PT796269E - Processo de filtracao para a remocao de virus de solucoes aquosas contaminadas com virus - Google Patents

Processo de filtracao para a remocao de virus de solucoes aquosas contaminadas com virus

Info

Publication number
PT796269E
PT796269E PT95923651T PT95923651T PT796269E PT 796269 E PT796269 E PT 796269E PT 95923651 T PT95923651 T PT 95923651T PT 95923651 T PT95923651 T PT 95923651T PT 796269 E PT796269 E PT 796269E
Authority
PT
Portugal
Prior art keywords
viruses
removal
aqueous solutions
filtration process
filtering
Prior art date
Application number
PT95923651T
Other languages
English (en)
Inventor
Stefan Winge
Original Assignee
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26662085&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT796269(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from SE9402254A external-priority patent/SE502820C2/sv
Application filed by Biovitrum Ab filed Critical Biovitrum Ab
Publication of PT796269E publication Critical patent/PT796269E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4717—Plasma globulins, lactoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8128—Antithrombin III
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Water Supply & Treatment (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Glass Compositions (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PT95923651T 1994-06-23 1995-06-22 Processo de filtracao para a remocao de virus de solucoes aquosas contaminadas com virus PT796269E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9402254A SE502820C2 (sv) 1994-06-23 1994-06-23 Filtrering
SE9500724A SE9500724D0 (sv) 1994-06-23 1995-02-24 Filtrering

Publications (1)

Publication Number Publication Date
PT796269E true PT796269E (pt) 2002-06-28

Family

ID=26662085

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95923651T PT796269E (pt) 1994-06-23 1995-06-22 Processo de filtracao para a remocao de virus de solucoes aquosas contaminadas com virus

Country Status (16)

Country Link
US (4) US6486306B1 (pt)
EP (1) EP0796269B1 (pt)
JP (1) JP3676370B2 (pt)
AT (1) ATE212354T1 (pt)
CA (1) CA2192683C (pt)
DE (2) DE796269T1 (pt)
DK (1) DK0796269T3 (pt)
ES (1) ES2105992T3 (pt)
FI (1) FI965145A (pt)
GR (1) GR970300038T1 (pt)
MX (1) MX9606639A (pt)
NO (1) NO320952B1 (pt)
NZ (1) NZ288789A (pt)
PT (1) PT796269E (pt)
SE (1) SE9500724D0 (pt)
WO (1) WO1996000237A1 (pt)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9500724D0 (sv) * 1994-06-23 1995-02-24 Pharmacia Ab Filtrering
SE9500778D0 (sv) 1995-03-03 1995-03-03 Pharmacia Ab Process for producing a protein
SE9603068D0 (sv) 1996-08-23 1996-08-23 Pharmacia & Upjohn Ab Process for purifying a protein
SE9603303D0 (sv) 1996-09-11 1996-09-11 Pharmacia & Upjohn Ab Process for purifying a protein
EP0860444A1 (en) * 1997-02-24 1998-08-26 Stichting Centraal Laboratorium van de Bloedtransfusiedienst van het Nederlandse Rode Kruis (CLB) Method for removing viruses from a protein solution
US6045588A (en) 1997-04-29 2000-04-04 Whirlpool Corporation Non-aqueous washing apparatus and method
US6096872A (en) * 1997-10-14 2000-08-01 Ortho Diagnostic Systems, Inc. Viral clearance process
FR2772381B1 (fr) † 1997-12-15 2001-06-08 Lab Francais Du Fractionnement Procede de preparation par filtration d'une solution de facteur viii securisee viralement
WO2001040448A1 (en) * 1999-12-02 2001-06-07 The General Hospital Corporation Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon
AU2003241596B2 (en) 2002-05-23 2010-01-21 Kedrion Melville Inc. Capture, concentration and quantitation of abnormal prior protein from biological fluids using depth filtration
US6773600B2 (en) 2002-06-14 2004-08-10 Cantocor, Inc. Use of a clathrate modifier, to promote passage of proteins during nanofiltration
JP2004099506A (ja) * 2002-09-09 2004-04-02 Mitsubishi Rayon Co Ltd アミノ酸アミドの製造方法
AU2004228847B2 (en) * 2003-04-09 2010-06-17 Km Biologics Co., Ltd. Process for producing albumin preparation
US7270990B2 (en) * 2003-06-20 2007-09-18 Microbix Biosystems, Inc. Virus production
CN100398642C (zh) * 2003-06-20 2008-07-02 迈克必斯生物系统公司 病毒生产的改进
FR2861395B1 (fr) 2003-10-23 2006-02-17 Lab Francais Du Fractionnement Facteur viii viralement securise a faible teneur en multimeres superieurs
US7695524B2 (en) 2003-10-31 2010-04-13 Whirlpool Corporation Non-aqueous washing machine and methods
US7739891B2 (en) 2003-10-31 2010-06-22 Whirlpool Corporation Fabric laundering apparatus adapted for using a select rinse fluid
EP1711513B1 (en) * 2003-12-01 2014-07-02 Novo Nordisk Health Care AG Nanofiltration of factor vii solutions to remove virus
NZ548495A (en) 2004-02-23 2009-05-31 Crucell Holland Bv Virus purification methods
FR2866890B1 (fr) * 2004-02-27 2008-04-04 Lab Francais Du Fractionnement Procede de purification d'albumine comprenant une etape de nanofiltration, solution et composition a usage therapeutique la contenant
WO2005106105A1 (en) 2004-04-29 2005-11-10 Unilever N.V. Dry cleaning method
WO2005113119A1 (en) * 2004-05-21 2005-12-01 Wisconsin Alumni Research Foundation Membrane cascade-based separation
AU2005229674B2 (en) 2004-11-18 2010-11-04 Kedrion Melville Inc. Low concentration solvent/detergent process of immuneglobulin with pre-treatment
DK1869171T4 (en) 2005-04-11 2016-01-18 Crucell Holland Bv Virus cleaning using ultrafiltration
US7966684B2 (en) 2005-05-23 2011-06-28 Whirlpool Corporation Methods and apparatus to accelerate the drying of aqueous working fluids
CA2655897C (en) * 2006-06-26 2015-09-29 Omrix Biopharmaceuticals Inc. Virus removal by nanofiltration
EP2173861B2 (en) * 2007-06-15 2017-02-22 Amgen Inc. Methods of treating cell culture media for use in a bioreactor
KR100870423B1 (ko) * 2007-06-27 2008-11-26 주식회사 하이닉스반도체 반도체메모리소자
US7989593B1 (en) 2010-05-27 2011-08-02 Bing Lou Wong Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof
US8048856B1 (en) 2010-06-23 2011-11-01 Billion King, Ltd. Treatment methods using a heat stable oxygen carrier-containing pharmaceutical composition
US7932356B1 (en) 2010-06-23 2011-04-26 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical composition
US8084581B1 (en) 2011-04-29 2011-12-27 Bing Lou Wong Method for removing unmodified hemoglobin from cross-linked hemoglobin solutions including polymeric hemoglobin with a high temperature short time heat treatment apparatus
WO2012176876A1 (ja) * 2011-06-24 2012-12-27 旭化成メディカル株式会社 蛋白製剤の製造方法
US20130052232A1 (en) 2011-08-31 2013-02-28 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing composition facilating beta-beta cross-linking
US9294158B2 (en) 2012-08-07 2016-03-22 Broadcom Corporation Broadcast audio service
EP3418290A1 (en) 2013-08-08 2018-12-26 CSL Ltd. Contaminant removal method
WO2018053384A1 (en) 2016-09-19 2018-03-22 Asgco Manufacturing, Inc. Return idler trainer

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US3870801A (en) 1968-08-09 1975-03-11 Lever Brothers Ltd Fluid aqueous protein compositions and food products prepared therefrom
US3919044A (en) 1973-03-28 1975-11-11 Armour Pharma Processes for concentrating and purifying viruses and viral antigens
US3874999A (en) 1973-10-31 1975-04-01 American Cyanamid Co Process for the purification of virus vaccine
CA1099576A (en) 1978-03-23 1981-04-21 Chester D. Myers Improved process for isolation of proteins
US4473494A (en) 1983-05-04 1984-09-25 The United States Of America As Represented By The Secretary Of The Army Preparation of stroma-free, non-heme protein-free hemoglobin
US4684723A (en) * 1985-09-11 1987-08-04 Miles Laboratories, Inc. Method of separating proteins from aqueous solutions
JPH0720986B2 (ja) * 1985-10-07 1995-03-08 日本ケミカルリサ−チ株式会社 生理活性物質の製造法
AU605901B2 (en) * 1987-09-11 1991-01-24 Ares Trading S.A. Purification process
RU1781355C (ru) * 1990-04-23 1992-12-15 В.П.Широбоков, Л.Я.Палиенко, А.И.Евтушенко, Л.А Коптюх, Ю.В.Загороднюк и К.Д Стеценко Фильтрующий материал
US5017292A (en) 1990-05-10 1991-05-21 Millipore Corporation Membrane, process and system for isolating virus from solution
US5221483A (en) * 1990-06-29 1993-06-22 Coulter Corporation Process and apparatus for removal of DNA, viruses and endotoxins
US5076933A (en) 1990-06-29 1991-12-31 Coulter Corporation Process and apparatus for removal of dna and viruses
SE9301582D0 (sv) 1993-05-07 1993-05-07 Kabi Pharmacia Ab Purification of plasma proteins
SE9500724D0 (sv) * 1994-06-23 1995-02-24 Pharmacia Ab Filtrering

Also Published As

Publication number Publication date
JPH10502074A (ja) 1998-02-24
EP0796269B1 (en) 2002-01-23
NO965523L (no) 1996-12-20
SE9500724D0 (sv) 1995-02-24
US6399357B1 (en) 2002-06-04
ES2105992T1 (es) 1997-11-01
ATE212354T1 (de) 2002-02-15
MX9606639A (es) 1997-03-29
JP3676370B2 (ja) 2005-07-27
DE69525176T2 (de) 2002-06-27
DE796269T1 (de) 1998-01-02
US20030191292A1 (en) 2003-10-09
US6486306B1 (en) 2002-11-26
NO965523D0 (no) 1996-12-20
ES2105992T3 (es) 2002-09-16
CA2192683C (en) 2005-07-05
CA2192683A1 (en) 1996-01-04
FI965145A0 (fi) 1996-12-20
AU682274B2 (en) 1997-09-25
GR970300038T1 (en) 1997-11-28
WO1996000237A1 (en) 1996-01-04
DK0796269T3 (da) 2002-05-06
FI965145A (fi) 1996-12-20
EP0796269A1 (en) 1997-09-24
NZ288789A (en) 1997-12-19
ES2105992T2 (es) 1997-11-01
DE69525176D1 (de) 2002-03-14
AU2813295A (en) 1996-01-19
NO320952B1 (no) 2006-02-20
US20050203285A1 (en) 2005-09-15

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