SE416472B - Forfarande for framstellning av 7-(alfa-amino-p-hydroxifenylacetamido)-3-(1,2,3-triazolyltiometyl)-3-cefem-4-karboxylsyror - Google Patents

Forfarande for framstellning av 7-(alfa-amino-p-hydroxifenylacetamido)-3-(1,2,3-triazolyltiometyl)-3-cefem-4-karboxylsyror

Info

Publication number
SE416472B
SE416472B SE7302579A SE7302579A SE416472B SE 416472 B SE416472 B SE 416472B SE 7302579 A SE7302579 A SE 7302579A SE 7302579 A SE7302579 A SE 7302579A SE 416472 B SE416472 B SE 416472B
Authority
SE
Sweden
Prior art keywords
amino
methyl
acid
compound
preparation
Prior art date
Application number
SE7302579A
Other languages
English (en)
Swedish (sv)
Inventor
G L Dunn
J R E Hoover
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US262903A external-priority patent/US3867380A/en
Priority claimed from US00289499A external-priority patent/US3855213A/en
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of SE416472B publication Critical patent/SE416472B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7302579A 1972-06-14 1973-02-23 Forfarande for framstellning av 7-(alfa-amino-p-hydroxifenylacetamido)-3-(1,2,3-triazolyltiometyl)-3-cefem-4-karboxylsyror SE416472B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US262903A US3867380A (en) 1971-02-18 1972-06-14 3-Heterocyclic thiomethylcephalosporins
US00289499A US3855213A (en) 1971-02-18 1972-09-15 3-heterocyclic thiomethyl-cephalosporins

Publications (1)

Publication Number Publication Date
SE416472B true SE416472B (sv) 1981-01-05

Family

ID=26949532

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7302579A SE416472B (sv) 1972-06-14 1973-02-23 Forfarande for framstellning av 7-(alfa-amino-p-hydroxifenylacetamido)-3-(1,2,3-triazolyltiometyl)-3-cefem-4-karboxylsyror
SE7304545A SE404190B (sv) 1972-06-14 1973-03-30 Forfarande for framstellning av 7 (alfa-amino-p-hydroxifenylacetamido)-3-(1-metyl-5-tetrazolyltiometyl)-3-cefem-karboxylsyra och 7 (alfa-amino-p-hydroxifenylacetamido)-3-(5-metyl-1,3,4-tiadiazol-2-yltiometyl)-3-cefem...

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7304545A SE404190B (sv) 1972-06-14 1973-03-30 Forfarande for framstellning av 7 (alfa-amino-p-hydroxifenylacetamido)-3-(1-metyl-5-tetrazolyltiometyl)-3-cefem-karboxylsyra och 7 (alfa-amino-p-hydroxifenylacetamido)-3-(5-metyl-1,3,4-tiadiazol-2-yltiometyl)-3-cefem...

Country Status (20)

Country Link
JP (2) JPS5518716B2 (hr)
AR (1) AR197237A1 (hr)
AT (1) AT324560B (hr)
AU (1) AU464107B2 (hr)
CA (2) CA1076560A (hr)
CH (2) CH589093A5 (hr)
DD (1) DD105238A5 (hr)
DE (1) DE2316867C2 (hr)
DK (1) DK142913B (hr)
ES (2) ES412207A1 (hr)
FI (1) FI56843C (hr)
FR (2) FR2187298B1 (hr)
GB (2) GB1363833A (hr)
HU (1) HU168689B (hr)
IE (2) IE37409B1 (hr)
IL (1) IL42126A (hr)
NL (2) NL7302817A (hr)
PH (1) PH9941A (hr)
PL (1) PL91074B1 (hr)
SE (2) SE416472B (hr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR780000197B1 (en) * 1972-12-26 1978-05-26 Bristol Myers Co Method for preparing antibacterial agent
FR2215942B1 (hr) * 1973-01-31 1978-12-22 Bristol Myers Co
GB1476981A (en) * 1974-06-05 1977-06-16 Bristol Myers Co Substituted penicillanic acids
CA1074784A (en) * 1974-09-06 1980-04-01 Sumitomo Chemical Company N-ACYLAMINO-.alpha.-ARYLACETAMIDO CEPHALOSPORINS
JPS5346995A (en) * 1976-10-12 1978-04-27 Sangyo Kagaku Kenkyu Kyokai Antibacterial agents
NL162387C (nl) * 1977-09-06 1980-05-16 Gist Brocades Nv Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
JPS6010226U (ja) * 1983-06-30 1985-01-24 松下電工株式会社 昇降装置
JPS6182606A (ja) * 1984-09-29 1986-04-26 東芝ライテック株式会社 昇降装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA698494B (en) * 1969-02-26 1971-07-28 Lilly Co Eli Sulfur-containing cephalosporing antibiotics
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds

Also Published As

Publication number Publication date
CA999293A (en) 1976-11-02
IE37499B1 (en) 1977-08-03
ES412207A1 (es) 1976-01-01
IL42126A0 (en) 1973-06-29
FR2187298B1 (hr) 1976-12-03
DE2316867A1 (de) 1974-01-03
GB1363833A (en) 1974-08-21
FR2187299A1 (hr) 1974-01-18
IE37409B1 (en) 1977-07-20
IE37409L (en) 1973-12-14
DE2316866B2 (de) 1976-10-07
AR197237A1 (es) 1974-03-22
JPS5953274B2 (ja) 1984-12-24
DE2316866A1 (de) 1974-01-03
DK142913C (hr) 1981-09-28
SE404190B (sv) 1978-09-25
ES413501A1 (es) 1976-07-16
HU168689B (hr) 1976-06-28
NL7305206A (hr) 1973-12-18
JPS5518716B2 (hr) 1980-05-21
JPS4954393A (hr) 1974-05-27
FR2187299B1 (hr) 1976-12-03
FI56843B (fi) 1979-12-31
AT324560B (de) 1975-09-10
CH586709A5 (hr) 1977-04-15
GB1358027A (en) 1974-06-26
CA1076560A (en) 1980-04-29
NL7302817A (hr) 1973-12-18
FI56843C (fi) 1980-04-10
AU5234573A (en) 1974-08-22
IE37499L (en) 1973-12-14
DK142913B (da) 1981-02-23
FR2187298A1 (hr) 1974-01-18
AU464107B2 (en) 1975-08-14
DD105238A5 (hr) 1974-04-12
CH589093A5 (hr) 1977-06-30
JPS4931689A (hr) 1974-03-22
PL91074B1 (en) 1977-02-28
DE2316867C2 (de) 1982-05-19
IL42126A (en) 1975-12-31
PH9941A (en) 1976-06-14

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