SE429340B - 4-acetamidofenyl-1?721-(p-klorbensoyl)-2?721-metyl-5?721-metoxi-indol-3?721-yl-acetat och forfarande for dess framstellning - Google Patents
4-acetamidofenyl-1?721-(p-klorbensoyl)-2?721-metyl-5?721-metoxi-indol-3?721-yl-acetat och forfarande for dess framstellningInfo
- Publication number
- SE429340B SE429340B SE7806461A SE7806461A SE429340B SE 429340 B SE429340 B SE 429340B SE 7806461 A SE7806461 A SE 7806461A SE 7806461 A SE7806461 A SE 7806461A SE 429340 B SE429340 B SE 429340B
- Authority
- SE
- Sweden
- Prior art keywords
- formula
- para
- methyl
- compound
- methoxy
- Prior art date
Links
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- 238000000034 method Methods 0.000 title claims description 23
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- 230000009885 systemic effect Effects 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229960004906 thiomersal Drugs 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB23320/77A GB1587070A (en) | 1977-06-02 | 1977-06-02 | Pharmacologically-active 4-acetamidophenyl a-(2-methyl-ind(en/ol)-3-yl)-acetates processes for their preparation and pharmaceutical composition incorporating them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7806461L SE7806461L (sv) | 1979-02-09 |
| SE429340B true SE429340B (sv) | 1983-08-29 |
Family
ID=10193704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7806461A SE429340B (sv) | 1977-06-02 | 1978-06-01 | 4-acetamidofenyl-1?721-(p-klorbensoyl)-2?721-metyl-5?721-metoxi-indol-3?721-yl-acetat och forfarande for dess framstellning |
Country Status (13)
| Country | Link |
|---|---|
| AT (1) | AT364822B (de) |
| BE (1) | BE867760A (de) |
| CH (1) | CH644594A5 (de) |
| DE (1) | DE2824056A1 (de) |
| DK (1) | DK243978A (de) |
| FI (2) | FI781761A7 (de) |
| FR (1) | FR2392975A1 (de) |
| GB (1) | GB1587070A (de) |
| IE (1) | IE46916B1 (de) |
| LU (1) | LU79756A1 (de) |
| NL (1) | NL175818C (de) |
| NO (1) | NO149064C (de) |
| SE (1) | SE429340B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3269449D1 (en) * | 1981-11-02 | 1986-04-03 | Cermol Sa | P-acylaminophenol derivatives with a therapeutical effect, process for their preparation, and compositions with a therapeutical effect containing these derivatives as pharmacologically active ingredients |
| FR2835433B1 (fr) * | 2002-02-01 | 2006-02-17 | Richard Lab M | Utilisation de la 1-(-4-chlorobenzoyl)-5methoxy-2-methyl-1h- indole-3acetic 4-(acetylamino)phenylester pour la fabrication d'un medicament destine a inhiber exclusivement la cox2 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2234651C3 (de) * | 1972-07-14 | 1978-11-09 | Troponwerke Gmbh & Co Kg, 5000 Koeln | Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen |
-
1977
- 1977-06-02 GB GB23320/77A patent/GB1587070A/en not_active Expired
-
1978
- 1978-05-30 DE DE19782824056 patent/DE2824056A1/de not_active Withdrawn
- 1978-05-31 CH CH597878A patent/CH644594A5/de not_active IP Right Cessation
- 1978-06-01 NO NO781906A patent/NO149064C/no unknown
- 1978-06-01 NL NLAANVRAGE7805966,A patent/NL175818C/xx not_active IP Right Cessation
- 1978-06-01 IE IE1106/78A patent/IE46916B1/en unknown
- 1978-06-01 AT AT0398678A patent/AT364822B/de not_active IP Right Cessation
- 1978-06-01 DK DK243978A patent/DK243978A/da not_active Application Discontinuation
- 1978-06-01 SE SE7806461A patent/SE429340B/sv unknown
- 1978-06-02 FR FR7816638A patent/FR2392975A1/fr active Granted
- 1978-06-02 BE BE188276A patent/BE867760A/xx not_active IP Right Cessation
- 1978-06-02 FI FI781761A patent/FI781761A7/fi not_active Application Discontinuation
- 1978-06-02 LU LU79756A patent/LU79756A1/xx unknown
- 1978-06-02 FI FI781760A patent/FI781760A7/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATA398678A (de) | 1981-04-15 |
| NO149064C (no) | 1984-02-22 |
| SE7806461L (sv) | 1979-02-09 |
| FR2392975B1 (de) | 1982-12-31 |
| IE781106L (en) | 1978-12-02 |
| NO149064B (no) | 1983-10-31 |
| GB1587070A (en) | 1981-03-25 |
| NL175818C (nl) | 1985-01-02 |
| NL7805966A (nl) | 1978-12-05 |
| BE867760A (fr) | 1978-10-02 |
| NL175818B (nl) | 1984-08-01 |
| DK243978A (da) | 1978-12-03 |
| LU79756A1 (fr) | 1978-11-28 |
| FI781761A7 (fi) | 1978-12-03 |
| FI781760A7 (fi) | 1978-12-03 |
| NO781906L (no) | 1978-12-05 |
| AT364822B (de) | 1981-11-25 |
| IE46916B1 (en) | 1983-11-02 |
| CH644594A5 (en) | 1984-08-15 |
| DE2824056A1 (de) | 1978-12-14 |
| FR2392975A1 (fr) | 1978-12-29 |
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