SE440656B - Sett att framstella 16-metyl-9alfa-halogen-prednisolonestrar och -etrar - Google Patents
Sett att framstella 16-metyl-9alfa-halogen-prednisolonestrar och -etrarInfo
- Publication number
- SE440656B SE440656B SE7803041A SE7803041A SE440656B SE 440656 B SE440656 B SE 440656B SE 7803041 A SE7803041 A SE 7803041A SE 7803041 A SE7803041 A SE 7803041A SE 440656 B SE440656 B SE 440656B
- Authority
- SE
- Sweden
- Prior art keywords
- group
- methyl
- tetrahydropyran
- chloro
- diesters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
- C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT6163774 | 1974-03-27 | ||
| PT6163674 | 1974-03-27 | ||
| PT6163675 | 1975-03-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7803041L SE7803041L (sv) | 1978-03-16 |
| SE440656B true SE440656B (sv) | 1985-08-12 |
Family
ID=27354092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7803041A SE440656B (sv) | 1974-03-27 | 1978-03-16 | Sett att framstella 16-metyl-9alfa-halogen-prednisolonestrar och -etrar |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE827275A (enExample) |
| CH (2) | CH622811A5 (enExample) |
| DK (1) | DK153556C (enExample) |
| FR (1) | FR2274309A1 (enExample) |
| GB (2) | GB1511820A (enExample) |
| IE (2) | IE41138B1 (enExample) |
| NZ (1) | NZ177056A (enExample) |
| SE (1) | SE440656B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR890000664B1 (ko) * | 1981-10-19 | 1989-03-22 | 바리 안소니 뉴우샘 | 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법 |
| IT1285770B1 (it) | 1996-10-04 | 1998-06-18 | Nicox Sa | Composti corticoidei |
| CN102516348B (zh) * | 2011-11-10 | 2013-11-13 | 中国科学院上海有机化学研究所 | 一种16s-甲基-20s-羟基孕甾化合物、合成方法及其用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1070751A (en) * | 1964-01-28 | 1967-06-01 | Glaxo Lab Ltd | 17-esters of 17-hydroxy-21-desoxy-steroids |
| GB1139505A (en) * | 1965-06-23 | 1969-01-08 | Glaxo Lab Ltd | A process for the production of 17-‡-monoesters of 17-‡-hydroxy-20-keto-steroids |
| CH481085A (de) * | 1965-08-30 | 1969-11-15 | Scherico Ltd | Verfahren zur Herstellung von 11B-Hydroxy-17 -alkanoyloxysteroiden der Pregnanreihe |
| US3383394A (en) * | 1965-08-30 | 1968-05-14 | Schering Corp | Novel 17-acylating process and products thereof |
| BE788355A (fr) * | 1971-09-07 | 1973-03-05 | Merck Patent Gmbh | Esters de 9 alpha-fluoro-16-methylene-prednisolone |
-
1975
- 1975-03-26 NZ NZ177056A patent/NZ177056A/xx unknown
- 1975-03-26 GB GB47940/77A patent/GB1511820A/en not_active Expired
- 1975-03-26 GB GB12608/75A patent/GB1510617A/en not_active Expired
- 1975-03-26 CH CH392475A patent/CH622811A5/de not_active IP Right Cessation
- 1975-03-26 DK DK129575A patent/DK153556C/da not_active IP Right Cessation
- 1975-03-27 BE BE154849A patent/BE827275A/xx not_active IP Right Cessation
- 1975-03-27 IE IE2062/75A patent/IE41138B1/xx unknown
- 1975-03-27 IE IE693/75A patent/IE41137B1/xx unknown
- 1975-03-27 FR FR7509621A patent/FR2274309A1/fr active Granted
-
1978
- 1978-03-16 SE SE7803041A patent/SE440656B/sv not_active IP Right Cessation
-
1979
- 1979-10-22 CH CH946879A patent/CH625254A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK153556C (da) | 1988-12-05 |
| GB1510617A (en) | 1978-05-10 |
| IE41137B1 (en) | 1979-10-24 |
| FR2274309A1 (fr) | 1976-01-09 |
| DK153556B (da) | 1988-07-25 |
| IE41138B1 (en) | 1979-10-24 |
| CH622811A5 (enExample) | 1981-04-30 |
| SE7803041L (sv) | 1978-03-16 |
| CH625254A5 (enExample) | 1981-09-15 |
| IE41137L (en) | 1975-09-27 |
| FR2274309B1 (enExample) | 1978-11-24 |
| NZ177056A (en) | 1978-09-20 |
| DK129575A (enExample) | 1975-09-28 |
| GB1511820A (en) | 1978-05-24 |
| BE827275A (fr) | 1975-07-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4242334A (en) | Corticoid 17-(alkyl carbonates) and processes for their preparation | |
| EP0004773B1 (en) | 17-beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes, their pharmaceutical use and processes for their preparation | |
| IE45023B1 (en) | Androstadiene-17-carboxylic acids and their esters | |
| DK147735B (da) | Analogifremgangsmaade til fremstilling af 3-oxo-androst-4-en-17beta-thiocarboxylsyreestere | |
| CY1291A (en) | Androstane 17 beta carbothioates | |
| CZ361698A3 (cs) | Deriváty androstenu a farmaceutický prostředek obsahující tyto deriváty | |
| US10112970B2 (en) | Process for the preparation of 17-desoxy-corticosteroids | |
| EP0029151B1 (en) | 6-alpha-fluoro-9-alpha-chloro-prednisolone-17,21 diesters, pharmaceutical compositions containing them and intermediates | |
| US4024131A (en) | 16-Methyl-9α-halo steroid esters, ethers and preparation thereof | |
| KR850001208B1 (ko) | 17α-아실옥시-5β-코르티코이드 및 17α-아실옥시-5α-코르티코이드의 제조방법 | |
| JPS6411037B2 (enExample) | ||
| DK146017B (da) | Analogifremgangsmaade til fremstilling af 17alfa-acyloxy-9alfa,21-dihalogen-11beta-hydroxy-6alfa-fluor-16beta-methyl-pregna-1,4-dien-3,20-dion-forbindelser | |
| US4021459A (en) | Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy 20-keto-pregnenes | |
| US4343739A (en) | Process of selective solvolysis | |
| US4011315A (en) | 21-acetals and mixed acetals of steroidal 21-aldehydes, intermediates and methods of preparation | |
| US4207235A (en) | Selective epoxidation of steroidal bromohydrins | |
| US4323512A (en) | Process for the preparation of steroidal 17α-arylcarboxylates | |
| JPS5899500A (ja) | ３―クロロ―プレグナン誘導体、その製造法および医薬組成物 | |
| JPS5922719B2 (ja) | １６↓−メチル−９α−ハロステロイドのエステル及びエ−テル誘導体 | |
| US3996358A (en) | 21-Esters of steroidal-21-aldehyde hydrates and 21-aldehyde hemiacetals and methods of preparation | |
| US3980680A (en) | Process for the preparation of 21-desoxy-17-acyloxy-4-pregnenes and of 21-iodo-21-desoxy-17-acyl oxy-4-pregnene intermediates useful therein | |
| US4602009A (en) | Corticoid derivatives and process for production thereof | |
| US3947409A (en) | 16-Alkyl-1,4,9(11)-pregnatrienes and 9,11-epoxides thereof | |
| US4001219A (en) | Steroidal derivatives of bendazolic acid and process for the preparation of the same | |
| US3631076A (en) | Process for preparing 16-unsaturated steroids |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAL | Patent in force |
Ref document number: 7803041-8 Format of ref document f/p: F |
|
| NUG | Patent has lapsed |
Ref document number: 7803041-8 Format of ref document f/p: F |