SE9500724D0 - Filtrering - Google Patents

Filtrering

Info

Publication number
SE9500724D0
SE9500724D0 SE9500724A SE9500724A SE9500724D0 SE 9500724 D0 SE9500724 D0 SE 9500724D0 SE 9500724 A SE9500724 A SE 9500724A SE 9500724 A SE9500724 A SE 9500724A SE 9500724 D0 SE9500724 D0 SE 9500724D0
Authority
SE
Sweden
Prior art keywords
filtering
sodium
virus
potassium
filtration
Prior art date
Application number
SE9500724A
Other languages
English (en)
Swedish (sv)
Inventor
Stefan Winge
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26662085&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE9500724(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from SE9402254A external-priority patent/SE502820C2/sv
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Priority to SE9500724A priority Critical patent/SE9500724D0/xx
Publication of SE9500724D0 publication Critical patent/SE9500724D0/xx
Priority to ES95923651T priority patent/ES2105992T3/es
Priority to PT95923651T priority patent/PT796269E/pt
Priority to PCT/SE1995/000777 priority patent/WO1996000237A1/en
Priority to NZ288789A priority patent/NZ288789A/en
Priority to MX9606639A priority patent/MX9606639A/es
Priority to CA002192683A priority patent/CA2192683C/en
Priority to JP50306296A priority patent/JP3676370B2/ja
Priority to US08/750,664 priority patent/US6486306B1/en
Priority to DK95923651T priority patent/DK0796269T3/da
Priority to DE0796269T priority patent/DE796269T1/de
Priority to AU28132/95A priority patent/AU682274C/en
Priority to AT95923651T priority patent/ATE212354T1/de
Priority to EP95923651A priority patent/EP0796269B1/de
Priority to DE69525176T priority patent/DE69525176T2/de
Priority to NO19965523A priority patent/NO320952B1/no
Priority to FI965145A priority patent/FI965145A0/fi
Priority to GR970300038T priority patent/GR970300038T1/el
Priority to US09/511,953 priority patent/US6399357B1/en
Priority to US10/304,902 priority patent/US20030191292A1/en
Priority to US11/064,770 priority patent/US20050203285A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/644Coagulation factor IXa (3.4.21.22)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/37Factors VIII
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4717Plasma globulins, lactoglobulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121Serpins
    • C07K14/8128Antithrombin III
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02Recovery or purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21022Coagulation factor IXa (3.4.21.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Water Supply & Treatment (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Glass Compositions (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SE9500724A 1994-06-23 1995-02-24 Filtrering SE9500724D0 (sv)

Priority Applications (21)

Application Number Priority Date Filing Date Title
SE9500724A SE9500724D0 (sv) 1994-06-23 1995-02-24 Filtrering
AT95923651T ATE212354T1 (de) 1994-06-23 1995-06-22 Filtrationsverfahren zur entfehrnung von viren aus virus-kontaminierten wasserigen lösungen
EP95923651A EP0796269B1 (de) 1994-06-23 1995-06-22 Filtrationsverfahren zur entfehrnung von viren aus virus-kontaminierten wasserigen lösungen
DE69525176T DE69525176T2 (de) 1994-06-23 1995-06-22 Filtrationsverfahren zur entfehrnung von viren aus virus-kontaminierten wasserigen lösungen
US08/750,664 US6486306B1 (en) 1994-06-23 1995-06-22 Filtration
DE0796269T DE796269T1 (de) 1994-06-23 1995-06-22 Filtration
PCT/SE1995/000777 WO1996000237A1 (en) 1994-06-23 1995-06-22 Filtration
NZ288789A NZ288789A (en) 1994-06-23 1995-06-22 Virus filtration solution
MX9606639A MX9606639A (es) 1994-06-23 1995-06-22 Filtracion.
CA002192683A CA2192683C (en) 1994-06-23 1995-06-22 Filtration
JP50306296A JP3676370B2 (ja) 1994-06-23 1995-06-22 濾過
ES95923651T ES2105992T3 (es) 1994-06-23 1995-06-22 Procedimiento de filtracion para la eliminacion de virus de una solucion acuosa contaminada con virus.
DK95923651T DK0796269T3 (da) 1994-06-23 1995-06-22 Filtreringsmetode til fjernelse af vira fra virusforurenede, vandige opløsninger
PT95923651T PT796269E (pt) 1994-06-23 1995-06-22 Processo de filtracao para a remocao de virus de solucoes aquosas contaminadas com virus
AU28132/95A AU682274C (en) 1994-06-23 1995-06-22 Filtration
FI965145A FI965145A0 (fi) 1994-06-23 1996-12-20 Suodatus
NO19965523A NO320952B1 (no) 1994-06-23 1996-12-20 Fremgangsmate for virusfiltrering av en losning inneholdende minst ett makromolekyl
GR970300038T GR970300038T1 (en) 1994-06-23 1997-11-28 Filtration
US09/511,953 US6399357B1 (en) 1994-06-23 2000-02-23 Filtration
US10/304,902 US20030191292A1 (en) 1994-06-23 2002-11-26 Filtration
US11/064,770 US20050203285A1 (en) 1994-06-23 2005-02-23 Filtration

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9402254A SE502820C2 (sv) 1994-06-23 1994-06-23 Filtrering
SE9500724A SE9500724D0 (sv) 1994-06-23 1995-02-24 Filtrering

Publications (1)

Publication Number Publication Date
SE9500724D0 true SE9500724D0 (sv) 1995-02-24

Family

ID=26662085

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9500724A SE9500724D0 (sv) 1994-06-23 1995-02-24 Filtrering

Country Status (16)

Country Link
US (4) US6486306B1 (de)
EP (1) EP0796269B1 (de)
JP (1) JP3676370B2 (de)
AT (1) ATE212354T1 (de)
CA (1) CA2192683C (de)
DE (2) DE69525176T2 (de)
DK (1) DK0796269T3 (de)
ES (1) ES2105992T3 (de)
FI (1) FI965145A0 (de)
GR (1) GR970300038T1 (de)
MX (1) MX9606639A (de)
NO (1) NO320952B1 (de)
NZ (1) NZ288789A (de)
PT (1) PT796269E (de)
SE (1) SE9500724D0 (de)
WO (1) WO1996000237A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9500724D0 (sv) * 1994-06-23 1995-02-24 Pharmacia Ab Filtrering
SE9500778D0 (sv) 1995-03-03 1995-03-03 Pharmacia Ab Process for producing a protein
SE9603068D0 (sv) 1996-08-23 1996-08-23 Pharmacia & Upjohn Ab Process for purifying a protein
SE9603303D0 (sv) 1996-09-11 1996-09-11 Pharmacia & Upjohn Ab Process for purifying a protein
EP0860444A1 (de) * 1997-02-24 1998-08-26 Stichting Centraal Laboratorium van de Bloedtransfusiedienst van het Nederlandse Rode Kruis (CLB) Methode zur Entfernung von Viren aus Proteinlösungen
US6045588A (en) 1997-04-29 2000-04-04 Whirlpool Corporation Non-aqueous washing apparatus and method
US6096872A (en) * 1997-10-14 2000-08-01 Ortho Diagnostic Systems, Inc. Viral clearance process
FR2772381B1 (fr) * 1997-12-15 2001-06-08 Lab Francais Du Fractionnement Procede de preparation par filtration d'une solution de facteur viii securisee viralement
US6861001B2 (en) * 1999-12-02 2005-03-01 The General Hospital Corporation Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon
CN100507567C (zh) 2002-05-23 2009-07-01 奥索临床诊断有限公司 朊病毒蛋白的去除
CA2489123C (en) 2002-06-14 2011-03-15 Centocor, Inc. Use of a clathrate modifier to promote passage of proteins during nanofiltration
JP2004099506A (ja) * 2002-09-09 2004-04-02 Mitsubishi Rayon Co Ltd アミノ酸アミドの製造方法
WO2004089402A1 (ja) * 2003-04-09 2004-10-21 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute アルブミン製剤の製造方法
JP4558652B2 (ja) * 2003-06-20 2010-10-06 マイクロビクス・バイオシステムズ・インコーポレイテツド ウイルス生産の改善
CN100398642C (zh) * 2003-06-20 2008-07-02 迈克必斯生物系统公司 病毒生产的改进
FR2861395B1 (fr) 2003-10-23 2006-02-17 Lab Francais Du Fractionnement Facteur viii viralement securise a faible teneur en multimeres superieurs
US7695524B2 (en) 2003-10-31 2010-04-13 Whirlpool Corporation Non-aqueous washing machine and methods
US7739891B2 (en) 2003-10-31 2010-06-22 Whirlpool Corporation Fabric laundering apparatus adapted for using a select rinse fluid
EP2275432A1 (de) * 2003-12-01 2011-01-19 Novo Nordisk Health Care AG Nanofiltration von Faktor VII Lösungen zur Entfernung von Viren
JP2007522814A (ja) 2004-02-23 2007-08-16 クルセル ホランド ベー ヴェー ウイルスの精製方法
FR2866890B1 (fr) * 2004-02-27 2008-04-04 Lab Francais Du Fractionnement Procede de purification d'albumine comprenant une etape de nanofiltration, solution et composition a usage therapeutique la contenant
EP1740757A1 (de) 2004-04-29 2007-01-10 Unilever N.V. Chemisches reinigungsverfahren
US7141171B2 (en) * 2004-05-21 2006-11-28 Wisconsin Alumni Research Foundation Membrane cascade-based separation
AU2005229674B2 (en) 2004-11-18 2010-11-04 Kedrion Melville Inc. Low concentration solvent/detergent process of immuneglobulin with pre-treatment
AU2006233800B2 (en) 2005-04-11 2011-07-07 Crucell Holland B.V. Virus purification using ultrafiltration
US7966684B2 (en) 2005-05-23 2011-06-28 Whirlpool Corporation Methods and apparatus to accelerate the drying of aqueous working fluids
ES2775974T3 (es) * 2006-06-26 2020-07-28 Omrix Biopharmaceuticals Inc Eliminación de virus por nanofiltración
CA2690673C (en) * 2007-06-15 2013-04-23 Amgen Inc. Methods of treating cell culture media for use in a bioreactor
KR100870423B1 (ko) * 2007-06-27 2008-11-26 주식회사 하이닉스반도체 반도체메모리소자
US7989593B1 (en) 2010-05-27 2011-08-02 Bing Lou Wong Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof
US8048856B1 (en) 2010-06-23 2011-11-01 Billion King, Ltd. Treatment methods using a heat stable oxygen carrier-containing pharmaceutical composition
US7932356B1 (en) 2010-06-23 2011-04-26 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical composition
US8084581B1 (en) 2011-04-29 2011-12-27 Bing Lou Wong Method for removing unmodified hemoglobin from cross-linked hemoglobin solutions including polymeric hemoglobin with a high temperature short time heat treatment apparatus
US9359397B2 (en) 2011-06-24 2016-06-07 Asahi Kasei Medical Co., Ltd. Method for manufacturing protein drug
US20130052232A1 (en) 2011-08-31 2013-02-28 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing composition facilating beta-beta cross-linking
US9294158B2 (en) 2012-08-07 2016-03-22 Broadcom Corporation Broadcast audio service
KR102437202B1 (ko) 2013-08-08 2022-08-29 시에스엘 리미티드 오염 제거 방법
WO2018053384A1 (en) 2016-09-19 2018-03-22 Asgco Manufacturing, Inc. Return idler trainer

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US3870801A (en) 1968-08-09 1975-03-11 Lever Brothers Ltd Fluid aqueous protein compositions and food products prepared therefrom
US3919044A (en) 1973-03-28 1975-11-11 Armour Pharma Processes for concentrating and purifying viruses and viral antigens
US3874999A (en) 1973-10-31 1975-04-01 American Cyanamid Co Process for the purification of virus vaccine
CA1099576A (en) 1978-03-23 1981-04-21 Chester D. Myers Improved process for isolation of proteins
US4473494A (en) 1983-05-04 1984-09-25 The United States Of America As Represented By The Secretary Of The Army Preparation of stroma-free, non-heme protein-free hemoglobin
US4684723A (en) * 1985-09-11 1987-08-04 Miles Laboratories, Inc. Method of separating proteins from aqueous solutions
JPH0720986B2 (ja) 1985-10-07 1995-03-08 日本ケミカルリサ−チ株式会社 生理活性物質の製造法
AU605901B2 (en) * 1987-09-11 1991-01-24 Ares Trading S.A. Purification process
RU1781355C (ru) * 1990-04-23 1992-12-15 В.П.Широбоков, Л.Я.Палиенко, А.И.Евтушенко, Л.А Коптюх, Ю.В.Загороднюк и К.Д Стеценко Фильтрующий материал
US5017292A (en) 1990-05-10 1991-05-21 Millipore Corporation Membrane, process and system for isolating virus from solution
US5076933A (en) 1990-06-29 1991-12-31 Coulter Corporation Process and apparatus for removal of dna and viruses
US5221483A (en) * 1990-06-29 1993-06-22 Coulter Corporation Process and apparatus for removal of DNA, viruses and endotoxins
SE9301582D0 (sv) 1993-05-07 1993-05-07 Kabi Pharmacia Ab Purification of plasma proteins
SE9500724D0 (sv) * 1994-06-23 1995-02-24 Pharmacia Ab Filtrering

Also Published As

Publication number Publication date
DE69525176D1 (de) 2002-03-14
ES2105992T1 (es) 1997-11-01
NO965523D0 (no) 1996-12-20
EP0796269A1 (de) 1997-09-24
ES2105992T3 (es) 2002-09-16
FI965145A (fi) 1996-12-20
DE796269T1 (de) 1998-01-02
ES2105992T2 (es) 1997-11-01
NO320952B1 (no) 2006-02-20
PT796269E (pt) 2002-06-28
US6399357B1 (en) 2002-06-04
CA2192683A1 (en) 1996-01-04
US20050203285A1 (en) 2005-09-15
MX9606639A (es) 1997-03-29
US6486306B1 (en) 2002-11-26
JPH10502074A (ja) 1998-02-24
FI965145A0 (fi) 1996-12-20
CA2192683C (en) 2005-07-05
WO1996000237A1 (en) 1996-01-04
DE69525176T2 (de) 2002-06-27
ATE212354T1 (de) 2002-02-15
NO965523L (no) 1996-12-20
GR970300038T1 (en) 1997-11-28
AU682274B2 (en) 1997-09-25
AU2813295A (en) 1996-01-19
US20030191292A1 (en) 2003-10-09
JP3676370B2 (ja) 2005-07-27
EP0796269B1 (de) 2002-01-23
NZ288789A (en) 1997-12-19
DK0796269T3 (da) 2002-05-06

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