IL40521A - 1-heterocyclyl-3-indolealkanoic acid derivatives - Google Patents
1-heterocyclyl-3-indolealkanoic acid derivativesInfo
- Publication number
- IL40521A IL40521A IL40521A IL4052172A IL40521A IL 40521 A IL40521 A IL 40521A IL 40521 A IL40521 A IL 40521A IL 4052172 A IL4052172 A IL 4052172A IL 40521 A IL40521 A IL 40521A
- Authority
- IL
- Israel
- Prior art keywords
- heterocyclyl
- acid derivatives
- indolealkanoic
- indolealkanoic acid
- derivatives
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1811672A GB1356834A (en) | 1971-11-03 | 1971-11-03 | Indole derivatives |
| GB1811672 | 1972-04-19 | ||
| GB3076772 | 1972-06-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL40521A0 IL40521A0 (en) | 1972-12-29 |
| IL40521A true IL40521A (en) | 1975-06-25 |
Family
ID=27257588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL40521A IL40521A (en) | 1971-11-03 | 1972-10-06 | 1-heterocyclyl-3-indolealkanoic acid derivatives |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3884919A (enExample) |
| JP (1) | JPS4856667A (enExample) |
| AR (3) | AR198064A1 (enExample) |
| BE (1) | BE790679A (enExample) |
| CA (1) | CA983932A (enExample) |
| CH (1) | CH577499A5 (enExample) |
| DD (1) | DD105611A5 (enExample) |
| DE (1) | DE2253927A1 (enExample) |
| EG (1) | EG11358A (enExample) |
| ES (2) | ES408226A1 (enExample) |
| FR (1) | FR2158464B1 (enExample) |
| GB (1) | GB1356834A (enExample) |
| HU (1) | HU169711B (enExample) |
| IE (1) | IE37998B1 (enExample) |
| IL (1) | IL40521A (enExample) |
| NL (1) | NL7214807A (enExample) |
| SE (1) | SE384856B (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4022780A (en) * | 1973-03-06 | 1977-05-10 | Imperial Chemical Industries Limited | Process for the manufacture of indole derivatives |
| FR2421900A1 (fr) * | 1977-03-17 | 1979-11-02 | Sauba Lab | Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques |
| US4316847A (en) * | 1979-07-30 | 1982-02-23 | Hoffmann-La Roche Inc. | Pyrroles and pyrrolidines |
| US4459227A (en) * | 1981-03-02 | 1984-07-10 | Duke University | Para-hydroxyphenylhydrazines as in situ precursors of iminoquinones and quinones |
| RU2137762C1 (ru) * | 1994-02-23 | 1999-09-20 | Пфайзер Инк. | 4-гетероциклил-замещенные производные хиназолина, фармацевтическая композиция |
| US6252084B1 (en) * | 1994-03-15 | 2001-06-26 | Eli Lilly And Company | 1H-indole-3-acetamide sPLA2 inhibitors |
| SK12752000A3 (sk) * | 1998-02-25 | 2001-03-12 | Genetics Institute, Inc. | Inhibítory fosfolipázových enzýmov, farmaceutický prostriedok s ich obsahom a ich použitie |
| US6500853B1 (en) | 1998-02-28 | 2002-12-31 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| SE0200356D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| SE0200411D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| SE0201635D0 (sv) * | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
| TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
| SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
| SE0301010D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SE0301009D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| PT1471057E (pt) | 2003-04-25 | 2006-05-31 | Actimis Pharmaceuticals Inc | Derivados de acido pirimidinilacetico uteis para o tratamento de doencas mediadas por crth2 |
| MXPA05011523A (es) * | 2003-04-30 | 2006-01-23 | Inst For Pharm Discovery Inc | Heteroarilos sustituidos como inhibidores de proteinas de tirosina fosfatasas. |
| SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
| SE0302232D0 (sv) * | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0324763D0 (en) | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
| SE0303180D0 (sv) | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
| CN100584844C (zh) | 2004-01-31 | 2010-01-27 | 艾克提麦斯医药品有限公司 | 咪唑[1,2-c]嘧啶基乙酸衍生物 |
| GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| UY29223A1 (es) | 2004-11-23 | 2006-06-30 | Astrazeneca Ab | Ácidos fenoxiacéticos sustituidos, composiciones farmacéuticas que los contienen y procesos para su preparación |
| GB0500604D0 (en) | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| EP1937632A1 (en) | 2005-10-06 | 2008-07-02 | Astra Zeneca AB | Novel compounds |
| JP2009538289A (ja) | 2006-05-26 | 2009-11-05 | アストラゼネカ・アクチエボラーグ | ビアリールまたはヘテロアリール置換インドール |
| CA2658496A1 (en) | 2006-07-22 | 2008-01-31 | Oxagen Limited | 2-{5-fluoro-2-methyl-3-[2-(phenylsulfonyl)benzyl]-1h-indol-yl} acetic acid derivatives and esters thereof having crth2 antagonist activity |
| UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
| JP5524847B2 (ja) | 2007-09-25 | 2014-06-18 | アクチミス ファーマシューティカルズ インコーポレーテッド | Ｃｒｔｈ２アンタゴニストとしてのアルキルチオピリミジン |
| BRPI0817318A2 (pt) | 2007-09-25 | 2015-03-17 | Actimis Pharmaceuticals Inc | Composto, composição farmacêutica, e, método para tratar uma doença, ou uma condição, ou sintoma da mesma. |
| CA2712017C (en) | 2008-01-18 | 2016-08-09 | Oxagen Limited | Compounds having crth2 antagonist activity |
| US7750027B2 (en) | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
| EP2265581A1 (en) | 2008-01-22 | 2010-12-29 | Oxagen Limited | Compounds having crth2 antagonist activity |
| JP2011509991A (ja) | 2008-01-22 | 2011-03-31 | オキサジェン リミテッド | Ｃｒｔｈ２アンタゴニスト活性を有する化合物 |
| GB201322273D0 (en) | 2013-12-17 | 2014-01-29 | Atopix Therapeutics Ltd | Process |
| GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| CA3114672A1 (en) * | 2018-10-05 | 2020-04-23 | Vertex Pharmaceuticals Incorporated | Modulators of alpha-1 antitrypsin |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL125443C (enExample) * | 1963-06-06 | |||
| US3679692A (en) * | 1969-10-01 | 1972-07-25 | Mead Johnson & Co | Iminomethylindolines |
-
0
- BE BE790679D patent/BE790679A/xx unknown
-
1971
- 1971-11-03 GB GB1811672A patent/GB1356834A/en not_active Expired
-
1972
- 1972-09-28 IE IE1320/72A patent/IE37998B1/xx unknown
- 1972-09-29 CA CA152,944A patent/CA983932A/en not_active Expired
- 1972-10-06 IL IL40521A patent/IL40521A/xx unknown
- 1972-10-10 US US296202A patent/US3884919A/en not_active Expired - Lifetime
- 1972-10-27 AR AR244863A patent/AR198064A1/es active
- 1972-10-29 EG EG446/72A patent/EG11358A/xx active
- 1972-11-02 FR FR7238836A patent/FR2158464B1/fr not_active Expired
- 1972-11-02 JP JP47110172A patent/JPS4856667A/ja active Pending
- 1972-11-02 NL NL7214807A patent/NL7214807A/xx unknown
- 1972-11-02 SE SE7214215A patent/SE384856B/xx unknown
- 1972-11-02 CH CH1597672A patent/CH577499A5/xx not_active IP Right Cessation
- 1972-11-02 DD DD166646A patent/DD105611A5/xx unknown
- 1972-11-03 DE DE2253927A patent/DE2253927A1/de active Pending
- 1972-11-03 ES ES408226A patent/ES408226A1/es not_active Expired
- 1972-11-03 HU HUIE540A patent/HU169711B/hu unknown
-
1973
- 1973-07-31 AR AR249382A patent/AR203627A1/es active
- 1973-07-31 AR AR249381A patent/AR203626A1/es active
-
1975
- 1975-04-30 ES ES437331A patent/ES437311A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES437311A1 (es) | 1977-04-01 |
| AR203626A1 (es) | 1975-09-30 |
| NL7214807A (enExample) | 1973-05-07 |
| IE37998B1 (en) | 1977-12-07 |
| IE37998L (en) | 1973-05-03 |
| FR2158464B1 (enExample) | 1976-07-02 |
| HU169711B (enExample) | 1977-02-28 |
| AR203627A1 (es) | 1975-09-30 |
| JPS4856667A (enExample) | 1973-08-09 |
| CH577499A5 (enExample) | 1976-07-15 |
| DD105611A5 (enExample) | 1974-05-05 |
| GB1356834A (en) | 1974-06-19 |
| EG11358A (en) | 1977-02-28 |
| FR2158464A1 (enExample) | 1973-06-15 |
| AR198064A1 (es) | 1974-05-31 |
| IL40521A0 (en) | 1972-12-29 |
| BE790679A (fr) | 1973-04-27 |
| CA983932A (en) | 1976-02-17 |
| ES408226A1 (es) | 1976-02-01 |
| SE384856B (sv) | 1976-05-24 |
| DE2253927A1 (de) | 1973-05-10 |
| US3884919A (en) | 1975-05-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL40521A (en) | 1-heterocyclyl-3-indolealkanoic acid derivatives | |
| IL38605A0 (en) | P-methane-carboxamide derivatives | |
| IE36079L (en) | Benzazine derivatives | |
| MY7900027A (en) | 3-substituted-morphinan derivatives | |
| IL39376A0 (en) | Prostanoic acid derivatives | |
| HK22577A (en) | Oxidiazolone derivatives | |
| AU4847172A (en) | Cycloalkylaminoarylcarboxylic acid derivatives | |
| AU4936072A (en) | Citric acid derivatives | |
| ZA728402B (en) | Citric acid derivatives | |
| CA957371A (en) | Carbamoyl-triiodophenoxy-ethoxy-propionic acid derivatives | |
| IE37237L (en) | Pyrroleacetic acid derivatives | |
| IL39880A0 (en) | 2-nitro-5-imidazolaldehyde derivatives | |
| ZA728403B (en) | Citric acid derivatives | |
| IL38936A0 (en) | Lumilysergol derivatives | |
| ZA723158B (en) | 2-p-nitro-or p-chlorobenzamidoaceto-hydroxamic acid | |
| MY7500276A (en) | 2-chloroethanephosphonic acid derivatives | |
| CA967161A (en) | Piperidine-acetic acid derivatives | |
| PH9500A (en) | 6-amino-penicillanic acid derivatives | |
| GB1408201A (en) | Adenosine-5-carboxylate derivatives | |
| CY908A (en) | Triazolyl-ethenyl-phenylene derivatives | |
| GB1405794A (en) | Alpha-thioacetic acid derivatives | |
| GB1402325A (en) | Dibenzoxirenoazepine derivatives | |
| IL39834A0 (en) | Beta-phenyl-beta-fluorethane derivatives | |
| IE37196L (en) | Diphenylpyrazolium derivatives | |
| ZA721364B (en) | Penicilloic acid derivatives |