SG11201610857TA - Cultured mammalian limbal stem cells, methods for generating the same, and uses thereof - Google Patents

Cultured mammalian limbal stem cells, methods for generating the same, and uses thereof

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Publication number
SG11201610857TA
SG11201610857TA SG11201610857TA SG11201610857TA SG11201610857TA SG 11201610857T A SG11201610857T A SG 11201610857TA SG 11201610857T A SG11201610857T A SG 11201610857TA SG 11201610857T A SG11201610857T A SG 11201610857TA SG 11201610857T A SG11201610857T A SG 11201610857TA
Authority
SG
Singapore
Prior art keywords
generating
methods
same
stem cells
cultured mammalian
Prior art date
Application number
SG11201610857TA
Other languages
English (en)
Inventor
Kang Zhang
Hong Quyang
Rui Hou
Huimin Cai
Original Assignee
Univ California
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Publication date
Application filed by Univ California filed Critical Univ California
Publication of SG11201610857TA publication Critical patent/SG11201610857TA/en

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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12N2501/727—Kinases (EC 2.7.)
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

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  • Health & Medical Sciences (AREA)
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  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
SG11201610857TA 2014-06-27 2015-06-29 Cultured mammalian limbal stem cells, methods for generating the same, and uses thereof SG11201610857TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462018396P 2014-06-27 2014-06-27
PCT/US2015/038384 WO2015200920A1 (fr) 2014-06-27 2015-06-29 Cellules souches limbiques de mammifères en culture, leurs méthodes de production et leurs utilisations

Publications (1)

Publication Number Publication Date
SG11201610857TA true SG11201610857TA (en) 2017-01-27

Family

ID=54938873

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201610857TA SG11201610857TA (en) 2014-06-27 2015-06-29 Cultured mammalian limbal stem cells, methods for generating the same, and uses thereof
SG10201806498RA SG10201806498RA (en) 2014-06-27 2015-06-29 Cultured mammalian limbal stem cells, methods for generating the same, and uses thereof

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SG10201806498RA SG10201806498RA (en) 2014-06-27 2015-06-29 Cultured mammalian limbal stem cells, methods for generating the same, and uses thereof

Country Status (10)

Country Link
US (1) US20170233698A1 (fr)
EP (1) EP3161127A4 (fr)
JP (1) JP2017522016A (fr)
KR (1) KR20170020527A (fr)
CN (1) CN107075469A (fr)
CA (1) CA2953524A1 (fr)
IL (1) IL249828A0 (fr)
MX (1) MX2017000181A (fr)
SG (2) SG11201610857TA (fr)
WO (1) WO2015200920A1 (fr)

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CN115068504A (zh) * 2021-03-12 2022-09-20 广州康睿生物医药科技股份有限公司 一种角膜修复材料及其制备方法和用途
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CN115094038A (zh) * 2022-07-15 2022-09-23 中国医学科学院北京协和医院 一种角膜基质细胞原代培养的方法
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EP3161127A1 (fr) 2017-05-03
IL249828A0 (en) 2017-02-28
WO2015200920A1 (fr) 2015-12-30
CN107075469A (zh) 2017-08-18
EP3161127A4 (fr) 2018-06-06
CA2953524A1 (fr) 2015-12-30
MX2017000181A (es) 2017-05-01
JP2017522016A (ja) 2017-08-10
KR20170020527A (ko) 2017-02-22
SG10201806498RA (en) 2018-08-30
WO2015200920A8 (fr) 2017-04-06

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