SE463349B - Farmaceutiskt preparat foer profylax mot och/eller behandling av beta-streptokockinducerad tonsillit - Google Patents
Farmaceutiskt preparat foer profylax mot och/eller behandling av beta-streptokockinducerad tonsillitInfo
- Publication number
- SE463349B SE463349B SE8900510A SE8900510A SE463349B SE 463349 B SE463349 B SE 463349B SE 8900510 A SE8900510 A SE 8900510A SE 8900510 A SE8900510 A SE 8900510A SE 463349 B SE463349 B SE 463349B
- Authority
- SE
- Sweden
- Prior art keywords
- strains
- ncib
- streptococcal
- streptococci
- treatment
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title claims description 15
- 239000000825 pharmaceutical preparation Substances 0.000 title claims description 4
- 206010044008 tonsillitis Diseases 0.000 claims description 19
- 244000005700 microbiome Species 0.000 claims description 14
- 241000194023 Streptococcus sanguinis Species 0.000 claims description 7
- 238000011321 prophylaxis Methods 0.000 claims description 7
- 239000008194 pharmaceutical composition Substances 0.000 claims description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 5
- 241001134658 Streptococcus mitis Species 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 230000035899 viability Effects 0.000 claims description 4
- 229930182555 Penicillin Natural products 0.000 claims description 3
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims description 3
- 229940049954 penicillin Drugs 0.000 claims description 3
- 239000011780 sodium chloride Substances 0.000 claims description 3
- 235000020183 skimmed milk Nutrition 0.000 claims description 2
- 239000007921 spray Substances 0.000 claims description 2
- 230000008021 deposition Effects 0.000 claims 1
- 241001505901 Streptococcus sp. 'group A' Species 0.000 description 22
- 230000002401 inhibitory effect Effects 0.000 description 14
- 238000002360 preparation method Methods 0.000 description 11
- 208000015181 infectious disease Diseases 0.000 description 7
- 210000003800 pharynx Anatomy 0.000 description 7
- 230000020477 pH reduction Effects 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 230000001580 bacterial effect Effects 0.000 description 5
- 239000000969 carrier Substances 0.000 description 5
- 239000002609 medium Substances 0.000 description 5
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 238000002513 implantation Methods 0.000 description 4
- 108010062877 Bacteriocins Proteins 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000000813 microbial effect Effects 0.000 description 3
- 230000000306 recurrent effect Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 229920001817 Agar Polymers 0.000 description 2
- 101100298295 Drosophila melanogaster flfl gene Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 229930195708 Penicillin V Natural products 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 241000194017 Streptococcus Species 0.000 description 2
- 241001312524 Streptococcus viridans Species 0.000 description 2
- 206010044013 Tonsillitis streptococcal Diseases 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 239000008272 agar Substances 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 229960003276 erythromycin Drugs 0.000 description 2
- 230000002452 interceptive effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229940056367 penicillin v Drugs 0.000 description 2
- BPLBGHOLXOTWMN-MBNYWOFBSA-N phenoxymethylpenicillin Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)COC1=CC=CC=C1 BPLBGHOLXOTWMN-MBNYWOFBSA-N 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- DYFLEINNYRXWNC-UHFFFAOYSA-N 3-hydroxybutan-2-one;2-oxopropanoic acid Chemical compound CC(O)C(C)=O.CC(=O)C(O)=O DYFLEINNYRXWNC-UHFFFAOYSA-N 0.000 description 1
- PLXMOAALOJOTIY-FPTXNFDTSA-N Aesculin Natural products OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1Oc2cc3C=CC(=O)Oc3cc2O PLXMOAALOJOTIY-FPTXNFDTSA-N 0.000 description 1
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
- 241001279686 Allium moly Species 0.000 description 1
- 241000670727 Amida Species 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- 231100000699 Bacterial toxin Toxicity 0.000 description 1
- WNBCMONIPIJTSB-BGNCJLHMSA-N Cichoriin Natural products O([C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1)c1c(O)cc2c(OC(=O)C=C2)c1 WNBCMONIPIJTSB-BGNCJLHMSA-N 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 108090000204 Dipeptidase 1 Proteins 0.000 description 1
- 101100218662 Felis catus GLB1 gene Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 235000003332 Ilex aquifolium Nutrition 0.000 description 1
- 241000209027 Ilex aquifolium Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 208000035415 Reinfection Diseases 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 241000193996 Streptococcus pyogenes Species 0.000 description 1
- 206010066901 Treatment failure Diseases 0.000 description 1
- 241000394605 Viola striata Species 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000008186 active pharmaceutical agent Substances 0.000 description 1
- 206010001093 acute tonsillitis Diseases 0.000 description 1
- 230000003042 antagnostic effect Effects 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 239000000688 bacterial toxin Substances 0.000 description 1
- 102000006995 beta-Glucosidase Human genes 0.000 description 1
- 108010047754 beta-Glucosidase Proteins 0.000 description 1
- 102000006635 beta-lactamase Human genes 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 238000004061 bleaching Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000006161 blood agar Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000007382 columbia agar Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- XHCADAYNFIFUHF-TVKJYDDYSA-N esculin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C(=C1)O)=CC2=C1OC(=O)C=C2 XHCADAYNFIFUHF-TVKJYDDYSA-N 0.000 description 1
- 229940093496 esculin Drugs 0.000 description 1
- AWRMZKLXZLNBBK-UHFFFAOYSA-N esculin Natural products OC1OC(COc2cc3C=CC(=O)Oc3cc2O)C(O)C(O)C1O AWRMZKLXZLNBBK-UHFFFAOYSA-N 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229940097042 glucuronate Drugs 0.000 description 1
- 229940096919 glycogen Drugs 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 230000009036 growth inhibition Effects 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- YECBIJXISLIIDS-UHFFFAOYSA-N mepyramine Chemical compound C1=CC(OC)=CC=C1CN(CCN(C)C)C1=CC=CC=N1 YECBIJXISLIIDS-UHFFFAOYSA-N 0.000 description 1
- JVXXKQIRGQDWOJ-UHFFFAOYSA-N naphthalene-2-carboxamide Chemical compound C1=CC=CC2=CC(C(=O)N)=CC=C21 JVXXKQIRGQDWOJ-UHFFFAOYSA-N 0.000 description 1
- 210000001989 nasopharynx Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- RYVMUASDIZQXAA-UHFFFAOYSA-N pyranoside Natural products O1C2(OCC(C)C(OC3C(C(O)C(O)C(CO)O3)O)C2)C(C)C(C2(CCC3C4(C)CC5O)C)C1CC2C3CC=C4CC5OC(C(C1O)O)OC(CO)C1OC(C1OC2C(C(OC3C(C(O)C(O)C(CO)O3)O)C(O)C(CO)O2)O)OC(CO)C(O)C1OC1OCC(O)C(O)C1O RYVMUASDIZQXAA-UHFFFAOYSA-N 0.000 description 1
- 230000003362 replicative effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000004326 stimulated echo acquisition mode for imaging Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 239000007160 ty medium Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/885—Streptococcus
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Steroid Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (28)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8900510A SE463349B (sv) | 1989-02-15 | 1989-02-15 | Farmaceutiskt preparat foer profylax mot och/eller behandling av beta-streptokockinducerad tonsillit |
| ZA90692A ZA90692B (en) | 1989-02-15 | 1990-01-30 | A pharmaceutical preparation in the treatment of tonsillitis |
| IL9324290A IL93242A (en) | 1989-02-15 | 1990-02-01 | Pharmaceutical preparation for the treatment of beta-streptococcal tonsillitis comprising a streptococcus strain |
| NZ232381A NZ232381A (en) | 1989-02-15 | 1990-02-05 | Pharmaceutical preparation for the treatment of beta o streptococcal tonsillitis |
| YU23490A YU23490A (sh) | 1989-02-15 | 1990-02-07 | Farmaceutski preparat za lečenje tonzilitisa |
| PH40021A PH27203A (en) | 1989-02-15 | 1990-02-08 | A pharmaceutical preparation in the treatment of tonsilitis |
| IE900459A IE900459L (en) | 1989-02-15 | 1990-02-09 | A pharmaceutical preparation in the treatment of tonsillitis |
| AT90903444T ATE142503T1 (de) | 1989-02-15 | 1990-02-12 | Arzneimittelzubereitung bei der behandlung von tonsillitis |
| DK90903444.9T DK0458855T3 (da) | 1989-02-15 | 1990-02-12 | Farmaceutisk præparat til behandling af tonsillitis |
| PCT/SE1990/000089 WO1990009186A1 (en) | 1989-02-15 | 1990-02-12 | A pharmaceutical preparation in the treatment of tonsillitis |
| CA002047189A CA2047189A1 (en) | 1989-02-15 | 1990-02-12 | Pharmaceutical preparation in the treatment of tonsillitis |
| GR900100092A GR1000639B (el) | 1989-02-15 | 1990-02-12 | Μεθοδος για την παρασκευη μιας συνθεσεως για την αντιμετωπιση της αμυγδαλιτιδας. |
| AU51577/90A AU628493B2 (en) | 1989-02-15 | 1990-02-12 | A pharmaceutical preparation in the treatment of tonsillitis |
| EP90903444A EP0458855B1 (en) | 1989-02-15 | 1990-02-12 | A pharmaceutical preparation in the treatment of tonsillitis |
| HU901920A HU209915B (en) | 1989-02-15 | 1990-02-12 | Method for the preparation of pharmaceutical compositions in treatment of tonsillitis alpha-streptococcus strain |
| ES90903444T ES2091818T3 (es) | 1989-02-15 | 1990-02-12 | Preparado farmaceutico util en el tratamiento de la amigdalitis. |
| DE69028520T DE69028520T2 (de) | 1989-02-15 | 1990-02-12 | Arzneimittelzubereitung bei der behandlung von tonsillitis |
| EG7290A EG19075A (en) | 1989-02-15 | 1990-02-13 | A process for preparing a pharmaceutical preparation in the treatment of tonsillitis |
| PT93141A PT93141A (pt) | 1989-02-15 | 1990-02-14 | Processo para a preparacao de composicoes farmaceuticas contendo certas estirpes de estreptococos apropriadas para o tratamento de amigdalites |
| DD90337852A DD291926A5 (de) | 1989-02-15 | 1990-02-14 | Verfahren zur herstellung eines mittels gegen tonsillitis |
| IS3547A IS1678B (is) | 1989-02-15 | 1990-02-14 | Aðferð til framleiðslu á lyfjablöndu gegn hálskirtlabólgu |
| CS90748A CS74890A2 (en) | 1989-02-15 | 1990-02-15 | Pharmaceutical for tonsilitis prophylaxis and/ or therapy |
| AR90316173A AR247099A1 (es) | 1989-02-15 | 1990-02-15 | Un procedimiento para la obtencion de una preparacion farmaceutica util en la profilaxis y/o el tratamiento de tonsilitis beta-estreptococica. |
| MYPI90000256A MY106487A (en) | 1989-02-15 | 1990-02-15 | A pharmaceutical preparation in the treatment of tonsillitis |
| CN90101773A CN1046099A (zh) | 1989-02-15 | 1990-02-15 | 一种治疗扁桃体炎的药物制剂 |
| NO913162A NO178883C (no) | 1989-02-15 | 1991-08-13 | Fremgangsmåte for fremstilling av et farmasöytisk preparat for behandling av tonsillitt |
| FI913845A FI101452B1 (fi) | 1989-02-15 | 1991-08-14 | Menetelmä tonsilliitin ennalta ehkäisyyn ja/tai hoitoon tarkoitetun farmaseuttisen valmisteen valmistamiseksi |
| US08/194,753 US5378459A (en) | 1989-02-15 | 1994-02-10 | Pharmaceutical preparation in the treatment of tonsillitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8900510A SE463349B (sv) | 1989-02-15 | 1989-02-15 | Farmaceutiskt preparat foer profylax mot och/eller behandling av beta-streptokockinducerad tonsillit |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8900510D0 SE8900510D0 (sv) | 1989-02-15 |
| SE8900510L SE8900510L (sv) | 1990-08-16 |
| SE463349B true SE463349B (sv) | 1990-11-12 |
Family
ID=20375049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8900510A SE463349B (sv) | 1989-02-15 | 1989-02-15 | Farmaceutiskt preparat foer profylax mot och/eller behandling av beta-streptokockinducerad tonsillit |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5378459A (pt) |
| EP (1) | EP0458855B1 (pt) |
| CN (1) | CN1046099A (pt) |
| AR (1) | AR247099A1 (pt) |
| AT (1) | ATE142503T1 (pt) |
| AU (1) | AU628493B2 (pt) |
| CA (1) | CA2047189A1 (pt) |
| CS (1) | CS74890A2 (pt) |
| DD (1) | DD291926A5 (pt) |
| DE (1) | DE69028520T2 (pt) |
| DK (1) | DK0458855T3 (pt) |
| EG (1) | EG19075A (pt) |
| ES (1) | ES2091818T3 (pt) |
| FI (1) | FI101452B1 (pt) |
| GR (1) | GR1000639B (pt) |
| HU (1) | HU209915B (pt) |
| IE (1) | IE900459L (pt) |
| IL (1) | IL93242A (pt) |
| IS (1) | IS1678B (pt) |
| MY (1) | MY106487A (pt) |
| NO (1) | NO178883C (pt) |
| NZ (1) | NZ232381A (pt) |
| PH (1) | PH27203A (pt) |
| PT (1) | PT93141A (pt) |
| SE (1) | SE463349B (pt) |
| WO (1) | WO1990009186A1 (pt) |
| YU (1) | YU23490A (pt) |
| ZA (1) | ZA90692B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5705152A (en) * | 1990-10-26 | 1998-01-06 | Interprise Limited | Antimicrobial composition |
| AUPN698495A0 (en) * | 1995-12-06 | 1996-01-04 | Pharma Pacific Pty Ltd | Improved therapeutic formulation and method |
| SE511648C2 (sv) * | 1998-04-17 | 1999-11-01 | Bacterum Ab | Streptokockpreparat för behandling av öroninflammation |
| ES2286038T3 (es) * | 1999-10-12 | 2007-12-01 | Blis Technologies Limited | Lantibiotico. |
| DE10139039A1 (de) * | 2001-08-08 | 2003-05-08 | Zinon Douvlis | Medikamentöse Suppression maligner Proliferationsprozesse durch Aminosäuren und Aminosäurenbindungen orientierte Reaktionen |
| US20110256179A1 (en) | 2008-11-17 | 2011-10-20 | Essum Ab | Pharmaceutical preparation comprising a combination of streptococcus strains and lactobacillus strains |
| US10863753B2 (en) | 2015-10-01 | 2020-12-15 | The Governing Council Of The University Of Toronto | Iron-fortified tea preparations and methods of making same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1195613A (en) * | 1981-02-17 | 1985-10-22 | Forsyth Dental Infirmary For Children | Method of treating periodontosis |
| US4454109A (en) * | 1981-02-17 | 1984-06-12 | Forsyth Dental Infirmary For Children | Method of treating periodontosis |
| JPS5927833A (ja) * | 1982-08-06 | 1984-02-14 | Advance Res & Dev Co Ltd | コレステロール乃至トリグリセリド低下剤 |
-
1989
- 1989-02-15 SE SE8900510A patent/SE463349B/sv not_active IP Right Cessation
-
1990
- 1990-01-30 ZA ZA90692A patent/ZA90692B/xx unknown
- 1990-02-01 IL IL9324290A patent/IL93242A/en not_active IP Right Cessation
- 1990-02-05 NZ NZ232381A patent/NZ232381A/en unknown
- 1990-02-07 YU YU23490A patent/YU23490A/sh unknown
- 1990-02-08 PH PH40021A patent/PH27203A/en unknown
- 1990-02-09 IE IE900459A patent/IE900459L/xx unknown
- 1990-02-12 AT AT90903444T patent/ATE142503T1/de not_active IP Right Cessation
- 1990-02-12 GR GR900100092A patent/GR1000639B/el unknown
- 1990-02-12 CA CA002047189A patent/CA2047189A1/en not_active Abandoned
- 1990-02-12 ES ES90903444T patent/ES2091818T3/es not_active Expired - Lifetime
- 1990-02-12 DK DK90903444.9T patent/DK0458855T3/da active
- 1990-02-12 EP EP90903444A patent/EP0458855B1/en not_active Expired - Lifetime
- 1990-02-12 HU HU901920A patent/HU209915B/hu not_active IP Right Cessation
- 1990-02-12 WO PCT/SE1990/000089 patent/WO1990009186A1/en not_active Ceased
- 1990-02-12 DE DE69028520T patent/DE69028520T2/de not_active Expired - Fee Related
- 1990-02-12 AU AU51577/90A patent/AU628493B2/en not_active Ceased
- 1990-02-13 EG EG7290A patent/EG19075A/xx active
- 1990-02-14 DD DD90337852A patent/DD291926A5/de unknown
- 1990-02-14 PT PT93141A patent/PT93141A/pt not_active Application Discontinuation
- 1990-02-14 IS IS3547A patent/IS1678B/is unknown
- 1990-02-15 MY MYPI90000256A patent/MY106487A/en unknown
- 1990-02-15 AR AR90316173A patent/AR247099A1/es active
- 1990-02-15 CS CS90748A patent/CS74890A2/cs unknown
- 1990-02-15 CN CN90101773A patent/CN1046099A/zh active Pending
-
1991
- 1991-08-13 NO NO913162A patent/NO178883C/no not_active IP Right Cessation
- 1991-08-14 FI FI913845A patent/FI101452B1/fi active
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1994
- 1994-02-10 US US08/194,753 patent/US5378459A/en not_active Expired - Fee Related
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