ATA636877A - Verfahren zur herstellung von 2-(4-aroyl- piperazin-1-yl)-4-amino-6,7-dimethoxychina- zolinen - Google Patents

Verfahren zur herstellung von 2-(4-aroyl- piperazin-1-yl)-4-amino-6,7-dimethoxychina- zolinen

Info

Publication number
ATA636877A
ATA636877A AT636877A AT636877A ATA636877A AT A636877 A ATA636877 A AT A636877A AT 636877 A AT636877 A AT 636877A AT 636877 A AT636877 A AT 636877A AT A636877 A ATA636877 A AT A636877A
Authority
AT
Austria
Prior art keywords
dimethoxychina
zolines
aroyl
piperazin
amino
Prior art date
Application number
AT636877A
Other languages
English (en)
Other versions
AT357542B (de
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ATA636877A publication Critical patent/ATA636877A/de
Application granted granted Critical
Publication of AT357542B publication Critical patent/AT357542B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT636877A 1976-09-20 1977-09-05 Verfahren zur herstellung von 2-(4-aroyl- piperazin-1-yl)-4-amino-6,7-dimethoxychina- zolinen AT357542B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/724,707 US4062844A (en) 1976-09-20 1976-09-20 Process for preparing hypotensive 2-(4-aroylpiperazin-1-yl)-amino-6,7-dimethoxyquinazolines

Publications (2)

Publication Number Publication Date
ATA636877A true ATA636877A (de) 1979-12-15
AT357542B AT357542B (de) 1980-07-10

Family

ID=24911552

Family Applications (1)

Application Number Title Priority Date Filing Date
AT636877A AT357542B (de) 1976-09-20 1977-09-05 Verfahren zur herstellung von 2-(4-aroyl- piperazin-1-yl)-4-amino-6,7-dimethoxychina- zolinen

Country Status (32)

Country Link
US (1) US4062844A (de)
JP (1) JPS5337676A (de)
AR (1) AR213659A1 (de)
AT (1) AT357542B (de)
AU (1) AU500908B2 (de)
BE (1) BE858844A (de)
BG (1) BG28054A3 (de)
CA (1) CA1068699A (de)
CH (1) CH632507A5 (de)
CS (1) CS203172B2 (de)
DD (1) DD132661A5 (de)
DE (1) DE2740331C3 (de)
DK (1) DK143340C (de)
ES (1) ES462146A1 (de)
FI (1) FI66610C (de)
FR (1) FR2364918A1 (de)
GB (1) GB1543668A (de)
GR (1) GR69792B (de)
HK (1) HK31181A (de)
HU (1) HU180041B (de)
IE (1) IE45966B1 (de)
LU (1) LU78149A1 (de)
MY (1) MY8100266A (de)
NL (1) NL189132C (de)
NO (1) NO147423C (de)
PL (1) PL105830B1 (de)
PT (1) PT67006B (de)
RO (1) RO73051A (de)
SE (1) SE435381B (de)
SU (1) SU847919A3 (de)
YU (1) YU39155B (de)
ZA (1) ZA775098B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0022481A1 (de) * 1979-06-21 1981-01-21 Mitsubishi Yuka Pharmaceutical Co., Ltd. 5,6-Alkylenpyrimidin-Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen
US4607034A (en) * 1979-10-29 1986-08-19 Mitsubishi Yuka Pharmaceutical Co., Ltd. Quinazoline derivatives and pharmaceutical composition thereof
JPS5793977A (en) * 1980-11-26 1982-06-11 Sankyo Co Ltd Acylaminoquinazoline derivative and its preparation
FI70411C (fi) * 1980-12-29 1986-09-19 Pfizer Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat
US4625012A (en) * 1985-08-26 1986-11-25 Essex Specialty Products, Inc. Moisture curable polyurethane polymers
IT1270993B (it) * 1994-03-18 1997-05-26 Recordati Chem Pharm Derivati chinzolilamminici attivi come alfa-antagonisti
GB9708917D0 (en) * 1997-05-01 1997-06-25 Pfizer Ltd Compounds useful in therapy
US6313294B1 (en) 1998-02-04 2001-11-06 Development Center For Biotechnology Process for preparing amides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3935213A (en) * 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives

Also Published As

Publication number Publication date
PT67006A (en) 1977-10-01
BG28054A3 (en) 1980-02-25
DE2740331C3 (de) 1981-03-12
FR2364918B1 (de) 1981-11-20
PT67006B (en) 1979-02-12
IE45966B1 (en) 1983-01-12
AU2822177A (en) 1979-03-01
DK143340C (da) 1981-12-14
DK395877A (da) 1978-03-21
FR2364918A1 (fr) 1978-04-14
AU500908B2 (en) 1979-06-07
GB1543668A (en) 1979-04-04
HK31181A (en) 1981-07-10
FI772629A (fi) 1978-03-21
CH632507A5 (de) 1982-10-15
DE2740331A1 (de) 1978-03-23
FI66610C (fi) 1984-11-12
NL7709736A (nl) 1978-03-22
YU39155B (en) 1984-06-30
AT357542B (de) 1980-07-10
RO73051A (ro) 1981-09-24
LU78149A1 (fr) 1979-05-25
NO773073L (no) 1978-03-21
US4062844A (en) 1977-12-13
DK143340B (da) 1981-08-10
PL105830B1 (pl) 1979-11-30
SU847919A3 (ru) 1981-07-15
YU209677A (en) 1982-06-30
HU180041B (en) 1983-01-28
BE858844A (fr) 1978-03-20
PL200710A1 (pl) 1978-05-22
DD132661A5 (de) 1978-10-18
CS203172B2 (en) 1981-02-27
FI66610B (fi) 1984-07-31
MY8100266A (en) 1981-12-31
NO147423C (no) 1983-04-06
SE435381B (sv) 1984-09-24
CA1068699A (en) 1979-12-25
AR213659A1 (es) 1979-02-28
GR69792B (de) 1982-07-07
NL189132B (nl) 1992-08-17
ZA775098B (en) 1978-07-26
ES462146A1 (es) 1978-06-16
JPS5337676A (en) 1978-04-06
NO147423B (no) 1982-12-27
NL189132C (nl) 1993-01-18
DE2740331B2 (de) 1980-06-19
IE45966L (en) 1978-03-20
SE7708942L (sv) 1978-03-21

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee