SG10201914028TA - Methods for absolute quantification of low-abundance polypeptides using mass spectrometry - Google Patents

Methods for absolute quantification of low-abundance polypeptides using mass spectrometry

Info

Publication number
SG10201914028TA
SG10201914028TA SG10201914028TA SG10201914028TA SG10201914028TA SG 10201914028T A SG10201914028T A SG 10201914028TA SG 10201914028T A SG10201914028T A SG 10201914028TA SG 10201914028T A SG10201914028T A SG 10201914028TA SG 10201914028T A SG10201914028T A SG 10201914028TA
Authority
SG
Singapore
Prior art keywords
methods
low
mass spectrometry
absolute quantification
abundance polypeptides
Prior art date
Application number
SG10201914028TA
Other languages
English (en)
Inventor
Martha Stapels
Michelle Busch
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of SG10201914028TA publication Critical patent/SG10201914028TA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/7233Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/15Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
SG10201914028TA 2017-06-02 2018-06-01 Methods for absolute quantification of low-abundance polypeptides using mass spectrometry SG10201914028TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762514587P 2017-06-02 2017-06-02

Publications (1)

Publication Number Publication Date
SG10201914028TA true SG10201914028TA (en) 2020-03-30

Family

ID=62791815

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201914028TA SG10201914028TA (en) 2017-06-02 2018-06-01 Methods for absolute quantification of low-abundance polypeptides using mass spectrometry

Country Status (18)

Country Link
US (2) US10900972B2 (fr)
EP (2) EP4033250A1 (fr)
JP (2) JP7193479B2 (fr)
KR (2) KR102509880B1 (fr)
CN (2) CN117230137A (fr)
AU (1) AU2018275881B2 (fr)
BR (1) BR112019025095A2 (fr)
CA (1) CA3065321A1 (fr)
CY (1) CY1125303T1 (fr)
DK (1) DK3631469T3 (fr)
ES (1) ES2907024T3 (fr)
HU (1) HUE057483T2 (fr)
IL (1) IL270972B2 (fr)
MX (1) MX2024008098A (fr)
RU (1) RU2768497C2 (fr)
SG (1) SG10201914028TA (fr)
TW (1) TWI808975B (fr)
WO (1) WO2018223076A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7193479B2 (ja) 2017-06-02 2022-12-20 ジェンザイム・コーポレーション 質量分析を使用する低存在量のポリペプチドの絶対定量のための方法
US12012425B2 (en) 2021-08-26 2024-06-18 King Abdullah University Of Science And Technology Nickel nanoparticle functionalized fibrous hierarchical zeolite and method of making the same
US11851335B2 (en) 2021-08-26 2023-12-26 Saudi Arabian Oil Company Nickel-containing organometallic functionalized fibrous hierarchical zeolite and method of making the same
CN114705794B (zh) * 2022-04-15 2022-12-02 西湖大学 一种生物样本的蛋白质组学分析方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2487821A1 (fr) * 2001-05-30 2002-12-05 Andrew Emili Base de donnees pour profil d'expression de proteine
EP1647825A3 (fr) * 2001-12-08 2008-12-10 Micromass UK Limited Méthode de spectrométrie de masse
JP2005522713A (ja) 2002-04-15 2005-07-28 サーモ フィニガン エルエルシー 生物学的分子の定量
JP4563764B2 (ja) 2004-10-01 2010-10-13 丸善製薬株式会社 ペプチドの定量方法
JP4990273B2 (ja) 2005-06-03 2012-08-01 ウオーターズ・テクノロジーズ・コーポレイシヨン Lc/msを用いるタンパク質を絶対定量するためのシステムおよび方法
WO2006133192A2 (fr) 2005-06-03 2006-12-14 Waters Investments Limited Generation et utilisation d'un catalogue d'informations associees a des polypeptides pour des analyses chimiques
JP4913587B2 (ja) 2006-12-28 2012-04-11 雪印メグミルク株式会社 ペプチドおよびタンパク質定量法
EP2735871B1 (fr) * 2011-07-22 2017-12-06 Tohoku University Procédé de fabrication d'un fragment peptidique cible marqué avec des isotopes stables en spectrométrie de masse
CN103134860A (zh) * 2011-11-23 2013-06-05 上海市公共卫生临床中心 一种目标多肽和蛋白质定量测定方法
GB201213127D0 (en) * 2012-07-24 2012-09-05 Univ Dundee Novel isotopic labelling method
EP3004871B1 (fr) 2013-06-05 2019-05-15 DH Technologies Development PTE. Ltd. Techniques d'acquisition swathtm indépendantes des données pour la détection de contaminants protéiques issus des cellules hôtes dans des produits protéiques biothérapiques
WO2015049763A1 (fr) 2013-10-03 2015-04-09 株式会社島津製作所 Procédé de détermination quantitative de protéines par analyse de masses
JP7193479B2 (ja) 2017-06-02 2022-12-20 ジェンザイム・コーポレーション 質量分析を使用する低存在量のポリペプチドの絶対定量のための方法

Also Published As

Publication number Publication date
JP2023022282A (ja) 2023-02-14
DK3631469T3 (da) 2022-03-28
RU2019144039A (ru) 2021-07-12
WO2018223076A1 (fr) 2018-12-06
US10900972B2 (en) 2021-01-26
JP2020522692A (ja) 2020-07-30
EP4033250A1 (fr) 2022-07-27
CN110678756A (zh) 2020-01-10
MX2024008098A (es) 2024-07-15
TW201908731A (zh) 2019-03-01
CN117230137A (zh) 2023-12-15
IL270972A (en) 2020-01-30
US20190004059A1 (en) 2019-01-03
EP3631469B1 (fr) 2022-01-05
CN110678756B (zh) 2023-09-05
RU2768497C2 (ru) 2022-03-24
CA3065321A1 (fr) 2018-12-06
BR112019025095A2 (pt) 2020-06-23
JP7431933B2 (ja) 2024-02-15
KR20200013725A (ko) 2020-02-07
AU2018275881A1 (en) 2020-01-23
ES2907024T3 (es) 2022-04-21
KR102509880B1 (ko) 2023-03-13
AU2018275881B2 (en) 2024-08-01
TWI808975B (zh) 2023-07-21
EP3631469A1 (fr) 2020-04-08
CY1125303T1 (el) 2024-02-16
IL270972B2 (en) 2023-12-01
IL270972B1 (en) 2023-08-01
HUE057483T2 (hu) 2022-05-28
US20210102952A1 (en) 2021-04-08
KR20220163526A (ko) 2022-12-09
KR102509881B1 (ko) 2023-03-14
RU2019144039A3 (fr) 2021-08-19
JP7193479B2 (ja) 2022-12-20
US11835434B2 (en) 2023-12-05

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