SG11201507681PA - Abiraterone acetate formulation - Google Patents

Abiraterone acetate formulation

Info

Publication number
SG11201507681PA
SG11201507681PA SG11201507681PA SG11201507681PA SG11201507681PA SG 11201507681P A SG11201507681P A SG 11201507681PA SG 11201507681P A SG11201507681P A SG 11201507681PA SG 11201507681P A SG11201507681P A SG 11201507681PA SG 11201507681P A SG11201507681P A SG 11201507681PA
Authority
SG
Singapore
Prior art keywords
abiraterone acetate
acetate formulation
formulation
abiraterone
acetate
Prior art date
Application number
SG11201507681PA
Other languages
English (en)
Inventor
H William Bosch
Marck Norret
Paul Nemeth
Matt Callahan
Original Assignee
Iceutica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iceutica Inc filed Critical Iceutica Inc
Publication of SG11201507681PA publication Critical patent/SG11201507681PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28Antiandrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C19/00Other disintegrating devices or methods
    • B02C19/16Mills provided with vibrators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201507681PA 2013-03-15 2014-03-17 Abiraterone acetate formulation SG11201507681PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361789141P 2013-03-15 2013-03-15
US201361883941P 2013-09-27 2013-09-27
PCT/US2014/030642 WO2014145813A1 (en) 2013-03-15 2014-03-17 Abiraterone acetate formulation

Publications (1)

Publication Number Publication Date
SG11201507681PA true SG11201507681PA (en) 2015-10-29

Family

ID=51538105

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201507681PA SG11201507681PA (en) 2013-03-15 2014-03-17 Abiraterone acetate formulation
SG10201709400VA SG10201709400VA (en) 2013-03-15 2014-03-17 Abiraterone acetate formulation

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201709400VA SG10201709400VA (en) 2013-03-15 2014-03-17 Abiraterone acetate formulation

Country Status (20)

Country Link
US (3) US20140287039A1 (zh)
EP (2) EP2969227B1 (zh)
JP (4) JP2016514707A (zh)
KR (3) KR20160023641A (zh)
CN (2) CN110604721B (zh)
AU (2) AU2014232508C1 (zh)
BR (1) BR112015023629A8 (zh)
CA (1) CA2907415C (zh)
CL (1) CL2015002787A1 (zh)
ES (1) ES2741800T3 (zh)
HK (2) HK1219457A1 (zh)
IL (1) IL241612B (zh)
MX (1) MX2015013247A (zh)
NZ (1) NZ712350A (zh)
PL (1) PL2969227T3 (zh)
RU (1) RU2732136C2 (zh)
SG (2) SG11201507681PA (zh)
TW (2) TWI686212B (zh)
WO (1) WO2014145813A1 (zh)
ZA (1) ZA201507209B (zh)

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EP3080141A1 (en) 2013-12-12 2016-10-19 Basf Se Solid form of abiraterone acetate
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AU2015317466A1 (en) * 2014-09-18 2017-02-23 Sun Pharma Global Fze Abiraterone acetate formulation and methods of use
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UA123538C2 (uk) 2014-12-05 2021-04-21 Араґон Фармасьютікалз, Інк. Протиракові композиції
HUP1500055A1 (hu) 2015-02-09 2016-08-29 Druggability Technologies Ip Holdco Ltd Abirateron acetát komplexei, eljárás elõállításukra, és az azokat tartalmazó gyógyászati készítmények
US10722527B2 (en) * 2015-04-10 2020-07-28 Capsugel Belgium Nv Abiraterone acetate lipid formulations
KR20180104662A (ko) 2016-02-04 2018-09-21 신알엑스 파마, 엘엘씨 장애 치료를 위한 중수소화된 돔페리돈 조성물 및 방법
MX2018009866A (es) 2016-02-16 2018-11-09 Gx Tech Canada Ltd Depresor de aleta sustentadora de cinta.
MA45090A (fr) * 2016-06-03 2021-04-28 Aragon Pharmaceuticals Inc Compositions anticancéreuses
KR20200021451A (ko) * 2017-04-07 2020-02-28 엠에이에이 래보러토리스, 인코포레이티드 치료제의 용해도 및 생체이용률을 향상시키는 방법
US11364226B2 (en) 2017-06-30 2022-06-21 Cinrx Pharma, Llc Deuterated domperidone compositions, methods, and preparation
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WO2019186444A1 (en) * 2018-03-29 2019-10-03 Leiutis Pharmaceuticals Pvt, Ltd Oral liquid formulations of abiraterone
EP3826770A4 (en) * 2018-07-24 2022-05-18 Camx Power, L.L.C. ADDITIVE AND DRY GRINDING PROCESS
HU231297B1 (hu) * 2018-07-31 2022-09-28 Richter Gedeon Nyrt Stabil gyógyszerkészítmények és eljárás az előállításukra
KR20210080350A (ko) 2018-07-31 2021-06-30 마이크로비온 코포레이션 상처 치료를 위한 비스무트-티올 조성물 및 방법
WO2020073126A1 (en) 2018-10-09 2020-04-16 Gx Technology Canada Ltd. Modular foil system for towed marine array
WO2020151633A1 (en) * 2019-01-25 2020-07-30 Shenzhen Pharmacin Co., Ltd. Pharmaceutical compositions
AU2020232706A1 (en) 2019-03-06 2021-09-16 Propella Therapeutics, Inc. Abiraterone prodrugs
CN113133983B (zh) * 2020-01-20 2023-12-12 鲁南制药集团股份有限公司 一种治疗前列腺癌的药物组合物
EP3944860A1 (en) 2020-07-30 2022-02-02 Galenicum Health S.L.U. Abiraterone for use in a method of treating cancer
CN112933053B (zh) * 2021-01-29 2022-11-25 中国药科大学 一种醋酸阿比特龙的纳米晶体及其制剂和制备方法
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Also Published As

Publication number Publication date
TWI731321B (zh) 2021-06-21
EP3578266B1 (en) 2024-06-19
CL2015002787A1 (es) 2016-05-13
AU2018241103A1 (en) 2018-10-25
RU2732136C2 (ru) 2020-09-11
KR20190141270A (ko) 2019-12-23
TW201513896A (zh) 2015-04-16
ZA201507209B (en) 2016-12-21
KR102121404B1 (ko) 2020-06-11
JP2021008521A (ja) 2021-01-28
ES2741800T3 (es) 2020-02-12
TW201943408A (zh) 2019-11-16
EP2969227A4 (en) 2016-12-07
WO2014145813A1 (en) 2014-09-18
US20170354665A1 (en) 2017-12-14
EP2969227A1 (en) 2016-01-20
TWI686212B (zh) 2020-03-01
EP2969227B1 (en) 2019-05-08
US20160067265A1 (en) 2016-03-10
RU2015144285A (ru) 2017-04-24
JP2023103410A (ja) 2023-07-26
NZ712350A (en) 2020-08-28
US20140287039A1 (en) 2014-09-25
CN110604721A (zh) 2019-12-24
SG10201709400VA (en) 2018-01-30
JP2018135351A (ja) 2018-08-30
JP7320485B2 (ja) 2023-08-03
BR112015023629A8 (pt) 2023-04-11
MX2015013247A (es) 2016-11-25
AU2014232508A1 (en) 2015-10-08
HK1219457A1 (zh) 2017-04-07
JP2016514707A (ja) 2016-05-23
KR20180021932A (ko) 2018-03-05
CN105246598A (zh) 2016-01-13
CA2907415C (en) 2022-04-05
EP3578266A1 (en) 2019-12-11
AU2014232508B2 (en) 2018-07-12
BR112015023629A2 (pt) 2017-07-18
AU2014232508C1 (en) 2023-01-19
AU2018241103B2 (en) 2020-08-13
CN110604721B (zh) 2022-02-08
PL2969227T3 (pl) 2019-12-31
CN105246598B (zh) 2019-09-13
IL241612B (en) 2020-03-31
CA2907415A1 (en) 2014-09-18
KR20160023641A (ko) 2016-03-03
HK1220162A1 (zh) 2017-04-28

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