SE405598B - Forfarande for framstellning av nya terapeutiskt verksamma derivat av 4-(3-amino-2-hydroxi-propoxi)-indol - Google Patents

Forfarande for framstellning av nya terapeutiskt verksamma derivat av 4-(3-amino-2-hydroxi-propoxi)-indol

Info

Publication number
SE405598B
SE405598B SE7512823A SE7512823A SE405598B SE 405598 B SE405598 B SE 405598B SE 7512823 A SE7512823 A SE 7512823A SE 7512823 A SE7512823 A SE 7512823A SE 405598 B SE405598 B SE 405598B
Authority
SE
Sweden
Prior art keywords
propoxi
hydroxi
indol
derivatives
amino
Prior art date
Application number
SE7512823A
Other languages
English (en)
Swedish (sv)
Other versions
SE7512823L (sv
Inventor
W Kampe
K Stach
M Thiel
W Bartsch
K Dietmann
E Roesch
W Schaumann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742454406 external-priority patent/DE2454406A1/de
Priority claimed from DE19752505681 external-priority patent/DE2505681A1/de
Priority claimed from DE19752508251 external-priority patent/DE2508251C2/de
Priority claimed from DE19752528771 external-priority patent/DE2528771A1/de
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of SE7512823L publication Critical patent/SE7512823L/xx
Publication of SE405598B publication Critical patent/SE405598B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
SE7512823A 1974-11-16 1975-11-14 Forfarande for framstellning av nya terapeutiskt verksamma derivat av 4-(3-amino-2-hydroxi-propoxi)-indol SE405598B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19742454406 DE2454406A1 (de) 1974-11-16 1974-11-16 Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE19752505681 DE2505681A1 (de) 1975-02-11 1975-02-11 Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE19752508251 DE2508251C2 (de) 1975-02-26 1975-02-26 Derivate des Indols, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel
DE19752528771 DE2528771A1 (de) 1975-06-27 1975-06-27 Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
SE7512823L SE7512823L (sv) 1976-05-17
SE405598B true SE405598B (sv) 1978-12-18

Family

ID=27431915

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7512823A SE405598B (sv) 1974-11-16 1975-11-14 Forfarande for framstellning av nya terapeutiskt verksamma derivat av 4-(3-amino-2-hydroxi-propoxi)-indol

Country Status (21)

Country Link
US (2) US4076829A (xx)
JP (1) JPS5845423B2 (xx)
AR (3) AR208570A1 (xx)
AT (1) AT349004B (xx)
AU (1) AU473145B2 (xx)
CA (1) CA1051002A (xx)
CH (3) CH622248A5 (xx)
CS (1) CS199604B2 (xx)
DD (1) DD123460A5 (xx)
DK (1) DK140985C (xx)
ES (1) ES442648A1 (xx)
FI (1) FI61693C (xx)
FR (1) FR2290897A1 (xx)
GB (1) GB1471636A (xx)
HU (1) HU173308B (xx)
IE (1) IE42286B1 (xx)
LU (1) LU73808A1 (xx)
NL (1) NL7513336A (xx)
PL (1) PL100799B1 (xx)
SE (1) SE405598B (xx)
SU (2) SU649314A3 (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4314943A (en) * 1977-07-13 1982-02-09 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
DE2830211A1 (de) * 1977-07-21 1979-02-01 Sandoz Ag Substituierte indol-derivate, ihre herstellung und verwendung
WO1980000152A1 (en) * 1978-07-03 1980-02-07 Sandoz Ag 3-aminopropoxy-aryl derivates,preparation and use thereof
US4495352A (en) * 1979-02-13 1985-01-22 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
DE3068678D1 (en) * 1979-08-10 1984-08-30 Sandoz Ag 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
DE3030047A1 (de) * 1980-08-08 1982-03-11 Boehringer Mannheim Gmbh, 6800 Mannheim Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3115993A1 (de) * 1981-04-13 1982-11-11 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue indol-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die diese verbindungen enthalten
US5013732A (en) * 1984-08-06 1991-05-07 Sterling Drug Inc. 3-arylcarbonyl- and 3-cycloalkyl-carbonyl-1-aminoalkyl-1H-indoles
US5013761A (en) * 1988-06-03 1991-05-07 Eli Lilly And Company Serotonin antagonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3471515A (en) * 1965-02-01 1969-10-07 Sandoz Ag (2-hydroxy-3-substituted aminopropoxy)indoles
CH475981A (de) * 1966-12-13 1969-07-31 Sandoz Ag Verfahren zur Herstellung neuer Indol-Derivate
GB1308029A (en) * 1969-07-25 1973-02-21 Sandoz Ltd Indole derivatives
BE754360A (fr) * 1969-08-05 1971-02-03 Sandoz Sa Nouveaux derives de l'indole, leur preparation et medicaments contenantdes derives
US3705907A (en) * 1970-02-19 1972-12-12 Sandoz Ltd 4-(2-hydroxy)-3-aminopropoxy)-indole derivatives
US3699123A (en) * 1970-03-24 1972-10-17 Sandoz Ltd 4-(3-amino-2-hydroxy-propoxy) indole derivatives
US3751429A (en) * 1970-03-24 1973-08-07 Sandoz Ltd 4-(3-amino-2-substituted propoxy)indole derivatives
CH535762A (de) * 1970-09-30 1973-04-15 Sandoz Ag Verfahren zur Herstellung neuer Indolderivate
CH540253A (de) * 1971-01-07 1973-08-15 Sandoz Ag Verfahren zur Herstellung neuer Indole

Also Published As

Publication number Publication date
CH622248A5 (xx) 1981-03-31
ES442648A1 (es) 1977-04-16
HU173308B (hu) 1979-04-28
SU649314A3 (ru) 1979-02-25
DK140985B (da) 1979-12-17
GB1471636A (en) 1977-04-27
PL100799B1 (pl) 1978-11-30
IE42286L (en) 1976-05-16
LU73808A1 (xx) 1976-06-11
JPS5845423B2 (ja) 1983-10-08
CH623308A5 (xx) 1981-05-29
AU473145B2 (en) 1976-06-17
SU679135A3 (ru) 1979-08-05
FR2290897B1 (xx) 1978-11-10
AU8669275A (en) 1976-06-17
FI61693B (fi) 1982-05-31
FI753219A (xx) 1976-05-17
IE42286B1 (en) 1980-07-16
CA1051002A (en) 1979-03-20
AR213287A1 (es) 1979-01-15
DK513575A (da) 1976-05-17
SE7512823L (sv) 1976-05-17
DK140985C (da) 1980-06-02
ATA870975A (de) 1978-08-15
FR2290897A1 (fr) 1976-06-11
US4229464A (en) 1980-10-21
NL7513336A (nl) 1976-05-18
AR208570A1 (es) 1977-02-15
JPS5175059A (xx) 1976-06-29
CH623307A5 (xx) 1981-05-29
FI61693C (fi) 1982-09-10
US4076829A (en) 1978-02-28
AT349004B (de) 1979-03-12
AR211268A1 (es) 1977-11-15
DD123460A5 (xx) 1976-12-20
CS199604B2 (en) 1980-07-31

Similar Documents

Publication Publication Date Title
SE430329B (sv) Forfarande for framstellning av nya terapeutiskt verksamma foreningar
SE7513571L (sv) Forfarande for framstellning av nya substituerade pyridiner
SE7807571L (sv) Forfarande for framstellning av antigraviditetsvaccin
SE431548B (sv) Forfarande for framstellning av nya cefalosporinderivat
SE405598B (sv) Forfarande for framstellning av nya terapeutiskt verksamma derivat av 4-(3-amino-2-hydroxi-propoxi)-indol
SE409452B (sv) Forfarande for framstellning av stilbenderivat
SE7506237L (sv) Forfarande for framstellning av dekahydroisokinolinderivat
SE421212B (sv) Forfarande for framstellning av nya derivat av daunorubicin
SE419646B (sv) Forfarande for framstellning av 8-halogen-dibensofuran-3-ettiksyra-derivat
SE432763B (sv) Forfarande for framstellning av nya homoftalimider
SE382980B (sv) Forfarande for framstellning av nya derivat av hexahydrofenantridin
SE421315B (sv) Forfarande for framstellning av vinkamin och derivat derav
SE7800681L (sv) Forfarande for framstellning av nya derivat av isokinolin
SE7507648L (sv) Forfarande for framstellning av basiskt substituerade derivat av 4-hydroxi-bensimidazol
SE439159B (sv) Forfarnde for framstellning av nya 5-fluoropyrimidin-4-on-derivat
SE7513739L (sv) Forfarande for framstellning av 2-scyl-4-oxo-pyrazino-isokonolin-derivat
SE402106B (sv) Forfarande for framstellning av nya n-(Ÿ-amino)-alkylanilinderivat
SE435715B (sv) Forfarande for framstellning av nya penicilliner
SE7612565L (sv) Forfarande for framstellning av nya rifamycinforeningar
SE388854B (sv) Forfarande for framstellning av fenylpyridylaminderivat
SE7506196L (sv) Forfarande for framstellning av amidin-hydrazon-derivat
SE414029B (sv) Forfarande for framstellning av terapeutiskt aktiva fentiazinderivat
SE405356B (sv) Forfarande att framstella nya farmaceutiskt anvendbara derivat av 2-aminoalkyl-3-fenyl-isoindol
SE7606815L (sv) Forfarande for framstellning av nya naftacenderivat
SE411754B (sv) Forfarande for framstellning av terapeutiskt aktiva nya derivat av n-(2-pyrrolidinylalkyl)-bensamid