SG11201701573QA - Heteroaryl compounds as btk inhibitors and uses thereof - Google Patents
Heteroaryl compounds as btk inhibitors and uses thereofInfo
- Publication number
- SG11201701573QA SG11201701573QA SG11201701573QA SG11201701573QA SG11201701573QA SG 11201701573Q A SG11201701573Q A SG 11201701573QA SG 11201701573Q A SG11201701573Q A SG 11201701573QA SG 11201701573Q A SG11201701573Q A SG 11201701573QA SG 11201701573Q A SG11201701573Q A SG 11201701573QA
- Authority
- SG
- Singapore
- Prior art keywords
- heteroaryl compounds
- btk inhibitors
- btk
- heteroaryl
- inhibitors
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462060249P | 2014-10-06 | 2014-10-06 | |
PCT/US2015/054221 WO2016057500A1 (en) | 2014-10-06 | 2015-10-06 | Heteroaryl compounds as btk inhibitors and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201701573QA true SG11201701573QA (en) | 2017-03-30 |
Family
ID=54337891
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201701573QA SG11201701573QA (en) | 2014-10-06 | 2015-10-06 | Heteroaryl compounds as btk inhibitors and uses thereof |
Country Status (19)
Country | Link |
---|---|
US (2) | US10253023B2 (pt) |
EP (1) | EP3204382B1 (pt) |
JP (1) | JP6856526B2 (pt) |
KR (1) | KR102523111B1 (pt) |
CN (1) | CN107001362A (pt) |
AR (1) | AR102177A1 (pt) |
AU (1) | AU2015328285B2 (pt) |
BR (1) | BR112017006305B1 (pt) |
CA (1) | CA2960401C (pt) |
CL (1) | CL2017000786A1 (pt) |
ES (1) | ES2907622T3 (pt) |
IL (1) | IL251441B (pt) |
MX (1) | MX2017004200A (pt) |
NZ (1) | NZ729603A (pt) |
PH (1) | PH12017500408A1 (pt) |
RU (1) | RU2742122C2 (pt) |
SG (1) | SG11201701573QA (pt) |
WO (1) | WO2016057500A1 (pt) |
ZA (1) | ZA201701501B (pt) |
Families Citing this family (58)
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RS57662B1 (sr) * | 2013-12-11 | 2018-11-30 | Biogen Ma Inc | Biaril jedinjenja korisna za lečenje humanih bolesti u onkologiji, neurologiji i imunologiji |
EP3365340B1 (en) | 2015-10-19 | 2022-08-10 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
MD3377488T2 (ro) | 2015-11-19 | 2023-02-28 | Incyte Corp | Compuși heterociclici ca imunomodulatori |
SG11201805300QA (en) | 2015-12-22 | 2018-07-30 | Incyte Corp | Heterocyclic compounds as immunomodulators |
ES2906460T3 (es) | 2016-05-06 | 2022-04-18 | Incyte Corp | Compuestos heterocíclicos como inmunomoduladores |
TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Hdac抑制劑與pd-l1抑制劑之組合治療 |
TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
US20170342060A1 (en) | 2016-05-26 | 2017-11-30 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
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JP6954994B2 (ja) * | 2016-08-16 | 2021-10-27 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | 可逆性btk阻害剤としてのオキソ−イミダゾピリジン及びその使用 |
ES2941716T3 (es) | 2016-08-29 | 2023-05-25 | Incyte Corp | Compuestos heterocíclicos como inmunomoduladores |
KR102507967B1 (ko) | 2016-09-09 | 2023-03-09 | 인사이트 코포레이션 | Hpk1 조절제로서의 피라졸로피리딘 유도체 및 암을 치료하기 위한 이의 용도 |
WO2018049191A1 (en) | 2016-09-09 | 2018-03-15 | Incyte Corporation | Pyrazolopyridone derivatives as hpk1 modulators and uses thereof for the treatment of cancer |
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WO2018049214A1 (en) | 2016-09-09 | 2018-03-15 | Incyte Corporation | Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer |
HRP20221216T1 (hr) | 2016-12-22 | 2022-12-23 | Incyte Corporation | Derivati tetrahidro imidazo[4,5-c]piridina kao induktori internalizacije pd-l1 |
US20180179201A1 (en) | 2016-12-22 | 2018-06-28 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
US20180179179A1 (en) | 2016-12-22 | 2018-06-28 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
ES2934230T3 (es) | 2016-12-22 | 2023-02-20 | Incyte Corp | Derivados de benzooxazol como inmunomoduladores |
WO2018152220A1 (en) | 2017-02-15 | 2018-08-23 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
CN106939009A (zh) * | 2017-03-31 | 2017-07-11 | 牡丹江医学院 | 一种用于治疗脑震荡的药物及其制备方法 |
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US10722495B2 (en) | 2017-09-08 | 2020-07-28 | Incyte Corporation | Cyanoindazole compounds and uses thereof |
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CN107001362A (zh) | 2017-08-01 |
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US20190233417A1 (en) | 2019-08-01 |
PH12017500408A1 (en) | 2017-07-17 |
MX2017004200A (es) | 2017-06-15 |
BR112017006305A2 (pt) | 2017-12-12 |
EP3204382B1 (en) | 2021-12-01 |
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CL2017000786A1 (es) | 2017-12-29 |
AU2015328285B2 (en) | 2019-07-18 |
US11098041B2 (en) | 2021-08-24 |
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RU2742122C2 (ru) | 2021-02-02 |
KR102523111B1 (ko) | 2023-04-18 |
RU2017115852A3 (pt) | 2019-04-19 |
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