline and caffeine
US5719273A (en) 1993-06-14 1998-02-17 Nexstar Pharmaceuticals, Inc. Palladium catalyzed nucleoside modifications methods using nucleophiles and carbon monoxide
US6458539B1 (en) 1993-09-17 2002-10-01 Somalogic, Inc. Photoselection of nucleic acid ligands
US5945527A (en) 1996-05-30 1999-08-31 Nexstar Pharmaceuticals, Inc. Palladium catalyzed nucleoside modification methods using nucleophiles and carbon monoxide
AU8666398A (en) * 1997-08-01 1999-02-22 Johns Hopkins University School Of Medicine, The Methods to identify growth differentiation factor (gdf) receptors
US6242246B1 (en) 1997-12-15 2001-06-05 Somalogic, Inc. Nucleic acid ligand diagnostic Biochip
US6376190B1 (en) 2000-09-22 2002-04-23 Somalogic, Inc. Modified SELEX processes without purified protein
EA015916B1 (ru) * 2006-09-05 2011-12-30 Эли Лилли Энд Компани Моноклональные антитела к миостатину и их применения
US7855054B2 (en) 2007-01-16 2010-12-21 Somalogic, Inc. Multiplexed analyses of test samples
US7947447B2 (en) 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
EP2172566B2 (en) 2007-07-17 2022-05-18 Somalogic, Inc. Method for generating aptamers with improved off-rates
PE20091163A1 (es) * 2007-11-01 2009-08-09 Wyeth Corp Anticuerpos para gdf8
JO3340B1 (ar) * 2010-05-26 2019-03-13 Regeneron Pharma مضادات حيوية لـعامل تمايز النمو 8 البشري
JP2013537425A (ja) 2010-08-16 2013-10-03 アムジエン・インコーポレーテツド ミオスタチンに結合するポリペプチド、組成物および方法
JP6124986B2 (ja) 2012-03-19 2017-05-10 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. 拡張期心不全を処置するための増殖分化因子(gdf)
AU2013334659B2 (en) * 2012-10-24 2019-07-11 Celgene Corporation Biomarker for use in treating anemia
US10092627B2 (en) * 2013-04-08 2018-10-09 President And Fellows Of Harvard College Methods and compositions for rejuvenating skeletal muscle stem cells
SG11201602063UA (en) 2013-09-24 2016-04-28 Somalogic Inc Multiaptamer target detection

Also Published As

Publication number Publication date
IL251934B (en) 2021-07-29
BR112017008476A2 (pt) 2018-01-09
JP6858911B2 (ja) 2021-04-14
KR102558890B1 (ko) 2023-07-21
US20230193287A1 (en) 2023-06-22
CA2966925C (en) 2023-08-29
AU2015353767B2 (en) 2021-09-09
US20210130829A1 (en) 2021-05-06
EP3224361B1 (en) 2019-06-19
CN107075518A (zh) 2017-08-18
TW201638335A (zh) 2016-11-01
IL251934A0 (en) 2017-06-29
BR112017008476A8 (pt) 2022-10-18
JP2021000118A (ja) 2021-01-07
US20190024087A1 (en) 2019-01-24
KR20170084068A (ko) 2017-07-19
RU2708170C2 (ru) 2019-12-04
RU2017121801A3 (ru) 2019-05-27
JP2017536118A (ja) 2017-12-07
JP6768651B2 (ja) 2020-10-14
CA2966925A1 (en) 2016-06-02
NZ731836A (en) 2023-11-24
MX2017006521A (es) 2017-08-09
CN107075518B (zh) 2021-03-09
WO2016085860A1 (en) 2016-06-02
US10808251B2 (en) 2020-10-20
US11535852B2 (en) 2022-12-27
AU2015353767A1 (en) 2017-05-25
EP3224361A1 (en) 2017-10-04
BR112017008476B1 (pt) 2024-03-12
RU2017121801A (ru) 2018-12-26
TWI695068B (zh) 2020-06-01

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