SE9501682D0 - Hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits - Google Patents

Hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits

Info

Publication number
SE9501682D0
SE9501682D0 SE9501682A SE9501682A SE9501682D0 SE 9501682 D0 SE9501682 D0 SE 9501682D0 SE 9501682 A SE9501682 A SE 9501682A SE 9501682 A SE9501682 A SE 9501682A SE 9501682 D0 SE9501682 D0 SE 9501682D0
Authority
SE
Sweden
Prior art keywords
amino
pct
ltb
disclosed
acid sequence
Prior art date
Application number
SE9501682A
Other languages
English (en)
Swedish (sv)
Inventor
Jan Holmgren
Michael R Lebens
Original Assignee
Jan Holmgren
Michael R Lebens
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jan Holmgren, Michael R Lebens filed Critical Jan Holmgren
Priority to SE9501682A priority Critical patent/SE9501682D0/xx
Publication of SE9501682D0 publication Critical patent/SE9501682D0/xx
Priority to AT96915275T priority patent/ATE284416T1/de
Priority to DE69634003T priority patent/DE69634003T2/de
Priority to CA2219943A priority patent/CA2219943C/en
Priority to DK96915275T priority patent/DK0824548T3/da
Priority to KR1019970707816A priority patent/KR100492305B1/ko
Priority to ES96915275T priority patent/ES2233968T3/es
Priority to EP96915275A priority patent/EP0824548B1/en
Priority to JP53323796A priority patent/JP4081140B2/ja
Priority to US08/952,337 priority patent/US6019973A/en
Priority to PCT/SE1996/000570 priority patent/WO1996034893A1/en
Priority to CNB961952237A priority patent/CN1154660C/zh
Priority to PT96915275T priority patent/PT824548E/pt
Priority to AU57085/96A priority patent/AU702637B2/en
Priority to IL118136A priority patent/IL118136A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SE9501682A 1995-05-05 1995-05-05 Hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits SE9501682D0 (sv)

Priority Applications (15)

Application Number Priority Date Filing Date Title
SE9501682A SE9501682D0 (sv) 1995-05-05 1995-05-05 Hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits
AU57085/96A AU702637B2 (en) 1995-05-05 1996-05-02 Hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits
ES96915275T ES2233968T3 (es) 1995-05-05 1996-05-02 Moleculas hibridas entre enterotoxina termolabil y subunidades b de toxina colerica.
JP53323796A JP4081140B2 (ja) 1995-05-05 1996-05-02 非耐熱性エンテロトキシンとコレラトキシンｂサブユニットの雑種分子
CA2219943A CA2219943C (en) 1995-05-05 1996-05-02 Hybrid molecules between heat-labile enterotoxin and cholera toxin b subunits
DK96915275T DK0824548T3 (da) 1995-05-05 1996-05-02 Hybridmolekyler mellem varmelabil enterotoksin og choleratoksin B-underenheder
KR1019970707816A KR100492305B1 (ko) 1995-05-05 1996-05-02 열에 불안정한 엔테로톡신과 콜레라톡신 b 유니트간의 혼성분자 및 구조유전자, 플라즈미드, 면역원성단백질, 백신, 약학적 조성물
AT96915275T ATE284416T1 (de) 1995-05-05 1996-05-02 Hybrid-moleküle aus hitzelabilem enterotoxin und choleratoxin-b-untereinheiten
EP96915275A EP0824548B1 (en) 1995-05-05 1996-05-02 Hybrid molecules between heat-labile enterotoxin and cholera toxin b subunits
DE69634003T DE69634003T2 (de) 1995-05-05 1996-05-02 Hybrid-moleküle aus hitzelabilem enterotoxin und choleratoxin-b-untereinheiten
US08/952,337 US6019973A (en) 1995-05-05 1996-05-02 Hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits
PCT/SE1996/000570 WO1996034893A1 (en) 1995-05-05 1996-05-02 Hybrid molecules between heat-labile enterotoxin and cholera toxin b subunits
CNB961952237A CN1154660C (zh) 1995-05-05 1996-05-02 热易变肠毒素和霍乱毒素b亚基之间的杂合分子
PT96915275T PT824548E (pt) 1995-05-05 1996-05-02 Moleculas hibridas entre a enterotoxina labil ao calor e a subunidade b da toxina da colera
IL118136A IL118136A (en) 1995-05-05 1996-05-03 Hybrid molecules between the heat-sensitive entrotoxin B subunits and cholera toxin B

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9501682A SE9501682D0 (sv) 1995-05-05 1995-05-05 Hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits

Publications (1)

Publication Number Publication Date
SE9501682D0 true SE9501682D0 (sv) 1995-05-05

Family

ID=20398217

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9501682A SE9501682D0 (sv) 1995-05-05 1995-05-05 Hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits

Country Status (15)

Country Link
US (1) US6019973A (ja)
EP (1) EP0824548B1 (ja)
JP (1) JP4081140B2 (ja)
KR (1) KR100492305B1 (ja)
CN (1) CN1154660C (ja)
AT (1) ATE284416T1 (ja)
AU (1) AU702637B2 (ja)
CA (1) CA2219943C (ja)
DE (1) DE69634003T2 (ja)
DK (1) DK0824548T3 (ja)
ES (1) ES2233968T3 (ja)
IL (1) IL118136A (ja)
PT (1) PT824548E (ja)
SE (1) SE9501682D0 (ja)
WO (1) WO1996034893A1 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE315048T1 (de) * 1995-10-31 2006-02-15 Maruha Corp Monoklonaler antikoerper spezifisch fuer prostaglandin d synthetase
US7914791B1 (en) 1998-05-08 2011-03-29 Trident Pharmaceuticals, Inc. Vaccine
AUPQ242899A0 (en) * 1999-08-25 1999-09-16 Aristocrat Leisure Industries Pty Ltd Gaming machine with buy feature games
US7041296B1 (en) * 1999-11-12 2006-05-09 The United States Of America As Represented By The Department Of Health And Human Services Methods of treating inflammatory bowel disease using cholera toxin B subunit
AU2001271268A1 (en) 2000-05-19 2001-12-03 The Administrators Of The Tulane Educational Fund Hybrid lt-a/ct-b holotoxin for use as an adjuvant
JP4599354B2 (ja) * 2003-07-21 2010-12-15 インターベツト・インターナシヨナル・ベー・ベー 大腸菌熱不安定性エンテロトキシンサブユニットに融合した志賀毒素サブユニットまたは志賀毒素様毒素サブユニットを含むハイブリッド毒素およびそのワクチン
WO2006011151A2 (en) * 2004-07-28 2006-02-02 Gavish - Galilee Bio Applications Ltd. Vaccine comprising recombinant ct or lt toxin
CA2846354C (en) * 2011-09-12 2023-04-25 Scandinavian Biopharma Holding Ab Vaccine for protection against etec-induced diarrhea comprising dmlt
KR20180083904A (ko) 2015-11-30 2018-07-23 이데미쓰 고산 가부시키가이샤 면역원성이 증강된 백신 항원
CN113813398B (zh) * 2021-04-23 2023-11-07 天津医科大学 一种向表面富含神经节苷脂的细胞递送重组蛋白质的方法
CN114409804B (zh) * 2022-01-07 2022-10-21 湖北神地生物科技有限公司 一种大肠杆菌肠毒素多表位融合蛋白及其制备方法和应用
CN114456240B (zh) * 2022-03-04 2023-08-15 青岛农业大学 一种非洲猪瘟病毒基因工程亚单位口服疫苗

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758655A (en) * 1983-01-03 1988-07-19 Scripps Clinic And Research Foundation Synthetic polypeptide corresponding to a portion of the heat-labile enterotoxin of escherichia coli, compositions and methods of therewith

Also Published As

Publication number Publication date
DE69634003T2 (de) 2005-12-29
CN1154660C (zh) 2004-06-23
KR19990008290A (ko) 1999-01-25
WO1996034893A1 (en) 1996-11-07
IL118136A0 (en) 1996-09-12
AU702637B2 (en) 1999-02-25
EP0824548A1 (en) 1998-02-25
IL118136A (en) 2006-04-10
ES2233968T3 (es) 2005-06-16
CA2219943C (en) 2010-10-12
EP0824548B1 (en) 2004-12-08
ATE284416T1 (de) 2004-12-15
PT824548E (pt) 2005-04-29
DK0824548T3 (da) 2005-04-11
KR100492305B1 (ko) 2006-01-12
AU5708596A (en) 1996-11-21
DE69634003D1 (de) 2005-01-13
US6019973A (en) 2000-02-01
JP4081140B2 (ja) 2008-04-23
JPH11504811A (ja) 1999-05-11
CA2219943A1 (en) 1996-11-07
CN1189840A (zh) 1998-08-05

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