SE517006C2 - Farmaceutisk komposition med förbättrad analgetisk aktivitet innehållande (S)-2-(6-metoxi-2-naftyl)propionsyra (naproxen) och arginin - Google Patents

Farmaceutisk komposition med förbättrad analgetisk aktivitet innehållande (S)-2-(6-metoxi-2-naftyl)propionsyra (naproxen) och arginin

Info

Publication number
SE517006C2
SE517006C2 SE9401005A SE9401005A SE517006C2 SE 517006 C2 SE517006 C2 SE 517006C2 SE 9401005 A SE9401005 A SE 9401005A SE 9401005 A SE9401005 A SE 9401005A SE 517006 C2 SE517006 C2 SE 517006C2
Authority
SE
Sweden
Prior art keywords
naproxen
arginine
pharmaceutical composition
sodium
pharmaceutical
Prior art date
Application number
SE9401005A
Other languages
English (en)
Swedish (sv)
Other versions
SE9401005L (sv
SE9401005D0 (sv
Inventor
Federico Stroppolo
Daniele Bonadeo
Luigi Vigano
Annibale Gazzaniga
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of SE9401005D0 publication Critical patent/SE9401005D0/xx
Publication of SE9401005L publication Critical patent/SE9401005L/xx
Publication of SE517006C2 publication Critical patent/SE517006C2/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE9401005A 1993-03-26 1994-03-25 Farmaceutisk komposition med förbättrad analgetisk aktivitet innehållande (S)-2-(6-metoxi-2-naftyl)propionsyra (naproxen) och arginin SE517006C2 (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI930582A IT1272149B (it) 1993-03-26 1993-03-26 Composizione farmeceutiche ad attivita' analgesica

Publications (3)

Publication Number Publication Date
SE9401005D0 SE9401005D0 (sv) 1994-03-25
SE9401005L SE9401005L (sv) 1994-09-27
SE517006C2 true SE517006C2 (sv) 2002-04-02

Family

ID=11365508

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9401005A SE517006C2 (sv) 1993-03-26 1994-03-25 Farmaceutisk komposition med förbättrad analgetisk aktivitet innehållande (S)-2-(6-metoxi-2-naftyl)propionsyra (naproxen) och arginin

Country Status (12)

Country Link
US (1) US5693312A (es)
JP (1) JP3784843B2 (es)
BE (1) BE1006718A3 (es)
CA (1) CA2120048C (es)
CH (1) CH686403A5 (es)
DE (1) DE4410470A1 (es)
ES (1) ES2109131B1 (es)
FR (1) FR2703249B1 (es)
GB (1) GB2276545B (es)
IT (1) IT1272149B (es)
NL (1) NL194390C (es)
SE (1) SE517006C2 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
GB9924636D0 (en) * 1999-10-18 1999-12-22 Norgine Bv Laxative preparation
US20030235629A1 (en) * 1999-11-06 2003-12-25 Janmarie Hornack Dietary supplement containing alkaline electrolyte buffers
JP5185488B2 (ja) * 2001-11-02 2013-04-17 カンバーランド ファーマシューティカルズ，インコーポレーテッド ２−（４−イソブチルフェニル）プロピオン酸の医薬組成物
US6727286B2 (en) 2001-11-02 2004-04-27 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
CA2521902A1 (en) * 2003-04-11 2004-10-21 Pfizer Inc. Pharmaceutical combination comprising eletriptan and sodium bicarbonate
US20050008699A1 (en) * 2003-07-11 2005-01-13 Fred Wehling Effervescent glucosamine composition
PE20050445A1 (es) * 2003-10-30 2005-06-18 Bayer Consumer Care Ag Forma de presentacion del naproxeno sodico
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
EP1905427B1 (en) 2006-09-28 2010-11-24 Losan Pharma GmbH Rapidly solubilising formulation of non-steroidal anti-inflammatory drugs
US20080292731A1 (en) * 2007-05-22 2008-11-27 Glenn Abrahmsohn Method for pain control
US8828452B2 (en) * 2007-05-22 2014-09-09 Glenn Abrahmsohn Method for pain control
BRPI0800951A2 (pt) * 2008-04-09 2012-02-22 Ems Sa novos compostos derivados de taurina e seus usos, processo de sua preparação e composições farmacêuticas contendo os mesmos
JP7163015B2 (ja) * 2016-10-31 2022-10-31 エスエス製薬株式会社 経口固形組成物
JP7163014B2 (ja) * 2016-10-31 2022-10-31 エスエス製薬株式会社 感冒薬
US11779541B2 (en) * 2019-03-26 2023-10-10 Johnson & Johnson Consumer Inc. Immediate release dosage form

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
US4344929A (en) * 1980-04-25 1982-08-17 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4587249A (en) * 1982-07-22 1986-05-06 Analgesic Associates Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
US5053396A (en) * 1985-08-27 1991-10-01 Blass David H Therapeutic composition
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
IT1197038B (it) * 1986-08-01 1988-11-25 Zambon Spa Composizione farmaceutica ad attivita' analgesica
SE463541B (sv) * 1987-08-31 1990-12-10 Lejus Medical Ab Granulaer produkt oeverdragen av en smaelta av sig sjaelv samt foerfarande foer dess framstaellning
GB8724763D0 (en) * 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations
GB8813682D0 (en) * 1988-06-09 1988-07-13 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
ZA903759B (en) * 1989-05-16 1991-02-27 Puetter Medice Chem Pharm Process for preparing optically active 2-aryl alkanoic acids,in particular 2-aryl propionic acids
US5262179A (en) * 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
HUT59656A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing s/+/-phenyl-alkanoic acids and alpha-amino-acids containing complexes and pharmaceutical compositions containing them as active components
HUT59692A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing complexes containing s/+/-phenyl-alkanoic acids and aminosugars

Also Published As

Publication number Publication date
US5693312A (en) 1997-12-02
ITMI930582A1 (it) 1994-09-26
NL194390B (nl) 2001-11-01
GB9405420D0 (en) 1994-05-04
JP3784843B2 (ja) 2006-06-14
FR2703249B1 (fr) 1995-07-13
BE1006718A3 (fr) 1994-11-22
NL194390C (nl) 2002-03-04
FR2703249A1 (fr) 1994-10-07
CA2120048C (en) 2004-01-27
NL9400481A (nl) 1994-10-17
GB2276545B (en) 1996-08-14
SE9401005L (sv) 1994-09-27
JPH06321777A (ja) 1994-11-22
DE4410470A1 (de) 1994-09-29
GB2276545A (en) 1994-10-05
IT1272149B (it) 1997-06-11
CA2120048A1 (en) 1994-09-27
ES2109131A1 (es) 1998-01-01
ES2109131B1 (es) 1998-08-16
ITMI930582A0 (it) 1993-03-26
CH686403A5 (it) 1996-03-29
SE9401005D0 (sv) 1994-03-25

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