SE451849B - Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter - Google Patents

Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter

Info

Publication number
SE451849B
SE451849B SE8505842A SE8505842A SE451849B SE 451849 B SE451849 B SE 451849B SE 8505842 A SE8505842 A SE 8505842A SE 8505842 A SE8505842 A SE 8505842A SE 451849 B SE451849 B SE 451849B
Authority
SE
Sweden
Prior art keywords
substance
enzyme
aglycone
acceptor
man
Prior art date
Application number
SE8505842A
Other languages
English (en)
Swedish (sv)
Other versions
SE8505842L (sv
SE8505842D0 (sv
Inventor
K G I Nilsson
Original Assignee
Svenska Sockerfabriks Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Svenska Sockerfabriks Ab filed Critical Svenska Sockerfabriks Ab
Priority to SE8505842A priority Critical patent/SE451849B/sv
Publication of SE8505842D0 publication Critical patent/SE8505842D0/xx
Priority to EP86850414A priority patent/EP0226563A1/en
Priority to US07/938,703 priority patent/US4918009A/en
Priority to DK589386A priority patent/DK589386A/da
Priority to NO864956A priority patent/NO864956L/no
Priority to CA000524898A priority patent/CA1339112C/en
Priority to JP61295689A priority patent/JP2716117B2/ja
Publication of SE8505842L publication Critical patent/SE8505842L/
Publication of SE451849B publication Critical patent/SE451849B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/12—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
SE8505842A 1985-12-11 1985-12-11 Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter SE451849B (sv)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE8505842A SE451849B (sv) 1985-12-11 1985-12-11 Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter
EP86850414A EP0226563A1 (en) 1985-12-11 1986-12-02 A method of controlling the regioselectivity of glycosidic bonds
US07/938,703 US4918009A (en) 1985-12-11 1986-12-04 Method of controlling the regioselectivity of glycosidic bonds
DK589386A DK589386A (da) 1985-12-11 1986-12-08 Fremgangsmaade til styring af omraadeselektiviteten til glykosidbindinger
NO864956A NO864956L (no) 1985-12-11 1986-12-09 Fremgangsmaate for styring av regioselektiviteten for glykosidbindinger.
CA000524898A CA1339112C (en) 1985-12-11 1986-12-10 Method of controlling the regioselectivity of glycosidic bonds
JP61295689A JP2716117B2 (ja) 1985-12-11 1986-12-11 グリコシド結合のレジオセレクテイビテイの制御方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8505842A SE451849B (sv) 1985-12-11 1985-12-11 Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter

Publications (3)

Publication Number Publication Date
SE8505842D0 SE8505842D0 (sv) 1985-12-11
SE8505842L SE8505842L (sv) 1987-06-12
SE451849B true SE451849B (sv) 1987-11-02

Family

ID=20362418

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8505842A SE451849B (sv) 1985-12-11 1985-12-11 Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter

Country Status (7)

Country Link
US (1) US4918009A (da)
EP (1) EP0226563A1 (da)
JP (1) JP2716117B2 (da)
CA (1) CA1339112C (da)
DK (1) DK589386A (da)
NO (1) NO864956L (da)
SE (1) SE451849B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993003168A1 (en) * 1991-08-06 1993-02-18 Kurt Nilsson Enzymatic method for synthesis of carbohydrates

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332880C (en) * 1986-10-17 1994-11-08 Takashi Adachi Plant cultivation method
DE3722812A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Disaccharidfluoride, verfahren zur enzymatischen herstellung mit(alpha)-glycosylfluoriden als substraten
SE466403B (sv) * 1988-03-24 1992-02-10 Kurt G I Nilsson Saett att syntetisera oligosackarider
US5874261A (en) * 1988-09-02 1999-02-23 The Trustees Of The University Of Pennsylvania Method for the purification of glycosyltransferases
SE466521B (sv) * 1988-10-03 1992-02-24 Kurt G I Nilsson Reagens vid analys bestaaende av ett enzym och en annan ligand, vilka aer kovalent bundna till en vattenoloeslig partikel med en diameter paa mindre aen 500 aa
SE465516B (sv) * 1989-08-18 1991-09-23 Kurt G I Nilsson Saett att framstaella en oligosackaridfoerening varvid glykosidas fraan en mollusk anvaendes
WO1991008748A1 (en) * 1989-12-13 1991-06-27 Glycomed Incorporated Synthesis of rotavirus receptor saccharides
WO1991008747A1 (en) * 1989-12-13 1991-06-27 Glycomed Incorporated Synthetic receptor molecules recognizable by a rotavirus
US5583042A (en) * 1990-04-16 1996-12-10 Neose Pharmaceuticals, Inc. Apparatus for the synthesis of saccharide compositions
DE69133122D1 (de) 1990-04-16 2002-11-07 Univ Pennsylvania Saccharidzusammensetzungen, Verfahren und Apparate zu deren Synthese
US5180674A (en) * 1990-04-16 1993-01-19 The Trustees Of The University Of Pennsylvania Saccharide compositions, methods and apparatus for their synthesis
DE4013077A1 (de) * 1990-04-25 1991-10-31 Hoechst Ag Verfahren zur glycosidasekatalysierten synthese von glycokonjugaten
US5461143A (en) * 1991-03-18 1995-10-24 The Scripps Research Institute Oligosaccharide enzyme substrates and inhibitors: methods and compositions
US5278299A (en) * 1991-03-18 1994-01-11 Scripps Clinic And Research Foundation Method and composition for synthesizing sialylated glycosyl compounds
CA2106301C (en) 1991-03-18 1999-04-06 Chi-Huey Wong Oligosaccharide enzyme substrates and inhibitors: method and compositions
US6518051B1 (en) 1991-04-11 2003-02-11 The Trustees Of The University Of Pennsylvania Saccharide compositions, methods and apparatus for their synthesis
JP2782563B2 (ja) * 1991-05-15 1998-08-06 寳酒造株式会社 新規糖質加水分解酵素
US5403726A (en) * 1991-07-30 1995-04-04 The Scripps Research Institute Enzymatic process for producing a galactosylβ1,3glycal disaccaride using β-galactosidase
WO1993005076A1 (en) * 1991-08-30 1993-03-18 Glyko, Inc. Fluorophore assisted derivatization analysis of carbohydrates
EP0551107A2 (de) * 1992-01-09 1993-07-14 Hoechst Aktiengesellschaft Verfahren zur beta-Galactosidase-katalysierten Transglycosidierung mit unphysiologischen Glycosyldonoren
DE69316754T2 (de) * 1992-06-01 1998-07-16 Biomembrane Inst Schrittweise entfernung von monosacchariden vom reduzierenden ende von oligosacchariden und verwendungen davon
SE9301270D0 (sv) 1993-04-19 1993-04-17 Biosensor
US5374541A (en) * 1993-05-04 1994-12-20 The Scripps Research Institute Combined use of β-galactosidase and sialyltransferase coupled with in situ regeneration of CMP-sialic acid for one pot synthesis of oligosaccharides
US5409817A (en) * 1993-05-04 1995-04-25 Cytel, Inc. Use of trans-sialidase and sialyltransferase for synthesis of sialylα2→3βgalactosides
US5936075A (en) * 1994-05-17 1999-08-10 Bioflexin Ab Amino-deoxy-disaccharides and amino-deoxy-oligosaccharides
SE9301677L (sv) * 1993-05-14 1994-11-18 Kurt G I Nilsson Syntesmetod
US6183994B1 (en) 1993-05-14 2001-02-06 Bioflexin Ab N-containing saccharides and method for the synthesis of N-containing saccharides from amino-deoxy-disaccharides and amino-deoxy-oligosaccharides
JP3020811B2 (ja) * 1993-08-23 2000-03-15 寳酒造株式会社 糖鎖構造決定方法
SE9304316D0 (sv) * 1993-12-24 1993-12-24 Kurt Nilsson Aminosyra-konjugat
SE9400034D0 (sv) 1994-01-06 1994-01-06 Glycorex Ab Laktosaminderivat
DE69521074T2 (de) * 1994-03-30 2001-09-13 Takara Shuzo Co., Ltd. Transglykosylierungsverfahren zur Herstellung eines Kohlenhydrats oder eines Glykokonjugates
ATE195147T1 (de) * 1994-09-06 2000-08-15 Ab Bioflexin Aminosäuren konjugaten
US6127153A (en) * 1995-06-07 2000-10-03 Neose Technologies, Inc. Method of transferring at least two saccharide units with a polyglycosyltransferase, a polyglycosyltransferase and gene encoding a polyglycosyltransferase
US6284494B1 (en) 1995-12-12 2001-09-04 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides using mutant glycosidase enzymes
CA2165041C (en) * 1995-12-12 2005-07-05 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides, and the products formed thereby
US5716812A (en) * 1995-12-12 1998-02-10 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides, and the products formed thereby
WO1997021822A2 (en) * 1995-12-12 1997-06-19 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides using mutant glycosidase enzymes
AU1404597A (en) * 1995-12-21 1997-07-17 Procur Ab Galactopyranosides and their use
US7014049B2 (en) * 1996-12-23 2006-03-21 Glycorex Transplantation Ab Device for bio-affinity material
JP4544663B2 (ja) * 1999-06-21 2010-09-15 生化学工業株式会社 デアミノノイラミン酸誘導体、デアミノノイラミニダーゼの精製方法及びデアミノノイラミン酸結合性物質の検出方法
ES2381530T3 (es) * 2000-03-31 2012-05-29 Opentv, Inc. Sistema y método para la inserción de metadatos locales
EP1205555A1 (de) * 2000-11-08 2002-05-15 Solvent Innovation GmbH Enzymkatalyse in Gegenwart ionischer Flüssigkeiten
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
AU2004236174B2 (en) 2001-10-10 2011-06-02 Novo Nordisk A/S Glycopegylation methods and proteins/peptides produced by the methods
US7214660B2 (en) * 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
WO2004033502A1 (ja) * 2002-10-08 2004-04-22 Ricom Corporation キトサン含有多糖、その製造方法及び用途
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US7137903B2 (en) 2004-04-21 2006-11-21 Acushnet Company Transitioning hollow golf clubs
JP2005334648A (ja) 2004-04-21 2005-12-08 Acushnet Co 変移する中空タイプのゴルフクラブ
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
DK2586456T3 (da) 2004-10-29 2016-03-21 Ratiopharm Gmbh Omdannelse og glycopegylering af fibroblast vækstfaktor (FGF)
EP1858543B1 (en) * 2005-01-10 2013-11-27 BioGeneriX AG Glycopegylated granulocyte colony stimulating factor
EP2386571B1 (en) * 2005-04-08 2016-06-01 ratiopharm GmbH Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) * 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
CN102719508A (zh) * 2005-08-19 2012-10-10 诺和诺德公司 糖基聚乙二醇化的因子vii和因子viia
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
EP2049144B8 (en) * 2006-07-21 2015-02-18 ratiopharm GmbH Glycosylation of peptides via o-linked glycosylation sequences
US20100075375A1 (en) * 2006-10-03 2010-03-25 Novo Nordisk A/S Methods for the purification of polypeptide conjugates
LT2068907T (lt) * 2006-10-04 2018-01-10 Novo Nordisk A/S Glicerolio sujungti pegilinti sacharidai ir glikopeptidai
CN101796063B (zh) * 2007-04-03 2017-03-22 拉蒂奥法姆有限责任公司 使用糖聚乙二醇化g‑csf的治疗方法
ES2551123T3 (es) 2007-06-12 2015-11-16 Ratiopharm Gmbh Proceso mejorado para la producción de azúcares de nucleótido
CA2711503A1 (en) * 2008-01-08 2009-07-16 Biogenerix Ag Glycoconjugation of polypeptides using oligosaccharyltransferases
MX2010009154A (es) 2008-02-27 2010-09-09 Novo Nordisk As Moleculas conjugadas del factor viii.
EP2138586A1 (en) * 2008-06-24 2009-12-30 Cognis IP Management GmbH Process for the regioselective preparation of disaccharides or oligosaccharides
US8580538B2 (en) 2010-07-29 2013-11-12 Basf Se Enzymatic production of an ethylenically unsaturated glycoside
BR112013001944A2 (pt) * 2010-07-29 2018-05-15 Basf Se método para produzir um glicosídeo etilenicamente insaturado

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5432073B2 (da) * 1971-10-14 1979-10-11
FR2263747B1 (da) * 1974-03-12 1977-12-02 Roussel Uclaf
JPS545070A (en) * 1977-06-13 1979-01-16 Hayashibara Biochem Lab Production of sweetening agent
AT362526B (de) * 1977-09-13 1981-05-25 Boehringer Mannheim Gmbh Verfahren und reagens zur bestimmung von alpha- -amylase
US4225672A (en) * 1979-02-27 1980-09-30 Hall Leo M Method for producing maltooligosaccharide glycosides
DE3000292A1 (de) * 1980-01-05 1981-07-09 Behringwerke Ag, 3550 Marburg Indoxylmaltodextrine, verfahren zu ihrer herstellung und ihre verwendung
SE8203925D0 (sv) * 1982-06-23 1982-06-23 Svenska Sockerfabriks Ab New and novel glycosides, glycoconjugates and processes for their preparation
JPS5939268A (ja) * 1982-08-30 1984-03-03 Sanyo Kokusaku Pulp Co Ltd 甘味料の製造法
GB8316790D0 (en) * 1983-06-21 1983-07-27 Tate & Lyle Plc Chemical process
JPS6183195A (ja) * 1984-08-24 1986-04-26 Wako Pure Chem Ind Ltd 新規なオリゴサツカライド誘導体、及びこれを基質として用いるα−アミラ−ゼ活性測定法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993003168A1 (en) * 1991-08-06 1993-02-18 Kurt Nilsson Enzymatic method for synthesis of carbohydrates
US5532147A (en) * 1991-08-06 1996-07-02 Nilsson; Kurt Enzymatic method for synthesis of carbohydrates

Also Published As

Publication number Publication date
US4918009A (en) 1990-04-17
SE8505842L (sv) 1987-06-12
NO864956D0 (no) 1986-12-09
DK589386D0 (da) 1986-12-08
CA1339112C (en) 1997-07-29
JPS62240695A (ja) 1987-10-21
SE8505842D0 (sv) 1985-12-11
DK589386A (da) 1987-06-12
JP2716117B2 (ja) 1998-02-18
EP0226563A1 (en) 1987-06-24
NO864956L (no) 1987-06-12

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