SE526106C2 - Linjär blockpolymer samt fiber, film, poröst material och implantat innefattande polymeren - Google Patents
Linjär blockpolymer samt fiber, film, poröst material och implantat innefattande polymerenInfo
- Publication number
- SE526106C2 SE526106C2 SE0201948A SE0201948A SE526106C2 SE 526106 C2 SE526106 C2 SE 526106C2 SE 0201948 A SE0201948 A SE 0201948A SE 0201948 A SE0201948 A SE 0201948A SE 526106 C2 SE526106 C2 SE 526106C2
- Authority
- SE
- Sweden
- Prior art keywords
- derived
- linear block
- block polymer
- fiber
- polymer
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title claims abstract description 30
- 239000007943 implant Substances 0.000 title claims description 16
- 239000000835 fiber Substances 0.000 title claims description 10
- 239000010408 film Substances 0.000 title 1
- 239000011148 porous material Substances 0.000 title 1
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 claims abstract description 6
- JQVDAXLFBXTEQA-UHFFFAOYSA-N dibutylamine Chemical compound CCCCNCCCC JQVDAXLFBXTEQA-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000000178 monomer Substances 0.000 claims abstract description 6
- AOHJOMMDDJHIJH-UHFFFAOYSA-N propylenediamine Chemical compound CC(N)CN AOHJOMMDDJHIJH-UHFFFAOYSA-N 0.000 claims abstract description 6
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 claims abstract description 5
- 150000004985 diamines Chemical class 0.000 claims abstract 2
- 239000000463 material Substances 0.000 claims description 15
- VHRGRCVQAFMJIZ-UHFFFAOYSA-N cadaverine Chemical compound NCCCCCN VHRGRCVQAFMJIZ-UHFFFAOYSA-N 0.000 claims description 6
- 229920001610 polycaprolactone Polymers 0.000 claims description 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 4
- 150000002009 diols Chemical class 0.000 claims description 4
- UPMLOUAZCHDJJD-UHFFFAOYSA-N 4,4'-Diphenylmethane Diisocyanate Chemical compound C1=CC(N=C=O)=CC=C1CC1=CC=C(N=C=O)C=C1 UPMLOUAZCHDJJD-UHFFFAOYSA-N 0.000 claims description 3
- -1 ester diol Chemical class 0.000 claims description 3
- 239000004632 polycaprolactone Substances 0.000 claims description 3
- 241001465754 Metazoa Species 0.000 claims description 2
- 239000005700 Putrescine Substances 0.000 claims description 2
- WNLRTRBMVRJNCN-UHFFFAOYSA-L adipate(2-) Chemical compound [O-]C(=O)CCCCC([O-])=O WNLRTRBMVRJNCN-UHFFFAOYSA-L 0.000 claims description 2
- 125000005442 diisocyanate group Chemical group 0.000 claims description 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 2
- NAQMVNRVTILPCV-UHFFFAOYSA-N hexane-1,6-diamine Chemical compound NCCCCCCN NAQMVNRVTILPCV-UHFFFAOYSA-N 0.000 claims description 2
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 claims description 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 2
- 238000002513 implantation Methods 0.000 claims description 2
- UWJJYHHHVWZFEP-UHFFFAOYSA-N pentane-1,1-diol Chemical compound CCCCC(O)O UWJJYHHHVWZFEP-UHFFFAOYSA-N 0.000 claims description 2
- WLJVNTCWHIRURA-UHFFFAOYSA-N pimelic acid Chemical compound OC(=O)CCCCCC(O)=O WLJVNTCWHIRURA-UHFFFAOYSA-N 0.000 claims description 2
- ZNZJJSYHZBXQSM-UHFFFAOYSA-N propane-2,2-diamine Chemical compound CC(C)(N)N ZNZJJSYHZBXQSM-UHFFFAOYSA-N 0.000 claims 1
- XFNJVJPLKCPIBV-UHFFFAOYSA-N trimethylenediamine Chemical compound NCCCN XFNJVJPLKCPIBV-UHFFFAOYSA-N 0.000 abstract description 12
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 69
- KWGKDLIKAYFUFQ-UHFFFAOYSA-M lithium chloride Chemical compound [Li+].[Cl-] KWGKDLIKAYFUFQ-UHFFFAOYSA-M 0.000 description 14
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 9
- 230000015556 catabolic process Effects 0.000 description 9
- 238000006731 degradation reaction Methods 0.000 description 9
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 6
- 239000002552 dosage form Substances 0.000 description 4
- 229910052757 nitrogen Inorganic materials 0.000 description 4
- 239000003643 water by type Substances 0.000 description 3
- 229920002334 Spandex Polymers 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- GHWVXCQZPNWFRO-UHFFFAOYSA-N butane-2,3-diamine Chemical compound CC(N)C(C)N GHWVXCQZPNWFRO-UHFFFAOYSA-N 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- KIDHWZJUCRJVML-UHFFFAOYSA-N putrescine Chemical compound NCCCCN KIDHWZJUCRJVML-UHFFFAOYSA-N 0.000 description 2
- 230000008929 regeneration Effects 0.000 description 2
- 238000011069 regeneration method Methods 0.000 description 2
- 238000001542 size-exclusion chromatography Methods 0.000 description 2
- 239000004759 spandex Substances 0.000 description 2
- 238000009987 spinning Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 239000012948 isocyanate Substances 0.000 description 1
- 150000002513 isocyanates Chemical class 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 210000003041 ligament Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- VXYRWKSIAWIQMG-UHFFFAOYSA-K manganese(2+) N-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate triphenylstannyl acetate Chemical compound [Mn++].[S-]C(=S)NCCNC([S-])=S.CC(=O)O[Sn](c1ccccc1)(c1ccccc1)c1ccccc1 VXYRWKSIAWIQMG-UHFFFAOYSA-K 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920006306 polyurethane fiber Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N urethane group Chemical group NC(=O)OCC JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- 238000002166 wet spinning Methods 0.000 description 1
Classifications
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
- D01F6/58—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products
- D01F6/70—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/08—Processes
- C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
- C08G18/4266—Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
- C08G18/4269—Lactones
- C08G18/4277—Caprolactone and/or substituted caprolactone
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Textile Engineering (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Polyurethanes Or Polyureas (AREA)
- Artificial Filaments (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Ceramic Products (AREA)
- Graft Or Block Polymers (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0201948A SE526106C2 (sv) | 2002-06-20 | 2002-06-20 | Linjär blockpolymer samt fiber, film, poröst material och implantat innefattande polymeren |
| EP03733793A EP1516003B1 (en) | 2002-06-20 | 2003-06-23 | Linear block polymer |
| DE60313169T DE60313169T2 (de) | 2002-06-20 | 2003-06-23 | Lineares Bock-Polymer |
| ES03733793T ES2285130T3 (es) | 2002-06-20 | 2003-06-23 | Polimero lineal de bloques. |
| CNB038167190A CN1289563C (zh) | 2002-06-20 | 2003-06-23 | 线性嵌段聚合物 |
| JP2004515332A JP4287370B2 (ja) | 2002-06-20 | 2003-06-23 | 線状ブロック重合体 |
| PCT/SE2003/001085 WO2004000904A1 (en) | 2002-06-20 | 2003-06-23 | Linear block polymer |
| US10/518,428 US20060063909A1 (en) | 2002-06-20 | 2003-06-23 | Linear blocker polymer |
| AT03733793T ATE359308T1 (de) | 2002-06-20 | 2003-06-23 | Lineares blockpolymer |
| AU2003239077A AU2003239077B2 (en) | 2002-06-20 | 2003-06-23 | Linear block polymer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0201948A SE526106C2 (sv) | 2002-06-20 | 2002-06-20 | Linjär blockpolymer samt fiber, film, poröst material och implantat innefattande polymeren |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE0201948D0 SE0201948D0 (sv) | 2002-06-20 |
| SE0201948L SE0201948L (sv) | 2003-12-21 |
| SE526106C2 true SE526106C2 (sv) | 2005-07-05 |
Family
ID=20288306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0201948A SE526106C2 (sv) | 2002-06-20 | 2002-06-20 | Linjär blockpolymer samt fiber, film, poröst material och implantat innefattande polymeren |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20060063909A1 (enExample) |
| EP (1) | EP1516003B1 (enExample) |
| JP (1) | JP4287370B2 (enExample) |
| CN (1) | CN1289563C (enExample) |
| AT (1) | ATE359308T1 (enExample) |
| AU (1) | AU2003239077B2 (enExample) |
| DE (1) | DE60313169T2 (enExample) |
| ES (1) | ES2285130T3 (enExample) |
| SE (1) | SE526106C2 (enExample) |
| WO (1) | WO2004000904A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9566370B2 (en) | 2004-12-23 | 2017-02-14 | Novus Scientific Ab | Mesh implant for use in reconstruction of soft tissue defects |
| US9717825B2 (en) * | 2004-12-23 | 2017-08-01 | Novus Scientific Ab | Mesh implant for use in reconstruction of soft tissue defects |
| US8083755B2 (en) | 2006-06-22 | 2011-12-27 | Novus Scientific Pte. Ltd. | Mesh implant for use in reconstruction of soft tissue defects |
| JP5366068B2 (ja) * | 2008-02-29 | 2013-12-11 | 独立行政法人産業技術総合研究所 | 柔軟性に富む生分解性材料とその製造方法 |
| WO2014004334A1 (en) * | 2012-06-25 | 2014-01-03 | Lubrizol Advanced Materials, Inc. | Process for making biodegradable and/or bioabsorbable polymers |
| CN109851744B (zh) * | 2018-12-21 | 2021-02-05 | 苏州为尔康生物科技有限公司 | 一种可降解聚氨酯生物材料及其制备方法和应用 |
| CN117224289B (zh) * | 2023-11-14 | 2024-02-20 | 北京爱康宜诚医疗器材有限公司 | 一种非对称膝关节假体及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US621441A (en) * | 1899-03-21 | behrend | ||
| SE505703C2 (sv) * | 1995-12-15 | 1997-09-29 | Polyrand Ab | Linjär blockpolymer innefattande urea- och uretangrupper, förfarande för framställning av linjära blockpolymerer samt användning av blockpolymererna som implantat |
| US6221997B1 (en) * | 1997-04-28 | 2001-04-24 | Kimberly Ann Woodhouse | Biodegradable polyurethanes |
| DE19841512A1 (de) * | 1998-06-02 | 1999-12-09 | Bayer Ag | Elastanfasern aus aliphatischen Diisocyanaten |
| DE69912956T2 (de) * | 1998-06-05 | 2004-11-11 | Polyganics B.V. | Biomedizinisches polyurethan, seine herstellung und verwendung |
| SE514064C2 (sv) * | 1999-02-02 | 2000-12-18 | Artimplant Dev Artdev Ab | Film för medicinsk användning bestående av linjära blockpolymerer av polyuretaner samt förfarande för framställning av en sådan film |
-
2002
- 2002-06-20 SE SE0201948A patent/SE526106C2/sv not_active IP Right Cessation
-
2003
- 2003-06-23 AU AU2003239077A patent/AU2003239077B2/en not_active Ceased
- 2003-06-23 EP EP03733793A patent/EP1516003B1/en not_active Expired - Lifetime
- 2003-06-23 ES ES03733793T patent/ES2285130T3/es not_active Expired - Lifetime
- 2003-06-23 AT AT03733793T patent/ATE359308T1/de not_active IP Right Cessation
- 2003-06-23 CN CNB038167190A patent/CN1289563C/zh not_active Expired - Fee Related
- 2003-06-23 DE DE60313169T patent/DE60313169T2/de not_active Expired - Lifetime
- 2003-06-23 WO PCT/SE2003/001085 patent/WO2004000904A1/en not_active Ceased
- 2003-06-23 JP JP2004515332A patent/JP4287370B2/ja not_active Expired - Fee Related
- 2003-06-23 US US10/518,428 patent/US20060063909A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1516003B1 (en) | 2007-04-11 |
| JP4287370B2 (ja) | 2009-07-01 |
| AU2003239077B2 (en) | 2009-09-10 |
| ATE359308T1 (de) | 2007-05-15 |
| JP2005535739A (ja) | 2005-11-24 |
| DE60313169T2 (de) | 2007-12-20 |
| CN1289563C (zh) | 2006-12-13 |
| US20060063909A1 (en) | 2006-03-23 |
| EP1516003A1 (en) | 2005-03-23 |
| CN1668663A (zh) | 2005-09-14 |
| ES2285130T3 (es) | 2007-11-16 |
| SE0201948D0 (sv) | 2002-06-20 |
| AU2003239077A1 (en) | 2004-01-06 |
| DE60313169D1 (en) | 2007-05-24 |
| SE0201948L (sv) | 2003-12-21 |
| WO2004000904A1 (en) | 2003-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |