AT364822B - Verfahren zur herstellung von neuen 4acetamidophenyl-alpha-(2-methyl-ind(en/ol)-3-yl)-acetaten und deren saeureadditionssalzen - Google Patents
Verfahren zur herstellung von neuen 4acetamidophenyl-alpha-(2-methyl-ind(en/ol)-3-yl)-acetaten und deren saeureadditionssalzenInfo
- Publication number
- AT364822B AT364822B AT0398678A AT398678A AT364822B AT 364822 B AT364822 B AT 364822B AT 0398678 A AT0398678 A AT 0398678A AT 398678 A AT398678 A AT 398678A AT 364822 B AT364822 B AT 364822B
- Authority
- AT
- Austria
- Prior art keywords
- ind
- acetates
- alpha
- methyl
- acid addition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB23320/77A GB1587070A (en) | 1977-06-02 | 1977-06-02 | Pharmacologically-active 4-acetamidophenyl a-(2-methyl-ind(en/ol)-3-yl)-acetates processes for their preparation and pharmaceutical composition incorporating them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA398678A ATA398678A (de) | 1981-04-15 |
| AT364822B true AT364822B (de) | 1981-11-25 |
Family
ID=10193704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0398678A AT364822B (de) | 1977-06-02 | 1978-06-01 | Verfahren zur herstellung von neuen 4acetamidophenyl-alpha-(2-methyl-ind(en/ol)-3-yl)-acetaten und deren saeureadditionssalzen |
Country Status (13)
| Country | Link |
|---|---|
| AT (1) | AT364822B (de) |
| BE (1) | BE867760A (de) |
| CH (1) | CH644594A5 (de) |
| DE (1) | DE2824056A1 (de) |
| DK (1) | DK243978A (de) |
| FI (2) | FI781760A (de) |
| FR (1) | FR2392975A1 (de) |
| GB (1) | GB1587070A (de) |
| IE (1) | IE46916B1 (de) |
| LU (1) | LU79756A1 (de) |
| NL (1) | NL175818C (de) |
| NO (1) | NO149064C (de) |
| SE (1) | SE429340B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0078765B1 (de) * | 1981-11-02 | 1986-02-26 | Cermol S.A. | P-Acylamino-Phenol-Derivate mit therapeutischem Effekt, Verfahren zu deren Herstellung und Zusammensetzung mit therapeutischem Effekt, diese Derivate als pharmakologische aktive Ingredienzen enthaltend |
| FR2835433B1 (fr) * | 2002-02-01 | 2006-02-17 | Richard Lab M | Utilisation de la 1-(-4-chlorobenzoyl)-5methoxy-2-methyl-1h- indole-3acetic 4-(acetylamino)phenylester pour la fabrication d'un medicament destine a inhiber exclusivement la cox2 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2234651C3 (de) * | 1972-07-14 | 1978-11-09 | Troponwerke Gmbh & Co Kg, 5000 Koeln | Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen |
-
1977
- 1977-06-02 GB GB23320/77A patent/GB1587070A/en not_active Expired
-
1978
- 1978-05-30 DE DE19782824056 patent/DE2824056A1/de not_active Withdrawn
- 1978-05-31 CH CH597878A patent/CH644594A5/de not_active IP Right Cessation
- 1978-06-01 SE SE7806461A patent/SE429340B/sv unknown
- 1978-06-01 DK DK243978A patent/DK243978A/da not_active Application Discontinuation
- 1978-06-01 NL NLAANVRAGE7805966,A patent/NL175818C/xx not_active IP Right Cessation
- 1978-06-01 AT AT0398678A patent/AT364822B/de not_active IP Right Cessation
- 1978-06-01 IE IE1106/78A patent/IE46916B1/en unknown
- 1978-06-01 NO NO781906A patent/NO149064C/no unknown
- 1978-06-02 LU LU79756A patent/LU79756A1/xx unknown
- 1978-06-02 FR FR7816638A patent/FR2392975A1/fr active Granted
- 1978-06-02 FI FI781760A patent/FI781760A/fi not_active Application Discontinuation
- 1978-06-02 BE BE188276A patent/BE867760A/xx not_active IP Right Cessation
- 1978-06-02 FI FI781761A patent/FI781761A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CH644594A5 (en) | 1984-08-15 |
| FR2392975B1 (de) | 1982-12-31 |
| NL7805966A (nl) | 1978-12-05 |
| FR2392975A1 (fr) | 1978-12-29 |
| DE2824056A1 (de) | 1978-12-14 |
| NL175818B (nl) | 1984-08-01 |
| DK243978A (da) | 1978-12-03 |
| SE429340B (sv) | 1983-08-29 |
| BE867760A (fr) | 1978-10-02 |
| NO149064C (no) | 1984-02-22 |
| SE7806461L (sv) | 1979-02-09 |
| GB1587070A (en) | 1981-03-25 |
| ATA398678A (de) | 1981-04-15 |
| LU79756A1 (fr) | 1978-11-28 |
| IE46916B1 (en) | 1983-11-02 |
| FI781761A (fi) | 1978-12-03 |
| NL175818C (nl) | 1985-01-02 |
| NO781906L (no) | 1978-12-05 |
| FI781760A (fi) | 1978-12-03 |
| NO149064B (no) | 1983-10-31 |
| IE781106L (en) | 1978-12-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| EIH | Change in the person of patent owner |