SE435381B - Forfarande for framstellning av hypotensiva 2-(4-furoylpiperazin-1-yl)-4-amino-6,7-dimetoxikinazolin - Google Patents

Forfarande for framstellning av hypotensiva 2-(4-furoylpiperazin-1-yl)-4-amino-6,7-dimetoxikinazolin

Info

Publication number
SE435381B
SE435381B SE7708942A SE7708942A SE435381B SE 435381 B SE435381 B SE 435381B SE 7708942 A SE7708942 A SE 7708942A SE 7708942 A SE7708942 A SE 7708942A SE 435381 B SE435381 B SE 435381B
Authority
SE
Sweden
Prior art keywords
dimetoxicinazoline
furoylpiperazin
amino
procedure
hypotensive
Prior art date
Application number
SE7708942A
Other languages
English (en)
Swedish (sv)
Other versions
SE7708942L (sv
Inventor
P D Hammen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SE7708942L publication Critical patent/SE7708942L/xx
Publication of SE435381B publication Critical patent/SE435381B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7708942A 1976-09-20 1977-08-05 Forfarande for framstellning av hypotensiva 2-(4-furoylpiperazin-1-yl)-4-amino-6,7-dimetoxikinazolin SE435381B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/724,707 US4062844A (en) 1976-09-20 1976-09-20 Process for preparing hypotensive 2-(4-aroylpiperazin-1-yl)-amino-6,7-dimethoxyquinazolines

Publications (2)

Publication Number Publication Date
SE7708942L SE7708942L (sv) 1978-03-21
SE435381B true SE435381B (sv) 1984-09-24

Family

ID=24911552

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7708942A SE435381B (sv) 1976-09-20 1977-08-05 Forfarande for framstellning av hypotensiva 2-(4-furoylpiperazin-1-yl)-4-amino-6,7-dimetoxikinazolin

Country Status (32)

Country Link
US (1) US4062844A (xx)
JP (1) JPS5337676A (xx)
AR (1) AR213659A1 (xx)
AT (1) AT357542B (xx)
AU (1) AU500908B2 (xx)
BE (1) BE858844A (xx)
BG (1) BG28054A3 (xx)
CA (1) CA1068699A (xx)
CH (1) CH632507A5 (xx)
CS (1) CS203172B2 (xx)
DD (1) DD132661A5 (xx)
DE (1) DE2740331C3 (xx)
DK (1) DK143340C (xx)
ES (1) ES462146A1 (xx)
FI (1) FI66610C (xx)
FR (1) FR2364918A1 (xx)
GB (1) GB1543668A (xx)
GR (1) GR69792B (xx)
HK (1) HK31181A (xx)
HU (1) HU180041B (xx)
IE (1) IE45966B1 (xx)
LU (1) LU78149A1 (xx)
MY (1) MY8100266A (xx)
NL (1) NL189132C (xx)
NO (1) NO147423C (xx)
PL (1) PL105830B1 (xx)
PT (1) PT67006B (xx)
RO (1) RO73051A (xx)
SE (1) SE435381B (xx)
SU (1) SU847919A3 (xx)
YU (1) YU39155B (xx)
ZA (1) ZA775098B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0022481A1 (en) * 1979-06-21 1981-01-21 Mitsubishi Yuka Pharmaceutical Co., Ltd. 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions
US4607034A (en) * 1979-10-29 1986-08-19 Mitsubishi Yuka Pharmaceutical Co., Ltd. Quinazoline derivatives and pharmaceutical composition thereof
JPS5793977A (en) * 1980-11-26 1982-06-11 Sankyo Co Ltd Acylaminoquinazoline derivative and its preparation
FI70411C (fi) * 1980-12-29 1986-09-19 Pfizer Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat
US4625012A (en) * 1985-08-26 1986-11-25 Essex Specialty Products, Inc. Moisture curable polyurethane polymers
IT1270993B (it) * 1994-03-18 1997-05-26 Recordati Chem Pharm Derivati chinzolilamminici attivi come alfa-antagonisti
GB9708917D0 (en) * 1997-05-01 1997-06-25 Pfizer Ltd Compounds useful in therapy
US6313294B1 (en) 1998-02-04 2001-11-06 Development Center For Biotechnology Process for preparing amides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3935213A (en) * 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives

Also Published As

Publication number Publication date
SU847919A3 (ru) 1981-07-15
YU39155B (en) 1984-06-30
BE858844A (fr) 1978-03-20
US4062844A (en) 1977-12-13
PT67006B (en) 1979-02-12
AU2822177A (en) 1979-03-01
DE2740331C3 (de) 1981-03-12
DE2740331B2 (de) 1980-06-19
ZA775098B (en) 1978-07-26
CA1068699A (en) 1979-12-25
RO73051A (ro) 1981-09-24
NL189132B (nl) 1992-08-17
FI772629A (fi) 1978-03-21
ATA636877A (de) 1979-12-15
ES462146A1 (es) 1978-06-16
DK395877A (da) 1978-03-21
CS203172B2 (en) 1981-02-27
DD132661A5 (de) 1978-10-18
AR213659A1 (es) 1979-02-28
NL189132C (nl) 1993-01-18
NL7709736A (nl) 1978-03-22
IE45966B1 (en) 1983-01-12
IE45966L (en) 1978-03-20
JPS5337676A (en) 1978-04-06
DK143340C (da) 1981-12-14
MY8100266A (en) 1981-12-31
PT67006A (en) 1977-10-01
SE7708942L (sv) 1978-03-21
GB1543668A (en) 1979-04-04
YU209677A (en) 1982-06-30
NO147423C (no) 1983-04-06
FI66610B (fi) 1984-07-31
GR69792B (xx) 1982-07-07
HK31181A (en) 1981-07-10
PL105830B1 (pl) 1979-11-30
AU500908B2 (en) 1979-06-07
NO773073L (no) 1978-03-21
NO147423B (no) 1982-12-27
AT357542B (de) 1980-07-10
BG28054A3 (en) 1980-02-25
FR2364918A1 (fr) 1978-04-14
HU180041B (en) 1983-01-28
DE2740331A1 (de) 1978-03-23
PL200710A1 (pl) 1978-05-22
LU78149A1 (fr) 1979-05-25
FR2364918B1 (xx) 1981-11-20
CH632507A5 (de) 1982-10-15
DK143340B (da) 1981-08-10
FI66610C (fi) 1984-11-12

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