SE379765B - - Google Patents
Info
- Publication number
- SE379765B SE379765B SE6912617*3A SE1261769A SE379765B SE 379765 B SE379765 B SE 379765B SE 1261769 A SE1261769 A SE 1261769A SE 379765 B SE379765 B SE 379765B
- Authority
- SE
- Sweden
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Glass Melting And Manufacturing (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27523763A | 1963-04-24 | 1963-04-24 | |
US330244A US3366635A (en) | 1963-04-24 | 1963-12-13 | Aza-5h-dibenzo-[a,d]-(cycloheptenes and cycloheptene-5-ones) and the corresponding 10, 11-dihydro derivatives thereof |
US330263A US3326924A (en) | 1963-04-24 | 1963-12-13 | Novel aza-dibenzo[a, d]-cycloheptene derivatives |
US42010164A | 1964-12-21 | 1964-12-21 | |
US580169A US3357986A (en) | 1963-04-24 | 1966-09-19 | 1, 2, 3 or 4, aza,-[5-piperdyl or hydrocarbyl amino]-10, 11 dihydro-5h-dibenzo-[a, d]-cycloheptene |
Publications (1)
Publication Number | Publication Date |
---|---|
SE379765B true SE379765B (nl) | 1975-10-20 |
Family
ID=27540590
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE6912617*3A SE379765B (nl) | 1963-04-24 | 1964-04-23 | |
SE08607/68A SE347745B (nl) | 1963-04-24 | 1968-06-25 | |
SE08610/68A SE349030B (nl) | 1963-04-24 | 1968-06-25 | |
SE08609/68A SE338317B (nl) | 1963-04-24 | 1968-06-25 |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE08607/68A SE347745B (nl) | 1963-04-24 | 1968-06-25 | |
SE08610/68A SE349030B (nl) | 1963-04-24 | 1968-06-25 | |
SE08609/68A SE338317B (nl) | 1963-04-24 | 1968-06-25 |
Country Status (17)
Country | Link |
---|---|
US (3) | US3326924A (nl) |
JP (3) | JPS4840356B1 (nl) |
BE (1) | BE647043A (nl) |
BR (1) | BR6458580D0 (nl) |
CH (2) | CH544091A (nl) |
CY (1) | CY543A (nl) |
DE (2) | DE1695853B2 (nl) |
DK (2) | DK125421B (nl) |
FI (1) | FI52220C (nl) |
FR (1) | FR4013M (nl) |
GB (1) | GB1065191A (nl) |
IL (1) | IL21208A (nl) |
IT (2) | IT1149233B (nl) |
MY (1) | MY7000130A (nl) |
NL (2) | NL6404490A (nl) |
NO (3) | NO120935B (nl) |
SE (4) | SE379765B (nl) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3378567A (en) * | 1965-12-20 | 1968-04-16 | Schering Corp | 5-diloweralkylaminoalkoxy ethers of 4-aza-10, 11-dihydro-5h-dibenzo[a, d]-cycloheptene derivatives |
US3409621A (en) * | 1966-04-01 | 1968-11-05 | Schering Corp | Piperazino-aza-dibenzo-[a, d]-cycloheptenes |
US3458522A (en) * | 1967-05-17 | 1969-07-29 | Sandoz Ag | 4-piperidine substituted benzocycloheptaoxazoles and benzocycloheptathiazoles |
US3458524A (en) * | 1968-03-27 | 1969-07-29 | Schering Corp | Novel 5-alkylaminoalkoximino-aza-dibenzo-(a,d)-cycloheptenes |
FI762546A (nl) * | 1975-09-15 | 1977-03-16 | Sandoz Ag | |
US4092322A (en) * | 1977-02-14 | 1978-05-30 | Warner-Lambert Company | 1-Benzoxepino[4,3-c]pyridines |
US4355036A (en) * | 1980-06-19 | 1982-10-19 | Schering Corporation | Tricyclic-substituted piperidine antihistamines |
US4282233B1 (en) * | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
US4454143A (en) * | 1981-03-16 | 1984-06-12 | Schering Corporation | Tricyclic antihistamines |
JPS61501205A (ja) * | 1984-02-15 | 1986-06-19 | シェリング・コ−ポレ−ション | 8↓−クロル↓−6,11↓−ジヒドロ↓−11↓−(4↓−ピペリジリデン)↓−5H↓−ベンゾ〔5,6〕シクロヘプタ〔1,2−b〕ピリジンおよびその塩、これらの化合物の製造方法、ならびにこれらの化合物を含有する医薬組成物 |
US4834980A (en) * | 1984-07-23 | 1989-05-30 | Schering Corporation | Transdermal delivery of azatidine |
DE3677842D1 (de) * | 1985-05-13 | 1991-04-11 | Schering Corp | Verfahren zur herstellung von piperidyliden-dihydrodibenzo(a,d)zykloheptenen und deren azoderivate, so hergestellte verbindungen und ihre anwendung zur vorbereitung von heilmitteln. |
US4731447A (en) * | 1985-05-13 | 1988-03-15 | Schering Corporation | Process for preparing piperidylidene dihydro-dibenzo(a,d)-cycloheptenes or aza-derivatives thereof |
US4804666A (en) * | 1985-08-14 | 1989-02-14 | Schering Corporation | Antiallergic 6,11-dihydro-11-(4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines |
US4639457A (en) * | 1985-08-19 | 1987-01-27 | Merck & Co., Inc. | Benzocycloheptapyridone compounds for treating congestive heart failure |
US4873335A (en) * | 1986-03-12 | 1989-10-10 | Schering Corporation | 3-phenethyl-2-benzene-amides or aza-derivatives thereof |
US5011860A (en) * | 1986-04-11 | 1991-04-30 | Schering Corporation | Aryl-substituted naphthyridine and pyridopyrazine derivatives and their use in treating hyperproliferative skin diseases |
US5438062A (en) * | 1986-10-31 | 1995-08-01 | Schering Corporation | Benzo(5,6)cycloheptapyridines, compositions and methods of use |
US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
US5665726A (en) * | 1986-10-31 | 1997-09-09 | Schering Corporation | Benzo[5,6]cycloheptapyridines, compositions and methods of use |
US4843163A (en) * | 1987-12-02 | 1989-06-27 | Smithkline Beckman Corporation | Certain 3-(2-phenethyl)-1-carbamoyloxypyridinium halide intermediates |
JP2766266B2 (ja) * | 1988-06-20 | 1998-06-18 | 協和醗酵工業株式会社 | ピリジン誘導体およびその中間体 |
US4863931A (en) * | 1988-09-15 | 1989-09-05 | Schering Corporation | Antihistaminic fluoro substituted benzocycloheptapyridines |
US4996321A (en) * | 1990-02-26 | 1991-02-26 | Merck & Co., Inc. | Dibenzo[a,d]cycloheptenylidene compounds |
IL98572A (en) * | 1990-06-22 | 1995-07-31 | Schering Corp | Bite-benzo or benzopyrido compounds Cyclohepta piperidine, piperidylidene and piperazine, preparations and methods of use. |
EP0552245A1 (en) * | 1990-10-10 | 1993-07-28 | Schering Corporation | Bis-benzo cyclohepta piperidylidene, piperidine and piperazine compounds, compositions and methods of use |
CA2109702A1 (en) * | 1991-05-23 | 1992-11-26 | Jesse K. Wong | Novel benzopyrido piperidylidene compounds, compositions, methods of manufacture and methods of use |
JPH06509341A (ja) * | 1991-07-23 | 1994-10-20 | シェリング・コーポレーション | 新規ベンゾピリドピペリジリデン化合物、組成物、製造方法および使用方法 |
ES2040177B1 (es) * | 1992-03-06 | 1994-05-16 | S A Tamarang | Procedimiento para la sintesis de la 8-cloro-6, 11-dihidro-11, (1-etoxicarbonil-4-piperidiliden) -5h-benzo (5,6) ciclohepta-(1,2-b) piridina. |
NZ251540A (en) * | 1992-03-27 | 1996-09-25 | Schering Corp | Bridged bis-aryl carbinol derivatives, preparation and medicaments |
DK0635012T3 (da) * | 1992-03-27 | 1996-08-19 | Schering Corp | Bis-aryl-carbinolderivater uden broer, præparater indeholdende disse og fremgangsmåder til anvendelse af disse |
AU4244593A (en) * | 1992-05-19 | 1993-12-13 | Schering Corporation | Pentacyclic antihistamines |
US5464840A (en) * | 1993-12-06 | 1995-11-07 | Schering Corporation | Tricyclic derivatives, compositions and methods of use |
US7211582B1 (en) * | 1994-12-30 | 2007-05-01 | Sepracor Inc. | Methods for treating urticaria using descarboethoxyloratadine |
US5801175A (en) | 1995-04-07 | 1998-09-01 | Schering Corporation | Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
EP0913392B1 (en) * | 1996-04-25 | 2003-07-02 | Nissan Chemical Industries, Limited | Ethylene derivatives and pest controlling agents |
US6509346B2 (en) * | 1998-01-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
WO2000005215A1 (en) * | 1998-07-24 | 2000-02-03 | Russinsky Limited | A process for preparing benzocycloheptapyridin-11-ones |
US6267986B1 (en) | 1999-09-24 | 2001-07-31 | Ranbaxy Laboratories Limited | Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine |
US7541365B2 (en) * | 2001-11-21 | 2009-06-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
WO2003084931A1 (en) * | 2002-04-02 | 2003-10-16 | Merck & Co., Inc. | 5h-benzo[4,5]cyclohepta[1,2-b]pyridine nmda/nr2b antagonists |
KR101067795B1 (ko) * | 2002-08-30 | 2011-09-27 | 니코메드 게엠베하 | 알레르기성 비염을 치료하기 위한 사이클레소나이드 및 항히스타민제의 조합물의 용도 |
TWI291467B (en) | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
PL1507531T3 (pl) * | 2003-03-12 | 2007-06-29 | Teva Pharma | Trwałe kompozycje farmaceutyczne desloratadyny |
NL1026634C2 (nl) * | 2004-07-12 | 2006-01-16 | Willem Jacob Van Der Burg | Psychofarmaceutisch preparaat en werkzame stof daarin. |
ATE524445T1 (de) | 2005-06-23 | 2011-09-15 | Merck Sharp & Dohme | Benzocycloheptapyridine als inhibitoren der tyrosinkinase met |
US20070036859A1 (en) * | 2005-08-11 | 2007-02-15 | Perry Ronald L | Sustained release antihistamine and decongestant composition |
JP2009513580A (ja) * | 2005-10-21 | 2009-04-02 | メルク エンド カムパニー インコーポレーテッド | チロシンキナーゼ阻害剤 |
NZ573174A (en) | 2006-06-01 | 2012-01-12 | Msd Consumer Care Inc | Sustained release pharmaceutical dosage form containing phenylephrine |
NZ573173A (en) | 2006-06-01 | 2012-03-30 | Msd Consumer Care Inc | Phenylephrine pharmaceutical formulation and compositions for colonic absorption |
TW200813021A (en) * | 2006-07-10 | 2008-03-16 | Merck & Co Inc | Tyrosine kinase inhibitors |
US20090082385A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched desloratidine |
JP2011507895A (ja) * | 2007-12-21 | 2011-03-10 | シェーリング−プラウ ヘルスケア プロダクツ,インコーポレイテッド | オキシメタゾリンの増強された光安定化 |
CN102993172B (zh) * | 2012-12-19 | 2014-04-02 | 天津大学 | 具有抗组胺活性的三环类化合物、制备方法及用途 |
GB202103803D0 (en) | 2021-03-18 | 2021-05-05 | Queens Univ Of Belfast | Anti-viral therapy |
CN112898268A (zh) * | 2021-04-07 | 2021-06-04 | 深圳振强生物技术有限公司 | 一种地氯雷他定杂质的制备方法 |
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Publication number | Priority date | Publication date | Assignee | Title |
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GB858187A (en) * | 1958-04-03 | 1961-01-11 | Hoffmann La Roche | Novel dibenzocycloheptaenes and salts thereof and a process for the manufacture of same |
GB858186A (en) * | 1958-04-03 | 1961-01-11 | Hoffmann La Roche | Novel dibenzoheptaenes and salts thereof and a process for the manufacture of same |
US3014911A (en) * | 1958-09-29 | 1961-12-26 | Merck & Co Inc | Derivatives of dibenzo[a, e]cycloheptatriene |
US3073847A (en) * | 1959-02-12 | 1963-01-15 | Hoffmann La Roche | 9-(3-amino-1-propynyl) derivatives of 9-xanthenols and 9-thioxanthenols and a process for their preparation |
DE1160442B (de) * | 1959-03-18 | 1964-01-02 | Degussa | Verfahren zur Herstellung von 3-Trifluormethylphenthiazinen |
US3086972A (en) * | 1960-03-24 | 1963-04-23 | Sandoz Ag | Aza-thiaxanthene derivatives |
US3127409A (en) * | 1962-08-08 | 1964-03-31 | Olin Mathieson | Novel dihydropyridobenzoxazepines and dihydropyridobenzthiazepines |
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0
- NL NL132137D patent/NL132137C/xx active
-
1963
- 1963-12-13 US US330263A patent/US3326924A/en not_active Expired - Lifetime
- 1963-12-13 US US330244A patent/US3366635A/en not_active Expired - Lifetime
-
1964
- 1964-04-20 CH CH584573A patent/CH544091A/de not_active IP Right Cessation
- 1964-04-20 CH CH509564A patent/CH535769A/de not_active IP Right Cessation
- 1964-04-20 IL IL21208A patent/IL21208A/xx unknown
- 1964-04-21 GB GB16484/64A patent/GB1065191A/en not_active Expired
- 1964-04-22 BR BR158580/64A patent/BR6458580D0/pt unknown
- 1964-04-23 FR FR972072A patent/FR4013M/fr not_active Expired
- 1964-04-23 NL NL6404490A patent/NL6404490A/xx unknown
- 1964-04-23 DE DE1964SC041153 patent/DE1695853B2/de active Granted
- 1964-04-23 DE DE19641795744 patent/DE1795744A1/de active Pending
- 1964-04-23 DK DK205164AA patent/DK125421B/da unknown
- 1964-04-23 FI FI640863A patent/FI52220C/fi active
- 1964-04-23 NO NO152953A patent/NO120935B/no unknown
- 1964-04-23 IT IT08873/64A patent/IT1149233B/it active
- 1964-04-23 SE SE6912617*3A patent/SE379765B/xx unknown
- 1964-04-24 JP JP39022868A patent/JPS4840356B1/ja active Pending
- 1964-04-24 BE BE647043D patent/BE647043A/xx unknown
-
1966
- 1966-08-17 NO NO66164332A patent/NO121949B/no unknown
- 1966-08-17 NO NO66164333A patent/NO120938B/no unknown
- 1966-09-19 US US580169A patent/US3357986A/en not_active Expired - Lifetime
-
1968
- 1968-06-25 SE SE08607/68A patent/SE347745B/xx unknown
- 1968-06-25 SE SE08610/68A patent/SE349030B/xx unknown
- 1968-06-25 SE SE08609/68A patent/SE338317B/xx unknown
-
1969
- 1969-09-09 DK DK482469AA patent/DK125133B/da unknown
-
1970
- 1970-06-26 CY CY54370A patent/CY543A/xx unknown
- 1970-12-31 MY MY1970130A patent/MY7000130A/xx unknown
-
1972
- 1972-02-28 IT IT21129/72A patent/IT1123902B/it active
-
1973
- 1973-05-25 JP JP7358499A patent/JPS5030077B1/ja active Pending
- 1973-05-25 JP JP48058500A patent/JPS5030078B1/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL21208A (en) | 1968-10-24 |
NO120938B (nl) | 1970-12-28 |
IT1123902B (it) | 1986-04-30 |
DE1795744A1 (de) | 1974-11-21 |
US3366635A (en) | 1968-01-30 |
BE647043A (nl) | 1964-10-26 |
US3357986A (en) | 1967-12-12 |
FI52220C (fi) | 1977-07-11 |
DE1795745A1 (de) | 1974-08-29 |
SE347745B (nl) | 1972-08-14 |
CY543A (en) | 1970-06-26 |
NO121949B (nl) | 1971-05-03 |
DK125421B (da) | 1973-02-19 |
NO120935B (nl) | 1970-12-28 |
SE338317B (nl) | 1971-09-06 |
JPS5030077B1 (nl) | 1975-09-29 |
DK125133B (da) | 1973-01-02 |
JPS4840356B1 (nl) | 1973-11-30 |
NL6404490A (nl) | 1964-10-26 |
FR4013M (nl) | 1966-03-21 |
GB1065191A (en) | 1967-04-12 |
NL132137C (nl) | |
JPS5030078B1 (nl) | 1975-09-29 |
BR6458580D0 (pt) | 1973-09-11 |
CH544091A (de) | 1973-12-28 |
IT1149233B (it) | 1986-12-03 |
SE349030B (nl) | 1972-09-18 |
DE1695853A1 (de) | 1972-03-02 |
MY7000130A (en) | 1970-12-31 |
DE1795745B2 (de) | 1976-04-08 |
DE1695853B2 (de) | 1976-06-16 |
US3326924A (en) | 1967-06-20 |
FI52220B (nl) | 1977-03-31 |
CH535769A (de) | 1973-04-15 |