SE0003615L - Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav - Google Patents

Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav

Info

Publication number
SE0003615L
SE0003615L SE0003615A SE0003615A SE0003615L SE 0003615 L SE0003615 L SE 0003615L SE 0003615 A SE0003615 A SE 0003615A SE 0003615 A SE0003615 A SE 0003615A SE 0003615 L SE0003615 L SE 0003615L
Authority
SE
Sweden
Prior art keywords
starch
solution
amylopectin
active substance
biologically active
Prior art date
Application number
SE0003615A
Other languages
English (en)
Other versions
SE0003615D0 (sv
SE517421C2 (sv
Inventor
Monica Joensson
Nils Ove Gustafsson
Timo Laakso
Mats Reslow
Original Assignee
Bioglan Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioglan Ab filed Critical Bioglan Ab
Priority to SE0003615A priority Critical patent/SE517421C2/sv
Publication of SE0003615D0 publication Critical patent/SE0003615D0/sv
Priority to JP2002531996A priority patent/JP2004510723A/ja
Priority to PCT/SE2001/002169 priority patent/WO2002028371A1/en
Priority to CNB018168558A priority patent/CN100352427C/zh
Priority to CA002424936A priority patent/CA2424936A1/en
Priority to AU9445801A priority patent/AU9445801A/xx
Priority to PCT/SE2001/002164 priority patent/WO2002028370A1/en
Priority to CA002424892A priority patent/CA2424892A1/en
Priority to HU0302622A priority patent/HUP0302622A3/hu
Priority to AU2001292529A priority patent/AU2001292529A1/en
Priority to JP2002531997A priority patent/JP2004510724A/ja
Priority to EP01975099A priority patent/EP1322291A1/en
Priority to US09/970,793 priority patent/US6706288B2/en
Priority to EP01972895A priority patent/EP1322290A1/en
Priority to AU2001294458A priority patent/AU2001294458B2/en
Priority to KR10-2003-7004508A priority patent/KR20030051687A/ko
Priority to US09/970,794 priority patent/US20020098203A1/en
Publication of SE0003615L publication Critical patent/SE0003615L/sv
Publication of SE517421C2 publication Critical patent/SE517421C2/sv
Priority to US10/461,445 priority patent/US6692770B2/en
Priority to HK04105106A priority patent/HK1061981A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/22—Coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE0003615A 2000-10-06 2000-10-06 Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav SE517421C2 (sv)

Priority Applications (19)

Application Number Priority Date Filing Date Title
SE0003615A SE517421C2 (sv) 2000-10-06 2000-10-06 Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav
KR10-2003-7004508A KR20030051687A (ko) 2000-10-06 2001-10-05 분자량이 감소된 정제 아밀로펙틴-기제 녹말을 갖는서방투여용 생분해성 미세입자
HU0302622A HUP0302622A3 (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
JP2002531997A JP2004510724A (ja) 2000-10-06 2001-10-05 分子量の低下した澱粉からなる微粒子中に埋め込まれた免疫学的活性物質を含むワクチン組成物
CNB018168558A CN100352427C (zh) 2000-10-06 2001-10-05 用于可控释放给药的,含分子量降低的支链淀粉基纯化淀粉的可生物降解微粒
CA002424936A CA2424936A1 (en) 2000-10-06 2001-10-05 Vaccine composition comprising an immunologically active substance embedded in microparticles consisting of starch with reduced molecular weight
AU9445801A AU9445801A (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
PCT/SE2001/002164 WO2002028370A1 (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
CA002424892A CA2424892A1 (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
JP2002531996A JP2004510723A (ja) 2000-10-06 2001-10-05 低下した分子量のアミロペクチンをベースとする精製された澱粉を含む制御放出投与のための生物分解性微粒子
AU2001292529A AU2001292529A1 (en) 2000-10-06 2001-10-05 Vaccine composition comprising an immunologically active substance embedded in microparticles consisting of starch with reduced molecular weight
PCT/SE2001/002169 WO2002028371A1 (en) 2000-10-06 2001-10-05 Vaccine composition comprising an immunologically active substance embedded in microparticles consisting of starch with reduced molecular weight
EP01975099A EP1322291A1 (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
US09/970,793 US6706288B2 (en) 2000-10-06 2001-10-05 Microparticles
EP01972895A EP1322290A1 (en) 2000-10-06 2001-10-05 Vaccine composition comprising an immunologically active substance embedded in microparticles consisting of starch with reduced molecular weight
AU2001294458A AU2001294458B2 (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
US09/970,794 US20020098203A1 (en) 2000-10-06 2002-01-10 Vaccine composition
US10/461,445 US6692770B2 (en) 2000-10-06 2003-06-16 Starch microparticles
HK04105106A HK1061981A1 (en) 2000-10-06 2004-07-13 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0003615A SE517421C2 (sv) 2000-10-06 2000-10-06 Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav

Publications (3)

Publication Number Publication Date
SE0003615D0 SE0003615D0 (sv) 2000-10-06
SE0003615L true SE0003615L (sv) 2002-04-07
SE517421C2 SE517421C2 (sv) 2002-06-04

Family

ID=20281326

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0003615A SE517421C2 (sv) 2000-10-06 2000-10-06 Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav

Country Status (2)

Country Link
US (2) US6706288B2 (sv)
SE (1) SE517421C2 (sv)

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Also Published As

Publication number Publication date
US20020044976A1 (en) 2002-04-18
US6706288B2 (en) 2004-03-16
US6692770B2 (en) 2004-02-17
SE0003615D0 (sv) 2000-10-06
SE517421C2 (sv) 2002-06-04
US20030211167A1 (en) 2003-11-13

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