SG10202112147UA - Compositions and methods for producing genetically modified animals - Google Patents

Compositions and methods for producing genetically modified animals

Info

Publication number
SG10202112147UA
SG10202112147UA SG10202112147UA SG10202112147UA SG10202112147UA SG 10202112147U A SG10202112147U A SG 10202112147UA SG 10202112147U A SG10202112147U A SG 10202112147UA SG 10202112147U A SG10202112147U A SG 10202112147UA SG 10202112147U A SG10202112147U A SG 10202112147UA
Authority
SG
Singapore
Prior art keywords
involves
c57bl
gene
cell
sequence
Prior art date
Application number
SG10202112147UA
Other languages
English (en)
Inventor
Koentgen Frank
Original Assignee
Ozgene Holdings Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2013904307A external-priority patent/AU2013904307A0/en
Application filed by Ozgene Holdings Pty Ltd filed Critical Ozgene Holdings Pty Ltd
Publication of SG10202112147UA publication Critical patent/SG10202112147UA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knock-out vertebrates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8775—Murine embryos
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/12—Animals modified by administration of exogenous cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated
    • A01K2267/025—Animal producing cells or organs for transplantation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
SG10202112147UA 2013-11-07 2014-11-07 Compositions and methods for producing genetically modified animals SG10202112147UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2013904307A AU2013904307A0 (en) 2013-11-07 Compositions and methods for producing genetically modified animals
AU2014902162A AU2014902162A0 (en) 2014-06-06 Compostion and methods for producing genetically modified animals

Publications (1)

Publication Number Publication Date
SG10202112147UA true SG10202112147UA (en) 2021-12-30

Family

ID=53040710

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202112147UA SG10202112147UA (en) 2013-11-07 2014-11-07 Compositions and methods for producing genetically modified animals
SG11201603352SA SG11201603352SA (en) 2013-11-07 2014-11-07 Compositions and methods for producing genetically modified animals

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201603352SA SG11201603352SA (en) 2013-11-07 2014-11-07 Compositions and methods for producing genetically modified animals

Country Status (15)

Country Link
US (2) US20160360736A1 (https=)
EP (2) EP3066204B1 (https=)
JP (2) JP6845013B2 (https=)
KR (3) KR102444117B1 (https=)
CN (1) CN105899667A (https=)
AU (2) AU2014346342C1 (https=)
CA (1) CA2928744C (https=)
DK (1) DK3066204T3 (https=)
ES (1) ES2886146T3 (https=)
HU (1) HUE055766T2 (https=)
IL (2) IL307495B2 (https=)
NZ (2) NZ719493A (https=)
PT (1) PT3066204T (https=)
SG (2) SG10202112147UA (https=)
WO (1) WO2015066768A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015066768A1 (en) 2013-11-07 2015-05-14 Ozgene Holdings Pty Ltd Compositions and methods for producing genetically modified animals
CN118652837A (zh) * 2018-01-12 2024-09-17 加利福利亚大学董事会 稳定的多能牛胚胎干细胞的高效衍生
GB201816633D0 (en) * 2018-10-12 2018-11-28 Univ Edinburgh Genetically modified avians and method for the reconstitution thereof
CN113136439B (zh) * 2021-05-28 2022-04-08 兰州大学 一种检测绵羊lipe基因单核苷酸多态性的方法及其应用
CN114592011B (zh) * 2022-05-10 2022-08-05 广东药康生物科技有限公司 一种ptdss2条件性基因敲除小鼠模型的构建方法

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JP3034320U (ja) * 1996-08-02 1997-02-18 幸夫 冨澤 蛇腹式カード
JP2001008577A (ja) 1999-06-30 2001-01-16 Mitsubishi Chemicals Corp 生殖毒性化学物質のモニタリングに使用されるトランスジェニックマウス
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
JP2004512020A (ja) 2000-06-23 2004-04-22 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 組換え構築物ならびにこれを遺伝子発現を減少させる際に用いる方法
SI1409244T1 (sl) 2001-07-19 2008-04-30 Lankhorst Pure Composites Bv Poliolefinski film, trak ali nit
KR100828506B1 (ko) 2002-02-14 2008-05-13 도꾸리쯔교세이호징 가가꾸 기쥬쯔 신꼬 기꼬 마우스 정자 형성 유전자와 인간 남성 불임 관련 유전자,및 이들을 사용한 진단 시스템
CA2477112A1 (en) * 2002-02-27 2003-09-04 Yasumitsu Nagao A method for producing germline chimeric animal
US20050125853A1 (en) * 2002-03-22 2005-06-09 St. Jude Children's Resarch Hospital Method for generating genetically modified animals
ES2463476T3 (es) 2004-10-19 2014-05-28 Regeneron Pharmaceuticals, Inc. Método para generar un ratón homocigótico para una modificación genética
US7891320B2 (en) 2006-12-27 2011-02-22 Kao Corporation Sheet for pets
ITRM20090235A1 (it) * 2009-05-12 2010-11-13 Uni Degli Studi Perugia Modello murino ottenuto mediante inattivazione del gene glucocorticoid-induced leucine zipper, metodo per la sua preparazione e relativi usi.
JP4949434B2 (ja) 2009-05-19 2012-06-06 株式会社マーク・コーポレーション ラベルシート
JP5935692B2 (ja) * 2010-08-31 2016-06-15 国立大学法人 熊本大学 マウス系統を樹立する方法
KR20130030355A (ko) * 2011-09-17 2013-03-27 유종현 배변패드
WO2012092284A1 (en) * 2010-12-27 2012-07-05 The Jackson Laboratory Compositions and methods relating to non-human animals modified to promote production of selected gametes
CN102540592B (zh) 2012-03-09 2014-06-25 深圳市华星光电技术有限公司 Pva像素电极及相应的液晶显示装置
KR20140106134A (ko) * 2013-02-26 2014-09-03 윤수경 배변패드 제조장치 및 이를 이용한 배변패드 제조방법
WO2015066768A1 (en) 2013-11-07 2015-05-14 Ozgene Holdings Pty Ltd Compositions and methods for producing genetically modified animals
KR20180005002A (ko) * 2016-07-05 2018-01-15 김윤수 애완견 배변패드
KR102311995B1 (ko) * 2018-04-08 2021-10-13 김종수 애완동물 배설물 자동처리장치
CN209403260U (zh) 2018-11-14 2019-09-20 绍兴兴科元管业有限公司 一种宠物尿垫组件

Also Published As

Publication number Publication date
DK3066204T3 (da) 2021-08-30
IL307495B2 (en) 2025-11-01
NZ719493A (en) 2020-02-28
WO2015066768A1 (en) 2015-05-14
SG11201603352SA (en) 2016-05-30
CA2928744C (en) 2022-12-06
JP2016539660A (ja) 2016-12-22
JP2020202857A (ja) 2020-12-24
KR102444117B1 (ko) 2022-09-16
KR20160084431A (ko) 2016-07-13
JP6845013B2 (ja) 2021-03-17
HUE055766T2 (hu) 2021-12-28
PT3066204T (pt) 2021-09-06
NZ758970A (en) 2022-10-28
AU2014346342B2 (en) 2020-02-20
ES2886146T3 (es) 2021-12-16
IL245306A0 (en) 2016-06-30
AU2020202321B2 (en) 2021-12-16
US11937586B2 (en) 2024-03-26
IL307495B1 (en) 2025-07-01
AU2020202321A1 (en) 2020-04-23
AU2014346342C1 (en) 2020-08-13
US20220201992A1 (en) 2022-06-30
CN105899667A (zh) 2016-08-24
EP4043575A1 (en) 2022-08-17
US20160360736A1 (en) 2016-12-15
EP3066204B1 (en) 2021-06-02
CA2928744A1 (en) 2015-05-14
IL307495A (en) 2023-12-01
EP3066204A4 (en) 2017-06-21
AU2014346342A1 (en) 2016-05-19
EP3066204A1 (en) 2016-09-14
KR20220142474A (ko) 2022-10-21
KR20240049835A (ko) 2024-04-17

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