MX9201598A - Benzo piranona, procedimiento para su preparacion y utilizacion. - Google Patents
Benzo piranona, procedimiento para su preparacion y utilizacion.Info
- Publication number
- MX9201598A MX9201598A MX9201598A MX9201598A MX9201598A MX 9201598 A MX9201598 A MX 9201598A MX 9201598 A MX9201598 A MX 9201598A MX 9201598 A MX9201598 A MX 9201598A MX 9201598 A MX9201598 A MX 9201598A
- Authority
- MX
- Mexico
- Prior art keywords
- pct
- preparation
- piranona
- benzo
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4111861A DE4111861A1 (de) | 1991-04-11 | 1991-04-11 | Benzopyranone, verfahren zu ihrer herstellung und verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9201598A true MX9201598A (es) | 1992-10-01 |
Family
ID=6429379
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9201598A MX9201598A (es) | 1991-04-11 | 1992-04-07 | Benzo piranona, procedimiento para su preparacion y utilizacion. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5428038A (es) |
EP (1) | EP0584091B1 (es) |
JP (1) | JP3234221B2 (es) |
AT (1) | ATE147736T1 (es) |
AU (1) | AU658619B2 (es) |
CA (1) | CA2108174A1 (es) |
DE (2) | DE4111861A1 (es) |
ES (1) | ES2097908T3 (es) |
MX (1) | MX9201598A (es) |
WO (1) | WO1992018493A1 (es) |
ZA (1) | ZA922614B (es) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1048489C (zh) * | 1993-10-30 | 2000-01-19 | 山东省医学科学院药物研究所 | 抗病毒新化合物短叶苏木酚酸甲酯及其制备方法 |
CN1048488C (zh) * | 1993-10-30 | 2000-01-19 | 山东省医学科学院药物研究所 | 抗病毒新化合物去氢柯子次酸甲酯及其制备方法 |
ZA9610745B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
US7186726B2 (en) * | 1998-06-30 | 2007-03-06 | Neuromed Pharmaceuticals Ltd. | Preferentially substituted calcium channel blockers |
US6492375B2 (en) | 1998-06-30 | 2002-12-10 | Neuromed Technologies, Inc. | Partially saturated calcium channel blockers |
US20060084660A1 (en) * | 1998-06-30 | 2006-04-20 | Neuromed Technologies Inc. | Calcium channel blockers comprising two benzhydril moieties |
US20040259866A1 (en) * | 1998-06-30 | 2004-12-23 | Snutch Terrance P. | Calcium channel blockers comprising two benzhydril moieties |
US20040266784A1 (en) * | 1998-06-30 | 2004-12-30 | Snutch Terrance P. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
US6387897B1 (en) | 1998-06-30 | 2002-05-14 | Neuromed Technologies, Inc. | Preferentially substituted calcium channel blockers |
US6951862B2 (en) * | 1998-06-30 | 2005-10-04 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
US6310059B1 (en) | 1998-06-30 | 2001-10-30 | Neuromed Technologies, Inc. | Fused ring calcium channel blockers |
US6011035A (en) * | 1998-06-30 | 2000-01-04 | Neuromed Technologies Inc. | Calcium channel blockers |
US6943168B2 (en) * | 1998-06-30 | 2005-09-13 | Neuromed Technologies Inc. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
CA2397681C (en) | 1999-12-20 | 2011-03-15 | Neuromed Technologies, Inc. | Partially saturated calcium channel blockers |
DE10041574A1 (de) * | 2000-08-24 | 2002-03-07 | Merck Patent Gmbh | Chromenonderivate |
AU779232B2 (en) * | 2001-06-28 | 2005-01-13 | Activus Pharma Co., Ltd | Benzopyran derivative and antiallergic agent |
US20030199523A1 (en) * | 2002-02-28 | 2003-10-23 | Snutch Terrance P. | Heterocyclic calcium in channel blockers |
PT1514542E (pt) | 2002-06-14 | 2012-03-27 | Toyama Chemical Co Ltd | Composição medicamentosa incluindo tacrina ou donepezilo para melhorar as funções cerebrais |
WO2004017922A2 (en) * | 2002-08-23 | 2004-03-04 | University Of Connecticut | Keto cannabinoids with therapeutic indications |
JP2006526000A (ja) * | 2003-05-30 | 2006-11-16 | ニューロームド テクノロジーズ、インク. | N型カルシウムチャネル遮断薬としての3−アミノメチル−ピロリジン |
HRP20030604A2 (en) * | 2003-07-25 | 2005-04-30 | Pliva-Istra�iva�ki institut d.o.o. | Substituted furochromenes, preparation thereof andtheir antiinflammatory action |
HRP20030603A2 (en) * | 2003-07-25 | 2005-10-31 | Pliva-Istra�iva�ki institut d.o.o. | Substituted furochromene compounds of antiinflammatory action |
US7507760B2 (en) * | 2004-01-22 | 2009-03-24 | Neuromed Pharmaceuticals Ltd. | N-type calcium channel blockers |
US20050227999A1 (en) * | 2004-04-09 | 2005-10-13 | Neuromed Technologies Inc. | Diarylamine derivatives as calcium channel blockers |
DE102004063910B4 (de) * | 2004-07-05 | 2006-12-28 | Bioplanta Arzneimittel Gmbh | Trisubstituierte Benzopyranone sowie diese enthaltende Pflanzenextrakte und Mittel |
AU2005279600A1 (en) * | 2004-08-30 | 2006-03-09 | Neuromed Pharmaceuticals Ltd. | Urea derivatives as calcium channel blockers |
US7511077B2 (en) * | 2005-02-09 | 2009-03-31 | Neuromed Pharmaceuticals Ltd. | Diamine calcium channel blockers |
WO2007071035A1 (en) * | 2005-12-19 | 2007-06-28 | Neuromed Pharmaceuticals Ltd. | Heterocyclic amide derivatives as calcium channel blockers |
WO2007118323A1 (en) * | 2006-04-17 | 2007-10-25 | Neuromed Pharmaceuticals Ltd. | Isoxazole derivatives as calcium channel blockers |
US8362021B2 (en) * | 2006-05-11 | 2013-01-29 | Zalicus Pharmaceuticals Ltd. | Method for increasing the bioavailability of benzhydryl piperazine containing compounds |
WO2007137417A1 (en) * | 2006-05-26 | 2007-12-06 | Neuromed Pharmaceuticals Ltd. | Heterocyclic compounds as calcium channel blockers |
EP2061780A4 (en) * | 2006-09-14 | 2010-12-22 | Zalicus Pharmaceuticals Ltd | DIARYLE PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS |
WO2008043183A1 (en) * | 2006-10-13 | 2008-04-17 | Neuromed Pharmaceuticals Ltd. | Cyclopropyl-piperazine compounds as calcium channel blockers |
US8409560B2 (en) | 2011-03-08 | 2013-04-02 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
CN103491964A (zh) | 2011-03-08 | 2014-01-01 | 扎里卡斯药品有限公司 | 固体分散体制剂及其使用方法 |
CN102267971B (zh) | 2011-08-03 | 2013-03-27 | 华中科技大学 | 脂环并[c]苯并吡喃酮衍生物及其应用 |
CA3068254A1 (en) | 2017-06-20 | 2018-12-27 | Imbria Pharmaceuticals, Inc. | Compositions and methods for increasing efficiency of cardiac metabolism |
RU2705810C1 (ru) * | 2018-12-28 | 2019-11-12 | Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") | Противосудорожное средство |
US11530184B2 (en) | 2020-06-30 | 2022-12-20 | Imbria Pharmaceuticals, Inc. | Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
US11780811B2 (en) | 2020-06-30 | 2023-10-10 | Imbria Pharmaceuticals, Inc. | Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
US11883396B2 (en) | 2021-05-03 | 2024-01-30 | Imbria Pharmaceuticals, Inc. | Methods of treating kidney conditions using modified forms of trimetazidine |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE884459Q (fr) * | 1971-05-14 | 1981-01-26 | Boehringer Mannheim Gmbh | Derives de la 4-(omega-(coumarine-7-yl-oxy)-alkyl)-piperazine et procede de preparation |
DE3025385A1 (de) * | 1980-07-04 | 1982-01-28 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue tricyclische arylether, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
US4569994A (en) * | 1983-09-19 | 1986-02-11 | Pennwalt Corporation | Dibenzo[b,d]pyranyloxyaminopropanols |
US4558130A (en) * | 1984-03-27 | 1985-12-10 | Miles Laboratories, Inc. | Fluorogenic dihydroquinolone and dihydrocoumarin indicators for hydrogen peroxide |
DE3427985A1 (de) * | 1984-07-28 | 1986-01-30 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue 2h-l-benzopyran-2-on-derivate, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
DE3432239A1 (de) * | 1984-09-01 | 1986-03-13 | Standard Elektrik Lorenz Ag, 7000 Stuttgart | Optischer multiplexer/demultiplexer |
US4701456A (en) * | 1984-09-19 | 1987-10-20 | Warner-Lambert Company | Aminoalkoxybenzopyranones as antipsychotic and anxiolytic agents |
GB2168696B (en) * | 1984-12-21 | 1989-01-11 | Boehringer Biochemia Srl | Fluoro coumarins as antilymphoedema agents |
IN163948B (es) * | 1986-01-17 | 1988-12-10 | Robins Co Inc A H | |
AU629535B2 (en) * | 1988-02-10 | 1992-10-08 | A.H. Robins Company, Incorporated | N-substituted-arylalkyl and arylalkylene aminoheterocyclics as cardiovascular antihistaminic and antisecretory agents |
JP2974327B2 (ja) * | 1989-07-03 | 1999-11-10 | 三井化学株式会社 | ポリアルキル―2―アルコキシ―7―ヒドロキシクロマンの製造方法 |
US5248784A (en) * | 1989-12-28 | 1993-09-28 | Mitsui Toatsu Chemicals, Inc. | 4-carbonyl-substituted coumarin compound |
-
1991
- 1991-04-11 DE DE4111861A patent/DE4111861A1/de not_active Withdrawn
-
1992
- 1992-04-02 DE DE59207907T patent/DE59207907D1/de not_active Expired - Fee Related
- 1992-04-02 EP EP92908141A patent/EP0584091B1/de not_active Expired - Lifetime
- 1992-04-02 WO PCT/EP1992/000739 patent/WO1992018493A1/de active IP Right Grant
- 1992-04-02 AU AU15403/92A patent/AU658619B2/en not_active Ceased
- 1992-04-02 JP JP50763392A patent/JP3234221B2/ja not_active Expired - Fee Related
- 1992-04-02 US US08/133,017 patent/US5428038A/en not_active Expired - Fee Related
- 1992-04-02 AT AT92908141T patent/ATE147736T1/de not_active IP Right Cessation
- 1992-04-02 CA CA002108174A patent/CA2108174A1/en not_active Abandoned
- 1992-04-02 ES ES92908141T patent/ES2097908T3/es not_active Expired - Lifetime
- 1992-04-07 MX MX9201598A patent/MX9201598A/es unknown
- 1992-04-10 ZA ZA922614A patent/ZA922614B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE4111861A1 (de) | 1992-10-15 |
ES2097908T3 (es) | 1997-04-16 |
AU658619B2 (en) | 1995-04-27 |
WO1992018493A1 (de) | 1992-10-29 |
EP0584091A1 (de) | 1994-03-02 |
EP0584091B1 (de) | 1997-01-15 |
ZA922614B (en) | 1992-12-30 |
JP3234221B2 (ja) | 2001-12-04 |
JPH06506922A (ja) | 1994-08-04 |
US5428038A (en) | 1995-06-27 |
ATE147736T1 (de) | 1997-02-15 |
AU1540392A (en) | 1992-11-17 |
CA2108174A1 (en) | 1992-10-12 |
DE59207907D1 (de) | 1997-02-27 |
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