SG10201703540WA - Surface modification of porous base supports - Google Patents

Surface modification of porous base supports

Info

Publication number
SG10201703540WA
SG10201703540WA SG10201703540WA SG10201703540WA SG10201703540WA SG 10201703540W A SG10201703540W A SG 10201703540WA SG 10201703540W A SG10201703540W A SG 10201703540WA SG 10201703540W A SG10201703540W A SG 10201703540WA SG 10201703540W A SG10201703540W A SG 10201703540WA
Authority
SG
Singapore
Prior art keywords
surface modification
porous base
base supports
supports
porous
Prior art date
Application number
SG10201703540WA
Other languages
English (en)
Inventor
Santosh Rahane
Nanying Bian
Daniel Scheid
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SG10201703540WA publication Critical patent/SG10201703540WA/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/283—Porous sorbents based on silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/289—Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/3085—Chemical treatments not covered by groups B01J20/3007 - B01J20/3078
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3225—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating involving a post-treatment of the coated or impregnated product
    • B01J20/3227—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating involving a post-treatment of the coated or impregnated product by end-capping, i.e. with or after the introduction of functional or ligand groups
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3234—Inorganic material layers
    • B01J20/3236—Inorganic material layers containing metal, other than zeolites, e.g. oxides, hydroxides, sulphides or salts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3278—Polymers being grafted on the carrier
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F292/00—Macromolecular compounds obtained by polymerising monomers on to inorganic materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
SG10201703540WA 2012-11-01 2013-10-02 Surface modification of porous base supports SG10201703540WA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261721178P 2012-11-01 2012-11-01

Publications (1)

Publication Number Publication Date
SG10201703540WA true SG10201703540WA (en) 2017-06-29

Family

ID=49304882

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201703540WA SG10201703540WA (en) 2012-11-01 2013-10-02 Surface modification of porous base supports
SG11201503216SA SG11201503216SA (en) 2012-11-01 2013-10-02 Surface modification of porous base supports

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201503216SA SG11201503216SA (en) 2012-11-01 2013-10-02 Surface modification of porous base supports

Country Status (9)

Country Link
US (1) US10166527B2 (zh)
EP (1) EP2914377A1 (zh)
JP (1) JP6336996B2 (zh)
KR (1) KR102132157B1 (zh)
CN (1) CN104736236B (zh)
CA (1) CA2889914C (zh)
SG (2) SG10201703540WA (zh)
TW (1) TWI609717B (zh)
WO (1) WO2014067605A1 (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015035076A1 (en) * 2013-09-04 2015-03-12 Sten Ohlson Weak affinity chromatography
DE102014016412A1 (de) * 2014-11-07 2016-05-12 Instraction Gmbh Chromatographisches Sorbens mit lipophilem aliphatischen Rest und anionischem oder deprotonierbarem Rest
DE102015011884A1 (de) 2015-09-10 2017-03-16 Sartorius Stedim Biotech Gmbh Adsorptionsmedium, Verfahren zu dessen Herstellung, sowie Verwendung desselben zur Aufreinigung von Biomolekülen
CN114749162A (zh) * 2016-07-14 2022-07-15 纯化迪发有限公司 包含聚合物纳米纤维的官能化色谱介质及其制备方法
CN106267897A (zh) * 2016-09-26 2017-01-04 延边大学 快速分离人参中人参皂苷和残留农药的方法
CN107413302B (zh) * 2017-09-04 2021-03-09 重庆希尔康血液净化器材研发有限公司 一种多点固定蛋白a的免疫吸附材料及其制备方法
JP7196203B2 (ja) * 2018-03-05 2022-12-26 キラル テクノロジーズ ヨーロッパ エスアーエス バイオセパレーションのための複合材料
US11045773B2 (en) * 2018-08-31 2021-06-29 Pall Corporation Salt tolerant porous medium
WO2020118371A1 (en) * 2018-12-12 2020-06-18 Newsouth Innovations Pty Limited Resin for desalination and process of regeneration
JP7156146B2 (ja) * 2019-04-10 2022-10-19 株式会社島津製作所 親水性材料の疎水化方法
CN114054006A (zh) * 2021-11-17 2022-02-18 苏州纳微科技股份有限公司 一种Oligo-dT亲和层析填料
CN114130377A (zh) * 2021-12-14 2022-03-04 无锡创谱生物科技有限公司 一种亲和层析填料、其制备方法及用途
CN114907606B (zh) * 2022-06-21 2023-11-17 华东理工大学 一种用于活性固载蛋白的聚合物刷表面改性方法
CN115850792B (zh) * 2022-09-30 2024-01-30 北京石油化工学院 一种高载量阴离子交换层析介质的制备方法
CN115445456B (zh) * 2022-09-30 2024-03-19 沃顿科技股份有限公司 一种高通量反渗透复合膜的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029583A (en) * 1975-02-28 1977-06-14 Purdue Research Foundation Chromatographic supports and methods and apparatus for preparing the same
US4108603A (en) * 1977-05-18 1978-08-22 Purdue Research Foundation Method for rapid analysis of hemoglobin variants by high speed liquid chromatography
JPS5849646A (ja) * 1981-09-17 1983-03-23 Fuji Photo Film Co Ltd 多孔質ガラスの耐アルカリ強化方法
EP0153937A4 (en) * 1983-08-17 1986-11-06 Macedo Pedro Manuel Buarque De IMPROVED SILICA BASED CHROMATOGRAPHIC MEDIA CONTAINING ADDITIVES.
US4724207A (en) 1984-02-02 1988-02-09 Cuno Incorporated Modified siliceous chromatographic supports
DE3811042A1 (de) * 1988-03-31 1989-10-19 Merck Patent Gmbh Ionenaustauscher
DE4310964A1 (de) * 1992-04-16 1993-10-21 Merck Patent Gmbh Aktivierte Trägermaterialien, ihre Herstellung und Verwendung
WO1996031549A1 (de) * 1995-04-07 1996-10-10 Mueller Egbert Dendrimere pfropfpolymerisate
US6689715B1 (en) * 2000-02-09 2004-02-10 Hammen Corporation Tethered polymer ligands
JP2010133734A (ja) * 2008-12-02 2010-06-17 Tosoh Corp アフィニティークロマトグラフィー用カルボキシル化担体、及びそれを用いたアフィニティークロマトグラフィー用分離剤
CN102335594B (zh) * 2011-06-16 2013-03-20 中国科学院长春应用化学研究所 一种带谷胱甘肽配体的亲和层析多孔介质的制备方法和应用

Also Published As

Publication number Publication date
JP6336996B2 (ja) 2018-06-06
US10166527B2 (en) 2019-01-01
EP2914377A1 (en) 2015-09-09
SG11201503216SA (en) 2015-05-28
TW201431604A (zh) 2014-08-16
CN104736236B (zh) 2017-06-13
KR102132157B1 (ko) 2020-07-09
WO2014067605A1 (en) 2014-05-08
CA2889914A1 (en) 2014-05-08
US20150298097A1 (en) 2015-10-22
KR20150082436A (ko) 2015-07-15
JP2016502457A (ja) 2016-01-28
TWI609717B (zh) 2018-01-01
CA2889914C (en) 2021-09-14
CN104736236A (zh) 2015-06-24

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