SG11201602063UA - Multiaptamer target detection - Google Patents
Multiaptamer target detectionInfo
- Publication number
- SG11201602063UA SG11201602063UA SG11201602063UA SG11201602063UA SG11201602063UA SG 11201602063U A SG11201602063U A SG 11201602063UA SG 11201602063U A SG11201602063U A SG 11201602063UA SG 11201602063U A SG11201602063U A SG 11201602063UA SG 11201602063U A SG11201602063U A SG 11201602063UA
- Authority
- SG
- Singapore
- Prior art keywords
- multiaptamer
- target detection
- target
- detection
- multiaptamer target
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1048—SELEX
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/33—Chemical structure of the base
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/10—Applications; Uses in screening processes
- C12N2320/13—Applications; Uses in screening processes in a process of directed evolution, e.g. SELEX, acquiring a new function
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/205—Aptamer
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361881629P | 2013-09-24 | 2013-09-24 | |
| PCT/US2014/057143 WO2015048084A1 (en) | 2013-09-24 | 2014-09-24 | Multiaptamer target detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201602063UA true SG11201602063UA (en) | 2016-04-28 |
Family
ID=52744404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201602063UA SG11201602063UA (en) | 2013-09-24 | 2014-09-24 | Multiaptamer target detection |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9926566B2 (en) |
| EP (1) | EP3049523B1 (en) |
| JP (1) | JP6506768B2 (en) |
| KR (1) | KR102348283B1 (en) |
| CN (2) | CN114703193A (en) |
| AU (1) | AU2014326975B2 (en) |
| BR (1) | BR112016005957A2 (en) |
| CA (1) | CA2924987C (en) |
| HK (1) | HK1218765A1 (en) |
| IL (1) | IL244284B (en) |
| MX (1) | MX361451B (en) |
| SG (1) | SG11201602063UA (en) |
| WO (1) | WO2015048084A1 (en) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201602063UA (en) | 2013-09-24 | 2016-04-28 | Somalogic Inc | Multiaptamer target detection |
| JP6768651B2 (en) | 2014-11-24 | 2020-10-14 | ソマロジック, インコーポレイテッドSomaLogic, Inc. | Nucleic acid compound for binding to proliferative differentiation factor 11 |
| US11332784B2 (en) * | 2015-12-08 | 2022-05-17 | Twinstrand Biosciences, Inc. | Adapters, methods, and compositions for duplex sequencing |
| SG10201911357VA (en) | 2016-03-14 | 2020-01-30 | Somalogic Inc | Compounds and methods for the synthesis of 5-(n-protected-tryptaminocarboxyamide)-2'-deoxyuridine phosphoramidate for incorporation into a nucleic sequence |
| EP3472357A4 (en) * | 2016-06-17 | 2020-01-22 | Proximity Biosciences, LLC | Method for aptamer pair selection |
| RU2021137915A (en) * | 2016-07-01 | 2022-02-04 | Сомалоджик, Инк. | OLIGONUCLEOTIDES CONTAINING MODIFIED NUCLEOSIDES |
| JP2020514746A (en) | 2016-12-01 | 2020-05-21 | ノーティラス バイオテクノロジー インコーポレイテッド | How to assay proteins |
| WO2019103131A1 (en) * | 2017-11-24 | 2019-05-31 | 国立大学法人 東京大学 | Method for distinguishing binding sites of aptamers, method for measuring dissociation constant of ternary complex, or the like, comprising aptamer pair and target substance, and method for selecting optimum aptamer pair |
| MX2020013814A (en) * | 2018-06-22 | 2021-04-13 | Somalogic Operating Co Inc | Improved proteomic multiplex assays. |
| EP4165549A1 (en) | 2020-06-11 | 2023-04-19 | Nautilus Biotechnology, Inc. | Methods and systems for computational decoding of biological, chemical, and physical entities |
| CA3203106A1 (en) | 2021-01-20 | 2022-07-28 | Parag Mallick | Systems and methods for biomolecule quantitation |
| AU2022209365A1 (en) | 2021-01-21 | 2023-07-20 | Nautilus Subsidiary, Inc. | Systems and methods for biomolecule preparation |
| IL305336A (en) | 2021-03-11 | 2023-10-01 | Nautilus Subsidiary Inc | Systems and methods for biomolecule retention |
| US20230070896A1 (en) | 2021-09-09 | 2023-03-09 | Nautilus Biotechnology, Inc. | Characterization and localization of protein modifications |
| WO2023049073A1 (en) | 2021-09-22 | 2023-03-30 | Nautilus Biotechnology, Inc. | Methods and systems for determining polypeptide interactions |
| WO2023081728A1 (en) | 2021-11-03 | 2023-05-11 | Nautilus Biotechnology, Inc. | Systems and methods for surface structuring |
| WO2023192917A1 (en) | 2022-03-29 | 2023-10-05 | Nautilus Subsidiary, Inc. | Integrated arrays for single-analyte processes |
| US20230360732A1 (en) | 2022-04-25 | 2023-11-09 | Nautilus Subsidiary, Inc. | Systems and methods for assessing and improving the quality of multiplex molecular assays |
| WO2023250364A1 (en) | 2022-06-21 | 2023-12-28 | Nautilus Subsidiary, Inc. | Method for detecting analytes at sites of optically non-resolvable distances |
| WO2024059655A1 (en) | 2022-09-15 | 2024-03-21 | Nautilus Subsidiary, Inc. | Characterizing accessibility of macromolecule structures |
| WO2024073599A1 (en) | 2022-09-29 | 2024-04-04 | Nautilus Subsidiary, Inc. | Preparation of array surfaces for single-analyte processes |
| WO2024107857A1 (en) | 2022-11-15 | 2024-05-23 | Nautilus Subsidiary, Inc. | Standard polypeptides |
| WO2024124073A1 (en) | 2022-12-09 | 2024-06-13 | Nautilus Subsidiary, Inc. | A method comprising performing on a single-analyte array at least 50 cycles of a process |
| WO2024130000A1 (en) | 2022-12-15 | 2024-06-20 | Nautilus Subsidiary, Inc. | Inhibition of photon phenomena on single molecule arrays |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001257091A1 (en) * | 2000-04-18 | 2001-10-30 | Gilead Sciences, Inc. | Aptamer based two-site binding assay |
| EP1330544A4 (en) * | 2000-09-26 | 2005-04-06 | Univ Duke | Rna aptamers and methods for identifying the same |
| US20070071744A1 (en) | 2002-06-07 | 2007-03-29 | Gotz Munch | Agents which bind to epitopes of glycoprotein VI |
| US7595160B2 (en) | 2004-01-13 | 2009-09-29 | U.S. Genomics, Inc. | Analyte detection using barcoded polymers |
| US7795009B2 (en) * | 2005-06-15 | 2010-09-14 | Saint Louis University | Three-component biosensors for detecting macromolecules and other analytes |
| WO2007056250A2 (en) | 2005-11-04 | 2007-05-18 | U.S. Genomics, Inc. | Heterogeneous assay of analytes in solution using polymers |
| WO2008039642A2 (en) | 2006-09-26 | 2008-04-03 | Replidyne, Inc. | Methods and compounds for treatment of clostridium based infection |
| US7947447B2 (en) | 2007-01-16 | 2011-05-24 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| EP2172566B2 (en) * | 2007-07-17 | 2022-05-18 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| US20100239682A1 (en) | 2007-09-17 | 2010-09-23 | Antoine Andremont | Colonic delivery of antimicrobial agents |
| US8569252B2 (en) | 2009-04-15 | 2013-10-29 | Postech Academy-Industry Foundation | Nucleolin specific aptamer and use thereof |
| EP2534164A4 (en) | 2010-02-11 | 2013-09-11 | Intelligent Med Devices Inc | Oligonucleotides relating to clostridium difficile genes encoding toxin b, toxin a, or binary toxin |
| GB201002627D0 (en) | 2010-02-16 | 2010-03-31 | Loxbridge Res Llp | Aptamer based analyte detection method |
| EP3345915B1 (en) * | 2010-04-12 | 2021-11-24 | Somalogic, Inc. | 5-position modified pyrimidines and their use |
| US8785132B2 (en) | 2010-04-23 | 2014-07-22 | Postech Academy-Industry Foundation | Aptamer sandwich assays |
| AU2012225273B2 (en) | 2011-03-10 | 2016-10-13 | Somalogic, Inc. | Aptamers for Clostridium difficile diagnostics |
| US20150031585A1 (en) | 2011-03-10 | 2015-01-29 | Somalogic, Inc. | Multiaptamer Target Detection |
| RU2564855C2 (en) * | 2011-04-26 | 2015-10-10 | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" | Method of obtaining pegylated oligonucleotides |
| RU2651708C2 (en) * | 2011-09-30 | 2018-04-23 | Сомалоджик, Инк. | Cardiovascular risk event prediction and uses thereof |
| MX2018004950A (en) | 2011-12-30 | 2022-01-24 | Quest Diagnostics Invest Inc | Aptamers and diagnostic methods for detecting the egf receptor. |
| SG11201602063UA (en) | 2013-09-24 | 2016-04-28 | Somalogic Inc | Multiaptamer target detection |
-
2014
- 2014-09-24 SG SG11201602063UA patent/SG11201602063UA/en unknown
- 2014-09-24 CA CA2924987A patent/CA2924987C/en active Active
- 2014-09-24 CN CN202210264586.7A patent/CN114703193A/en active Pending
- 2014-09-24 BR BR112016005957A patent/BR112016005957A2/en not_active IP Right Cessation
- 2014-09-24 MX MX2016003320A patent/MX361451B/en active IP Right Grant
- 2014-09-24 JP JP2016544355A patent/JP6506768B2/en active Active
- 2014-09-24 CN CN201480051210.1A patent/CN105555957A/en active Pending
- 2014-09-24 EP EP14847780.5A patent/EP3049523B1/en active Active
- 2014-09-24 AU AU2014326975A patent/AU2014326975B2/en active Active
- 2014-09-24 US US15/023,182 patent/US9926566B2/en active Active
- 2014-09-24 WO PCT/US2014/057143 patent/WO2015048084A1/en active Application Filing
- 2014-09-24 KR KR1020167006262A patent/KR102348283B1/en active IP Right Grant
-
2016
- 2016-02-25 IL IL244284A patent/IL244284B/en active IP Right Grant
- 2016-06-13 HK HK16106780.3A patent/HK1218765A1/en unknown
-
2018
- 2018-02-13 US US15/895,723 patent/US10392621B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BR112016005957A2 (en) | 2017-09-26 |
| CA2924987A1 (en) | 2015-04-02 |
| HK1218765A1 (en) | 2017-03-10 |
| KR20160058777A (en) | 2016-05-25 |
| US10392621B2 (en) | 2019-08-27 |
| IL244284B (en) | 2019-12-31 |
| EP3049523A1 (en) | 2016-08-03 |
| KR102348283B1 (en) | 2022-01-10 |
| MX361451B (en) | 2018-12-06 |
| EP3049523A4 (en) | 2017-05-17 |
| CN105555957A (en) | 2016-05-04 |
| MX2016003320A (en) | 2016-05-31 |
| AU2014326975A2 (en) | 2017-01-05 |
| US20180187197A1 (en) | 2018-07-05 |
| JP2016531593A (en) | 2016-10-13 |
| AU2014326975B2 (en) | 2020-05-07 |
| JP6506768B2 (en) | 2019-04-24 |
| EP3049523B1 (en) | 2019-08-07 |
| CN114703193A (en) | 2022-07-05 |
| CA2924987C (en) | 2022-08-16 |
| US9926566B2 (en) | 2018-03-27 |
| AU2014326975A1 (en) | 2016-04-07 |
| IL244284A0 (en) | 2016-04-21 |
| US20160237435A1 (en) | 2016-08-18 |
| WO2015048084A1 (en) | 2015-04-02 |
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