SE0003615D0 - Mikropartiklar - Google Patents

Mikropartiklar

Info

Publication number
SE0003615D0
SE0003615D0 SE0003615A SE0003615A SE0003615D0 SE 0003615 D0 SE0003615 D0 SE 0003615D0 SE 0003615 A SE0003615 A SE 0003615A SE 0003615 A SE0003615 A SE 0003615A SE 0003615 D0 SE0003615 D0 SE 0003615D0
Authority
SE
Sweden
Prior art keywords
starch
solution
active substance
biologically active
droplets
Prior art date
Application number
SE0003615A
Other languages
English (en)
Other versions
SE0003615L (sv
SE517421C2 (sv
Inventor
Monica Joensson
Nils Ove Gustafsson
Timo Laakso
Mats Reslow
Original Assignee
Bioglan Therapeutics Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioglan Therapeutics Ab filed Critical Bioglan Therapeutics Ab
Priority to SE0003615A priority Critical patent/SE517421C2/sv
Publication of SE0003615D0 publication Critical patent/SE0003615D0/sv
Priority to EP01972895A priority patent/EP1322290A1/en
Priority to JP2002531997A priority patent/JP2004510724A/ja
Priority to PCT/SE2001/002169 priority patent/WO2002028371A1/en
Priority to CA002424936A priority patent/CA2424936A1/en
Priority to PCT/SE2001/002164 priority patent/WO2002028370A1/en
Priority to AU2001292529A priority patent/AU2001292529A1/en
Priority to CNB018168558A priority patent/CN100352427C/zh
Priority to AU9445801A priority patent/AU9445801A/xx
Priority to KR10-2003-7004508A priority patent/KR20030051687A/ko
Priority to EP01975099A priority patent/EP1322291A1/en
Priority to US09/970,793 priority patent/US6706288B2/en
Priority to AU2001294458A priority patent/AU2001294458B2/en
Priority to HU0302622A priority patent/HUP0302622A3/hu
Priority to JP2002531996A priority patent/JP2004510723A/ja
Priority to CA002424892A priority patent/CA2424892A1/en
Priority to US09/970,794 priority patent/US20020098203A1/en
Publication of SE0003615L publication Critical patent/SE0003615L/sv
Publication of SE517421C2 publication Critical patent/SE517421C2/sv
Priority to US10/461,445 priority patent/US6692770B2/en
Priority to HK04105106A priority patent/HK1061981A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/22—Coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE0003615A 2000-10-06 2000-10-06 Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav SE517421C2 (sv)

Priority Applications (19)

Application Number Priority Date Filing Date Title
SE0003615A SE517421C2 (sv) 2000-10-06 2000-10-06 Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav
CA002424892A CA2424892A1 (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
AU9445801A AU9445801A (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
EP01975099A EP1322291A1 (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
PCT/SE2001/002169 WO2002028371A1 (en) 2000-10-06 2001-10-05 Vaccine composition comprising an immunologically active substance embedded in microparticles consisting of starch with reduced molecular weight
CA002424936A CA2424936A1 (en) 2000-10-06 2001-10-05 Vaccine composition comprising an immunologically active substance embedded in microparticles consisting of starch with reduced molecular weight
PCT/SE2001/002164 WO2002028370A1 (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
AU2001292529A AU2001292529A1 (en) 2000-10-06 2001-10-05 Vaccine composition comprising an immunologically active substance embedded in microparticles consisting of starch with reduced molecular weight
CNB018168558A CN100352427C (zh) 2000-10-06 2001-10-05 用于可控释放给药的,含分子量降低的支链淀粉基纯化淀粉的可生物降解微粒
EP01972895A EP1322290A1 (en) 2000-10-06 2001-10-05 Vaccine composition comprising an immunologically active substance embedded in microparticles consisting of starch with reduced molecular weight
KR10-2003-7004508A KR20030051687A (ko) 2000-10-06 2001-10-05 분자량이 감소된 정제 아밀로펙틴-기제 녹말을 갖는서방투여용 생분해성 미세입자
JP2002531997A JP2004510724A (ja) 2000-10-06 2001-10-05 分子量の低下した澱粉からなる微粒子中に埋め込まれた免疫学的活性物質を含むワクチン組成物
US09/970,793 US6706288B2 (en) 2000-10-06 2001-10-05 Microparticles
AU2001294458A AU2001294458B2 (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
HU0302622A HUP0302622A3 (en) 2000-10-06 2001-10-05 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
JP2002531996A JP2004510723A (ja) 2000-10-06 2001-10-05 低下した分子量のアミロペクチンをベースとする精製された澱粉を含む制御放出投与のための生物分解性微粒子
US09/970,794 US20020098203A1 (en) 2000-10-06 2002-01-10 Vaccine composition
US10/461,445 US6692770B2 (en) 2000-10-06 2003-06-16 Starch microparticles
HK04105106A HK1061981A1 (en) 2000-10-06 2004-07-13 Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0003615A SE517421C2 (sv) 2000-10-06 2000-10-06 Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav

Publications (3)

Publication Number Publication Date
SE0003615D0 true SE0003615D0 (sv) 2000-10-06
SE0003615L SE0003615L (sv) 2002-04-07
SE517421C2 SE517421C2 (sv) 2002-06-04

Family

ID=20281326

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0003615A SE517421C2 (sv) 2000-10-06 2000-10-06 Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav

Country Status (2)

Country Link
US (2) US6706288B2 (sv)
SE (1) SE517421C2 (sv)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6362308B1 (en) * 2000-08-10 2002-03-26 Alkermes Controlled Therapeutics Inc. Ii Acid end group poly(d,l-lactide-co-glycolide) copolymers high glycolide content
SE517422C2 (sv) * 2000-10-06 2002-06-04 Bioglan Ab Farmaceutiskt acceptabel stärkelse
DE10055857A1 (de) * 2000-11-10 2002-08-22 Creative Peptides Sweden Ab Dj Neue pharmazeutische Depotformulierung
SE518008C2 (sv) * 2000-11-16 2002-08-13 Bioglan Ab Parenteralt administrerbara mikropartiklar och förfarande för framställning av desamma
US6767637B2 (en) * 2000-12-13 2004-07-27 Purdue Research Foundation Microencapsulation using ultrasonic atomizers
US7105181B2 (en) * 2001-10-05 2006-09-12 Jagotec, Ag Microparticles
JP4072994B2 (ja) * 2001-10-11 2008-04-09 学校法人日本大学 磁性粒子
SE0201599D0 (sv) * 2002-03-21 2002-05-30 Skyepharma Ab Microparticles
WO2004091770A1 (de) * 2003-04-17 2004-10-28 Innogel Ag Verkapselungssystem
US7772182B2 (en) * 2004-08-05 2010-08-10 Alza Corporation Stable suspension formulations of erythropoietin receptor agonists
US8017152B2 (en) * 2005-05-27 2011-09-13 Stratosphere Pharma Ab Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
US9101949B2 (en) * 2005-08-04 2015-08-11 Eilaz Babaev Ultrasonic atomization and/or seperation system
US20070031611A1 (en) * 2005-08-04 2007-02-08 Babaev Eilaz P Ultrasound medical stent coating method and device
US7896539B2 (en) * 2005-08-16 2011-03-01 Bacoustics, Llc Ultrasound apparatus and methods for mixing liquids and coating stents
US8153180B2 (en) * 2005-09-06 2012-04-10 Pepsico, Inc. Method and apparatus for making beverages
US8241656B2 (en) * 2005-09-21 2012-08-14 Surmodics, Inc Articles including natural biodegradable polysaccharides and uses thereof
US20070065484A1 (en) * 2005-09-21 2007-03-22 Chudzik Stephen J In situ occlusion using natural biodegradable polysaccharides
US20080098900A1 (en) * 2006-11-01 2008-05-01 Babatunde Aremu Beverage manufacture using a static mixer
US20080142616A1 (en) * 2006-12-15 2008-06-19 Bacoustics Llc Method of Producing a Directed Spray
US20100040875A1 (en) * 2006-12-29 2010-02-18 Dow Global Technologies Inc. Films, articles prepared therefrom, and methods of making the same
WO2009005718A1 (en) * 2007-06-28 2009-01-08 Surmodics, Inc. Polypeptide microparticles having sustained release characteristics, methods and uses
US7753285B2 (en) 2007-07-13 2010-07-13 Bacoustics, Llc Echoing ultrasound atomization and/or mixing system
US7780095B2 (en) 2007-07-13 2010-08-24 Bacoustics, Llc Ultrasound pumping apparatus
CA2723192A1 (en) 2008-05-07 2009-11-12 Surmodics, Inc. Delivery of nucleic acid complexes from particles
KR20110020804A (ko) * 2008-05-13 2011-03-03 유니버시티 오브 워싱톤 치료제의 세포내 전달을 위한 미셀
JP5755563B2 (ja) 2008-05-13 2015-07-29 ユニヴァーシティ オブ ワシントン ミセル集合体
WO2009140421A2 (en) * 2008-05-13 2009-11-19 University Of Washington Polymeric carrier
US20110129921A1 (en) * 2008-05-13 2011-06-02 University Of Washington Targeted polymer bioconjugates
JP5911723B2 (ja) * 2008-05-13 2016-04-27 ユニヴァーシティ オブ ワシントン 細胞内に送達するためのジブロックコポリマーおよびそのポリヌクレオチド複合体
US9211250B2 (en) 2008-08-22 2015-12-15 University Of Washington Heterogeneous polymeric micelles for intracellular delivery
US8865678B2 (en) * 2008-10-08 2014-10-21 Conopco, Inc. Universal sensory structurant
US8470802B2 (en) * 2008-10-08 2013-06-25 Conopco, Inc. Sensory modifier
ES2540767T3 (es) 2008-11-06 2015-07-13 University Of Washington Copolímeros multibloque
CA2742955A1 (en) 2008-11-06 2010-05-14 University Of Washington Bispecific intracellular delivery vehicles
EP2373715A4 (en) 2008-12-08 2014-12-03 Univ Washington OMEGA FUNCTIONALIZED POLYMERS, TRANSITIONALIZED BLOCK COPOLYMERS, POLYMER BIOKON JUGATES, AND RADICAL CHAIN EXTENSION POLICY RESPONSE
US8822610B2 (en) * 2008-12-22 2014-09-02 ATRP Solutions, Inc. Control over controlled radical polymerization processes
US8815971B2 (en) 2008-12-22 2014-08-26 ATRP Solutions, Inc. Control over controlled radical polymerization processes
US8569421B2 (en) 2009-04-23 2013-10-29 ATRP Solutions, Inc. Star macromolecules for personal and home care
US8173750B2 (en) 2009-04-23 2012-05-08 ATRP Solutions, Inc. Star macromolecules for personal and home care
WO2014036498A2 (en) 2012-08-30 2014-03-06 ATRP Solutions, Inc. Dual mechanism thickening agents for hydraulic fracturing fluids
US9783628B2 (en) 2009-04-23 2017-10-10 ATRP Solutions, Inc. Dual-mechanism thickening agents for hydraulic fracturing fluids
WO2011062965A2 (en) 2009-11-18 2011-05-26 University Of Washington Through Its Center For Commercialization Targeting monomers and polymers having targeting blocks
US9587064B2 (en) 2010-12-08 2017-03-07 ATRP Solutions, Inc. Salt-tolerant star macromolecules
US8901092B2 (en) 2010-12-29 2014-12-02 Surmodics, Inc. Functionalized polysaccharides for active agent delivery
CN105263978B (zh) 2013-02-04 2018-04-17 Atrp解决方案公司 耐盐星形大分子
CA3160394C (en) 2013-07-30 2023-11-07 Genevant Sciences Gmbh Block copolymers and their conjugates or complexes with oligonucleotides
EP2898894A1 (en) 2014-01-27 2015-07-29 LTS LOHMANN Therapie-Systeme AG Nano-in-micro particles for intradermal delivery
MX2017000076A (es) 2014-07-03 2017-05-01 Atrp Solutions Inc Macromoleculas estrellas compatibles con tensoactivos.
CN114642735A (zh) 2015-01-21 2022-06-21 菲泽尔克斯公司 用于将治疗剂和诊断剂递送到细胞中的方法、组合物和系统
EP3562510A4 (en) 2016-12-30 2021-01-06 Genevant Sciences GmbH BRANCHED PEG MOLECULES AND ASSOCIATED COMPOSITIONS AND PROCEDURES

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE744162A (fr) 1969-01-16 1970-06-15 Fuji Photo Film Co Ltd Procede d'encapsulage
US3881991A (en) 1969-01-24 1975-05-06 Hayashibara Co Process for producing amylose powders having a mean degree of polymerization between 20{14 30
DE2010115A1 (de) 1970-03-04 1971-09-16 Farbenfabriken Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Mikrogranulaten
US4389330A (en) 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
US4713249A (en) 1981-11-12 1987-12-15 Schroeder Ulf Crystallized carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof
SE459005B (sv) 1985-07-12 1989-05-29 Aake Rikard Lindahl Saett att framstaella sfaeriska polymerpartiklar
GB2209937B (en) 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
JP2670680B2 (ja) 1988-02-24 1997-10-29 株式会社ビーエムジー 生理活性物質含有ポリ乳酸系微小球およびその製造法
US5019400A (en) 1989-05-01 1991-05-28 Enzytech, Inc. Very low temperature casting of controlled release microspheres
AU5741590A (en) 1989-05-04 1990-11-29 Southern Research Institute Improved encapsulation process and products therefrom
DK168790D0 (sv) 1990-07-13 1990-07-13 Novo Nordisk As
DE69220317T2 (de) 1991-10-01 1997-10-16 Takeda Chemical Industries Ltd Mikropartikeln-Zusammenfassung zur verlängerten Freigabe und Herstellung derselbe
US5470582A (en) 1992-02-07 1995-11-28 Syntex (U.S.A.) Inc. Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles
CA2136307A1 (en) 1992-04-20 1993-10-28 Bruce K. Redding, Jr. Method and apparatus for the modification of starch and other polymers
EP1013270A3 (en) 1992-12-02 2001-03-28 Alkermes Controlled Therapeutics, Inc. Controlled release growth hormone containing microspheres
ES2113094T3 (es) 1993-03-09 1998-04-16 Epic Therapeutics Inc Las microparticulas macromoleculares y metodos de obtencion.
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
DE4434877A1 (de) 1994-09-29 1996-04-04 Fresenius Ag Verfahren zur Herstellung von Stärkeabbauprodukten
KR100201352B1 (ko) 1995-03-16 1999-06-15 성재갑 단일주사 백신 제형
SE505146C2 (sv) 1995-10-19 1997-06-30 Biogram Ab Partiklar för fördröjd frisättning
US5792477A (en) 1996-05-07 1998-08-11 Alkermes Controlled Therapeutics, Inc. Ii Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent
US5959102A (en) 1997-06-30 1999-09-28 Rutgers University Starch purification by thermally tolerant broad pH range proteolytic enzymes
SE512663C2 (sv) 1997-10-23 2000-04-17 Biogram Ab Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
JPH11302156A (ja) 1998-04-16 1999-11-02 Tanabe Seiyaku Co Ltd ポリペプチドの微粒子化方法

Also Published As

Publication number Publication date
SE0003615L (sv) 2002-04-07
US20030211167A1 (en) 2003-11-13
SE517421C2 (sv) 2002-06-04
US20020044976A1 (en) 2002-04-18
US6706288B2 (en) 2004-03-16
US6692770B2 (en) 2004-02-17

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