SG11201403814RA - Production of recombinant proteins with simple glycoforms - Google Patents
Production of recombinant proteins with simple glycoformsInfo
- Publication number
- SG11201403814RA SG11201403814RA SG11201403814RA SG11201403814RA SG11201403814RA SG 11201403814R A SG11201403814R A SG 11201403814RA SG 11201403814R A SG11201403814R A SG 11201403814RA SG 11201403814R A SG11201403814R A SG 11201403814RA SG 11201403814R A SG11201403814R A SG 11201403814RA
- Authority
- SG
- Singapore
- Prior art keywords
- production
- recombinant proteins
- simple glycoforms
- glycoforms
- recombinant
- Prior art date
Links
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01101—Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (2.4.1.101)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261585508P | 2012-01-11 | 2012-01-11 | |
| US201261636680P | 2012-04-22 | 2012-04-22 | |
| US201261720268P | 2012-10-30 | 2012-10-30 | |
| PCT/US2013/020947 WO2013106515A1 (en) | 2012-01-11 | 2013-01-10 | Production of recombinant proteins with simple glycoforms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201403814RA true SG11201403814RA (en) | 2014-10-30 |
Family
ID=48781886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201403814RA SG11201403814RA (en) | 2012-01-11 | 2013-01-10 | Production of recombinant proteins with simple glycoforms |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9376484B2 (en) |
| EP (1) | EP2802654B1 (en) |
| JP (3) | JP6262665B2 (en) |
| KR (1) | KR102212865B1 (en) |
| CN (2) | CN104245932A (en) |
| BR (1) | BR112014016614B1 (en) |
| ES (1) | ES2733248T3 (en) |
| SG (1) | SG11201403814RA (en) |
| WO (1) | WO2013106515A1 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014016614B1 (en) | 2012-01-11 | 2022-02-01 | Sigma-Aldrich Co. Llc | METHODS FOR PRODUCING A CELL DEFICIENT IN MANOSIL (ALPHA-1,3-)-GLYCOPROTEIN BETA-1,2-NACETYL GLUCOSE-MINILTRANSFERASE I (MGAT1) AND PRODUCING A RECOMBINANT PROTEIN SHOWING ONE OR MORE TERMINAL MANNOSE RESIDUES |
| SG11201607038TA (en) * | 2014-03-04 | 2016-09-29 | Sigma Aldrich Co Llc | Viral resistant cells and uses thereof |
| WO2016091268A2 (en) * | 2014-12-12 | 2016-06-16 | University Of Copenhagen | N-glycosylation |
| CN105820246A (en) * | 2015-01-07 | 2016-08-03 | 上海张江生物技术有限公司 | Method for preparing novel recombinant anti-TNF alpha chimeric monoclonal antibody and application thereof |
| WO2017194699A1 (en) * | 2016-05-13 | 2017-11-16 | University Of Copenhagen | A cell-based array platform |
| US20200231633A1 (en) * | 2017-07-19 | 2020-07-23 | The Regents Of The University Of California | MGAT1-Deficient Cells for Production of Vaccines and Biopharmaceutical Products |
| US11624080B2 (en) | 2017-11-28 | 2023-04-11 | Danmarks Tekniske Universitet | Glycosylation of proteins |
| CN108588127A (en) * | 2018-04-11 | 2018-09-28 | 上海药明生物技术有限公司 | A kind of cell strain of glucocerebrosidase and its preparation method and application of expression high mannose sugar-type |
| CN115867644A (en) * | 2020-04-23 | 2023-03-28 | 上海药明生物技术有限公司 | Genetically modified cell lines producing recombinant glycoproteins with mannose-terminated N-glycans |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5356802A (en) | 1992-04-03 | 1994-10-18 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoites (FokI) restriction endonuclease |
| US5436150A (en) | 1992-04-03 | 1995-07-25 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease |
| US5487994A (en) | 1992-04-03 | 1996-01-30 | The Johns Hopkins University | Insertion and deletion mutants of FokI restriction endonuclease |
| US6242568B1 (en) | 1994-01-18 | 2001-06-05 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| US6140466A (en) | 1994-01-18 | 2000-10-31 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| GB9824544D0 (en) | 1998-11-09 | 1999-01-06 | Medical Res Council | Screening system |
| USRE45721E1 (en) | 1994-08-20 | 2015-10-06 | Gendaq, Ltd. | Relating to binding proteins for recognition of DNA |
| US5789538A (en) | 1995-02-03 | 1998-08-04 | Massachusetts Institute Of Technology | Zinc finger proteins with high affinity new DNA binding specificities |
| US5925523A (en) | 1996-08-23 | 1999-07-20 | President & Fellows Of Harvard College | Intraction trap assay, reagents and uses thereof |
| GB2338237B (en) | 1997-02-18 | 2001-02-28 | Actinova Ltd | In vitro peptide or protein expression library |
| GB9703369D0 (en) | 1997-02-18 | 1997-04-09 | Lindqvist Bjorn H | Process |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| US6410248B1 (en) | 1998-01-30 | 2002-06-25 | Massachusetts Institute Of Technology | General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites |
| CA2321938C (en) | 1998-03-02 | 2009-11-24 | Massachusetts Institute Of Technology | Poly zinc finger proteins with improved linkers |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6794136B1 (en) | 2000-11-20 | 2004-09-21 | Sangamo Biosciences, Inc. | Iterative optimization in the design of binding proteins |
| AU2001263155A1 (en) | 2000-05-16 | 2001-11-26 | Massachusetts Institute Of Technology | Methods and compositions for interaction trap assays |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| AU2006254862B2 (en) | 2005-06-08 | 2011-04-07 | The Regents Of The University Of California | Elimination of N-glycolylneuraminic acid from mammalian products for human use |
| CN101273141B (en) | 2005-07-26 | 2013-03-27 | 桑格摩生物科学股份有限公司 | Targeted integration and expression of exogenous nucleic acid sequences |
| WO2008063982A2 (en) * | 2006-11-13 | 2008-05-29 | Procell Corp | High mannose glycoprotein epitopes |
| US20100145032A1 (en) * | 2007-01-18 | 2010-06-10 | Suomen Punainen Risti, Veripalelu | Novel carbohydrate profile compositions from human cells and methods for analysis and modification thereof |
| WO2010033085A1 (en) | 2008-09-19 | 2010-03-25 | Agency For Science, Technology And Research (A*Star) | Chinese hamster ovary cell lines |
| US20110016546A1 (en) | 2008-12-04 | 2011-01-20 | Sigma-Aldrich Co. | Porcine genome editing with zinc finger nucleases |
| US20110030072A1 (en) * | 2008-12-04 | 2011-02-03 | Sigma-Aldrich Co. | Genome editing of immunodeficiency genes in animals |
| US20130164329A1 (en) | 2010-02-17 | 2013-06-27 | Alnylam Pharmaceuticals, Inc. | Cell-based methods and reagents |
| MX2013006234A (en) | 2011-01-06 | 2013-08-01 | Univ Johns Hopkins | Method of production of recombinant glycoproteins with increased circulatory half-life in mammalian cells. |
| BR112014016614B1 (en) | 2012-01-11 | 2022-02-01 | Sigma-Aldrich Co. Llc | METHODS FOR PRODUCING A CELL DEFICIENT IN MANOSIL (ALPHA-1,3-)-GLYCOPROTEIN BETA-1,2-NACETYL GLUCOSE-MINILTRANSFERASE I (MGAT1) AND PRODUCING A RECOMBINANT PROTEIN SHOWING ONE OR MORE TERMINAL MANNOSE RESIDUES |
-
2013
- 2013-01-10 BR BR112014016614-5A patent/BR112014016614B1/en active IP Right Grant
- 2013-01-10 EP EP13735783.6A patent/EP2802654B1/en active Active
- 2013-01-10 US US14/371,137 patent/US9376484B2/en active Active
- 2013-01-10 SG SG11201403814RA patent/SG11201403814RA/en unknown
- 2013-01-10 KR KR1020147017287A patent/KR102212865B1/en active IP Right Grant
- 2013-01-10 WO PCT/US2013/020947 patent/WO2013106515A1/en active Application Filing
- 2013-01-10 JP JP2014552284A patent/JP6262665B2/en active Active
- 2013-01-10 ES ES13735783T patent/ES2733248T3/en active Active
- 2013-01-10 CN CN201380005345.XA patent/CN104245932A/en active Pending
- 2013-01-10 CN CN201910526345.3A patent/CN110438083A/en active Pending
-
2016
- 2016-06-02 US US15/171,977 patent/US9670271B2/en active Active
-
2017
- 2017-08-09 JP JP2017154341A patent/JP2018023379A/en active Pending
-
2019
- 2019-12-20 JP JP2019230287A patent/JP2020072677A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015503360A (en) | 2015-02-02 |
| CN104245932A (en) | 2014-12-24 |
| US20140349341A1 (en) | 2014-11-27 |
| KR102212865B1 (en) | 2021-02-05 |
| US20160272696A1 (en) | 2016-09-22 |
| KR20140111657A (en) | 2014-09-19 |
| CN110438083A (en) | 2019-11-12 |
| EP2802654A1 (en) | 2014-11-19 |
| JP2018023379A (en) | 2018-02-15 |
| JP6262665B2 (en) | 2018-01-17 |
| ES2733248T3 (en) | 2019-11-28 |
| EP2802654A4 (en) | 2015-11-04 |
| BR112014016614B1 (en) | 2022-02-01 |
| EP2802654B1 (en) | 2019-04-03 |
| US9376484B2 (en) | 2016-06-28 |
| US9670271B2 (en) | 2017-06-06 |
| JP2020072677A (en) | 2020-05-14 |
| BR112014016614A2 (en) | 2020-10-27 |
| WO2013106515A1 (en) | 2013-07-18 |
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