SE435383B - Pyrido(1,2-a)pyrimidinderivat och farmaceutiska beredningar innehallande dem - Google Patents

Pyrido(1,2-a)pyrimidinderivat och farmaceutiska beredningar innehallande dem

Info

Publication number
SE435383B
SE435383B SE7808770A SE7808770A SE435383B SE 435383 B SE435383 B SE 435383B SE 7808770 A SE7808770 A SE 7808770A SE 7808770 A SE7808770 A SE 7808770A SE 435383 B SE435383 B SE 435383B
Authority
SE
Sweden
Prior art keywords
methyl
oxo
ethyl
pyrimidine
pyrido
Prior art date
Application number
SE7808770A
Other languages
English (en)
Swedish (sv)
Other versions
SE7808770L (sv
Inventor
J Knoll
Z Meszaros
I Hermecz
F Fulop
G Bernath
S Virag
G Nagy
P Szentmiklosi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of SE7808770L publication Critical patent/SE7808770L/xx
Publication of SE435383B publication Critical patent/SE435383B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7808770A 1977-08-19 1978-08-18 Pyrido(1,2-a)pyrimidinderivat och farmaceutiska beredningar innehallande dem SE435383B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77CI1765A HU178910B (en) 1977-08-19 1977-08-19 Process for preparing 2,3-disubstituted-4-oxo-4h-pyrido/1,2-a/-pyrimidines

Publications (2)

Publication Number Publication Date
SE7808770L SE7808770L (sv) 1979-02-20
SE435383B true SE435383B (sv) 1984-09-24

Family

ID=10994667

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7808770A SE435383B (sv) 1977-08-19 1978-08-18 Pyrido(1,2-a)pyrimidinderivat och farmaceutiska beredningar innehallande dem

Country Status (22)

Country Link
US (2) US4219649A (nl)
JP (1) JPS5448795A (nl)
AT (1) AT368156B (nl)
AU (1) AU518364B2 (nl)
BE (1) BE869832A (nl)
CA (1) CA1152989A (nl)
CH (1) CH637541A5 (nl)
CS (1) CS238901B1 (nl)
DD (1) DD138320A5 (nl)
DE (1) DE2835004A1 (nl)
DK (1) DK160045C (nl)
ES (1) ES473181A1 (nl)
FI (1) FI66864C (nl)
FR (1) FR2416892A1 (nl)
GB (1) GB2006187B (nl)
GR (1) GR64913B (nl)
HU (1) HU178910B (nl)
IL (1) IL55338A (nl)
NL (1) NL7808570A (nl)
SE (1) SE435383B (nl)
SU (1) SU906378A3 (nl)
YU (1) YU40985B (nl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU179143B (en) * 1977-12-29 1982-08-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydroxy-groops-containing 6,7-dihydro-pyrido-square bracket-1,2-a-square bracket closed-pyrimidin derivatives and esters thereof
HU180701B (en) * 1977-12-29 1983-04-29 Chinoin Gyogyszer Es Vegyeszet Process for preparing pyrido-/1,2-a/pyrimidines containing a carboxylic or ester group on the pirimidimering
FR2449689A1 (fr) * 1979-02-20 1980-09-19 Logeais Labor Jacques Nouveaux derives condenses de pyrrolidine ou de piperidine, leur procede de preparation et leurs applications en therapeutique
IL59802A (en) 1979-05-08 1983-07-31 Erba Farmitalia Substituted pyrido(1,2-a)pyrimidine carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
PL129612B1 (en) * 1980-07-24 1984-05-31 Rhone Poulenc Ind Process for preparing novel derivatives of 2,3,6,7-tetrahydrothiazole/3,2-a/pirymidin-5-one
HU183408B (en) * 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
CA1211111A (en) * 1982-02-15 1986-09-09 Isao Yanagisawa Process for preparing novel pyrimidone compounds
US5252572A (en) * 1988-02-03 1993-10-12 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
EP0527889B1 (en) * 1990-05-02 2000-08-02 Abbott Laboratories Quinolizinone type compounds
DE10050662A1 (de) * 2000-10-13 2002-04-18 Gruenenthal Gmbh Substituierte 3,4-Dihydro-pyrido[1,2-a]pyrimidine
DE10050661A1 (de) * 2000-10-13 2002-04-18 Gruenenthal Gmbh Substituierte 3,4-Dihydro-pyrimido[1,2-a]pyrimidine und 3,4-Dihydro-pyrazino[1,2-a]pyrimidine
DE20202183U1 (de) 2002-02-01 2002-06-06 Kretzschmar Michael Baukasten
EP2210892A3 (en) * 2002-10-04 2010-10-27 Prana Biotechnology Limited Neurologically-active compounds
ZA200809493B (en) * 2006-04-14 2010-08-25 Prana Biotechnology Ltd Method of treatment of age-related macular degeneration (AMD)
US7955155B2 (en) 2007-07-09 2011-06-07 Mega Brands International Magnetic and electronic toy construction systems and elements
JP5649304B2 (ja) * 2007-11-13 2015-01-07 国立大学法人 東京大学 クオラムセンシング阻害剤
CN103983627A (zh) * 2008-06-17 2014-08-13 韩国巴斯德研究所 作为抗结核病药的吡啶并嘧啶化合物
AU2015358284B2 (en) * 2014-12-02 2020-07-02 Prana Biotechnology Limited 4H-pyrido[1,2-a]pyrimidin-4-one compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT294107B (de) * 1966-11-02 1971-11-10 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
HU169230B (nl) * 1972-03-29 1976-10-28
HU168014B (nl) * 1973-03-30 1976-02-28
US4209622A (en) * 1973-03-30 1980-06-24 Chinoin Gygyszer es Vegyeszeti Termekek Gyara Rt. 3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine
HU168541B (nl) * 1973-11-24 1976-05-28
US4022897A (en) * 1974-03-04 1977-05-10 E. R. Squibb & Sons, Inc. CNS active compounds
US3898224A (en) * 1974-09-09 1975-08-05 Squibb & Sons Inc 1,6,7,8-Tetrahydro-4-oxo-4H-pyrido {8 1,2-A{9 pyrimidine-9-carboalkoxy compounds
US3935197A (en) * 1975-05-16 1976-01-27 E. R. Squibb & Sons, Inc. 2-Styryl-4H-pyrido(1,2-a)pyrimidin-4-ones

Also Published As

Publication number Publication date
AU518364B2 (en) 1981-09-24
DK160045C (da) 1991-06-10
DK367478A (da) 1979-02-20
DE2835004C2 (nl) 1989-06-29
US4219649A (en) 1980-08-26
CH637541A5 (de) 1983-08-15
JPS5448795A (en) 1979-04-17
DD138320A5 (de) 1979-10-24
GB2006187B (en) 1982-10-06
IL55338A (en) 1985-10-31
NL7808570A (nl) 1979-02-21
FR2416892B1 (nl) 1983-11-18
FR2416892A1 (fr) 1979-09-07
AT368156B (de) 1982-09-27
HU178910B (en) 1982-07-28
CS238901B1 (en) 1985-12-16
CS541778A1 (en) 1985-05-15
FI66864C (fi) 1984-12-10
SU906378A3 (ru) 1982-02-15
ES473181A1 (es) 1979-04-01
IL55338A0 (en) 1978-10-31
US4291036A (en) 1981-09-22
CA1152989A (en) 1983-08-30
YU196678A (en) 1983-10-31
ATA585278A (de) 1982-01-15
SE7808770L (sv) 1979-02-20
GR64913B (en) 1980-06-09
AU3900978A (en) 1980-02-21
FI782527A (fi) 1979-02-20
DE2835004A1 (de) 1979-03-01
JPS626554B2 (nl) 1987-02-12
FI66864B (fi) 1984-08-31
BE869832A (fr) 1978-12-18
GB2006187A (en) 1979-05-02
DK160045B (da) 1991-01-21
YU40985B (en) 1986-10-31

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