SE428014B - Analogiforfarande for framstellning av n?722-substituerade l-argininderivat - Google Patents
Analogiforfarande for framstellning av n?722-substituerade l-argininderivatInfo
- Publication number
- SE428014B SE428014B SE7608791A SE7608791A SE428014B SE 428014 B SE428014 B SE 428014B SE 7608791 A SE7608791 A SE 7608791A SE 7608791 A SE7608791 A SE 7608791A SE 428014 B SE428014 B SE 428014B
- Authority
- SE
- Sweden
- Prior art keywords
- formula
- substituted
- argin
- ingredients
- preparing
- Prior art date
Links
- 239000004615 ingredient Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002059 L-arginyl group Chemical class O=C([*])[C@](N([H])[H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H] 0.000 abstract 1
- 229940122388 Thrombin inhibitor Drugs 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- -1 thionyl halide Chemical class 0.000 abstract 1
- 239000003868 thrombin inhibitor Substances 0.000 abstract 1
- 230000003558 thrombophilic effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/24—[b,e]-condensed with two six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Peptides Or Proteins (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9641775A JPS5941991B2 (ja) | 1975-08-08 | 1975-08-08 | Ｎ↑２−置換アルギニンアミド類またはその酸付加塩の製造法 |
| JP50106139A JPS5913500B2 (ja) | 1975-09-02 | 1975-09-02 | Ｎ↑２−ナフタレンスルホニルアルギニンアミド類またはその酸付加塩の製造法 |
| JP50110242A JPS5913501B2 (ja) | 1975-09-11 | 1975-09-11 | Ｎ↑２−ナフタレンスルホニルアルギニンアミド類またはその酸付加塩の製造法 |
| JP11852575A JPS5913503B2 (ja) | 1975-10-01 | 1975-10-01 | Ｎ↑２−ナフタレンスルホニルアルギニンエステルもしくはアミド類またはそれらの酸付加塩の製造法 |
| JP12117375A JPS5822030B2 (ja) | 1975-10-07 | 1975-10-07 | Ｎ２− ナフタレンスルホニルアルギニンエステルルイ マタハ ソノサンフカエンノセイゾウホウ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7608791L SE7608791L (sv) | 1977-02-09 |
| SE428014B true SE428014B (sv) | 1983-05-30 |
Family
ID=27525790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7608791A SE428014B (sv) | 1975-08-08 | 1976-08-25 | Analogiforfarande for framstellning av n?722-substituerade l-argininderivat |
Country Status (9)
| Country | Link |
|---|---|
| CA (1) | CA1106851A (enrdf_load_stackoverflow) |
| CH (3) | CH632243A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2635548C2 (enrdf_load_stackoverflow) |
| DK (1) | DK357876A (enrdf_load_stackoverflow) |
| FR (1) | FR2320088A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1530667A (enrdf_load_stackoverflow) |
| NL (1) | NL7608784A (enrdf_load_stackoverflow) |
| NO (1) | NO762744L (enrdf_load_stackoverflow) |
| SE (1) | SE428014B (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9504350D0 (en) * | 1995-03-04 | 1995-04-26 | Sod Conseils Rech Applic | Arginine derivatives |
-
1976
- 1976-07-19 CA CA257,283A patent/CA1106851A/en not_active Expired
- 1976-08-04 CH CH996676A patent/CH632243A5/de not_active IP Right Cessation
- 1976-08-06 DE DE2635548A patent/DE2635548C2/de not_active Expired
- 1976-08-06 GB GB32910/76A patent/GB1530667A/en not_active Expired
- 1976-08-06 DK DK357876A patent/DK357876A/da not_active Application Discontinuation
- 1976-08-06 NO NO762744A patent/NO762744L/no unknown
- 1976-08-06 NL NL7608784A patent/NL7608784A/xx not_active Application Discontinuation
- 1976-08-09 FR FR7624336A patent/FR2320088A1/fr active Granted
- 1976-08-25 SE SE7608791A patent/SE428014B/xx not_active IP Right Cessation
-
1981
- 1981-06-10 CH CH379781A patent/CH628880A5/de not_active IP Right Cessation
- 1981-06-10 CH CH379881A patent/CH629764A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SE7608791L (sv) | 1977-02-09 |
| CH629764A5 (en) | 1982-05-14 |
| FR2320088A1 (fr) | 1977-03-04 |
| DK357876A (da) | 1977-02-09 |
| GB1530667A (en) | 1978-11-01 |
| DE2635548A1 (de) | 1977-03-03 |
| FR2320088B1 (enrdf_load_stackoverflow) | 1978-12-22 |
| NO762744L (enrdf_load_stackoverflow) | 1977-02-09 |
| DE2635548C2 (de) | 1985-05-23 |
| CH632243A5 (en) | 1982-09-30 |
| CA1106851A (en) | 1981-08-11 |
| NL7608784A (nl) | 1977-02-10 |
| CH628880A5 (en) | 1982-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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