SG11201403814RA - Production of recombinant proteins with simple glycoforms - Google Patents
Production of recombinant proteins with simple glycoformsInfo
- Publication number
- SG11201403814RA SG11201403814RA SG11201403814RA SG11201403814RA SG11201403814RA SG 11201403814R A SG11201403814R A SG 11201403814RA SG 11201403814R A SG11201403814R A SG 11201403814RA SG 11201403814R A SG11201403814R A SG 11201403814RA SG 11201403814R A SG11201403814R A SG 11201403814RA
- Authority
- SG
- Singapore
- Prior art keywords
- production
- recombinant proteins
- simple glycoforms
- glycoforms
- recombinant
- Prior art date
Links
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01101—Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (2.4.1.101)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261585508P | 2012-01-11 | 2012-01-11 | |
| US201261636680P | 2012-04-22 | 2012-04-22 | |
| US201261720268P | 2012-10-30 | 2012-10-30 | |
| PCT/US2013/020947 WO2013106515A1 (en) | 2012-01-11 | 2013-01-10 | Production of recombinant proteins with simple glycoforms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201403814RA true SG11201403814RA (en) | 2014-10-30 |
Family
ID=48781886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201403814RA SG11201403814RA (en) | 2012-01-11 | 2013-01-10 | Production of recombinant proteins with simple glycoforms |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9376484B2 (ko) |
| EP (1) | EP2802654B1 (ko) |
| JP (3) | JP6262665B2 (ko) |
| KR (1) | KR102212865B1 (ko) |
| CN (2) | CN104245932A (ko) |
| BR (1) | BR112014016614B1 (ko) |
| ES (1) | ES2733248T3 (ko) |
| SG (1) | SG11201403814RA (ko) |
| WO (1) | WO2013106515A1 (ko) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2733248T3 (es) | 2012-01-11 | 2019-11-28 | Sigma Aldrich Co Llc | Producción de proteínas recombinantes con glicoformas simples |
| EP3736325A1 (en) * | 2014-03-04 | 2020-11-11 | Sigma Aldrich Co. LLC | Viral resistant cells and uses thereof |
| EP3230438A2 (en) | 2014-12-12 | 2017-10-18 | University of Copenhagen | N-glycosylation |
| CN105820246A (zh) * | 2015-01-07 | 2016-08-03 | 上海张江生物技术有限公司 | 一种新型重组抗TNFα嵌合单克隆抗体制备方法及用途 |
| US20190330601A1 (en) * | 2016-05-13 | 2019-10-31 | University Of Copenhagen | A cell-based array platform |
| US20200231633A1 (en) * | 2017-07-19 | 2020-07-23 | The Regents Of The University Of California | MGAT1-Deficient Cells for Production of Vaccines and Biopharmaceutical Products |
| US11624080B2 (en) | 2017-11-28 | 2023-04-11 | Danmarks Tekniske Universitet | Glycosylation of proteins |
| CN108588127A (zh) * | 2018-04-11 | 2018-09-28 | 上海药明生物技术有限公司 | 一种表达高甘露糖糖型的葡萄糖脑苷脂酶的细胞株及其制备方法和应用 |
| JP2023527109A (ja) * | 2020-04-23 | 2023-06-27 | ウーシー バイオロジクス アイルランド リミテッド | マンノース末端のｎ－グリカンを有する組換え糖タンパク質を生産する遺伝子改変細胞株 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5487994A (en) | 1992-04-03 | 1996-01-30 | The Johns Hopkins University | Insertion and deletion mutants of FokI restriction endonuclease |
| US5436150A (en) | 1992-04-03 | 1995-07-25 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease |
| US5356802A (en) | 1992-04-03 | 1994-10-18 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoites (FokI) restriction endonuclease |
| US6140466A (en) | 1994-01-18 | 2000-10-31 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| US6242568B1 (en) | 1994-01-18 | 2001-06-05 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| JP4118327B2 (ja) | 1994-08-20 | 2008-07-16 | ゲンダック・リミテッド | Ｄｎａ認識のための結合タンパク質におけるまたはそれに関連する改良 |
| GB9824544D0 (en) | 1998-11-09 | 1999-01-06 | Medical Res Council | Screening system |
| US5789538A (en) | 1995-02-03 | 1998-08-04 | Massachusetts Institute Of Technology | Zinc finger proteins with high affinity new DNA binding specificities |
| US5925523A (en) | 1996-08-23 | 1999-07-20 | President & Fellows Of Harvard College | Intraction trap assay, reagents and uses thereof |
| GB9703369D0 (en) | 1997-02-18 | 1997-04-09 | Lindqvist Bjorn H | Process |
| GB2338237B (en) | 1997-02-18 | 2001-02-28 | Actinova Ltd | In vitro peptide or protein expression library |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| US6410248B1 (en) | 1998-01-30 | 2002-06-25 | Massachusetts Institute Of Technology | General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites |
| JP4309051B2 (ja) | 1998-03-02 | 2009-08-05 | マサチューセッツ インスティテュート オブ テクノロジー | 改善したリンカーを有するポリジンクフィンガータンパク質 |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6794136B1 (en) | 2000-11-20 | 2004-09-21 | Sangamo Biosciences, Inc. | Iterative optimization in the design of binding proteins |
| AU2001263155A1 (en) | 2000-05-16 | 2001-11-26 | Massachusetts Institute Of Technology | Methods and compositions for interaction trap assays |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| EP1893756B1 (en) | 2005-06-08 | 2015-08-12 | The Regents of The University of California | Elimination of n-glycolylneuraminic acid from mammalian products for human use |
| WO2007014275A2 (en) | 2005-07-26 | 2007-02-01 | Sangamo Biosciences, Inc. | Targeted integration and expression of exogenous nucleic acid sequences |
| US20100247570A1 (en) * | 2006-11-13 | 2010-09-30 | Procell Corporation | High Mannose Glycoprotein Epitopes |
| US20100145032A1 (en) * | 2007-01-18 | 2010-06-10 | Suomen Punainen Risti, Veripalelu | Novel carbohydrate profile compositions from human cells and methods for analysis and modification thereof |
| JP2012502654A (ja) | 2008-09-19 | 2012-02-02 | エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ（エイ・スター） | チャイニーズハムスター卵巣細胞系 |
| US20110016546A1 (en) | 2008-12-04 | 2011-01-20 | Sigma-Aldrich Co. | Porcine genome editing with zinc finger nucleases |
| US20110030072A1 (en) * | 2008-12-04 | 2011-02-03 | Sigma-Aldrich Co. | Genome editing of immunodeficiency genes in animals |
| US20130164329A1 (en) | 2010-02-17 | 2013-06-27 | Alnylam Pharmaceuticals, Inc. | Cell-based methods and reagents |
| MX2013006234A (es) | 2011-01-06 | 2013-08-01 | Univ Johns Hopkins | Metodo para la produccion de glicoproteinas recombinantes con semivida en circulacion incrementada en celulas de mamifero. |
| ES2733248T3 (es) | 2012-01-11 | 2019-11-28 | Sigma Aldrich Co Llc | Producción de proteínas recombinantes con glicoformas simples |
-
2013
- 2013-01-10 ES ES13735783T patent/ES2733248T3/es active Active
- 2013-01-10 JP JP2014552284A patent/JP6262665B2/ja active Active
- 2013-01-10 WO PCT/US2013/020947 patent/WO2013106515A1/en active Application Filing
- 2013-01-10 CN CN201380005345.XA patent/CN104245932A/zh active Pending
- 2013-01-10 BR BR112014016614-5A patent/BR112014016614B1/pt active IP Right Grant
- 2013-01-10 CN CN201910526345.3A patent/CN110438083A/zh active Pending
- 2013-01-10 US US14/371,137 patent/US9376484B2/en active Active
- 2013-01-10 KR KR1020147017287A patent/KR102212865B1/ko active IP Right Grant
- 2013-01-10 EP EP13735783.6A patent/EP2802654B1/en active Active
- 2013-01-10 SG SG11201403814RA patent/SG11201403814RA/en unknown
-
2016
- 2016-06-02 US US15/171,977 patent/US9670271B2/en active Active
-
2017
- 2017-08-09 JP JP2017154341A patent/JP2018023379A/ja active Pending
-
2019
- 2019-12-20 JP JP2019230287A patent/JP2020072677A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018023379A (ja) | 2018-02-15 |
| US9670271B2 (en) | 2017-06-06 |
| JP2015503360A (ja) | 2015-02-02 |
| US20140349341A1 (en) | 2014-11-27 |
| BR112014016614A2 (pt) | 2020-10-27 |
| US20160272696A1 (en) | 2016-09-22 |
| KR20140111657A (ko) | 2014-09-19 |
| CN110438083A (zh) | 2019-11-12 |
| ES2733248T3 (es) | 2019-11-28 |
| CN104245932A (zh) | 2014-12-24 |
| JP6262665B2 (ja) | 2018-01-17 |
| US9376484B2 (en) | 2016-06-28 |
| BR112014016614B1 (pt) | 2022-02-01 |
| JP2020072677A (ja) | 2020-05-14 |
| EP2802654A1 (en) | 2014-11-19 |
| EP2802654B1 (en) | 2019-04-03 |
| EP2802654A4 (en) | 2015-11-04 |
| KR102212865B1 (ko) | 2021-02-05 |
| WO2013106515A1 (en) | 2013-07-18 |
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