SE0301119D0 - New non-ionic surfactants for solubilizing poorly soluble molecules - Google Patents

New non-ionic surfactants for solubilizing poorly soluble molecules

Info

Publication number
SE0301119D0
SE0301119D0 SE0301119A SE0301119A SE0301119D0 SE 0301119 D0 SE0301119 D0 SE 0301119D0 SE 0301119 A SE0301119 A SE 0301119A SE 0301119 A SE0301119 A SE 0301119A SE 0301119 D0 SE0301119 D0 SE 0301119D0
Authority
SE
Sweden
Prior art keywords
ionic surfactants
new non
fatty acid
polyoxyalkylene
poorly soluble
Prior art date
Application number
SE0301119A
Other languages
English (en)
Swedish (sv)
Inventor
Christian Von Corswant
Karl Hult
Erik Soederlind
Fredrik Viklund
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0301119A priority Critical patent/SE0301119D0/xx
Publication of SE0301119D0 publication Critical patent/SE0301119D0/xx
Priority to PCT/SE2004/000572 priority patent/WO2004089869A1/en
Priority to JP2006508018A priority patent/JP4589917B2/ja
Priority to MXPA05010893A priority patent/MXPA05010893A/es
Priority to CN2004800098771A priority patent/CN1774414B/zh
Priority to KR1020057019461A priority patent/KR101091324B1/ko
Priority to CA2521612A priority patent/CA2521612C/en
Priority to US10/553,275 priority patent/US7491836B2/en
Priority to BRPI0408972-3A priority patent/BRPI0408972A/pt
Priority to EP04727166.3A priority patent/EP1615874B1/en
Priority to AU2004228602A priority patent/AU2004228602B2/en
Priority to NZ542752A priority patent/NZ542752A/en
Priority to ES04727166.3T priority patent/ES2445821T3/es
Priority to IL171058A priority patent/IL171058A/en
Priority to ZA200508247A priority patent/ZA200508247B/en
Priority to NO20055331A priority patent/NO20055331L/no
Priority to HK06110149.3A priority patent/HK1089747A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polyethers (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
SE0301119A 2003-04-14 2003-04-14 New non-ionic surfactants for solubilizing poorly soluble molecules SE0301119D0 (sv)

Priority Applications (17)

Application Number Priority Date Filing Date Title
SE0301119A SE0301119D0 (sv) 2003-04-14 2003-04-14 New non-ionic surfactants for solubilizing poorly soluble molecules
ES04727166.3T ES2445821T3 (es) 2003-04-14 2004-04-13 Nuevos tensoactivos no iónicos para solubilizar moléculas pobremente solubles
CA2521612A CA2521612C (en) 2003-04-14 2004-04-13 Non-ionic surfactant comprising polyoxyalkylene glycol hydroxy fatty acid derivatives for solubilizing poorly soluble molecules
BRPI0408972-3A BRPI0408972A (pt) 2003-04-14 2004-04-13 composto, formulação, uso de um composto, e, processo para a preparação de um éster de polioxialquileno glicol
MXPA05010893A MXPA05010893A (es) 2003-04-14 2004-04-13 Nuevos agentes tensioactivos no ionicos para solubilizar moleculas pobremente solubles.
CN2004800098771A CN1774414B (zh) 2003-04-14 2004-04-13 用于溶解可溶性差的分子的新型非离子表面活性剂
KR1020057019461A KR101091324B1 (ko) 2003-04-14 2004-04-13 용해성이 불량한 분자를 가용화하기 위한 신규 비이온계계면활성제
PCT/SE2004/000572 WO2004089869A1 (en) 2003-04-14 2004-04-13 New non-ionic surfactants for solubilizing poorly soluble molecules
US10/553,275 US7491836B2 (en) 2003-04-14 2004-04-13 Non-ionic surfactants for poorly soluble molecules
JP2006508018A JP4589917B2 (ja) 2003-04-14 2004-04-13 低可溶性分子を可溶化するための新しい非イオン性界面活性剤
EP04727166.3A EP1615874B1 (en) 2003-04-14 2004-04-13 New non-ionic surfactants for solubilizing poorly soluble molecules
AU2004228602A AU2004228602B2 (en) 2003-04-14 2004-04-13 New non-ionic surfactants for solubilizing poorly soluble molecules
NZ542752A NZ542752A (en) 2003-04-14 2004-04-13 New non-ionic surfactants for solubilizing poorly soluble molecules
IL171058A IL171058A (en) 2003-04-14 2005-09-22 Polyoxyalkylene glycols or esterified monoalkylated polyoxyalkylene glycols, formulations comprising them and use thereof as surfactants and in the preparation of formulations including pharmaceutical formulations
ZA200508247A ZA200508247B (en) 2003-04-14 2005-10-12 New non-ionic surfactants for solubilizing poorly soluble molecules
NO20055331A NO20055331L (no) 2003-04-14 2005-11-11 Nye ikke-ioniske overflateaktive stoffer for a opplose darlig loselige molekyler
HK06110149.3A HK1089747A1 (en) 2003-04-14 2006-09-13 New non-ionic surfactants for solubilizing poorly soluble molecules

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0301119A SE0301119D0 (sv) 2003-04-14 2003-04-14 New non-ionic surfactants for solubilizing poorly soluble molecules

Publications (1)

Publication Number Publication Date
SE0301119D0 true SE0301119D0 (sv) 2003-04-14

Family

ID=20291043

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0301119A SE0301119D0 (sv) 2003-04-14 2003-04-14 New non-ionic surfactants for solubilizing poorly soluble molecules

Country Status (17)

Country Link
US (1) US7491836B2 (zh)
EP (1) EP1615874B1 (zh)
JP (1) JP4589917B2 (zh)
KR (1) KR101091324B1 (zh)
CN (1) CN1774414B (zh)
AU (1) AU2004228602B2 (zh)
BR (1) BRPI0408972A (zh)
CA (1) CA2521612C (zh)
ES (1) ES2445821T3 (zh)
HK (1) HK1089747A1 (zh)
IL (1) IL171058A (zh)
MX (1) MXPA05010893A (zh)
NO (1) NO20055331L (zh)
NZ (1) NZ542752A (zh)
SE (1) SE0301119D0 (zh)
WO (1) WO2004089869A1 (zh)
ZA (1) ZA200508247B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090280429A1 (en) * 2008-05-08 2009-11-12 Xerox Corporation Polyester synthesis
GB201115634D0 (en) * 2011-09-09 2011-10-26 Univ Liverpool Compositions of lopinavir
EP2844303B1 (en) * 2012-05-03 2021-09-15 Beth Israel Deaconess Medical Center, Inc. Lipids that increase insulin sensitivity and methods of using the same
WO2014144777A2 (en) 2013-03-15 2014-09-18 Beth Israel Deaconess Medical Center, Inc. Lipids that increase insulin sensitivity and methods of using the same
US9284583B2 (en) * 2014-07-16 2016-03-15 Eastman Chemical Company Enzyme-catalyzed polyoxyalkylene esters
WO2017214527A1 (en) 2016-06-10 2017-12-14 Beth Israel Deaconess Medical Center, Inc. Fatty acid esters of hydroxy fatty acids (fahfas) for use in the treatment of type 1 diabetes
CN107664676A (zh) * 2016-07-29 2018-02-06 中国石油化工股份有限公司 基于增粘型乳液增溶水速率分析方法
KR20210054523A (ko) * 2018-09-05 2021-05-13 론자 광저우 난샤 리미티드 폴리옥시에틸렌 1,4-소르비탄 지방산 에스테르의 제조 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2911241A1 (de) * 1979-03-22 1980-10-02 Basf Ag Alkoxylierte fettsaeuren, verfahren zu deren herstellung und ihre anwendung als loesungsvermittler
JPS5969135A (ja) 1982-10-12 1984-04-19 Nippon Oil & Fats Co Ltd 可溶化または乳化剤
JPS61187795A (ja) * 1985-02-15 1986-08-21 Dai Ichi Kogyo Seiyaku Co Ltd ポリグリセリン脂肪酸エステルの製造法
RU2158601C2 (ru) * 1994-11-03 2000-11-10 Новартис Аг Новые лекарственные формы циклоспорина для орального применения с простым составом и высокой биодоступностью и способ их получения
JP3533043B2 (ja) * 1995-06-19 2004-05-31 三菱化学株式会社 ポリグリセリン脂肪酸エステルの曇点測定方法、該方法を用いる物性評価及び製造方法。
FR2746106B1 (fr) * 1996-03-15 1998-08-28 Combustible emulsionne et l'un de ses procedes d'obtention
JP3610509B2 (ja) * 1996-03-26 2005-01-12 サンノプコ株式会社 消泡剤
DE19622214C2 (de) * 1996-06-03 2000-09-28 Cognis Deutschland Gmbh Verwendung von Hydroxycarbonsäureestern
DE19851777A1 (de) * 1998-11-10 2000-05-11 Basf Ag Verwendung von Estern oder Amiden hydroxylierter Carbonsäuren als Solubilisatoren

Also Published As

Publication number Publication date
CN1774414A (zh) 2006-05-17
CA2521612A1 (en) 2004-10-21
KR101091324B1 (ko) 2011-12-07
MXPA05010893A (es) 2005-11-25
ZA200508247B (en) 2007-03-28
JP2006526048A (ja) 2006-11-16
HK1089747A1 (en) 2006-12-08
AU2004228602B2 (en) 2007-06-14
NZ542752A (en) 2007-05-31
US7491836B2 (en) 2009-02-17
US20060287542A1 (en) 2006-12-21
NO20055331L (no) 2006-01-16
JP4589917B2 (ja) 2010-12-01
IL171058A (en) 2011-04-28
ES2445821T3 (es) 2014-03-05
AU2004228602A1 (en) 2004-10-21
CA2521612C (en) 2012-02-07
BRPI0408972A (pt) 2006-04-04
KR20060004937A (ko) 2006-01-16
CN1774414B (zh) 2010-12-08
NO20055331D0 (no) 2005-11-11
EP1615874A1 (en) 2006-01-18
WO2004089869A1 (en) 2004-10-21
EP1615874B1 (en) 2013-12-25

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