SE9503028D0 - Method of analysing chemical and physical interactions at a sensor surface - Google Patents

Method of analysing chemical and physical interactions at a sensor surface

Info

Publication number
SE9503028D0
SE9503028D0 SE9503028A SE9503028A SE9503028D0 SE 9503028 D0 SE9503028 D0 SE 9503028D0 SE 9503028 A SE9503028 A SE 9503028A SE 9503028 A SE9503028 A SE 9503028A SE 9503028 D0 SE9503028 D0 SE 9503028D0
Authority
SE
Sweden
Prior art keywords
film layer
intensity signal
interaction
light intensity
pct
Prior art date
Application number
SE9503028A
Other languages
English (en)
Swedish (sv)
Inventor
Bengt Ivarsson
Esa Stenberg
Original Assignee
Pharmacia Biosensor Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Biosensor Ab filed Critical Pharmacia Biosensor Ab
Priority to SE9503028A priority Critical patent/SE9503028D0/xx
Publication of SE9503028D0 publication Critical patent/SE9503028D0/xx
Priority to EP96929635A priority patent/EP0852010B1/en
Priority to DE69622176T priority patent/DE69622176T2/de
Priority to US09/043,006 priority patent/US6127183A/en
Priority to JP51112397A priority patent/JP3490458B2/ja
Priority to PCT/SE1996/001074 priority patent/WO1997009618A1/en
Priority to AT96929635T priority patent/ATE220208T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/05Flow-through cuvettes

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
SE9503028A 1995-09-01 1995-09-01 Method of analysing chemical and physical interactions at a sensor surface SE9503028D0 (sv)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE9503028A SE9503028D0 (sv) 1995-09-01 1995-09-01 Method of analysing chemical and physical interactions at a sensor surface
EP96929635A EP0852010B1 (en) 1995-09-01 1996-08-30 Monitoring of refractive index of optical sensor for determination of surface structure changes
DE69622176T DE69622176T2 (de) 1995-09-01 1996-08-30 Überwachung des refraktionsindex von optischen sensoren zur bestimmung von änderungen in der oberflächenstruktur
US09/043,006 US6127183A (en) 1995-09-01 1996-08-30 Monitoring of refractive index of optical sensor for determination of surface structure changes
JP51112397A JP3490458B2 (ja) 1995-09-01 1996-08-30 表面構造変化の決定のための光センサの屈折率の監視
PCT/SE1996/001074 WO1997009618A1 (en) 1995-09-01 1996-08-30 Monitoring of refractive index of optical sensor for determination of surface structure changes
AT96929635T ATE220208T1 (de) 1995-09-01 1996-08-30 Überwachung des refraktionsindex von optischen sensoren zur bestimmung von änderungen in der oberflächenstruktur

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9503028A SE9503028D0 (sv) 1995-09-01 1995-09-01 Method of analysing chemical and physical interactions at a sensor surface

Publications (1)

Publication Number Publication Date
SE9503028D0 true SE9503028D0 (sv) 1995-09-01

Family

ID=20399349

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9503028A SE9503028D0 (sv) 1995-09-01 1995-09-01 Method of analysing chemical and physical interactions at a sensor surface

Country Status (7)

Country Link
US (1) US6127183A (xx)
EP (1) EP0852010B1 (xx)
JP (1) JP3490458B2 (xx)
AT (1) ATE220208T1 (xx)
DE (1) DE69622176T2 (xx)
SE (1) SE9503028D0 (xx)
WO (1) WO1997009618A1 (xx)

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US6934024B2 (en) * 2000-10-18 2005-08-23 Regents Of The University Of Minnesota Ellipsometry methods and apparatus using solid immersion tunneling
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US7611908B2 (en) 2005-05-02 2009-11-03 Bioscale, Inc. Method and apparatus for therapeutic drug monitoring using an acoustic device
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US7867783B2 (en) * 2007-02-22 2011-01-11 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
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US20090041633A1 (en) * 2007-05-14 2009-02-12 Dultz Shane C Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7799558B1 (en) 2007-05-22 2010-09-21 Dultz Shane C Ligand binding assays on microarrays in closed multiwell plates
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CN101836102B (zh) * 2007-10-25 2012-02-29 皇家飞利浦电子股份有限公司 用于样品中靶粒子的传感器装置
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US9888839B2 (en) 2009-04-01 2018-02-13 Tearscience, Inc. Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on dry eye tear film characteristic analysis and dry eye symptoms
JP5658228B2 (ja) 2009-04-01 2015-01-21 テイアサイエンス・インコーポレーテツド 眼球涙液膜の画像形成、処理および/または表示を行いおよび/または眼球涙液膜層の厚さを測定する、眼球表面の干渉分光(osi)装置、システムおよび方法
US8915592B2 (en) 2009-04-01 2014-12-23 Tearscience, Inc. Apparatuses and methods of ocular surface interferometry (OSI) employing polarization and subtraction for imaging, processing, and/or displaying an ocular tear film
US8888286B2 (en) 2009-04-01 2014-11-18 Tearscience, Inc. Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography
US8163561B2 (en) 2009-11-30 2012-04-24 Corning Incorporated Method for depth resolved sensing of biological entities based on surface plasmon resonance sensors
US8243276B2 (en) 2009-11-30 2012-08-14 Corning Incorporated Variable penetration depth biosensor
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WO2011093782A1 (en) 2010-01-29 2011-08-04 Ge Healthcare Bio-Sciences Ab Method for determination of aggregates
CN103597335B (zh) * 2011-07-13 2015-12-09 英派尔科技开发有限公司 利用具有可刷新表面的表面等离子体监测分析物的方法和系统
US9885682B2 (en) * 2011-12-02 2018-02-06 The Johns Hopkins University Biosensor systems and related methods for detecting analytes in aqueous and biological environments
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SE462408B (sv) * 1988-11-10 1990-06-18 Pharmacia Ab Optiskt biosensorsystem utnyttjande ytplasmonresonans foer detektering av en specific biomolekyl, saett att kalibrera sensoranordningen samt saett att korrigera foer baslinjedrift i systemet
US5359681A (en) * 1993-01-11 1994-10-25 University Of Washington Fiber optic sensor and methods and apparatus relating thereto

Also Published As

Publication number Publication date
DE69622176T2 (de) 2002-12-12
US6127183A (en) 2000-10-03
EP0852010A1 (en) 1998-07-08
JPH11512186A (ja) 1999-10-19
JP3490458B2 (ja) 2004-01-26
DE69622176D1 (de) 2002-08-08
WO1997009618A1 (en) 1997-03-13
ATE220208T1 (de) 2002-07-15
EP0852010B1 (en) 2002-07-03

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