IE781106L - 4-acetamidophenyl ó-(2-methyl-ind (en/ol)-3-yl)-acetates. - Google Patents

4-acetamidophenyl ó-(2-methyl-ind (en/ol)-3-yl)-acetates.

Info

Publication number
IE781106L
IE781106L IE781106A IE110678A IE781106L IE 781106 L IE781106 L IE 781106L IE 781106 A IE781106 A IE 781106A IE 110678 A IE110678 A IE 110678A IE 781106 L IE781106 L IE 781106L
Authority
IE
Ireland
Prior art keywords
denotes
bond
acetamidophenyl
ind
acetates
Prior art date
Application number
IE781106A
Other versions
IE46916B1 (en
Original Assignee
Sterwin Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterwin Ag filed Critical Sterwin Ag
Publication of IE781106L publication Critical patent/IE781106L/en
Publication of IE46916B1 publication Critical patent/IE46916B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The 4-acetamidophenyl alpha -(2-methyl-ind-[en/ol]-3-yl)acetates of the general formula III <IMAGE> in which A denotes a <3bL>C.Cl, <3bL>N, <3bL>C.H or <3bL>C.SO.CH3 group, R denotes a fluorine atom or a methoxy group, n denotes 0 or 1, and either X denotes a nitrogen atom and Y denotes a -CO- bond or X denotes a carbon atom and Y denotes a =CH bond and the broken line denotes a second C-C bond are novel compounds which are anti-inflammatory analgesics and/or have an analgesic action. The compounds are particularly useful since they cause practically no unwanted side effects on the digestive tract. [GB1587070A]
IE1106/78A 1977-06-02 1978-06-01 New pharmacologically-active 4-acetamidophenyl -(2-methyl-ind(en/ol)-3-yl)-acetates, process for their preparation, and pharmaceutical compositions incorporating them IE46916B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB23320/77A GB1587070A (en) 1977-06-02 1977-06-02 Pharmacologically-active 4-acetamidophenyl a-(2-methyl-ind(en/ol)-3-yl)-acetates processes for their preparation and pharmaceutical composition incorporating them

Publications (2)

Publication Number Publication Date
IE781106L true IE781106L (en) 1978-12-02
IE46916B1 IE46916B1 (en) 1983-11-02

Family

ID=10193704

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1106/78A IE46916B1 (en) 1977-06-02 1978-06-01 New pharmacologically-active 4-acetamidophenyl -(2-methyl-ind(en/ol)-3-yl)-acetates, process for their preparation, and pharmaceutical compositions incorporating them

Country Status (13)

Country Link
AT (1) AT364822B (en)
BE (1) BE867760A (en)
CH (1) CH644594A5 (en)
DE (1) DE2824056A1 (en)
DK (1) DK243978A (en)
FI (2) FI781760A (en)
FR (1) FR2392975A1 (en)
GB (1) GB1587070A (en)
IE (1) IE46916B1 (en)
LU (1) LU79756A1 (en)
NL (1) NL175818C (en)
NO (1) NO149064C (en)
SE (1) SE429340B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078765B1 (en) * 1981-11-02 1986-02-26 Cermol S.A. P-acylaminophenol derivatives with a therapeutical effect, process for their preparation, and compositions with a therapeutical effect containing these derivatives as pharmacologically active ingredients
FR2835433B1 (en) * 2002-02-01 2006-02-17 Richard Lab M USE OF 1- (4-CHLOROBENZOYL) -5-METHHOXY-2-METHYL-1H-INDOLE-3ACETIC 4- (ACETYLAMINO) PHENYL ESTER FOR THE PRODUCTION OF A MEDICAMENT FOR INHIBITING COX2 EXCLUSIVELY

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2234651C3 (en) * 1972-07-14 1978-11-09 Troponwerke Gmbh & Co Kg, 5000 Koeln Square brackets on l- (p-chlorobenzoyl) -5-methoxy-2-methyl-3-indole] -acetoxj acetic acid, its salts with bases, processes for their production and pharmacological preparations

Also Published As

Publication number Publication date
CH644594A5 (en) 1984-08-15
FR2392975B1 (en) 1982-12-31
NL7805966A (en) 1978-12-05
FR2392975A1 (en) 1978-12-29
DE2824056A1 (en) 1978-12-14
NL175818B (en) 1984-08-01
DK243978A (en) 1978-12-03
SE429340B (en) 1983-08-29
BE867760A (en) 1978-10-02
NO149064C (en) 1984-02-22
SE7806461L (en) 1979-02-09
GB1587070A (en) 1981-03-25
ATA398678A (en) 1981-04-15
LU79756A1 (en) 1978-11-28
IE46916B1 (en) 1983-11-02
FI781761A (en) 1978-12-03
AT364822B (en) 1981-11-25
NL175818C (en) 1985-01-02
NO781906L (en) 1978-12-05
FI781760A (en) 1978-12-03
NO149064B (en) 1983-10-31

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