SE448819B - Pulver och suspension av mikrokapslad bakampicillin-syraadditionssalt - Google Patents

Pulver och suspension av mikrokapslad bakampicillin-syraadditionssalt

Info

Publication number
SE448819B
SE448819B SE8104974A SE8104974A SE448819B SE 448819 B SE448819 B SE 448819B SE 8104974 A SE8104974 A SE 8104974A SE 8104974 A SE8104974 A SE 8104974A SE 448819 B SE448819 B SE 448819B
Authority
SE
Sweden
Prior art keywords
suspension
acid addition
addition salt
powder
coating
Prior art date
Application number
SE8104974A
Other languages
English (en)
Swedish (sv)
Other versions
SE8104974L (sv
Inventor
M L Beatty
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SE8104974L publication Critical patent/SE8104974L/
Publication of SE448819B publication Critical patent/SE448819B/sv

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
SE8104974A 1980-08-22 1981-08-21 Pulver och suspension av mikrokapslad bakampicillin-syraadditionssalt SE448819B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/180,537 US4321253A (en) 1980-08-22 1980-08-22 Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration

Publications (2)

Publication Number Publication Date
SE8104974L SE8104974L (sv) 1982-02-23
SE448819B true SE448819B (sv) 1987-03-23

Family

ID=22660812

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8104974A SE448819B (sv) 1980-08-22 1981-08-21 Pulver och suspension av mikrokapslad bakampicillin-syraadditionssalt

Country Status (41)

Country Link
US (1) US4321253A (fr)
JP (1) JPS5775986A (fr)
KR (1) KR860000513B1 (fr)
AR (1) AR227201A1 (fr)
AT (1) AT370994B (fr)
AU (1) AU529965B2 (fr)
BE (1) BE890028A (fr)
BG (1) BG42000A3 (fr)
CA (1) CA1137414A (fr)
CH (1) CH650674A5 (fr)
CS (1) CS225845B2 (fr)
DD (1) DD201644A5 (fr)
DE (1) DE3132614C2 (fr)
DK (1) DK158971C (fr)
DZ (1) DZ315A1 (fr)
ES (1) ES8303091A1 (fr)
FI (1) FI72647C (fr)
FR (1) FR2488798A1 (fr)
GB (1) GB2082539B (fr)
GR (1) GR74983B (fr)
HK (1) HK43786A (fr)
HU (1) HU188679B (fr)
IE (1) IE51506B1 (fr)
IL (1) IL63617A (fr)
IN (1) IN156538B (fr)
IT (1) IT1138161B (fr)
KE (1) KE3626A (fr)
LU (1) LU83572A1 (fr)
MX (1) MX5731A (fr)
MY (1) MY8600597A (fr)
NL (1) NL191978C (fr)
NO (1) NO154821C (fr)
NZ (1) NZ198106A (fr)
PH (1) PH17125A (fr)
PL (1) PL232141A1 (fr)
PT (1) PT73555B (fr)
RO (1) RO82679B (fr)
SE (1) SE448819B (fr)
SU (1) SU1364226A3 (fr)
YU (1) YU43985B (fr)
ZA (1) ZA815793B (fr)

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CH647676A5 (fr) * 1978-12-22 1985-02-15 Donald E Panoz Formes galeniques a usage oral, a liberation programmee et leurs procedes de preparation.
SE8103843L (sv) * 1981-06-18 1982-12-19 Astra Laekemedel Ab Farmaceutisk mixtur
SE8203953D0 (sv) * 1982-06-24 1982-06-24 Astra Laekemedel Ab Pharmaceutical mixture
US4994260A (en) * 1982-05-28 1991-02-19 Astra Lakemedel Aktiebolag Pharmaceutical mixture
WO1984000004A1 (fr) * 1982-06-14 1984-01-05 Key Pharma Aspirine a liberation entretenue
US4508702A (en) * 1982-06-14 1985-04-02 Key Pharmaceuticals, Inc. Sustained release aspirin
US4634587A (en) * 1982-07-09 1987-01-06 Key Pharmaceuticals, Inc. Sustained release quinidine dosage form
EP0113373B1 (fr) * 1982-07-09 1991-08-28 Key Pharmaceuticals, Inc. Forme de dosage de quinidine a liberation entretenue
AU569277B2 (en) * 1983-03-03 1988-01-28 Dow Chemical Company, The Aqueuos dispersion of water-insoluble organophilic cellulose ether for sustained release of active agents
US4555399A (en) * 1983-11-18 1985-11-26 Key Pharmaceuticals, Inc. Aspirin tablet
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
SE8405611D0 (sv) * 1984-11-09 1984-11-09 Astra Laekemedel Ab Process for stabilization of bacampicillin hydrochloride
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
US4853229A (en) * 1987-10-26 1989-08-01 Alza Corporation Method for adminstering tiny pills
US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
NZ252433A (en) * 1992-04-30 1996-07-26 Schering Corp Preparation of a dry hydrated cephalosporin powder formulation which is resistant to air oxidation and dehydration by mixing the drug with dry excipients and filling into a sealable storage container
US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
US6270804B1 (en) * 1998-04-03 2001-08-07 Biovail Technologies Ltd. Sachet formulations
IN191482B (fr) * 1999-03-19 2003-12-06 Ranbaxy Lab Ltd
JP4711478B2 (ja) * 1999-08-13 2011-06-29 旭化成ケミカルズ株式会社 味がマスクされた薬物
US20050037086A1 (en) * 1999-11-19 2005-02-17 Zycos Inc., A Delaware Corporation Continuous-flow method for preparing microparticles
EP1712222A3 (fr) 1999-12-23 2012-06-20 Pfizer Products Inc. Compositions pharmaceutiques fournissant des concentrations de médicaments améliorées
EP1118333A1 (fr) * 2000-01-18 2001-07-25 Eurand International S.P.A. Compositions avec une biodisponibilité orale augmentée
US6551617B1 (en) 2000-04-20 2003-04-22 Bristol-Myers Squibb Company Taste masking coating composition
ES2284643T3 (es) 2000-04-20 2007-11-16 Novartis Ag Composicion de revestimiento enmascarante del sabor.
JP2003535122A (ja) * 2000-06-02 2003-11-25 ザイコス インク. 生物活性物質のための送達システム
FR2822834B1 (fr) * 2001-04-02 2005-02-25 Flamel Tech Sa Suspension colloidale de nanoparticules a base de copolymeres amphiphile pour la vectorisation de principes actifs et leur mode de preparation
US20030096791A1 (en) * 2001-05-31 2003-05-22 Cima Labs Inc. Taste masking of highly water-soluble drugs
KR20030015655A (ko) * 2001-08-17 2003-02-25 한미약품공업 주식회사 항암제의 경구흡수율을 증가시키는 인단계 화합물의결정성 산부가염, 이의 제조방법 및 이를 함유하는 약학적조성물
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
FR2830447B1 (fr) * 2001-10-09 2004-04-16 Flamel Tech Sa Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
IL164221A0 (en) * 2002-04-09 2005-12-18 Flamel Tech Sa Oral pharmaceutical formulation in the form of aqueous suspension of microcapsules for modified release of amoxicillim
CA2480826C (fr) 2002-04-09 2012-02-07 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
FR2842736B1 (fr) 2002-07-26 2005-07-22 Flamel Tech Sa Formulation pharmaceutique orale sous forme d'une pluralite de microcapsules permettant la liberation prolongee de principe(s) actif(s) peu soluble(s)
FR2842735B1 (fr) * 2002-07-26 2006-01-06 Flamel Tech Sa Microcapsules a liberation modifiee de principes actifs peu solubles pour l'administration per os
FR2843117B1 (fr) * 2002-07-30 2004-10-15 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
FR2860516B1 (fr) * 2003-10-03 2006-01-13 Flamel Tech Sa Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
FR2862536B1 (fr) * 2003-11-21 2007-11-23 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques
US7244765B2 (en) * 2004-06-25 2007-07-17 Cytokine Pharmasciences, Inc Guanylhydrazone salts, compositions, processes of making and methods of using
FR2885526B1 (fr) * 2005-05-13 2007-07-27 Flamel Technologies Sa Medicament oral a base d'inhibiteur de pompe a protons
JP6184656B1 (ja) * 2015-10-13 2017-08-23 テクノガード株式会社 胃腸管粘膜保護組成物

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US3549746A (en) * 1967-11-02 1970-12-22 Bristol Myers Co Antibiotic composition
US3873521A (en) * 1970-09-17 1975-03-25 Astra Laekemedel Ab Esters of {60 -amino penicillins
ZA718014B (en) 1970-12-23 1972-08-30 Beecham Group Ltd Pharmaceutical formulations
US4016254A (en) * 1972-05-19 1977-04-05 Beecham Group Limited Pharmaceutical formulations
GB1455296A (en) * 1973-05-24 1976-11-10 Beecham Group Ltd Veterinary treatment
GB1479655A (en) 1974-03-08 1977-07-13 Beecham Group Ltd Antibiotic preparations
US4127647A (en) * 1975-04-08 1978-11-28 Meiji Seika Kaisha, Ltd. Process for preparation of stable amorphous macrolide antibiotic solids
JPS5840529B2 (ja) * 1975-09-29 1983-09-06 明治製菓株式会社 ケイコウヨウセイザイノセイホウ
GB1561301A (en) * 1976-01-02 1980-02-20 Beecham Group Ltd Orally administrable pharmaceutical composition
ZA793935B (en) * 1978-08-04 1980-07-30 Beecham Group Ltd Powders
JPS57105316A (en) * 1980-12-23 1982-06-30 Hitachi Cable Ltd Method of fitting heat-shrinkable tube

Also Published As

Publication number Publication date
CS225845B2 (en) 1984-02-13
NZ198106A (en) 1983-12-16
NL8103902A (nl) 1982-03-16
KE3626A (en) 1986-05-16
CH650674A5 (fr) 1985-08-15
GB2082539A (en) 1982-03-10
US4321253A (en) 1982-03-23
BG42000A3 (en) 1987-09-15
FI72647B (fi) 1987-03-31
HU188679B (en) 1986-05-28
SU1364226A3 (ru) 1987-12-30
AU529965B2 (en) 1983-06-30
IT8123587A0 (it) 1981-08-20
MY8600597A (en) 1986-12-31
DK372181A (da) 1982-02-23
IT1138161B (it) 1986-09-17
PH17125A (en) 1984-06-01
CA1137414A (fr) 1982-12-14
DK158971B (da) 1990-08-13
NO812827L (no) 1982-02-23
GR74983B (fr) 1984-07-12
RO82679B (ro) 1984-07-30
FR2488798B1 (fr) 1985-01-11
DD201644A5 (de) 1983-08-03
MX5731A (es) 1993-11-01
PL232141A1 (fr) 1982-03-15
ATA362781A (de) 1982-10-15
RO82679A (fr) 1984-05-23
SE8104974L (sv) 1982-02-23
BE890028A (fr) 1982-02-22
AT370994B (de) 1983-05-25
YU43985B (en) 1990-02-28
PT73555A (en) 1981-09-01
GB2082539B (en) 1984-01-18
DE3132614C2 (de) 1985-08-22
DE3132614A1 (de) 1982-05-19
AR227201A1 (es) 1982-09-30
NO154821B (no) 1986-09-22
ZA815793B (en) 1982-08-25
JPH0248525B2 (fr) 1990-10-25
IE811911L (en) 1982-02-22
IN156538B (fr) 1985-08-31
NO154821C (no) 1987-01-07
DZ315A1 (fr) 2004-09-13
KR860000513B1 (ko) 1986-05-02
NL191978B (nl) 1996-08-01
FI72647C (fi) 1987-07-10
IL63617A0 (en) 1981-11-30
FI812574L (fi) 1982-02-23
DK158971C (da) 1991-01-07
ES504905A0 (es) 1983-02-01
FR2488798A1 (fr) 1982-02-26
HK43786A (en) 1986-06-20
LU83572A1 (fr) 1982-04-14
ES8303091A1 (es) 1983-02-01
NL191978C (nl) 1996-12-03
KR830005850A (ko) 1983-09-14
YU201781A (en) 1984-04-30
JPS5775986A (en) 1982-05-12
IE51506B1 (en) 1987-01-07
AU7441681A (en) 1982-04-01
IL63617A (en) 1984-11-30
PT73555B (en) 1983-07-14

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