SG11201602068QA - Fusion protein - Google Patents

Fusion protein

Info

Publication number
SG11201602068QA
SG11201602068QA SG11201602068QA SG11201602068QA SG11201602068QA SG 11201602068Q A SG11201602068Q A SG 11201602068QA SG 11201602068Q A SG11201602068Q A SG 11201602068QA SG 11201602068Q A SG11201602068Q A SG 11201602068QA SG 11201602068Q A SG11201602068Q A SG 11201602068QA
Authority
SG
Singapore
Prior art keywords
fusion protein
fusion
protein
Prior art date
Application number
SG11201602068QA
Other languages
English (en)
Inventor
Simon Westbrook
Original Assignee
Levicept Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Levicept Ltd filed Critical Levicept Ltd
Publication of SG11201602068QA publication Critical patent/SG11201602068QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2807Headache; Migraine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2842Pain, e.g. neuropathic pain, psychogenic pain

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
SG11201602068QA 2013-09-18 2014-09-18 Fusion protein SG11201602068QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1316592.3A GB201316592D0 (en) 2013-09-18 2013-09-18 Fusion protein
PCT/GB2014/052833 WO2015040398A1 (fr) 2013-09-18 2014-09-18 Protéine de fusion

Publications (1)

Publication Number Publication Date
SG11201602068QA true SG11201602068QA (en) 2016-04-28

Family

ID=49552839

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201602068QA SG11201602068QA (en) 2013-09-18 2014-09-18 Fusion protein

Country Status (25)

Country Link
US (3) US9873728B2 (fr)
EP (1) EP3046934B1 (fr)
JP (3) JP6681834B2 (fr)
KR (1) KR102205633B1 (fr)
CN (1) CN105873943B (fr)
AU (1) AU2014322842B2 (fr)
CA (1) CA2924410C (fr)
CY (1) CY1121347T1 (fr)
DK (1) DK3046934T3 (fr)
EA (1) EA037416B1 (fr)
ES (1) ES2714694T3 (fr)
GB (1) GB201316592D0 (fr)
HR (1) HRP20190434T1 (fr)
HU (1) HUE043273T2 (fr)
IL (1) IL244588B (fr)
LT (1) LT3046934T (fr)
MX (1) MX2016003530A (fr)
NZ (1) NZ718044A (fr)
PL (1) PL3046934T3 (fr)
PT (1) PT3046934T (fr)
RS (1) RS58463B1 (fr)
SG (1) SG11201602068QA (fr)
SI (1) SI3046934T1 (fr)
TR (1) TR201903490T4 (fr)
WO (1) WO2015040398A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ628685A (en) 2012-03-14 2017-12-22 Levicept Ltd Therapeutic use of p75ntr neurotrophin binding protein
GB201316592D0 (en) * 2013-09-18 2013-10-30 Levicept Ltd Fusion protein
GB201412748D0 (en) * 2014-07-17 2014-09-03 Levicept Ltd Therapeutic use of P75NTR neurotrophin binding protein
GB201504691D0 (en) * 2015-03-19 2015-05-06 Levicept Ltd Fusion protein
EP3711772A1 (fr) 2019-03-20 2020-09-23 Oslo Universitetssykehus HF Protéines recombinantes et protéines de fusion
CN113456799A (zh) * 2020-12-25 2021-10-01 苏州澳宗生物科技有限公司 一种p75ECD在制备用于调节疼痛的药物中的应用
CN112851794B (zh) * 2021-02-04 2023-05-23 苏州铂维生物科技有限公司 一种基于cd271的抗原表位及其应用
US11608371B1 (en) * 2021-10-21 2023-03-21 Petmedix Ltd Therapeutic molecules
CA3236019A1 (fr) * 2021-10-21 2023-04-27 Petmedix Ltd Proteines comprenant le domaine extracellulaire de p75ntr

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9022648D0 (en) 1990-10-18 1990-11-28 Charing Cross Sunley Research Polypeptide and its use
FR2686900B1 (fr) * 1992-01-31 1995-07-21 Rhone Poulenc Rorer Sa Nouveaux polypeptides ayant une activite de stimulation des colonies de granulocytes, leur preparation et compositions pharmaceutiques les contenant.
US7217798B2 (en) 2003-10-15 2007-05-15 Pdl Biopharma, Inc. Alteration of Fc-fusion protein serum half-lives by mutagenesis
US7569364B2 (en) 2002-12-24 2009-08-04 Pfizer Inc. Anti-NGF antibodies and methods using same
US9498530B2 (en) 2002-12-24 2016-11-22 Rinat Neuroscience Corp. Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
JP2008528006A (ja) * 2005-01-28 2008-07-31 アポロ ライフ サイエンシズ リミテッド 分子およびそのキメラ分子
WO2007026567A1 (fr) 2005-08-30 2007-03-08 National University Corporation Chiba University AGENT ANALGÉSIQUE COMPRENANT UN INHIBITEUR p75NTR EN TANT QU’INGRÉDIENT ACTIF
US20070243132A1 (en) * 2005-12-22 2007-10-18 Apollo Life Sciences Limited Transdermal delivery of pharmaceutical agents
GB0717985D0 (en) * 2007-07-20 2007-10-24 Asterion Ltd Growth hormone fusion proteins
US8309088B2 (en) 2007-08-10 2012-11-13 Regeneron Pharmaceuticals, Inc. Method of treating osteoarthritis with an antibody to NGF
US20100061981A1 (en) 2008-08-15 2010-03-11 The Salk Institute For Biological Studies p75NTR MEDIATES EPHRIN-A REVERSE SIGNALING
CA2787099A1 (fr) * 2009-03-30 2010-10-14 Anice C. Lowen Polypeptides d'hemagglutinine du virus de l'influenza renfermant des domaines souches, vaccins et utilisations associees
CA2777717C (fr) * 2009-10-15 2021-05-25 Genentech, Inc. Facteurs de croissance chimeriques des fibroblastes avec specificite de recepteur modifiee
CN102770458A (zh) * 2009-12-02 2012-11-07 阿塞勒隆制药公司 用于增加Fc融合蛋白的血清半寿期的组合物和方法
CN102233128B (zh) 2010-11-26 2013-04-17 王延江 一种p75NTR-ECD在防治阿尔茨海默病药物中应用
ITRM20110024A1 (it) 2011-01-24 2012-07-25 Consiglio Nazionale Ricerche Uso di antagonisti del recettore p75ntr e/o di agonisti del recettore trka per il trattamento delle malattie infiammatorie croniche.
US20130078250A1 (en) * 2011-08-23 2013-03-28 Oliver Ast Bispecific t cell activating antigen binding molecules
TWI476001B (zh) * 2011-12-26 2015-03-11 Ind Tech Res Inst 三倍體Fc融合蛋白及其用途
CN102586313A (zh) 2012-03-05 2012-07-18 中国人民解放军第三军医大学野战外科研究所 p75NTR-ED-Fc融合蛋白的制备方法及其在损伤中枢神经再生与功能恢复中的应用
NZ628685A (en) * 2012-03-14 2017-12-22 Levicept Ltd Therapeutic use of p75ntr neurotrophin binding protein
EP2674439B1 (fr) * 2012-06-13 2017-02-01 Rottapharm Biotech S.r.l. Anticorps anti-TrkA, dérivés et utilisations associés
GB201316592D0 (en) * 2013-09-18 2013-10-30 Levicept Ltd Fusion protein
GB201412748D0 (en) 2014-07-17 2014-09-03 Levicept Ltd Therapeutic use of P75NTR neurotrophin binding protein
GB201504691D0 (en) 2015-03-19 2015-05-06 Levicept Ltd Fusion protein

Also Published As

Publication number Publication date
KR102205633B1 (ko) 2021-01-20
US10988526B2 (en) 2021-04-27
AU2014322842A1 (en) 2016-04-07
TR201903490T4 (tr) 2019-03-21
CA2924410A1 (fr) 2015-03-26
BR112016006113A2 (pt) 2017-09-26
EP3046934A1 (fr) 2016-07-27
PL3046934T3 (pl) 2019-05-31
EP3046934B1 (fr) 2018-12-12
CN105873943B (zh) 2023-04-07
KR20160058872A (ko) 2016-05-25
AU2014322842B2 (en) 2018-08-16
JP7357088B2 (ja) 2023-10-05
WO2015040398A1 (fr) 2015-03-26
JP2016531590A (ja) 2016-10-13
JP6681834B2 (ja) 2020-04-15
JP2022068253A (ja) 2022-05-09
IL244588B (en) 2019-12-31
DK3046934T3 (en) 2019-04-08
CA2924410C (fr) 2023-01-24
HRP20190434T1 (hr) 2019-04-19
NZ718044A (en) 2020-07-31
US20180273603A1 (en) 2018-09-27
ES2714694T3 (es) 2019-05-29
PT3046934T (pt) 2019-03-25
SI3046934T1 (sl) 2019-04-30
HUE043273T2 (hu) 2019-08-28
US20160222082A1 (en) 2016-08-04
EA037416B1 (ru) 2021-03-25
JP2020062011A (ja) 2020-04-23
IL244588A0 (en) 2016-04-21
CN105873943A (zh) 2016-08-17
RS58463B1 (sr) 2019-04-30
US9873728B2 (en) 2018-01-23
MX2016003530A (es) 2016-10-13
GB201316592D0 (en) 2013-10-30
EA201690469A1 (ru) 2016-12-30
LT3046934T (lt) 2019-03-25
US20210238256A1 (en) 2021-08-05
CY1121347T1 (el) 2020-05-29

Similar Documents

Publication Publication Date Title
IL284301A (en) Heterodimeric proteins
IL281703A (en) New heterodimeric proteins
EP2895819A4 (fr) Fusion de capteurs
EP2943512A4 (fr) Anticorps bovins de fusion
EP2968551A4 (fr) Protéines de fusion et procédés correspondants
HRP20190434T1 (hr) Fuzijski protein
HK1216159A1 (zh) 治療性融合蛋白
EP2992992A4 (fr) Joint à différents matériaux
HK1220903A1 (zh) 軟骨結合型融合蛋白
HK1231494A1 (zh) 殺蟲融合蛋白改進
EP2969009A4 (fr) Protéines de fusion de fc modifiées
GB201308057D0 (en) Protein
GB201401955D0 (en) Protein
GB201304973D0 (en) Recombinant protein
GB201314945D0 (en) Protein crystals
GB201304115D0 (en) Fusion ploypeptide
GB201302031D0 (en) Protein
GB201302030D0 (en) Protein
GB201309812D0 (en) MK-V fusion system
GB201300381D0 (en) Peptides