SG11201402661TA - Therapeutic agents comprising insulin amino acid sequences - Google Patents

Therapeutic agents comprising insulin amino acid sequences

Info

Publication number
SG11201402661TA
SG11201402661TA SG11201402661TA SG11201402661TA SG11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA
Authority
SG
Singapore
Prior art keywords
amino acid
acid sequences
therapeutic agents
insulin amino
insulin
Prior art date
Application number
SG11201402661TA
Other languages
English (en)
Inventor
James Jowett
Christopher Woods
Original Assignee
Phasebio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phasebio Pharmaceuticals Inc filed Critical Phasebio Pharmaceuticals Inc
Publication of SG11201402661TA publication Critical patent/SG11201402661TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
SG11201402661TA 2011-11-28 2012-11-28 Therapeutic agents comprising insulin amino acid sequences SG11201402661TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161563985P 2011-11-28 2011-11-28
PCT/US2012/066795 WO2013082116A1 (en) 2011-11-28 2012-11-28 Therapeutic agents comprising insulin amino acid sequences

Publications (1)

Publication Number Publication Date
SG11201402661TA true SG11201402661TA (en) 2014-08-28

Family

ID=48536000

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201402661TA SG11201402661TA (en) 2011-11-28 2012-11-28 Therapeutic agents comprising insulin amino acid sequences

Country Status (14)

Country Link
US (2) US20130150291A1 (ko)
EP (1) EP2785367A4 (ko)
JP (1) JP2014534265A (ko)
KR (1) KR20140103985A (ko)
CN (1) CN104080473A (ko)
AU (1) AU2012346058A1 (ko)
BR (1) BR112014012789A2 (ko)
CA (1) CA2856967A1 (ko)
HK (1) HK1202067A1 (ko)
IL (1) IL232781A0 (ko)
MX (1) MX2014006391A (ko)
RU (1) RU2014126244A (ko)
SG (1) SG11201402661TA (ko)
WO (1) WO2013082116A1 (ko)

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US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
EP3412300A1 (en) 2008-06-27 2018-12-12 Duke University Therapeutic agents comprising elastin-like peptides
ES2669190T3 (es) 2011-06-06 2018-05-24 Phasebio Pharmaceuticals, Inc. Uso de péptidos intestinales vasoactivos modificados en el tratamiento de la hipertensión
US20150290328A1 (en) 2012-11-20 2015-10-15 Phasebio Pharmaceuticals, Inc. Formulations of active agents for sustained release
CN105025919A (zh) * 2013-01-15 2015-11-04 费斯生物制药公司 用于血糖控制的治疗剂、组合物和方法
AU2015255752B2 (en) 2014-05-08 2020-07-23 Immunoforge Co., Ltd. Methods and compositions for treating Cystic Fibrosis
CA2967394A1 (en) * 2014-11-21 2016-05-26 Phasebio Pharmaceuticals, Inc. Elp fusion proteins for controlled and sustained release
US10688156B2 (en) 2015-02-09 2020-06-23 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating muscle disease and disorders
TW201718627A (zh) * 2015-06-11 2017-06-01 梅茲製藥有限兩合公司 重組梭菌神經毒素及其使用與形成方法、包括其之醫藥組合物及對應其之前驅物、編碼前驅物之核酸序列及其獲得方法與前驅物之形成方法、載體與包括核酸序列之重組宿主細胞
EP3124495A1 (en) * 2015-07-31 2017-02-01 Centre National de la Recherche Scientifique (C.N.R.S.) Derivatives of elastin-like polypeptides and uses thereof
EA037478B1 (ru) 2015-08-04 2021-04-01 Дьюк Юниверсити Генетически кодируемые внутренне неупорядоченные полимеры-"невидимки" для доставки и способы их применения
CN105061566A (zh) * 2015-09-05 2015-11-18 苏州普罗达生物科技有限公司 拟胰岛素多肽及其应用
US20180291077A1 (en) * 2015-09-24 2018-10-11 Hanmi Pharm. Co., Ltd Method of insulin production
KR101815080B1 (ko) 2015-11-03 2018-01-04 재단법인대구경북과학기술원 췌장소도세포 및 엘라스틴 유사 인공 세포외 기질을 포함하는 당뇨병 치료용 약학적 조성물
US11752213B2 (en) 2015-12-21 2023-09-12 Duke University Surfaces having reduced non-specific binding and antigenicity
CN108463242A (zh) 2016-03-02 2018-08-28 梅尔兹制药公司 包含肉毒杆菌毒素的组合物
EP3448872A4 (en) 2016-04-27 2019-12-11 The Regents of the University of California PREPARATION OF FUNCTIONAL HOMOCYSTEINRESTES IN POLYPEPTIDES AND PEPTIDES
ES2909074T3 (es) * 2016-05-06 2022-05-05 Phasebio Pharmaceuticals Inc Proteínas de fusión ELP para liberación controlada y sostenida
WO2017210476A1 (en) 2016-06-01 2017-12-07 Duke University Nonfouling biosensors
JP2020500150A (ja) * 2016-09-23 2020-01-09 デューク ユニバーシティ 下限臨界溶液温度挙動を有する非反復かつ非構造的ポリペプチド
US11220467B2 (en) 2017-01-11 2022-01-11 Recycle Track Systems, Inc. Indoor food waste fermentation and recycling process
US11648200B2 (en) 2017-01-12 2023-05-16 Duke University Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly
US11554097B2 (en) 2017-05-15 2023-01-17 Duke University Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents
EP3642222A1 (en) 2017-06-20 2020-04-29 Merz Pharma GmbH & Co. KGaA Novel recombinant botulinum toxin with increased duration of effect
US11680083B2 (en) 2017-06-30 2023-06-20 Duke University Order and disorder as a design principle for stimuli-responsive biopolymer networks
EP3649143B1 (en) 2017-07-06 2022-08-31 Merz Pharma GmbH & Co. KGaA Novel recombinant botulinum neurotoxins with increased duration of effect
US11649275B2 (en) 2018-08-02 2023-05-16 Duke University Dual agonist fusion proteins
KR102456958B1 (ko) * 2019-05-14 2022-10-21 강원대학교 산학협력단 당뇨병성 합병증의 예방 또는 치료용 약제학적 조성물
CN111939244A (zh) * 2019-05-14 2020-11-17 阿莫生命科学有限公司 用于预防或治疗糖尿病并发症的药物组合物
US11512314B2 (en) 2019-07-12 2022-11-29 Duke University Amphiphilic polynucleotides
JPWO2021112249A1 (ko) * 2019-12-06 2021-06-10

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ES2230727T3 (es) * 1997-11-12 2005-05-01 Alza Corporation Procedimiento de administracion dermal de polipeptidos.
US7846445B2 (en) * 2005-09-27 2010-12-07 Amunix Operating, Inc. Methods for production of unstructured recombinant polymers and uses thereof
US8334257B2 (en) * 2005-12-20 2012-12-18 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
EP1987067A4 (en) * 2006-02-15 2012-01-25 Imclone Llc ANTIBODY FORMULATION
CN101616685B (zh) * 2006-03-06 2013-07-24 阿穆尼克斯运营公司 非结构化重组聚合物和其应用
EP3412300A1 (en) * 2008-06-27 2018-12-12 Duke University Therapeutic agents comprising elastin-like peptides
WO2010014689A1 (en) * 2008-07-29 2010-02-04 Phasebio Pharmaceuticals, Inc. Pharmaceutical formulations comprising elastin-like proteins
AU2010277560B2 (en) * 2009-07-31 2014-12-11 Sanofi-Aventis Deutschland Gmbh Long acting insulin composition
BR112012003327A2 (pt) * 2009-08-14 2017-06-06 Phasebio Pharmaceuticals Inc peptídeos intestinais vasoativos modificados

Also Published As

Publication number Publication date
US20130150291A1 (en) 2013-06-13
RU2014126244A (ru) 2016-01-27
MX2014006391A (es) 2014-09-22
WO2013082116A1 (en) 2013-06-06
KR20140103985A (ko) 2014-08-27
EP2785367A4 (en) 2015-06-17
CN104080473A (zh) 2014-10-01
IL232781A0 (en) 2014-07-31
CA2856967A1 (en) 2013-06-06
EP2785367A1 (en) 2014-10-08
AU2012346058A1 (en) 2014-06-12
JP2014534265A (ja) 2014-12-18
US20140364362A1 (en) 2014-12-11
BR112014012789A2 (pt) 2019-09-24
HK1202067A1 (en) 2015-09-18

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