SI3046934T1 - Fuzijski protein - Google Patents

Fuzijski protein

Info

Publication number
SI3046934T1
SI3046934T1 SI201431067T SI201431067T SI3046934T1 SI 3046934 T1 SI3046934 T1 SI 3046934T1 SI 201431067 T SI201431067 T SI 201431067T SI 201431067 T SI201431067 T SI 201431067T SI 3046934 T1 SI3046934 T1 SI 3046934T1
Authority
SI
Slovenia
Prior art keywords
fusion protein
fusion
protein
Prior art date
Application number
SI201431067T
Other languages
English (en)
Inventor
Simon Westbrook
Original Assignee
Levicept Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Levicept Ltd. filed Critical Levicept Ltd.
Publication of SI3046934T1 publication Critical patent/SI3046934T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2807Headache; Migraine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2842Pain, e.g. neuropathic pain, psychogenic pain

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Epidemiology (AREA)
SI201431067T 2013-09-18 2014-09-18 Fuzijski protein SI3046934T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1316592.3A GB201316592D0 (en) 2013-09-18 2013-09-18 Fusion protein
PCT/GB2014/052833 WO2015040398A1 (en) 2013-09-18 2014-09-18 Fusion protein
EP14772194.8A EP3046934B1 (en) 2013-09-18 2014-09-18 Fusion protein

Publications (1)

Publication Number Publication Date
SI3046934T1 true SI3046934T1 (sl) 2019-04-30

Family

ID=49552839

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201431067T SI3046934T1 (sl) 2013-09-18 2014-09-18 Fuzijski protein

Country Status (25)

Country Link
US (3) US9873728B2 (sl)
EP (1) EP3046934B1 (sl)
JP (3) JP6681834B2 (sl)
KR (1) KR102205633B1 (sl)
CN (1) CN105873943B (sl)
AU (1) AU2014322842B2 (sl)
CA (1) CA2924410C (sl)
CY (1) CY1121347T1 (sl)
DK (1) DK3046934T3 (sl)
EA (1) EA037416B1 (sl)
ES (1) ES2714694T3 (sl)
GB (1) GB201316592D0 (sl)
HR (1) HRP20190434T1 (sl)
HU (1) HUE043273T2 (sl)
IL (1) IL244588B (sl)
LT (1) LT3046934T (sl)
MX (1) MX2016003530A (sl)
NZ (1) NZ718044A (sl)
PL (1) PL3046934T3 (sl)
PT (1) PT3046934T (sl)
RS (1) RS58463B1 (sl)
SG (1) SG11201602068QA (sl)
SI (1) SI3046934T1 (sl)
TR (1) TR201903490T4 (sl)
WO (1) WO2015040398A1 (sl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201705725XA (en) 2012-03-14 2017-08-30 Levicept Ltd Therapeutic use of p75ntr neurotrophin binding protein
GB201316592D0 (en) * 2013-09-18 2013-10-30 Levicept Ltd Fusion protein
GB201412748D0 (en) 2014-07-17 2014-09-03 Levicept Ltd Therapeutic use of P75NTR neurotrophin binding protein
GB201504691D0 (en) * 2015-03-19 2015-05-06 Levicept Ltd Fusion protein
EP3711772A1 (en) 2019-03-20 2020-09-23 Oslo Universitetssykehus HF Recombinant proteins and fusion proteins
CN113456799A (zh) * 2020-12-25 2021-10-01 苏州澳宗生物科技有限公司 一种p75ECD在制备用于调节疼痛的药物中的应用
CN112851794B (zh) * 2021-02-04 2023-05-23 苏州铂维生物科技有限公司 一种基于cd271的抗原表位及其应用
US11608371B1 (en) 2021-10-21 2023-03-21 Petmedix Ltd Therapeutic molecules
WO2023067358A1 (en) * 2021-10-21 2023-04-27 Petmedix Ltd Proteins comprising the extracellular domain of p75ntr

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9022648D0 (en) 1990-10-18 1990-11-28 Charing Cross Sunley Research Polypeptide and its use
FR2686900B1 (fr) * 1992-01-31 1995-07-21 Rhone Poulenc Rorer Sa Nouveaux polypeptides ayant une activite de stimulation des colonies de granulocytes, leur preparation et compositions pharmaceutiques les contenant.
US7217798B2 (en) 2003-10-15 2007-05-15 Pdl Biopharma, Inc. Alteration of Fc-fusion protein serum half-lives by mutagenesis
US9498530B2 (en) 2002-12-24 2016-11-22 Rinat Neuroscience Corp. Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
US7569364B2 (en) 2002-12-24 2009-08-04 Pfizer Inc. Anti-NGF antibodies and methods using same
US20090232808A1 (en) * 2005-01-28 2009-09-17 Apollo Life Sciences Limited Molecules and chimeric molecules thereof
JPWO2007026567A1 (ja) 2005-08-30 2009-03-05 国立大学法人 千葉大学 p75NTR阻害剤を有効成分として含有する鎮痛剤
US20070243132A1 (en) * 2005-12-22 2007-10-18 Apollo Life Sciences Limited Transdermal delivery of pharmaceutical agents
GB0717985D0 (en) * 2007-07-20 2007-10-24 Asterion Ltd Growth hormone fusion proteins
US8309088B2 (en) 2007-08-10 2012-11-13 Regeneron Pharmaceuticals, Inc. Method of treating osteoarthritis with an antibody to NGF
US20100061981A1 (en) 2008-08-15 2010-03-11 The Salk Institute For Biological Studies p75NTR MEDIATES EPHRIN-A REVERSE SIGNALING
WO2010117786A1 (en) * 2009-03-30 2010-10-14 Mount Sinai School Of Medicine Of New York University Influenza virus vaccines and uses thereof
US8535912B2 (en) * 2009-10-15 2013-09-17 Genentech, Inc. Chimeric fibroblast growth factors with altered receptor specificity
US8722615B2 (en) * 2009-12-02 2014-05-13 Acceleron Pharma, Inc. Compositions and methods for increasing serum half-life
CN102233128B (zh) 2010-11-26 2013-04-17 王延江 一种p75NTR-ECD在防治阿尔茨海默病药物中应用
ITRM20110024A1 (it) 2011-01-24 2012-07-25 Consiglio Nazionale Ricerche Uso di antagonisti del recettore p75ntr e/o di agonisti del recettore trka per il trattamento delle malattie infiammatorie croniche.
US20130078250A1 (en) * 2011-08-23 2013-03-28 Oliver Ast Bispecific t cell activating antigen binding molecules
TWI476001B (zh) * 2011-12-26 2015-03-11 Ind Tech Res Inst 三倍體Fc融合蛋白及其用途
CN102586313A (zh) 2012-03-05 2012-07-18 中国人民解放军第三军医大学野战外科研究所 p75NTR-ED-Fc融合蛋白的制备方法及其在损伤中枢神经再生与功能恢复中的应用
SG10201705725XA (en) * 2012-03-14 2017-08-30 Levicept Ltd Therapeutic use of p75ntr neurotrophin binding protein
EP2674439B1 (en) * 2012-06-13 2017-02-01 Rottapharm Biotech S.r.l. Anti-TrkA antibodies, derivatives and uses thereof
GB201316592D0 (en) * 2013-09-18 2013-10-30 Levicept Ltd Fusion protein
GB201412748D0 (en) * 2014-07-17 2014-09-03 Levicept Ltd Therapeutic use of P75NTR neurotrophin binding protein
GB201504691D0 (en) 2015-03-19 2015-05-06 Levicept Ltd Fusion protein

Also Published As

Publication number Publication date
CN105873943B (zh) 2023-04-07
HUE043273T2 (hu) 2019-08-28
EA037416B1 (ru) 2021-03-25
KR20160058872A (ko) 2016-05-25
TR201903490T4 (tr) 2019-03-21
DK3046934T3 (en) 2019-04-08
IL244588B (en) 2019-12-31
IL244588A0 (en) 2016-04-21
PL3046934T3 (pl) 2019-05-31
US9873728B2 (en) 2018-01-23
JP7357088B2 (ja) 2023-10-05
RS58463B1 (sr) 2019-04-30
JP6681834B2 (ja) 2020-04-15
HRP20190434T1 (hr) 2019-04-19
JP2020062011A (ja) 2020-04-23
JP2022068253A (ja) 2022-05-09
CA2924410A1 (en) 2015-03-26
CA2924410C (en) 2023-01-24
EA201690469A1 (ru) 2016-12-30
US20180273603A1 (en) 2018-09-27
NZ718044A (en) 2020-07-31
MX2016003530A (es) 2016-10-13
US20210238256A1 (en) 2021-08-05
SG11201602068QA (en) 2016-04-28
ES2714694T3 (es) 2019-05-29
JP2016531590A (ja) 2016-10-13
KR102205633B1 (ko) 2021-01-20
US20160222082A1 (en) 2016-08-04
EP3046934B1 (en) 2018-12-12
EP3046934A1 (en) 2016-07-27
AU2014322842A1 (en) 2016-04-07
CY1121347T1 (el) 2020-05-29
LT3046934T (lt) 2019-03-25
BR112016006113A2 (pt) 2017-09-26
AU2014322842B2 (en) 2018-08-16
WO2015040398A1 (en) 2015-03-26
PT3046934T (pt) 2019-03-25
US10988526B2 (en) 2021-04-27
GB201316592D0 (en) 2013-10-30
CN105873943A (zh) 2016-08-17

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