SE7503366L - Nya peptider. - Google Patents

Nya peptider.

Info

Publication number
SE7503366L
SE7503366L SE7503366A SE7503366A SE7503366L SE 7503366 L SE7503366 L SE 7503366L SE 7503366 A SE7503366 A SE 7503366A SE 7503366 A SE7503366 A SE 7503366A SE 7503366 L SE7503366 L SE 7503366L
Authority
SE
Sweden
Prior art keywords
peptider
new
tripeptides
disclosed
activity
Prior art date
Application number
SE7503366A
Other languages
English (en)
Other versions
SE425659B (sv
Inventor
D F Veber
F W Holly
F E Nutt
S L Varga
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE7503366L publication Critical patent/SE7503366L/sv
Publication of SE425659B publication Critical patent/SE425659B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SE7503366A 1974-04-03 1975-03-24 Forfarande for framstellning av tripeptider med antidpressiva och tyroidhormonfrigoringsstimulerande egenskaper SE425659B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45768974A 1974-04-03 1974-04-03
US05/543,734 US3959248A (en) 1974-04-03 1975-01-27 Analogs of thyrotropin-releasing hormone

Publications (2)

Publication Number Publication Date
SE7503366L true SE7503366L (sv) 1975-10-04
SE425659B SE425659B (sv) 1982-10-25

Family

ID=27038702

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7503366A SE425659B (sv) 1974-04-03 1975-03-24 Forfarande for framstellning av tripeptider med antidpressiva och tyroidhormonfrigoringsstimulerande egenskaper

Country Status (12)

Country Link
US (1) US3959248A (sv)
JP (2) JPS547793B2 (sv)
CH (2) CH617667A5 (sv)
CY (1) CY1071A (sv)
DE (1) DE2514381C3 (sv)
ES (1) ES436027A1 (sv)
FR (1) FR2266515B1 (sv)
GB (1) GB1473480A (sv)
HK (1) HK43480A (sv)
KE (1) KE3067A (sv)
NL (1) NL171700C (sv)
SE (1) SE425659B (sv)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2449167C2 (de) * 1974-10-16 1984-05-24 Grünenthal GmbH, 5190 Stolberg N-Acyl-L-histidyl-L-prolinamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
GB1523598A (en) * 1975-03-08 1978-09-06 Reckitt & Colmann Prod Ltd Tripeptides
JPS5944308B2 (ja) * 1976-03-23 1984-10-29 武田薬品工業株式会社 ペプタイド
JPS5920647B2 (ja) * 1976-10-01 1984-05-15 武田薬品工業株式会社 注射剤
US4161600A (en) * 1976-12-22 1979-07-17 Merck & Co., Inc. Dextro and levo-6-oxo-2-piperidinecarboxylic acid quinine salts
US4066749A (en) * 1977-01-24 1978-01-03 Merck & Co., Inc. Tetrapeptide analog of TRH
AU4125578A (en) * 1977-11-09 1979-05-17 Merck & Co Inc Tripeptides
US4215110A (en) * 1978-09-22 1980-07-29 Merck & Co., Inc. Method of treating hypertension
DE2905502C2 (de) * 1979-02-14 1982-07-15 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von LH-RH bzw. LH-RH-Analoga und Pyroglutamyl-N↑i↑m↑-dinitrophenyl-histidin
HU180925B (en) * 1979-06-28 1983-05-30 Richter Gedeon Vegyeszet Process for producing tripeptide-amides trh-analogues,effectives on the central nerve systhem
HU180926B (en) * 1979-06-28 1983-05-30 Richter Gedeon Vegyeszet Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem
US4254261A (en) * 1979-10-15 1981-03-03 Merck & Co., Inc. Dehydroabietylammonium salts of 6-oxo-2-piperidinecarboxylic acid
US4328134A (en) * 1980-05-06 1982-05-04 Schally Andrew Victor Anorexigenic peptides
US4426378A (en) 1981-04-09 1984-01-17 The United States Of America As Represented By The Secretary Of The Army Thyrotropin releasing hormone in therapy of shock and as a central nervous system stimulant
HU184481B (en) * 1981-10-02 1984-08-28 Richter Gedeon Vegyeszet Process for producing tripeptides for diminishing appetite
JPS59155346A (ja) * 1983-02-24 1984-09-04 Itsuro Sofue ペプタイド
CA1256650A (en) * 1983-03-25 1989-06-27 Toshinari Tamura Process of producing 2-azetidinone-4-substituted compounds, and medicaments containing the compounds
US4608365A (en) * 1984-03-30 1986-08-26 University Of Southern California Treatment of neurologic functions
IT1202426B (it) * 1987-01-26 1989-02-09 Poli Ind Chimica Spa Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono
US5686420A (en) * 1987-06-05 1997-11-11 Georgetown University Thyrotropin-releasing hormone analogs and method of use
US5151497A (en) * 1989-02-21 1992-09-29 Japan Tobacco Inc. Histidyl peptide derivatives
AT392949B (de) * 1989-03-17 1991-07-10 Gfm Holding Ag Vorrichtung zum abnehmen eines flaechigen werkstueckes von einer anklebenden unterfolie
DK437289D0 (da) * 1989-09-04 1989-09-04 Hans Bundgaard Prodrug derivatives of thyrotropin-releasing hormone (trh)
HU206374B (en) * 1990-09-03 1992-10-28 Richter Gedeon Vegyeszet Process for producing pentapeptide and its salts specifically inhibiting proliferation of epidermic cells, as well as pharmaceutical compositions comprising same as active ingredient
GB0125446D0 (en) * 2001-10-23 2001-12-12 Ferring Bv Novel anti-diabetic agents
AU2003228610A1 (en) * 2002-04-19 2003-11-03 University Of Florida Thyrotropin-releasing hormone analogues and their therapeutic applications
US7462595B2 (en) * 2004-09-17 2008-12-09 Prange Jr Arthur Jergen Methods for treating cancer-related fatigue

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5714337B2 (sv) * 1973-02-23 1982-03-24

Also Published As

Publication number Publication date
ES436027A1 (es) 1977-05-01
HK43480A (en) 1980-08-22
DE2514381A1 (de) 1975-10-09
KE3067A (en) 1980-08-08
FR2266515A1 (sv) 1975-10-31
NL171700C (nl) 1983-05-02
DE2514381B2 (de) 1980-04-17
NL7503023A (nl) 1975-10-07
GB1473480A (en) 1977-05-11
CH620196A5 (sv) 1980-11-14
SE425659B (sv) 1982-10-25
NL171700B (nl) 1982-12-01
JPS5492957A (en) 1979-07-23
JPS50154247A (sv) 1975-12-12
JPS547793B2 (sv) 1979-04-10
CH617667A5 (sv) 1980-06-13
CY1071A (en) 1980-10-24
DE2514381C3 (de) 1980-12-11
US3959248A (en) 1976-05-25
AU7921575A (en) 1976-09-23
FR2266515B1 (sv) 1978-07-28

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