SG11201503215XA - Novel method for treating spinal cord injury using hmgb1 fragment - Google Patents
Novel method for treating spinal cord injury using hmgb1 fragmentInfo
- Publication number
- SG11201503215XA SG11201503215XA SG11201503215XA SG11201503215XA SG11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA
- Authority
- SG
- Singapore
- Prior art keywords
- spinal cord
- novel method
- cord injury
- treating spinal
- hmgb1 fragment
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title 1
- 208000020431 spinal cord injury Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012235786 | 2012-10-25 | ||
| PCT/JP2013/078759 WO2014065348A1 (ja) | 2012-10-25 | 2013-10-24 | Hmgb1断片を利用した脊髄の損傷に対する新規治療法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201503215XA true SG11201503215XA (en) | 2015-06-29 |
Family
ID=50544721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201503215XA SG11201503215XA (en) | 2012-10-25 | 2013-10-24 | Novel method for treating spinal cord injury using hmgb1 fragment |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9688733B2 (ja) |
| EP (1) | EP2913059B1 (ja) |
| JP (1) | JP6253590B2 (ja) |
| KR (1) | KR102146822B1 (ja) |
| CN (1) | CN104955470B (ja) |
| AU (1) | AU2013335685B2 (ja) |
| BR (1) | BR112015008745B1 (ja) |
| CA (1) | CA2889299C (ja) |
| DK (1) | DK2913059T3 (ja) |
| ES (1) | ES2673861T3 (ja) |
| HK (2) | HK1212888A1 (ja) |
| MX (1) | MX365899B (ja) |
| PL (1) | PL2913059T3 (ja) |
| RU (1) | RU2649069C2 (ja) |
| SG (1) | SG11201503215XA (ja) |
| TR (1) | TR201807769T4 (ja) |
| WO (1) | WO2014065348A1 (ja) |
| ZA (1) | ZA201502829B (ja) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2284255B1 (en) | 2008-04-30 | 2017-10-18 | Genomix Co., Ltd. | Method for collecting functional cells in vivo with high efficiency |
| ES2788394T3 (es) | 2011-04-26 | 2020-10-21 | Stemrim Inc | Péptido para inducir regeneración de tejido y uso del mismo |
| EP2913058B1 (en) | 2012-10-25 | 2017-12-20 | Genomix Co., Ltd. | Novel method for treating cardiac infarction using hmgb1 fragment |
| BR112019014921A2 (pt) | 2017-01-27 | 2020-03-31 | StemRIM Inc. | Agente terapêutico para miocardiopatia, infarto antigo do miocárdio e insuficiência cardíaca crônica |
| JPWO2019107530A1 (ja) * | 2017-12-01 | 2020-11-26 | 株式会社ステムリム | 炎症性腸疾患の治療薬 |
| US20210024594A1 (en) | 2018-02-08 | 2021-01-28 | StemRIM Inc. | Therapeutic Agent for Psoriasis |
| WO2020071520A1 (ja) * | 2018-10-05 | 2020-04-09 | 株式会社ステムリム | 間葉系幹細胞の動員活性を有するペプチド |
| JP7448126B2 (ja) * | 2018-10-25 | 2024-03-12 | 国立大学法人大阪大学 | 軟骨疾患の治療薬 |
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| US5658894A (en) | 1989-04-23 | 1997-08-19 | The Trustees Of The University Of Pennsylvania | Compositions for inhibiting restenosis |
| US5661127A (en) | 1995-05-01 | 1997-08-26 | The Regents Of The University Of California | Peptide compositions with growth factor-like activity |
| JP3018313B2 (ja) * | 1996-02-23 | 2000-03-13 | 雪印乳業株式会社 | 骨形成促進及び骨吸収防止剤 |
| US20040031072A1 (en) | 1999-05-06 | 2004-02-12 | La Rosa Thomas J. | Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement |
| BR0012787A (pt) | 1999-07-28 | 2002-07-30 | Univ Leland Stanford Junior | Agonistas de receptor de nicotina no recrutamento de célula tronco e de célula progenitora |
| EP1114862A3 (de) | 1999-11-17 | 2003-08-06 | Switch Biotech Aktiengesellschaft | Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen |
| ATE373078T1 (de) | 2000-02-24 | 2007-09-15 | Xcyte Therapies Inc | Gleichzeitige stimulation und konzentration von zellen |
| JP3421741B2 (ja) | 2000-05-18 | 2003-06-30 | 筑波大学長 | 人工骨髄、血球細胞の増殖方法 |
| US20040191246A1 (en) | 2003-02-26 | 2004-09-30 | Connelly Patrick R. | Process for in vivo treatment of specific biological targets in bodily fluid |
| ITMI20010562A1 (it) | 2001-03-16 | 2002-09-16 | Marco E Bianchi | Inibitori o antagonisti della proteina hmg1 per il trattamento di disordini vascolari |
| DE10121254A1 (de) | 2001-04-30 | 2002-11-07 | Switch Biotech Ag | MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind |
| EP1390058A2 (en) | 2001-04-30 | 2004-02-25 | Switch Biotech Aktiengesellschaft | Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances |
| US7220723B2 (en) | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
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| JP2005512507A (ja) | 2001-05-15 | 2005-05-12 | ノース・ショア−ロング・アイランド・ジューイッシュ・リサーチ・インスティテュート | 抗炎症剤としてのｈｍｇフラグメントの使用 |
| ITMI20011986A1 (it) | 2001-09-25 | 2003-03-25 | San Raffaele Centro Fond | Metodo e composizione per l'attivazione di cellule presentanti l'antigene |
| WO2003043651A1 (en) | 2001-11-19 | 2003-05-30 | Kyowa Hakko Kogyo Co., Ltd. | Drug mobilizing pluripotent stem cells from tissue into peripheral blood |
| KR101083454B1 (ko) | 2001-12-07 | 2011-11-16 | 사이토리 테라퓨틱스, 인크. | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
| EP1519957B1 (en) | 2002-07-03 | 2009-03-04 | Fondazione Centro San Raffaele Del Monte Tabor | Use of hmgb1 in the treatment of tissue damage and/or to promote tissue repair |
| WO2004004770A1 (en) | 2002-07-05 | 2004-01-15 | Universite Laval | Chemotactic factor inhibitor for modulating inflammatory reactions |
| GB0226251D0 (en) | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
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| WO2004061456A2 (de) | 2003-01-03 | 2004-07-22 | Alcedo Biotech Gmbh | Verwendungen von hmgb, hmgn, hmga proteinen |
| CA2520515C (en) | 2003-03-28 | 2012-08-28 | Universite Laval | S100 protein as neutrophil activator for alleviating neutropenia in cancer treatment |
| US20050014255A1 (en) | 2003-05-29 | 2005-01-20 | Board Of Regents, The University Of Texas System | Stem cells for clinical and commercial uses |
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| ITRM20040058A1 (it) | 2004-02-03 | 2004-05-03 | Marco E Bianchi | Inibitori ed antagonisti di hmgb1 in grado di regolare la proliferazione delle cellule muscolari lisce ed endoteliali. |
| EP1768693A1 (en) | 2004-07-20 | 2007-04-04 | Provincia Italiana Della Congregazione Dei Figli Dell'Immacolata Concezione - Istituto Dermopatico Dell'Immacolata | Use of hmgb1 for wound healing |
| MX2007001155A (es) | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
| AU2005279308B2 (en) | 2004-09-03 | 2012-05-03 | Creabilis Therapeutics S.R.L. | Protease resistant human and non-human HMGB1 Box-A mutants and their therapeutic/diagnostic use |
| KR100593397B1 (ko) | 2004-10-27 | 2006-06-28 | 한국원자력연구소 | 중배엽 줄기세포 및/또는 ｐ 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제 |
| WO2006047820A1 (en) | 2004-11-01 | 2006-05-11 | Newsouth Innovations Pty Limited | Use of calgranulin a and b in the promotion and inhibition of mineralized tissue formation |
| ITRM20050032A1 (it) | 2005-01-21 | 2006-07-22 | Marco E Bianchi | Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica. |
| US9782439B2 (en) | 2005-01-27 | 2017-10-10 | Japan Health Sciences Foundation | Cell sheet containing mesenchymal stem cells |
| CN101146559B (zh) | 2005-03-23 | 2012-09-05 | 生物安全股份有限公司 | 用于再生医学的收集、处理和移植包括成人干细胞的细胞亚群的集成系统 |
| WO2006114805A2 (en) | 2005-04-28 | 2006-11-02 | Fondazione Centro San Raffaele Del Monte Tabor | Use of hmgb2 and hmgb3 proteins for medical applications |
| WO2007015546A1 (ja) | 2005-08-04 | 2007-02-08 | Genomix Co., Ltd | 間葉系幹細胞誘導剤及び組織再生促進剤並びに間葉系幹細胞の調製方法 |
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| EP2284255B1 (en) | 2008-04-30 | 2017-10-18 | Genomix Co., Ltd. | Method for collecting functional cells in vivo with high efficiency |
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| CA2777663A1 (en) * | 2009-10-16 | 2011-04-21 | University Of Medicine And Dentistry Of New Jersey | Method for treating chronic nerve tissue injury using a cell therapy strategy |
| CN104825491A (zh) * | 2009-10-28 | 2015-08-12 | 吉诺米克斯股份有限公司 | 利用骨髓间充质干细胞和/或多能干细胞的血中动员的组织再生促进剂 |
| ES2788394T3 (es) | 2011-04-26 | 2020-10-21 | Stemrim Inc | Péptido para inducir regeneración de tejido y uso del mismo |
| CN102443064A (zh) | 2011-11-03 | 2012-05-09 | 刘誉 | 一种基于凝血酶活性的双靶向作用的嵌合多肽及其应用 |
| EP2913058B1 (en) | 2012-10-25 | 2017-12-20 | Genomix Co., Ltd. | Novel method for treating cardiac infarction using hmgb1 fragment |
-
2013
- 2013-10-24 KR KR1020157013591A patent/KR102146822B1/ko active IP Right Grant
- 2013-10-24 AU AU2013335685A patent/AU2013335685B2/en active Active
- 2013-10-24 CN CN201380067951.4A patent/CN104955470B/zh active Active
- 2013-10-24 ES ES13849823.3T patent/ES2673861T3/es active Active
- 2013-10-24 TR TR2018/07769T patent/TR201807769T4/tr unknown
- 2013-10-24 US US14/436,920 patent/US9688733B2/en active Active
- 2013-10-24 JP JP2014543335A patent/JP6253590B2/ja active Active
- 2013-10-24 PL PL13849823T patent/PL2913059T3/pl unknown
- 2013-10-24 CA CA2889299A patent/CA2889299C/en active Active
- 2013-10-24 SG SG11201503215XA patent/SG11201503215XA/en unknown
- 2013-10-24 BR BR112015008745-0A patent/BR112015008745B1/pt active IP Right Grant
- 2013-10-24 DK DK13849823.3T patent/DK2913059T3/en active
- 2013-10-24 MX MX2015005253A patent/MX365899B/es active IP Right Grant
- 2013-10-24 EP EP13849823.3A patent/EP2913059B1/en active Active
- 2013-10-24 WO PCT/JP2013/078759 patent/WO2014065348A1/ja active Application Filing
- 2013-10-24 RU RU2015119523A patent/RU2649069C2/ru active
-
2015
- 2015-04-24 ZA ZA2015/02829A patent/ZA201502829B/en unknown
-
2016
- 2016-01-25 HK HK16100783.3A patent/HK1212888A1/zh unknown
- 2016-02-04 HK HK16101298.9A patent/HK1213201A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201502829B (en) | 2020-11-25 |
| BR112015008745B1 (pt) | 2022-08-02 |
| US20150274792A1 (en) | 2015-10-01 |
| HK1212888A1 (zh) | 2016-06-24 |
| CN104955470A (zh) | 2015-09-30 |
| EP2913059A4 (en) | 2016-03-30 |
| JP6253590B2 (ja) | 2017-12-27 |
| RU2649069C2 (ru) | 2018-04-02 |
| US9688733B2 (en) | 2017-06-27 |
| CA2889299C (en) | 2023-02-14 |
| WO2014065348A1 (ja) | 2014-05-01 |
| RU2015119523A (ru) | 2016-12-20 |
| TR201807769T4 (tr) | 2018-06-21 |
| KR20150102957A (ko) | 2015-09-09 |
| BR112015008745A2 (pt) | 2017-11-21 |
| JPWO2014065348A1 (ja) | 2016-09-08 |
| HK1213201A1 (zh) | 2016-06-30 |
| EP2913059B1 (en) | 2018-04-11 |
| AU2013335685B2 (en) | 2017-10-12 |
| ES2673861T3 (es) | 2018-06-26 |
| MX365899B (es) | 2019-06-19 |
| PL2913059T3 (pl) | 2018-09-28 |
| AU2013335685A1 (en) | 2015-05-14 |
| KR102146822B1 (ko) | 2020-08-21 |
| EP2913059A1 (en) | 2015-09-02 |
| CN104955470B (zh) | 2017-06-16 |
| MX2015005253A (es) | 2015-10-29 |
| CA2889299A1 (en) | 2014-05-01 |
| DK2913059T3 (en) | 2018-06-25 |
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