FR2320088A1 - Derives de l'arginine, leur preparation et leurs utilisations therapeutiques - Google Patents

Derives de l'arginine, leur preparation et leurs utilisations therapeutiques

Info

Publication number
FR2320088A1
FR2320088A1 FR7624336A FR7624336A FR2320088A1 FR 2320088 A1 FR2320088 A1 FR 2320088A1 FR 7624336 A FR7624336 A FR 7624336A FR 7624336 A FR7624336 A FR 7624336A FR 2320088 A1 FR2320088 A1 FR 2320088A1
Authority
FR
France
Prior art keywords
preparation
therapeutic uses
arginine derivatives
arginine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7624336A
Other languages
English (en)
French (fr)
Other versions
FR2320088B1 (enrdf_load_stackoverflow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Chemical Corp
Original Assignee
Mitsubishi Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9641775A external-priority patent/JPS5941991B2/ja
Priority claimed from JP50106139A external-priority patent/JPS5913500B2/ja
Priority claimed from JP50110242A external-priority patent/JPS5913501B2/ja
Priority claimed from JP11852575A external-priority patent/JPS5913503B2/ja
Priority claimed from JP12117375A external-priority patent/JPS5822030B2/ja
Application filed by Mitsubishi Chemical Industries Ltd filed Critical Mitsubishi Chemical Industries Ltd
Publication of FR2320088A1 publication Critical patent/FR2320088A1/fr
Application granted granted Critical
Publication of FR2320088B1 publication Critical patent/FR2320088B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/24—[b,e]-condensed with two six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7624336A 1975-08-08 1976-08-09 Derives de l'arginine, leur preparation et leurs utilisations therapeutiques Granted FR2320088A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP9641775A JPS5941991B2 (ja) 1975-08-08 1975-08-08 Ｎ↑２−置換アルギニンアミド類またはその酸付加塩の製造法
JP50106139A JPS5913500B2 (ja) 1975-09-02 1975-09-02 Ｎ↑２−ナフタレンスルホニルアルギニンアミド類またはその酸付加塩の製造法
JP50110242A JPS5913501B2 (ja) 1975-09-11 1975-09-11 Ｎ↑２−ナフタレンスルホニルアルギニンアミド類またはその酸付加塩の製造法
JP11852575A JPS5913503B2 (ja) 1975-10-01 1975-10-01 Ｎ↑２−ナフタレンスルホニルアルギニンエステルもしくはアミド類またはそれらの酸付加塩の製造法
JP12117375A JPS5822030B2 (ja) 1975-10-07 1975-10-07 Ｎ２− ナフタレンスルホニルアルギニンエステルルイ マタハ ソノサンフカエンノセイゾウホウ

Publications (2)

Publication Number Publication Date
FR2320088A1 true FR2320088A1 (fr) 1977-03-04
FR2320088B1 FR2320088B1 (enrdf_load_stackoverflow) 1978-12-22

Family

ID=27525790

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7624336A Granted FR2320088A1 (fr) 1975-08-08 1976-08-09 Derives de l'arginine, leur preparation et leurs utilisations therapeutiques

Country Status (9)

Country Link
CA (1) CA1106851A (enrdf_load_stackoverflow)
CH (3) CH632243A5 (enrdf_load_stackoverflow)
DE (1) DE2635548C2 (enrdf_load_stackoverflow)
DK (1) DK357876A (enrdf_load_stackoverflow)
FR (1) FR2320088A1 (enrdf_load_stackoverflow)
GB (1) GB1530667A (enrdf_load_stackoverflow)
NL (1) NL7608784A (enrdf_load_stackoverflow)
NO (1) NO762744L (enrdf_load_stackoverflow)
SE (1) SE428014B (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972940A (en) * 1995-03-04 1999-10-26 Societe De Conseils Recherches Et D'applications Scientifiques (S.C.R.A.S.) Arginine analogues having nitric oxide synthase inhibitor activity

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972940A (en) * 1995-03-04 1999-10-26 Societe De Conseils Recherches Et D'applications Scientifiques (S.C.R.A.S.) Arginine analogues having nitric oxide synthase inhibitor activity
RU2168493C2 (ru) * 1995-03-04 2001-06-10 Сосьете де Консей де Решерш э Д'Аппликасьон Сьентифик (С.К.Р.А.С) Производные l-аргинина, способ их получения, фармацевтическая композиция, обладающая ингибирующей no-синтазу активностью

Also Published As

Publication number Publication date
SE7608791L (sv) 1977-02-09
SE428014B (sv) 1983-05-30
CH629764A5 (en) 1982-05-14
DK357876A (da) 1977-02-09
GB1530667A (en) 1978-11-01
DE2635548A1 (de) 1977-03-03
FR2320088B1 (enrdf_load_stackoverflow) 1978-12-22
NO762744L (enrdf_load_stackoverflow) 1977-02-09
DE2635548C2 (de) 1985-05-23
CH632243A5 (en) 1982-09-30
CA1106851A (en) 1981-08-11
NL7608784A (nl) 1977-02-10
CH628880A5 (en) 1982-03-31

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Legal Events

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ST Notification of lapse