SE9404468D0 - Powder formulations - Google Patents

Powder formulations

Info

Publication number
SE9404468D0
SE9404468D0 SE9404468A SE9404468A SE9404468D0 SE 9404468 D0 SE9404468 D0 SE 9404468D0 SE 9404468 A SE9404468 A SE 9404468A SE 9404468 A SE9404468 A SE 9404468A SE 9404468 D0 SE9404468 D0 SE 9404468D0
Authority
SE
Sweden
Prior art keywords
powder formulations
medically useful
formulation
polypeptide
useful polypeptide
Prior art date
Application number
SE9404468A
Other languages
English (en)
Swedish (sv)
Inventor
Kjell Baeckstroem
Ann Johansson
Helena Linden
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9404468A priority Critical patent/SE9404468D0/xx
Publication of SE9404468D0 publication Critical patent/SE9404468D0/xx
Priority to ZA9510753A priority patent/ZA9510753B/xx
Priority to AT95942342T priority patent/ATE220900T1/de
Priority to JP8519731A priority patent/JPH10510828A/ja
Priority to PL95320751A priority patent/PL183944B1/pl
Priority to DE69533294T priority patent/DE69533294T2/de
Priority to CZ19971946A priority patent/CZ288487B6/cs
Priority to ES01130870T priority patent/ES2222306T3/es
Priority to RU97112496A priority patent/RU2144819C1/ru
Priority to IL11645995A priority patent/IL116459A/en
Priority to PCT/SE1995/001541 priority patent/WO1996019207A1/en
Priority to PT01130870T priority patent/PT1224929E/pt
Priority to EP01130870A priority patent/EP1224929B1/en
Priority to SK812-97A priority patent/SK283147B6/sk
Priority to KR1019970704254A priority patent/KR100391873B1/ko
Priority to EE9700135A priority patent/EE03381B1/xx
Priority to BR9510422A priority patent/BR9510422A/pt
Priority to US08/617,753 priority patent/US6004574A/en
Priority to DK95942342T priority patent/DK0799030T3/da
Priority to CA002206803A priority patent/CA2206803A1/en
Priority to AT01130870T priority patent/ATE271382T1/de
Priority to DK01130870T priority patent/DK1224929T3/da
Priority to UA97073876A priority patent/UA44757C2/uk
Priority to HU9800493A priority patent/HU217975B/hu
Priority to DE69527542T priority patent/DE69527542T2/de
Priority to CN95196965A priority patent/CN1080114C/zh
Priority to NZ298168A priority patent/NZ298168A/en
Priority to MYPI95003942A priority patent/MY114211A/en
Priority to ES95942342T priority patent/ES2177674T3/es
Priority to TW084113557A priority patent/TW474823B/zh
Priority to EP95942342A priority patent/EP0799030B1/en
Priority to PT95942342T priority patent/PT799030E/pt
Priority to AU43592/96A priority patent/AU702898B2/en
Priority to TR95/01632A priority patent/TR199501632A1/xx
Priority to ARP950100706A priority patent/AR002261A1/es
Priority to SA95160484A priority patent/SA95160484B1/ar
Priority to IS4495A priority patent/IS1848B/is
Priority to NO19972660A priority patent/NO315966B1/no
Priority to MXPA/A/1997/004551A priority patent/MXPA97004551A/xx
Priority to FI972654A priority patent/FI972654A/fi
Priority to HK98102788A priority patent/HK1003619A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
SE9404468A 1994-12-22 1994-12-22 Powder formulations SE9404468D0 (sv)

Priority Applications (41)

Application Number Priority Date Filing Date Title
SE9404468A SE9404468D0 (sv) 1994-12-22 1994-12-22 Powder formulations
ZA9510753A ZA9510753B (en) 1994-12-22 1995-12-18 Power formulations
AT01130870T ATE271382T1 (de) 1994-12-22 1995-12-19 Pulverformulierungen, die melezitose als verdünnungsmittel enthalten
DK95942342T DK0799030T3 (da) 1994-12-22 1995-12-19 Pulverformuleringer indeholdende melezitose som fortyndingsmiddel
EP95942342A EP0799030B1 (en) 1994-12-22 1995-12-19 Powder formulations containing melezitose as a diluent
PL95320751A PL183944B1 (pl) 1994-12-22 1995-12-19 Preparaty proszkowe przydatnych medycznie polipeptydów i sposób ich wytwarzania
DE69533294T DE69533294T2 (de) 1994-12-22 1995-12-19 Pulverformulierungen, die Melezitose als Verdünnungsmittel enthalten
CZ19971946A CZ288487B6 (en) 1994-12-22 1995-12-19 Powder formulation for the administration of medically useful polypeptides and process for preparing thereof
ES01130870T ES2222306T3 (es) 1994-12-22 1995-12-19 Formulaciones en polvo que contienen melezitosa como diluyente.
RU97112496A RU2144819C1 (ru) 1994-12-22 1995-12-19 Порошкообразные препараты, содержащие мелецитозу в качестве разбавителя
IL11645995A IL116459A (en) 1994-12-22 1995-12-19 Powdery preparations containing a medically effective polypeptide, and a method for their preparation
PCT/SE1995/001541 WO1996019207A1 (en) 1994-12-22 1995-12-19 Powder formulations containing melezitose as a diluent
PT01130870T PT1224929E (pt) 1994-12-22 1995-12-19 Formulacoes em po contendo melezitose como diluente
EP01130870A EP1224929B1 (en) 1994-12-22 1995-12-19 Powder formulations containing melezitose as a diluent
SK812-97A SK283147B6 (sk) 1994-12-22 1995-12-19 Práškový prostriedok na aplikáciu liečivých peptidov, spôsob jeho výroby a jeho použitie
KR1019970704254A KR100391873B1 (ko) 1994-12-22 1995-12-19 희석제로서멜레지토스를함유하는분말제제
UA97073876A UA44757C2 (uk) 1994-12-22 1995-12-19 Порошкоподібний препарат для введення медично корисних поліпептидів шляхом інгаляції, спосіб виробництва порошкоподібного препарату та спосіб лікування пацієнта
BR9510422A BR9510422A (pt) 1994-12-22 1995-12-19 Formulação em pó para administração de polipeptídeos medicamente úteis uso do pó e processos para fabricação da formulação e para tratamento de um paciente carente de terapia
US08/617,753 US6004574A (en) 1994-12-22 1995-12-19 Powder formulations containing melezitose as a diluent
AT95942342T ATE220900T1 (de) 1994-12-22 1995-12-19 Pulverformulierungen die melizitose als verdünnungsmittel enthalten
CA002206803A CA2206803A1 (en) 1994-12-22 1995-12-19 Powder formulations containing melezitose as a diluent
DK01130870T DK1224929T3 (da) 1994-12-22 1995-12-19 Pulverformuleringer indeholdende melezitose som et fortyndingsmiddel
AU43592/96A AU702898B2 (en) 1994-12-22 1995-12-19 Powder formulations containing melezitose as a diluent
EE9700135A EE03381B1 (et) 1994-12-22 1995-12-19 Pulbrilised ravimvormid, mis sisaldavad lahjendajana melesitoosi
HU9800493A HU217975B (hu) 1994-12-22 1995-12-19 Polipeptidet higítóként melezitózt tartalmazó inhalációs porkészítmények és eljárás előállításukra
DE69527542T DE69527542T2 (de) 1994-12-22 1995-12-19 Pulverformulierungen die melizitose als verdünnungsmittel enthalten
CN95196965A CN1080114C (zh) 1994-12-22 1995-12-19 含有松三糖作为稀释剂的粉剂
NZ298168A NZ298168A (en) 1994-12-22 1995-12-19 Powdered medicaments for administering polypeptides; contain melezitose as diluent
MYPI95003942A MY114211A (en) 1994-12-22 1995-12-19 Powder formulations containing melezitose as a diluent
ES95942342T ES2177674T3 (es) 1994-12-22 1995-12-19 Formulaciones de polvos que contienen melezitosa como un diluyente.
TW084113557A TW474823B (en) 1994-12-22 1995-12-19 Powder formulations containing, as a diluent, D-melezitose (Α-D-melezitose), β-D-glucopyranoside, O-Α-D-glucopyranosyl-1,3-β-D-fructofuranosyl (β-D-melezitose) or isomelezitose
JP8519731A JPH10510828A (ja) 1994-12-22 1995-12-19 賦形剤としてメレチトースを含む粉末製剤
PT95942342T PT799030E (pt) 1994-12-22 1995-12-19 Formulacoes em po contendo melezitose como diluente
ARP950100706A AR002261A1 (es) 1994-12-22 1995-12-21 Composicion en polvo para la administracion por inhalacion de polipeptidos utiles en medicina, metodos para la manufactura de dicha composicion, y uso de la composicion para la manufactura de un medicamento para el tratamietno de enfermedades a traves del tracto respiratorio
TR95/01632A TR199501632A1 (tr) 1994-12-22 1995-12-21 Toz formülasyonlari.
SA95160484A SA95160484B1 (ar) 1994-12-22 1995-12-30 مستحضرات مساحيق تحتوي على مليزيتوز melezitose كمادة مخففة
IS4495A IS1848B (is) 1994-12-22 1997-06-03 Duftblöndur sem innihalda melesítósa sem þynningarefni
NO19972660A NO315966B1 (no) 1994-12-22 1997-06-10 Pulverformulering inneholdende melezitose som et fortynningsmiddel, fremgangsmåter for dens fremstilling, og anvendelse derav
MXPA/A/1997/004551A MXPA97004551A (en) 1994-12-22 1997-06-18 Formulations in powder containing melecitose as a diluye
FI972654A FI972654A (fi) 1994-12-22 1997-06-19 Meletsitoosia laimentimena sisältävät jauhekoostumukset
HK98102788A HK1003619A1 (en) 1994-12-22 1998-04-02 Powder formulations containing melezitose as a diluent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9404468A SE9404468D0 (sv) 1994-12-22 1994-12-22 Powder formulations

Publications (1)

Publication Number Publication Date
SE9404468D0 true SE9404468D0 (sv) 1994-12-22

Family

ID=20396435

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9404468A SE9404468D0 (sv) 1994-12-22 1994-12-22 Powder formulations

Country Status (34)

Country Link
US (1) US6004574A (fi)
EP (2) EP0799030B1 (fi)
JP (1) JPH10510828A (fi)
KR (1) KR100391873B1 (fi)
CN (1) CN1080114C (fi)
AR (1) AR002261A1 (fi)
AT (2) ATE220900T1 (fi)
AU (1) AU702898B2 (fi)
BR (1) BR9510422A (fi)
CA (1) CA2206803A1 (fi)
CZ (1) CZ288487B6 (fi)
DE (2) DE69533294T2 (fi)
DK (2) DK1224929T3 (fi)
EE (1) EE03381B1 (fi)
ES (2) ES2222306T3 (fi)
FI (1) FI972654A (fi)
HK (1) HK1003619A1 (fi)
HU (1) HU217975B (fi)
IL (1) IL116459A (fi)
IS (1) IS1848B (fi)
MY (1) MY114211A (fi)
NO (1) NO315966B1 (fi)
NZ (1) NZ298168A (fi)
PL (1) PL183944B1 (fi)
PT (2) PT1224929E (fi)
RU (1) RU2144819C1 (fi)
SA (1) SA95160484B1 (fi)
SE (1) SE9404468D0 (fi)
SK (1) SK283147B6 (fi)
TR (1) TR199501632A1 (fi)
TW (1) TW474823B (fi)
UA (1) UA44757C2 (fi)
WO (1) WO1996019207A1 (fi)
ZA (1) ZA9510753B (fi)

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US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
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DK0799030T3 (da) 2002-09-16
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IL116459A (en) 2002-11-10
EP0799030A1 (en) 1997-10-08
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ZA9510753B (en) 1996-06-24
EP0799030B1 (en) 2002-07-24
NO315966B1 (no) 2003-11-24
ES2177674T3 (es) 2002-12-16
ES2222306T3 (es) 2005-02-01
IS1848B (is) 2003-02-07
CN1171049A (zh) 1998-01-21
EP1224929A2 (en) 2002-07-24
CZ194697A3 (en) 1997-10-15
SA95160484B1 (ar) 2005-10-01
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FI972654A0 (fi) 1997-06-19
US6004574A (en) 1999-12-21
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UA44757C2 (uk) 2002-03-15
DE69527542T2 (de) 2003-01-30
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NO972660D0 (no) 1997-06-10
ATE220900T1 (de) 2002-08-15
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CA2206803A1 (en) 1996-06-27
HUT77648A (hu) 1998-07-28
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DE69533294D1 (de) 2004-08-26
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