SE8400445L - Nya farmaceutiska aktiva 1,2,3,4,4a,5,10,10a-oktahydrobenso(g)kinolinderivat, deras framstellning och anvendning - Google Patents

Nya farmaceutiska aktiva 1,2,3,4,4a,5,10,10a-oktahydrobenso(g)kinolinderivat, deras framstellning och anvendning

Info

Publication number
SE8400445L
SE8400445L SE8400445A SE8400445A SE8400445L SE 8400445 L SE8400445 L SE 8400445L SE 8400445 A SE8400445 A SE 8400445A SE 8400445 A SE8400445 A SE 8400445A SE 8400445 L SE8400445 L SE 8400445L
Authority
SE
Sweden
Prior art keywords
octahydrobenso
preparation
quinoline derivatives
new pharmaceutical
pharmaceutical activities
Prior art date
Application number
SE8400445A
Other languages
English (en)
Swedish (sv)
Other versions
SE8400445D0 (sv
Inventor
M P Seiler
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8400445D0 publication Critical patent/SE8400445D0/xx
Publication of SE8400445L publication Critical patent/SE8400445L/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/08—Aza-anthracenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8400445A 1983-02-01 1984-01-30 Nya farmaceutiska aktiva 1,2,3,4,4a,5,10,10a-oktahydrobenso(g)kinolinderivat, deras framstellning och anvendning SE8400445L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH56083 1983-02-01

Publications (2)

Publication Number Publication Date
SE8400445D0 SE8400445D0 (sv) 1984-01-30
SE8400445L true SE8400445L (sv) 1984-08-02

Family

ID=4189841

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8400445A SE8400445L (sv) 1983-02-01 1984-01-30 Nya farmaceutiska aktiva 1,2,3,4,4a,5,10,10a-oktahydrobenso(g)kinolinderivat, deras framstellning och anvendning

Country Status (17)

Country Link
US (1) US4692453A (de)
JP (1) JPS59144761A (de)
AU (1) AU571482B2 (de)
BE (1) BE898761A (de)
DE (1) DE3402601A1 (de)
DK (1) DK40984A (de)
FR (1) FR2540112B1 (de)
GB (1) GB2134515B (de)
IE (1) IE56653B1 (de)
IL (1) IL70845A (de)
IT (1) IT1199056B (de)
LU (1) LU85191A1 (de)
NL (1) NL8400259A (de)
NZ (1) NZ206981A (de)
PH (1) PH22782A (de)
SE (1) SE8400445L (de)
ZA (1) ZA84757B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT393997B (de) * 1983-06-22 1992-01-10 Heidelberger Druckmasch Ag Vorrichtung zur entnahme von bedruckten bogen fuer deren begutachtung
ATE152708T1 (de) * 1989-07-13 1997-05-15 Upjohn Co (1,2n) und (3,2n)-karbozyklische-2-amino- tetralinderivate
US4939259A (en) * 1989-07-24 1990-07-03 Eli Lilly And Company 2-oxo-pyrido[2,3-g]quinoline derivatives
DE4114325A1 (de) * 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
EP0586553A1 (de) * 1991-05-20 1994-03-16 The Upjohn Company Carboxamido-(3,2n)-carbocyclische-2-amino-tetralinderivate
US8129530B2 (en) * 2007-08-31 2012-03-06 H. Lundbeck A/S Catecholamine derivatives and prodrugs thereof
EP2303851A1 (de) * 2008-06-27 2011-04-06 H. Lundbeck A/S Neue phenolische und katecholische amine und prodrugs davon
US10729710B2 (en) 2017-11-24 2020-08-04 H. Lundbeck A/S Catecholamine prodrugs for use in the treatment of Parkinson's disease
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
EP3972959A1 (de) 2019-05-21 2022-03-30 H. Lundbeck A/S Neue catecholamin-prodrugs zur verwendung in der behandlung von morbus parkinson
EP3972600A1 (de) 2019-05-21 2022-03-30 H. Lundbeck A/S Catecholamin-carbamat-prodrugs zur verwendung bei der behandlung von morbus parkinson
US12319710B2 (en) 2019-05-21 2025-06-03 H. Lundbeck A/S Catecholamine prodrugs for use in the treatment of Parkinson's diseases
WO2020234274A1 (en) 2019-05-21 2020-11-26 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of parkinson's disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639411A (en) * 1968-05-09 1972-02-01 Sterling Drug Inc 1-substituted-2-(phenyl or benzyl)-3- or 3 3 - piperidine(mono or dicarboxylic) acids and esters thereo fand octahydrobenzo(g) - quinolines and hexahydro-5h-inden (12-b)pyridines produced therefrom
US3839338A (en) * 1968-05-09 1974-10-01 W Michne 1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO{8 g{9 QUINOLINES
US3898235A (en) * 1970-12-02 1975-08-05 Sterling Drug Inc Octahydrobenzo {8 g{9 {0 quinolines and hexahydroindeno {8 1,2,b{9 {0 pyridines
ATE56958T1 (de) * 1981-10-16 1990-10-15 Sandoz Ag 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)chinolinderivate mit pharmazeutischer wirkung.

Also Published As

Publication number Publication date
IT8447626A1 (it) 1985-08-01
DE3402601A1 (de) 1984-08-02
BE898761A (fr) 1984-07-26
DK40984A (da) 1984-08-02
IE56653B1 (en) 1991-10-23
NZ206981A (en) 1987-03-31
FR2540112A1 (fr) 1984-08-03
AU571482B2 (en) 1988-04-21
FR2540112B1 (fr) 1986-08-29
US4692453A (en) 1987-09-08
GB2134515B (en) 1986-07-02
DK40984D0 (da) 1984-01-30
IL70845A0 (en) 1984-05-31
LU85191A1 (fr) 1984-10-24
AU2391184A (en) 1984-08-02
NL8400259A (nl) 1984-09-03
GB2134515A (en) 1984-08-15
SE8400445D0 (sv) 1984-01-30
IL70845A (en) 1986-09-30
IE840209L (en) 1984-08-01
GB8402358D0 (en) 1984-02-29
IT8447626A0 (it) 1984-02-01
IT1199056B (it) 1988-12-30
JPS59144761A (ja) 1984-08-18
ZA84757B (en) 1985-09-25
PH22782A (en) 1988-12-12

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