HUE057483T2 - Eljárások kis gyakoriságú polipeptidek abszolút kvantifikálására tömeg-spektrometria alkalmazásával - Google Patents

Eljárások kis gyakoriságú polipeptidek abszolút kvantifikálására tömeg-spektrometria alkalmazásával

Info

Publication number
HUE057483T2
HUE057483T2 HUE18735751A HUE18735751A HUE057483T2 HU E057483 T2 HUE057483 T2 HU E057483T2 HU E18735751 A HUE18735751 A HU E18735751A HU E18735751 A HUE18735751 A HU E18735751A HU E057483 T2 HUE057483 T2 HU E057483T2
Authority
HU
Hungary
Prior art keywords
methods
low
mass spectrometry
absolute quantification
abundance polypeptides
Prior art date
Application number
HUE18735751A
Other languages
English (en)
Inventor
Martha Stapels
Michelle Busch
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of HUE057483T2 publication Critical patent/HUE057483T2/hu

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/7233Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/15Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
HUE18735751A 2017-06-02 2018-06-01 Eljárások kis gyakoriságú polipeptidek abszolút kvantifikálására tömeg-spektrometria alkalmazásával HUE057483T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762514587P 2017-06-02 2017-06-02

Publications (1)

Publication Number Publication Date
HUE057483T2 true HUE057483T2 (hu) 2022-05-28

Family

ID=62791815

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE18735751A HUE057483T2 (hu) 2017-06-02 2018-06-01 Eljárások kis gyakoriságú polipeptidek abszolút kvantifikálására tömeg-spektrometria alkalmazásával

Country Status (18)

Country Link
US (2) US10900972B2 (hu)
EP (2) EP3631469B1 (hu)
JP (2) JP7193479B2 (hu)
KR (2) KR102509881B1 (hu)
CN (2) CN117230137A (hu)
AU (1) AU2018275881B2 (hu)
BR (1) BR112019025095A2 (hu)
CA (1) CA3065321A1 (hu)
CY (1) CY1125303T1 (hu)
DK (1) DK3631469T3 (hu)
ES (1) ES2907024T3 (hu)
HU (1) HUE057483T2 (hu)
IL (1) IL270972B2 (hu)
MX (1) MX2024008098A (hu)
RU (1) RU2768497C2 (hu)
SG (1) SG10201914028TA (hu)
TW (1) TWI808975B (hu)
WO (1) WO2018223076A1 (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2907024T3 (es) 2017-06-02 2022-04-21 Genzyme Corp Métodos para la cuantificación absoluta de polipéptidos de baja abundancia usando espectrometría de masas
US12012425B2 (en) 2021-08-26 2024-06-18 King Abdullah University Of Science And Technology Nickel nanoparticle functionalized fibrous hierarchical zeolite and method of making the same
US11851335B2 (en) 2021-08-26 2023-12-26 Saudi Arabian Oil Company Nickel-containing organometallic functionalized fibrous hierarchical zeolite and method of making the same
CN114705794B (zh) * 2022-04-15 2022-12-02 西湖大学 一种生物样本的蛋白质组学分析方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2487821A1 (en) * 2001-05-30 2002-12-05 Andrew Emili Method to identify constituent proteins by peptides profiling
EP1469314B1 (en) * 2001-12-08 2008-08-06 Micromass UK Limited Method of mass spectometry
CN100489534C (zh) * 2002-04-15 2009-05-20 萨莫芬尼根有限责任公司 生物学分子的定量
JP4563764B2 (ja) * 2004-10-01 2010-10-13 丸善製薬株式会社 ペプチドの定量方法
JP4990273B2 (ja) 2005-06-03 2012-08-01 ウオーターズ・テクノロジーズ・コーポレイシヨン Lc/msを用いるタンパク質を絶対定量するためのシステムおよび方法
WO2006133192A2 (en) 2005-06-03 2006-12-14 Waters Investments Limited Generation and use of a catalog of polypeptide-related information for chemical analyses
JP4913587B2 (ja) 2006-12-28 2012-04-11 雪印メグミルク株式会社 ペプチドおよびタンパク質定量法
US9163276B2 (en) 2011-07-22 2015-10-20 Tohoku University Method for fabricating stable-isotope-labeled target peptide fragment in mass spectrometry
CN103134860A (zh) * 2011-11-23 2013-06-05 上海市公共卫生临床中心 一种目标多肽和蛋白质定量测定方法
GB201213127D0 (en) * 2012-07-24 2012-09-05 Univ Dundee Novel isotopic labelling method
WO2014195783A1 (en) 2013-06-05 2014-12-11 Dh Technologies Development Pte. Ltd. Swathtm data-independent acquisition technology for the detection of host cell protein contaminants in biotherapeutics protein products
WO2015049763A1 (ja) * 2013-10-03 2015-04-09 株式会社島津製作所 質量分析を用いたタンパク質の定量方法
ES2907024T3 (es) 2017-06-02 2022-04-21 Genzyme Corp Métodos para la cuantificación absoluta de polipéptidos de baja abundancia usando espectrometría de masas

Also Published As

Publication number Publication date
US20210102952A1 (en) 2021-04-08
MX2024008098A (es) 2024-07-15
IL270972A (en) 2020-01-30
RU2019144039A (ru) 2021-07-12
KR102509880B1 (ko) 2023-03-13
BR112019025095A2 (pt) 2020-06-23
KR102509881B1 (ko) 2023-03-14
TW201908731A (zh) 2019-03-01
TWI808975B (zh) 2023-07-21
EP4033250A1 (en) 2022-07-27
CA3065321A1 (en) 2018-12-06
JP2023022282A (ja) 2023-02-14
KR20200013725A (ko) 2020-02-07
DK3631469T3 (da) 2022-03-28
JP2020522692A (ja) 2020-07-30
RU2768497C2 (ru) 2022-03-24
SG10201914028TA (en) 2020-03-30
IL270972B1 (en) 2023-08-01
US10900972B2 (en) 2021-01-26
CY1125303T1 (el) 2024-02-16
US20190004059A1 (en) 2019-01-03
EP3631469B1 (en) 2022-01-05
WO2018223076A1 (en) 2018-12-06
CN117230137A (zh) 2023-12-15
JP7431933B2 (ja) 2024-02-15
AU2018275881B2 (en) 2024-08-01
CN110678756A (zh) 2020-01-10
IL270972B2 (en) 2023-12-01
AU2018275881A1 (en) 2020-01-23
KR20220163526A (ko) 2022-12-09
US11835434B2 (en) 2023-12-05
CN110678756B (zh) 2023-09-05
ES2907024T3 (es) 2022-04-21
JP7193479B2 (ja) 2022-12-20
RU2019144039A3 (hu) 2021-08-19
EP3631469A1 (en) 2020-04-08

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