SG10201903910RA - Differentiation-induced cell population from which undifferentiated cells have been removed, use of same, and method for producing same - Google Patents
Differentiation-induced cell population from which undifferentiated cells have been removed, use of same, and method for producing sameInfo
- Publication number
- SG10201903910RA SG10201903910RA SG10201903910RA SG10201903910RA SG10201903910RA SG 10201903910R A SG10201903910R A SG 10201903910RA SG 10201903910R A SG10201903910R A SG 10201903910RA SG 10201903910R A SG10201903910R A SG 10201903910RA SG 10201903910R A SG10201903910R A SG 10201903910RA
- Authority
- SG
- Singapore
- Prior art keywords
- same
- cell population
- differentiation
- induced cell
- undifferentiated cells
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0656—Adult fibroblasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/33—Fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/25—Tumour necrosing factors [TNF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014226682 | 2014-11-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201903910RA true SG10201903910RA (en) | 2019-05-30 |
Family
ID=55909242
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201703544QA SG11201703544QA (en) | 2014-11-07 | 2015-11-06 | Differentiation-induced cell population from which undifferentiated cells have been removed, use of same, and method for producing same |
SG10201903910RA SG10201903910RA (en) | 2014-11-07 | 2015-11-06 | Differentiation-induced cell population from which undifferentiated cells have been removed, use of same, and method for producing same |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201703544QA SG11201703544QA (en) | 2014-11-07 | 2015-11-06 | Differentiation-induced cell population from which undifferentiated cells have been removed, use of same, and method for producing same |
Country Status (9)
Country | Link |
---|---|
US (2) | US20170335284A1 (de) |
EP (2) | EP3216859B1 (de) |
JP (1) | JP6938154B2 (de) |
KR (1) | KR102639313B1 (de) |
CN (1) | CN107075473B (de) |
AU (1) | AU2015344125B2 (de) |
CA (1) | CA2966576C (de) |
SG (2) | SG11201703544QA (de) |
WO (1) | WO2016072519A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2018014972A (ja) * | 2016-07-29 | 2018-02-01 | 国立大学法人大阪大学 | 未分化細胞が除去された分化誘導細胞集団の製造方法 |
WO2018117127A1 (ja) * | 2016-12-20 | 2018-06-28 | 大日本住友製薬株式会社 | 未分化iPS細胞の除去剤 |
CN106854646A (zh) * | 2016-12-21 | 2017-06-16 | 南开大学 | 一种维持小鼠胚胎干细胞Naive状态的低表达Lin28的小鼠胚胎干细胞 |
CN110506109B (zh) * | 2017-06-05 | 2024-03-12 | 泰尔茂株式会社 | 细胞培养物的制造方法 |
WO2020067436A1 (ja) * | 2018-09-27 | 2020-04-02 | 国立大学法人大阪大学 | 多能性幹細胞由来細胞の移植片形成方法 |
JPWO2020067435A1 (ja) * | 2018-09-27 | 2021-09-09 | 国立大学法人大阪大学 | 多能性幹細胞由来細胞のシート化方法 |
JPWO2020067438A1 (ja) * | 2018-09-27 | 2021-08-30 | 国立大学法人大阪大学 | 多能性幹細胞由来細胞のシート化方法 |
CA3119746A1 (en) * | 2018-11-13 | 2020-05-22 | Memorial Sloan-Kettering Cancer Center | Stem cell-based multiplex methods and compositions |
JP7437328B2 (ja) | 2019-02-13 | 2024-02-22 | 住友ファーマ株式会社 | 多能性幹細胞の除去剤 |
KR102181316B1 (ko) * | 2019-05-31 | 2020-11-20 | 한국한의학연구원 | 봉독을 유효성분으로 포함하는 미분화 인간 유도만능 줄기세포의 선택적 세포사멸 유도용 조성물 및 이를 이용한 세포사멸 방법 |
CN111979175A (zh) * | 2020-08-28 | 2020-11-24 | 安徽惠恩生物科技股份有限公司 | 一种清除干细胞分化体系中残留的多能干细胞的方法 |
CN115074307B (zh) * | 2021-03-15 | 2024-01-09 | 广州暨南大学医药生物技术研究开发中心有限公司 | 小分子化合物诱导成纤维细胞重编程为睾丸支持细胞的方法及其应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050054103A1 (en) * | 2003-03-07 | 2005-03-10 | Tony Peled | Expansion of renewable stem cell populations using modulators of PI 3-kinase |
KR101348325B1 (ko) * | 2006-01-31 | 2014-01-08 | 각고호우징 게이오기주크 | 줄기세포 및 태아에서 유래된 심근세포 및 예정 심근세포의제조방법 |
SG170065A1 (en) * | 2006-03-06 | 2011-04-29 | Agency Science Tech & Res | Human embryonic stem cell methods and podxl expression |
KR100937456B1 (ko) * | 2007-08-01 | 2010-01-19 | 한국생명공학연구원 | 인간배아줄기세포를 조골세포 직계열로 분화시키는 방법 |
US20100035327A1 (en) * | 2008-08-11 | 2010-02-11 | Ann Marie Steele | Use of rice-derived products in a universal cell culture medium |
SG160248A1 (en) * | 2008-09-18 | 2010-04-29 | Agency Science Tech & Res | Use of novel monoclonal antibodies targeting human embryonic stem cells to characterize and kill induced pluripotent stem cells |
EP4364797A3 (de) * | 2009-10-19 | 2024-07-10 | FUJIFILM Cellular Dynamics, Inc. | Herstellung von kardiomyozyten |
HUE031073T2 (en) * | 2010-05-14 | 2017-06-28 | Dana Farber Cancer Inst Inc | Thieno triazolo-diazepine compounds for the treatment of neoplasia |
WO2011143651A1 (en) * | 2010-05-14 | 2011-11-17 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for modulating metabolism |
EP2582792B1 (de) * | 2010-06-18 | 2018-10-31 | FUJIFILM Cellular Dynamics, Inc. | Kardiomyozytenmedium mit dialysiertem serum |
US20130219954A1 (en) * | 2010-11-02 | 2013-08-29 | Nec Corporation | Cooling device and method for producing the same |
BR112013030166A2 (pt) * | 2011-06-09 | 2017-03-21 | Hoffmann La Roche | método de diferenciação de células haste pluripotentes em células leito vasculares, células endoteliais ou células dos músculos moles vasculares, banco biológico e uso de células endoteliais ou células dos músculos moles vasculares, composição terapêutica, métodos e usos. |
BR112014020697B1 (pt) * | 2012-02-24 | 2024-01-09 | Alteogen Inc | Anticorpo modificado compreendendo um motivo contendo cisteína na terminação do anticorpo, conjugado anticorpo-droga modificado compreendendo uma droga ligada ao anticorpo modificado e método de produção do mesmo |
US9657273B2 (en) * | 2012-10-12 | 2017-05-23 | Industry-University Cooperation Foundation Sogang University | Method for suppressing teratoma formation via selective cell death induction in undifferentiated human-induced pluripotent stem cells |
CA3177929A1 (en) * | 2012-12-21 | 2014-06-26 | Astellas Institute For Regenerative Medicine | Methods for production of platelets from pluripotent stem cells and compositions thereof |
-
2015
- 2015-11-06 SG SG11201703544QA patent/SG11201703544QA/en unknown
- 2015-11-06 EP EP15856872.5A patent/EP3216859B1/de active Active
- 2015-11-06 KR KR1020177014373A patent/KR102639313B1/ko active IP Right Grant
- 2015-11-06 CN CN201580058577.0A patent/CN107075473B/zh active Active
- 2015-11-06 AU AU2015344125A patent/AU2015344125B2/en active Active
- 2015-11-06 JP JP2016557838A patent/JP6938154B2/ja active Active
- 2015-11-06 SG SG10201903910RA patent/SG10201903910RA/en unknown
- 2015-11-06 WO PCT/JP2015/081408 patent/WO2016072519A1/ja active Application Filing
- 2015-11-06 US US15/523,746 patent/US20170335284A1/en not_active Abandoned
- 2015-11-06 CA CA2966576A patent/CA2966576C/en active Active
- 2015-11-06 EP EP19181427.6A patent/EP3567100A1/de not_active Ceased
-
2021
- 2021-07-28 US US17/386,776 patent/US20210388320A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2966576C (en) | 2021-07-20 |
CA2966576A1 (en) | 2016-05-12 |
EP3216859A4 (de) | 2017-09-13 |
JPWO2016072519A1 (ja) | 2017-08-17 |
AU2015344125A1 (en) | 2017-05-25 |
US20170335284A1 (en) | 2017-11-23 |
EP3567100A1 (de) | 2019-11-13 |
CN107075473A (zh) | 2017-08-18 |
US20210388320A1 (en) | 2021-12-16 |
EP3216859B1 (de) | 2020-03-11 |
CN107075473B (zh) | 2021-07-13 |
KR102639313B1 (ko) | 2024-02-20 |
SG11201703544QA (en) | 2017-06-29 |
JP6938154B2 (ja) | 2021-09-22 |
WO2016072519A1 (ja) | 2016-05-12 |
AU2015344125B2 (en) | 2022-03-24 |
EP3216859A1 (de) | 2017-09-13 |
KR20170074996A (ko) | 2017-06-30 |
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