SE384856B - Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan - Google Patents

Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan

Info

Publication number
SE384856B
SE384856B SE7214215A SE1421572A SE384856B SE 384856 B SE384856 B SE 384856B SE 7214215 A SE7214215 A SE 7214215A SE 1421572 A SE1421572 A SE 1421572A SE 384856 B SE384856 B SE 384856B
Authority
SE
Sweden
Prior art keywords
analgetic
inflammatory
way
antipyretic effects
preparing content
Prior art date
Application number
SE7214215A
Other languages
English (en)
Swedish (sv)
Inventor
G R Birchall
W Hepworth
S C Smith
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of SE384856B publication Critical patent/SE384856B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE7214215A 1971-11-03 1972-11-02 Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan SE384856B (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1811672A GB1356834A (en) 1971-11-03 1971-11-03 Indole derivatives
GB1811672 1972-04-19
GB3076772 1972-06-30

Publications (1)

Publication Number Publication Date
SE384856B true SE384856B (sv) 1976-05-24

Family

ID=27257588

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7214215A SE384856B (sv) 1971-11-03 1972-11-02 Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan

Country Status (17)

Country Link
US (1) US3884919A (enExample)
JP (1) JPS4856667A (enExample)
AR (3) AR198064A1 (enExample)
BE (1) BE790679A (enExample)
CA (1) CA983932A (enExample)
CH (1) CH577499A5 (enExample)
DD (1) DD105611A5 (enExample)
DE (1) DE2253927A1 (enExample)
EG (1) EG11358A (enExample)
ES (2) ES408226A1 (enExample)
FR (1) FR2158464B1 (enExample)
GB (1) GB1356834A (enExample)
HU (1) HU169711B (enExample)
IE (1) IE37998B1 (enExample)
IL (1) IL40521A (enExample)
NL (1) NL7214807A (enExample)
SE (1) SE384856B (enExample)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4022780A (en) * 1973-03-06 1977-05-10 Imperial Chemical Industries Limited Process for the manufacture of indole derivatives
FR2421900A1 (fr) * 1977-03-17 1979-11-02 Sauba Lab Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques
US4316847A (en) * 1979-07-30 1982-02-23 Hoffmann-La Roche Inc. Pyrroles and pyrrolidines
US4459227A (en) * 1981-03-02 1984-07-10 Duke University Para-hydroxyphenylhydrazines as in situ precursors of iminoquinones and quinones
RU2137762C1 (ru) * 1994-02-23 1999-09-20 Пфайзер Инк. 4-гетероциклил-замещенные производные хиназолина, фармацевтическая композиция
US6252084B1 (en) * 1994-03-15 2001-06-26 Eli Lilly And Company 1H-indole-3-acetamide sPLA2 inhibitors
SK12752000A3 (sk) * 1998-02-25 2001-03-12 Genetics Institute, Inc. Inhibítory fosfolipázových enzýmov, farmaceutický prostriedok s ich obsahom a ich použitie
US6500853B1 (en) 1998-02-28 2002-12-31 Genetics Institute, Llc Inhibitors of phospholipase enzymes
SE0200356D0 (sv) * 2002-02-05 2002-02-05 Astrazeneca Ab Novel use
SE0200411D0 (sv) * 2002-02-05 2002-02-05 Astrazeneca Ab Novel use
SE0201635D0 (sv) * 2002-05-30 2002-05-30 Astrazeneca Ab Novel compounds
TW200307542A (en) 2002-05-30 2003-12-16 Astrazeneca Ab Novel compounds
SE0202241D0 (sv) 2002-07-17 2002-07-17 Astrazeneca Ab Novel Compounds
SE0301010D0 (sv) * 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
SE0301009D0 (sv) * 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
PT1471057E (pt) 2003-04-25 2006-05-31 Actimis Pharmaceuticals Inc Derivados de acido pirimidinilacetico uteis para o tratamento de doencas mediadas por crth2
MXPA05011523A (es) * 2003-04-30 2006-01-23 Inst For Pharm Discovery Inc Heteroarilos sustituidos como inhibidores de proteinas de tirosina fosfatasas.
SE0301569D0 (sv) 2003-05-27 2003-05-27 Astrazeneca Ab Novel compounds
SE0302232D0 (sv) * 2003-08-18 2003-08-18 Astrazeneca Ab Novel Compounds
SA04250253B1 (ar) 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
GB0324763D0 (en) 2003-10-23 2003-11-26 Oxagen Ltd Use of compounds in therapy
SE0303180D0 (sv) 2003-11-26 2003-11-26 Astrazeneca Ab Novel compounds
CN100584844C (zh) 2004-01-31 2010-01-27 艾克提麦斯医药品有限公司 咪唑[1,2-c]嘧啶基乙酸衍生物
GB0415320D0 (en) 2004-07-08 2004-08-11 Astrazeneca Ab Novel compounds
GB0418830D0 (en) 2004-08-24 2004-09-22 Astrazeneca Ab Novel compounds
UY29223A1 (es) 2004-11-23 2006-06-30 Astrazeneca Ab Ácidos fenoxiacéticos sustituidos, composiciones farmacéuticas que los contienen y procesos para su preparación
GB0500604D0 (en) 2005-01-13 2005-02-16 Astrazeneca Ab Novel process
TW200745003A (en) 2005-10-06 2007-12-16 Astrazeneca Ab Novel compounds
EP1937632A1 (en) 2005-10-06 2008-07-02 Astra Zeneca AB Novel compounds
JP2009538289A (ja) 2006-05-26 2009-11-05 アストラゼネカ・アクチエボラーグ ビアリールまたはヘテロアリール置換インドール
CA2658496A1 (en) 2006-07-22 2008-01-31 Oxagen Limited 2-{5-fluoro-2-methyl-3-[2-(phenylsulfonyl)benzyl]-1h-indol-yl} acetic acid derivatives and esters thereof having crth2 antagonist activity
UA100983C2 (ru) 2007-07-05 2013-02-25 Астразенека Аб Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
JP5524847B2 (ja) 2007-09-25 2014-06-18 アクチミス ファーマシューティカルズ インコーポレーテッド Ｃｒｔｈ２アンタゴニストとしてのアルキルチオピリミジン
BRPI0817318A2 (pt) 2007-09-25 2015-03-17 Actimis Pharmaceuticals Inc Composto, composição farmacêutica, e, método para tratar uma doença, ou uma condição, ou sintoma da mesma.
CA2712017C (en) 2008-01-18 2016-08-09 Oxagen Limited Compounds having crth2 antagonist activity
US7750027B2 (en) 2008-01-18 2010-07-06 Oxagen Limited Compounds having CRTH2 antagonist activity
EP2265581A1 (en) 2008-01-22 2010-12-29 Oxagen Limited Compounds having crth2 antagonist activity
JP2011509991A (ja) 2008-01-22 2011-03-31 オキサジェン リミテッド Ｃｒｔｈ２アンタゴニスト活性を有する化合物
GB201322273D0 (en) 2013-12-17 2014-01-29 Atopix Therapeutics Ltd Process
GB201407820D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
GB201407807D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
CA3114672A1 (en) * 2018-10-05 2020-04-23 Vertex Pharmaceuticals Incorporated Modulators of alpha-1 antitrypsin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL125443C (enExample) * 1963-06-06
US3679692A (en) * 1969-10-01 1972-07-25 Mead Johnson & Co Iminomethylindolines

Also Published As

Publication number Publication date
ES437311A1 (es) 1977-04-01
AR203626A1 (es) 1975-09-30
NL7214807A (enExample) 1973-05-07
IE37998B1 (en) 1977-12-07
IE37998L (en) 1973-05-03
FR2158464B1 (enExample) 1976-07-02
HU169711B (enExample) 1977-02-28
AR203627A1 (es) 1975-09-30
JPS4856667A (enExample) 1973-08-09
CH577499A5 (enExample) 1976-07-15
DD105611A5 (enExample) 1974-05-05
GB1356834A (en) 1974-06-19
EG11358A (en) 1977-02-28
FR2158464A1 (enExample) 1973-06-15
AR198064A1 (es) 1974-05-31
IL40521A0 (en) 1972-12-29
BE790679A (fr) 1973-04-27
CA983932A (en) 1976-02-17
ES408226A1 (es) 1976-02-01
IL40521A (en) 1975-06-25
DE2253927A1 (de) 1973-05-10
US3884919A (en) 1975-05-20

Similar Documents

Publication Publication Date Title
SE384856B (sv) Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan
FI55379C (fi) Polyolefinmassa med baettre vattenavledningsegenskaper foer framstaellning av papper och massans framstaellningsfoerfarande
SE7602339L (sv) Kinolonderivat och sett att framstella desamma
SE398877B (sv) Forfarande for framstellning av 14-hydroxi-morfinanderivat
SE402283B (sv) Karbazoler med antiinflammatorisk, analgetisk och antireumatisk verkan
SE7605925L (sv) Nya prostanderivat och sett att framstella desamma
SE405599B (sv) Forfarande for framstellning av pyridazinoner med terapeutisk verkan
SE406197B (sv) Analogiforfarande for framstellning av 4-aminokinazolinderivat
SE7508544L (sv) Bensimidazol-derivat och sett att framstella desamma.
BE786155A (fr) Derives heterocycliques n-substitues ainsi que leur preparation
SE397523B (sv) Forfarande att framstella n-fenylpyrrolderivat med antiinflammatorisk och analgetisk verkan
FI54592C (fi) Foerpackning av straengar av med adhesionsmedel belagda glasfibrer och foerfarande foer framstaellning av foerpackningen
FI56100B (fi) Loesningskoncentrat med fungicid och acaricid verkan
SE395892B (sv) Forfarande for framstellning av piperidyl-bensimidazoliner med terapeutisk verkan
SE392615B (sv) Forfarande for framstellning av 2-nitro-5-imidazolaldehydderivat
SE384686B (sv) Forfarande for framstellning av linkomycinderivat
SE399069B (sv) Analogiforfarande for framstellning av triazolo-pyridino-isokinolin-derivat
SE385896B (sv) Forfarande for framstellning av 2,3-dihydro-4h-tieno-(3,2-c)(1)bensopyran-4-oner med analgetisk och antipyretisk verkan
FI53790C (fi) Foerfarande och anordning foer styrd gjutning av en form med smaelt metall
SE401829B (sv) Forfarande for framstellning av 5-fenyl-6,7-bensomorfanderivat och salter derav
SE409866B (sv) Forfarande for framstellning av adenosinderivat
IT956656B (it) Composti disazoici loro preparazio ne e loro impiego
SE390509B (sv) Forfarande for framstellning av skivor av trematerial
SE408930B (sv) Stativ for borrplattform och sett att bygga detsamma
SE385897B (sv) Forfarande for framstellning av bensoditianpyronderivat med terapeutisk verkan